Antonella Fioravanti

Summary

Country: Italy

Publications

  1. doi Phytothermotherapy in osteoarthritis: a randomized controlled clinical trial
    Antonella Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunology, University of Siena, Viale Bracci 1, Siena, Italy
    J Altern Complement Med 17:407-12. 2011
  2. doi Short- and long-term effects of mud-bath treatment on hand osteoarthritis: a randomized clinical trial
    Antonella Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Viale Bracci, 1, 53100, Siena, Italy
    Int J Biometeorol 58:79-86. 2014
  3. doi Circulating levels of adiponectin, resistin, and visfatin after mud-bath therapy in patients with bilateral knee osteoarthritis
    Antonella Fioravanti
    Department of Medicine, Surgery and Neuroscience, Rheumatology Unit, University of Siena, Le Scotte Policlinico, Viale Bracci 1, 53100, Siena, Italy
    Int J Biometeorol 59:1691-700. 2015
  4. doi One-year follow-up of mud-bath therapy in patients with bilateral knee osteoarthritis: a randomized, single-blind controlled trial
    A Fioravanti
    Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Policlinico Le Scotte, Viale Bracci 1, 53100, Siena, Italy
    Int J Biometeorol 59:1333-43. 2015
  5. doi Clinical and biochemical effects of a 3-week program of diet combined with spa therapy in obese and diabetic patients: a pilot open study
    Antonella Fioravanti
    Department of Medicine, Surgery and Neuroscience, Rheumatology Unit, University of Siena, Le Scotte Policlinico, Viale Bracci 1, 53100, Siena, Italy
    Int J Biometeorol 59:783-9. 2015
  6. doi Bradykinin and its role in osteoarthritis
    L De Falco
    Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy
    Reumatismo 65:97-104. 2013
  7. ncbi In vitro effects of VA441, a new selective cyclooxygenase-2 inhibitor, on human osteoarthritic chondrocytes exposed to IL-1β
    Antonella Fioravanti
    Department of Clinical Medicine and Immunology, Rheumatology Unit, University of Siena, Italy
    J Pharmacol Sci 120:6-14. 2012
  8. doi Efficacy of balneotherapy on pain, function and quality of life in patients with osteoarthritis of the knee
    Antonella Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy
    Int J Biometeorol 56:583-90. 2012
  9. doi Treatment of erosive osteoarthritis of the hands by intra-articular infliximab injections: a pilot study
    Antonella Fioravanti
    Unit of Rheumatology, Department of Clinical Medicine and Immunological Sciences, University of Siena, Viale Bracci 1, 53100, Siena, Italy
    Rheumatol Int 29:961-5. 2009
  10. ncbi Phytothermotherapy: a possible complementary therapy for fibromyalgia patients
    A Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Italy
    Clin Exp Rheumatol 27:S29-32. 2009

Collaborators

Detail Information

Publications58

  1. doi Phytothermotherapy in osteoarthritis: a randomized controlled clinical trial
    Antonella Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunology, University of Siena, Viale Bracci 1, Siena, Italy
    J Altern Complement Med 17:407-12. 2011
    ....
  2. doi Short- and long-term effects of mud-bath treatment on hand osteoarthritis: a randomized clinical trial
    Antonella Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Viale Bracci, 1, 53100, Siena, Italy
    Int J Biometeorol 58:79-86. 2014
    ..Tolerability of spa therapy seemed to be good. In conclusion, our results confirm that the beneficial effects of spa therapy in patients with hand OA last over time. ..
  3. doi Circulating levels of adiponectin, resistin, and visfatin after mud-bath therapy in patients with bilateral knee osteoarthritis
    Antonella Fioravanti
    Department of Medicine, Surgery and Neuroscience, Rheumatology Unit, University of Siena, Le Scotte Policlinico, Viale Bracci 1, 53100, Siena, Italy
    Int J Biometeorol 59:1691-700. 2015
    ..However, it remains to be clarified which of the mechanisms of action of MBT may have determined the changes in serum levels of adiponectin and resistin that we observed...
  4. doi One-year follow-up of mud-bath therapy in patients with bilateral knee osteoarthritis: a randomized, single-blind controlled trial
    A Fioravanti
    Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Policlinico Le Scotte, Viale Bracci 1, 53100, Siena, Italy
    Int J Biometeorol 59:1333-43. 2015
    ..Mud-bath therapy can represent a useful backup to pharmacologic treatment of knee OA or a valid alternative for patients who do not tolerate pharmacological treatments...
  5. doi Clinical and biochemical effects of a 3-week program of diet combined with spa therapy in obese and diabetic patients: a pilot open study
    Antonella Fioravanti
    Department of Medicine, Surgery and Neuroscience, Rheumatology Unit, University of Siena, Le Scotte Policlinico, Viale Bracci 1, 53100, Siena, Italy
    Int J Biometeorol 59:783-9. 2015
    ..So, a cycle of mud-bath therapy associated with a controlled diet may be a promising treatment for obesity and type 2 diabetes decreasing body weight and many risk factors for atherosclerosis and metabolic syndrome. ..
  6. doi Bradykinin and its role in osteoarthritis
    L De Falco
    Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy
    Reumatismo 65:97-104. 2013
    ..However, more in vitro, animal model and clinical studies, are needed to better understand the mechanisms of action as well as the efficacy and tolerability of the B2 receptor antagonists in OA. ..
  7. ncbi In vitro effects of VA441, a new selective cyclooxygenase-2 inhibitor, on human osteoarthritic chondrocytes exposed to IL-1β
    Antonella Fioravanti
    Department of Clinical Medicine and Immunology, Rheumatology Unit, University of Siena, Italy
    J Pharmacol Sci 120:6-14. 2012
    ..Our data suggest that VA441 and celecoxib may have a beneficial effect on chondrocyte metabolism...
  8. doi Efficacy of balneotherapy on pain, function and quality of life in patients with osteoarthritis of the knee
    Antonella Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy
    Int J Biometeorol 56:583-90. 2012
    ..Balneotherapy can represent a useful backup to pharmacological treatment of knee OA or a valid alternative for patients who do not tolerate pharmacological treatments...
  9. doi Treatment of erosive osteoarthritis of the hands by intra-articular infliximab injections: a pilot study
    Antonella Fioravanti
    Unit of Rheumatology, Department of Clinical Medicine and Immunological Sciences, University of Siena, Viale Bracci 1, 53100, Siena, Italy
    Rheumatol Int 29:961-5. 2009
    ..No local or systemic adverse reactions were recorded. Our study shows the symptomatic effect and a possible disease modifying action of i.a. infliximab in erosive osteoarthritis of the hands...
  10. ncbi Phytothermotherapy: a possible complementary therapy for fibromyalgia patients
    A Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Italy
    Clin Exp Rheumatol 27:S29-32. 2009
    ..The aim of this study was to assess the efficacy and tolerability of a cycle of phytothermotherapy through a single-blind, controlled, randomised trial, in patients with primary FMS...
  11. ncbi Morphological, immunocytochemical and biochemical studies in human osteoarthritic chondrocytes exposed to IL-1b and cyclical hydrostatic pressure
    A Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Italy
    Clin Exp Rheumatol 25:690-5. 2007
    ....
  12. doi Effects of spa therapy on serum leptin and adiponectin levels in patients with knee osteoarthritis
    Antonella Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Viale Bracci, 1, 53100, Siena, Italy
    Rheumatol Int 31:879-82. 2011
    ..Whether this effect may play a potential role in OA needs further investigations...
  13. doi Mechanisms of action of spa therapies in rheumatic diseases: what scientific evidence is there?
    Antonella Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunology, University of Siena, Viale Bracci 1, 53100 Siena, Italy
    Rheumatol Int 31:1-8. 2011
    ....
  14. ncbi Effect of continuous high hydrostatic pressure on the morphology and cytoskeleton of normal and osteoarthritic human chondrocytes cultivated in alginate gels
    A Fioravanti
    Department of Clinical Medicine and Immunological Sciences, Rheumatology Unit, University of Siena, Siena, Italy
    Clin Exp Rheumatol 23:847-53. 2005
    ..To investigate the effect of continuous high hydrostatic pressure on the cell ultrastructure and cytoskeleton of cultivated normal and osteoarthritic (OA) human chondrocytes...
  15. ncbi Methods used to assess clinical outcome and quality of life in osteoarthritis
    Antonella Fioravanti
    Institute of Rheumatology, University of Siena, Policlinico Le Scotte, Siena, Italy
    Semin Arthritis Rheum 34:70-2. 2005
  16. ncbi Effect of hyaluronic acid (MW 500-730 kDa) on proteoglycan and nitric oxide production in human osteoarthritic chondrocyte cultures exposed to hydrostatic pressure
    A Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Le Scotte Policlinico, Siena, Italy
    Osteoarthritis Cartilage 13:688-96. 2005
    ....
  17. ncbi Morphological and cytoskeletal aspects of cultivated normal and osteoarthritic human articular chondrocytes after cyclical pressure: a pilot study
    A Fioravanti
    Institute of Rheumatology, University of Siena, Siena, Italy
    Clin Exp Rheumatol 21:739-46. 2003
    ..This study investigated the effect of hydrostatic cyclical pressure on the cell ultrastructure and cytoskeleton of normal and osteoarthritis (OA) human cultivated chondrocytes in vitro...
  18. ncbi Clinical efficacy and cost-effectiveness evidence of spa therapy in osteoarthritis. The results of "Naiade" Italian Project
    A Fioravanti
    Institute of Rheumatology, University of Siena, Siena, Italy
    Panminerva Med 45:211-7. 2003
    ..In this study the authors refer to the results obtained in osteoarthritis (OA)...
  19. ncbi Leptin, adiponectin, resistin, visfatin serum levels and idiopathic recurrent pericarditis: biomarkers of disease activity? A preliminary report
    Luca Cantarini
    University of Siena, Siena, Italy
    Clin Exp Rheumatol 31:207-12. 2013
    ..This study investigated whether serum leptin, resistin, visfatin and adiponectin are increased in IRAP versus healthy controls and if their levels correlate with parameters of disease activity...
  20. doi Short- and long-term effects of spa therapy in knee osteoarthritis
    Antonella Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy
    Am J Phys Med Rehabil 89:125-32. 2010
    ..To assess both the short- and long-term effectiveness of spa therapy in patients with primary knee osteoarthritis in a prospective, randomized, single-blinded, controlled trial...
  21. doi Effects of gold and silver nanoparticles in cultured human osteoarthritic chondrocytes
    Nicola Antonio Pascarelli
    Department of Medicine, Surgery and Neuroscience, Rheumatology Unit, University of Siena, Italy
    J Appl Toxicol 33:1506-13. 2013
    ..Our in vitro studies, although preliminary, suggest that engineered Au and Ag-NPs appear to be harmful for human osteoarthritic chondrocytes in high concentrations (160-250 μM)...
  22. pmc Effects of regenerative radioelectric asymmetric conveyer treatment on human normal and osteoarthritic chondrocytes exposed to IL-1β. A biochemical and morphological study
    Giulia Collodel
    Department of Biomedical Sciences Applied Biology, University of Siena, Siena, Italy
    Clin Interv Aging 8:309-16. 2013
    ....
  23. doi Raloxifene protects cultured human chondrocytes from IL-1β induced damage: a biochemical and morphological study
    Laura Tinti
    Department of Clinical Medicine and Immunological Sciences, Rheumatology Unit, University of Siena, Italy
    Eur J Pharmacol 670:67-73. 2011
    ..The results of the biochemical evaluation were confirmed by TEM. Our data suggest that raloxifene may have a potential chondroprotective role in osteoarthritis...
  24. ncbi Therapeutic effect of spa therapy and short wave therapy in knee osteoarthritis: a randomized, single blind, controlled trial
    Luca Cantarini
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy
    Rheumatol Int 27:523-9. 2007
    ..Our study demonstrated the superiority of arsenical ferruginous spa therapy compared to short wave therapy in the treatment of osteoarthritis of the knee, probably in relationship to the specific effects of the minerals in this water...
  25. doi Possible chondroprotective effect of canakinumab: an in vitro study on human osteoarthritic chondrocytes
    Sara Cheleschi
    Department of Medicine, Surgery and Neuroscience, Rheumatology Unit, University of Siena, Italy Electronic address
    Cytokine 71:165-72. 2015
    ..We showed that canakinumab counteracts the negative effects of TNF-α on OA chondrocyte cultures and may have a potential chondroprotective role in OA. ..
  26. pmc Serum amyloid A circulating levels and disease activity in patients with juvenile idiopathic arthritis
    Luca Cantarini
    Rheumatology Unit, Department of Clinical Medicine and Immunologic Sciences, University of Siena, Siena, Italy
    Yonsei Med J 53:1045-8. 2012
    ..We also discerned SAA to be a more sensitive laboratory marker than ESR and CRP for evaluating the presence and number of active joints. We suggest that SAA can be used as an additional indicator of disease activity in JIA...
  27. ncbi Effect of hydrostatic pressure of various magnitudes on osteoarthritic chondrocytes exposed to IL-1beta
    Antonella Fioravanti
    Department of Clinical Medicine and Immunological Sciences, Rheumatology Unit, University of Siena, Siena, Italy
    Indian J Med Res 132:209-17. 2010
    ..The present study was undertaken to evaluate the in vitro effects of cyclical low HP (1-5 MPa) and continuous high HP (24 MPa) applied in the presence or absence of interleukin (IL)-1beta on human osteoarthritis (OA) chondrocytes...
  28. pmc Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/β-Catenin Pathway
    Sara Cheleschi
    Department of Medicine, Surgery and Neuroscience, Rheumatology Unit, University of Siena, Policlinico Le Scotte, Viale Bracci 1, 53100 Siena, Italy
    Int J Mol Sci 18:. 2017
    ..In conclusion, in OA chondrocytes, HP restores the expression levels of some miRNAs, downregulates MMP-13, ADAMTS-5, and HDAC-4, and modulates the Wnt/β-catenin pathway activation...
  29. ncbi Do MicroRNAs have a key epigenetic role in osteoarthritis and in mechanotransduction?
    Anna de Palma
    Department of Medicine, Surgery and Neurosciences, University of Siena and Department of Medical Biotechnologies, University of Siena, Italy
    Clin Exp Rheumatol . 2017
    ..Herein, we have reviewed the current state of research on miRNAs in cartilage homeostasis and OA pathogenesis and their potential clinical applications...
  30. pmc Phase Ib study of poly-epitope peptide vaccination to thymidylate synthase (TSPP) and GOLFIG chemo-immunotherapy for treatment of metastatic colorectal cancer patients
    Pierpaolo Correale
    Unit of Radiotherapy, Department of Oncology, University of Siena, Italy
    Oncoimmunology 5:e1101205. 2016
    ..DL0 = 8 vs. 16 mo, p = 0.049]. The promising long-term survival produced by the sequential treatment module deserves further phase II evaluation...
  31. doi Chondroprotective effect of three different classes of anti-inflammatory agents on human osteoarthritic chondrocytes exposed to IL-1β
    Sara Cheleschi
    Department of Medicine, Surgery and Neuroscience, Rheumatology Unit, University of Siena, Policlinico Le Scotte, Viale Bracci 1, 53100 Siena, Italy Electronic address
    Int Immunopharmacol 28:794-801. 2015
    ..Our data suggest that VA694, Naproxcinod and Naproxen, exert anti-inflammatory and chondroprotective effects on OA chondrocytes...
  32. ncbi Circulating levels of the adipokines vaspin and omentin in patients with juvenile idiopathic arthritis, and relation to disease activity
    Luca Cantarini
    Department of Clinical Medicine and Immunologic Sciences, University of Siena, Italy
    Clin Exp Rheumatol 29:1044-8. 2011
    ..The aims of our study were to evaluate their serum levels in patients affected by juvenile idiopathic arthritis (JIA), in comparison to healthy controls, and to correlate circulating levels to parameters of disease activity...
  33. doi May spa therapy be a valid opportunity to treat hand osteoarthritis? A review of clinical trials and mechanisms of action
    Nicola Angelo Fortunati
    Spa Centre of Fonteverde Natural Spa Resort, San Casciano Terme, Siena, Italy
    Int J Biometeorol 60:1-8. 2016
    ..Spa therapy seems to have a role in the treatment of hand OA. However, additional RCTs are necessary to clarify the mechanisms of action and the effects of the application of thermal treatments. ..
  34. ncbi The Emerging Role of Bradykinin in the Pathogenesis of Osteoarthritis and its Possible Clinical Implications
    Sara Tenti
    Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, Policlinico Le Scotte, Viale Bracci, 1, 53100 Siena, Italy
    Curr Rheumatol Rev 12:177-184. 2016
    ..There is a need for further preclinical and clinical trials to better explain the mechanisms of action and the efficacy and tolerability of the B2 receptor antagonists in OA...
  35. doi Intravenous immunoglobulins and antiphospholipid syndrome: How, when and why? A review of the literature
    Sara Tenti
    Rheumatology Unit, Policlinico Le Scotte, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy
    Autoimmun Rev 15:226-35. 2016
    ..Anyway, in some cases we also found controversial results that claim the need of further well-designed studies to definitely state the efficacy and tolerability of IVIG in CAPS, obstetric and non-APS. ..
  36. pmc Changes in Ultrastructure and Cytoskeletal Aspects of Human Normal and Osteoarthritic Chondrocytes Exposed to Interleukin-1β and Cyclical Hydrostatic Pressure
    Nicola Antonio Pascarelli
    Department of Medicine, Surgery and Neuroscience, Rheumatology Unit, University of Siena, Policlinico Le Scotte, Viale Bracci 1, Siena 53100, Italy
    Int J Mol Sci 16:26019-34. 2015
    ..Our results showed structural differences at nuclear, cytoplasmic and cytoskeletal level between normal and OA chondrocytes. IL-1β induced ultrastructural and cytoskeletal modifications, counteracted by a cyclical low HP. ..
  37. doi What about strontium ranelate in osteoarthritis? Doubts and securities
    Sara Tenti
    Department of Medicine, Surgery and Neurosciences, Rheumatology Unit, University of Siena, Siena, Italy
    Mod Rheumatol 24:881-4. 2014
    ..Additionally, there is a need for further investigations to establish the optimal dosage and to better clarify the mechanism of action of SR in OA. ..
  38. doi Granulomatosis with polyangiitis and intravenous immunoglobulins: a case series and review of the literature
    Giacomo Maria Guidelli
    Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy Electronic address
    Autoimmun Rev 14:659-64. 2015
    ..We also discussed the beneficial effects of intravenous immunoglobulins in patients suffering from granulomatosis with polyangiitis, reporting the previously published data. ..
  39. ncbi Long-term treatment of antiphospholipid syndrome with intravenous immunoglobulin in addition to conventional therapy
    Sara Tenti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Italy
    Clin Exp Rheumatol 31:877-82. 2013
    ....
  40. ncbi Effects of mud-bath treatment on fibromyalgia patients: a randomized clinical trial
    Antonella Fioravanti
    Department of Clinical Medicine and Immunogical Sciences, University of Siena, Siena, Italy
    Rheumatol Int 27:1157-61. 2007
    ..Mud packs were well tolerated and no drop-outs were recorded. Our results suggest the efficacy and the tolerability of mud-bath treatment in primary FS...
  41. doi Spa therapy: can be a valid option for treating knee osteoarthritis?
    Sara Tenti
    Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, Policlinico Le Scotte, University of Siena, Viale Bracci 1, 53100, Siena, Italy
    Int J Biometeorol 59:1133-43. 2015
    ..In conclusion, spa therapy seems to have a role in the treatment of knee OA. Additional RCTs and further studies of mechanisms of action with high methodological quality are necessary to prove the effects of spa therapy...
  42. ncbi Sjögren's syndrome and aromatase inhibitors treatment: is there a link?
    Giacomo Maria Guidelli
    Department of Clinical Medicine and Immunological Science, Rheumatology Unit, University of Siena, Italy
    Clin Exp Rheumatol 31:653-4. 2013
    ....
  43. pmc Simvastatin reduces MMP-3 level in interleukin 1beta stimulated human chondrocyte culture
    P E Lazzerini
    Department of Clinical Medicine and Immunological Sciences, Division of Clinical Immunology, University of Siena, Policlinico Le Scotte, 53100 Siena, Italy
    Ann Rheum Dis 63:867-9. 2004
    ..We thus decided to investigate the effect of simvastatin on the production of MMP-3 from cultured interleukin (IL)1 stimulated human chondrocytes...
  44. doi Human osteoarthritic chondrocytes exposed to extremely low-frequency electromagnetic fields (ELF) and therapeutic application of musically modulated electromagnetic fields (TAMMEF) systems: a comparative study
    Claudio Corallo
    Department of Internal Medicine, Endocrine and Metabolic Sciences and Biochemistry, University of Siena, Ospedale S Maria alle Scotte, Viale Bracci, 53100 Siena, Italy
    Rheumatol Int 33:1567-75. 2013
    ..In conclusion, EMFs are effective and safe for OA chondrocytes. TAMMEF can positively interfere with OA chondrocytes representing an innovative non-pharmacological approach to treat OA...
  45. ncbi A randomized, double-blind, multicenter trial of nimesulide-beta-cyclodextrin versus naproxen in patients with osteoarthritis
    Antonella Fioravanti
    Institute of Rheumatology, University of Siena, Italy
    Clin Ther 24:504-19. 2002
    ..No data are presently available on the medium-term management of this disease with an on-demand treatment regimen, which nevertheless reflects medical practice...
  46. doi Efficacy of alendronate in the treatment of the SAPHO syndrome
    Antonella Fioravanti
    Department of Clinical Medicine and Immunologic Sciences, Policlinico Le Scotte, University of Siena, Siena, Italy
    J Clin Rheumatol 14:183-4. 2008
  47. pmc Biochemical and morphological study of human articular chondrocytes cultivated in the presence of pulsed signal therapy
    A Fioravanti
    Institute of Rheumatology, University of Siena, Italy
    Ann Rheum Dis 61:1032-3. 2002
  48. doi Phase I trial of thymidylate synthase poly-epitope peptide (TSPP) vaccine in advanced cancer patients
    Maria Grazia Cusi
    Department of Medical Biotechnologies, Siena University, Siena, Italy
    Cancer Immunol Immunother 64:1159-73. 2015
    ..Taken together, our findings provide the framework for the evaluation of the TSPP anti-tumor activity in further disease-oriented clinical trials...
  49. pmc Fibromyalgia syndrome and spa therapy: myth or reality?
    Giacomo M Guidelli
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Italy
    Clin Med Insights Arthritis Musculoskelet Disord 5:19-26. 2012
    ..The objective of this review is to summarize the currently available information on clinical effects and mechanism of action of spa therapy in FS. We also provide some suggestions for further development in this area...
  50. ncbi Linear scleroderma associated with progressive brain atrophy
    Salvatore Grosso
    Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Viale M Bracci Le scotte, 53100 Siena, Italy
    Brain Dev 25:57-61. 2003
    ..Our observations suggest that neuroimaging studies should be considered in all patients with linear scleroderma, and such studies become necessary when neurological symptoms occur...
  51. doi Immunity feedback and clinical outcome in colon cancer patients undergoing chemoimmunotherapy with gemcitabine + FOLFOX followed by subcutaneous granulocyte macrophage colony-stimulating factor and aldesleukin (GOLFIG-1 Trial)
    Pierpaolo Correale
    Section of Medical Oncology, Department Giorgio Segre of Pharmacology, Rheumatology Unit, Siena University School of Medicine, Siena, Italy
    Clin Cancer Res 14:4192-9. 2008
    ..We have thus investigated the immunobiological feedback to the treatment and its possible correlation with the clinical outcome of these patients...
  52. ncbi In vitro effects of chondroitin sulfate
    A Fioravanti
    Rheumatology Unit, Department of Clinical Medicine and Immunological Sciences, University of Siena, Italy
    Adv Pharmacol 53:449-65. 2006
  53. ncbi Capillaroscopic findings in erosive and nodal osteoarthritis of the hands
    A Fioravanti
    Institute of Rheumatology, University of Siena, Italy
    Clin Rheumatol 20:174-6. 2001
    ..The authors discuss the significance of these abnormalities and the possible relationship between EOA and psoriatic arthritis...
  54. ncbi Magnetic resonance imaging in Tietze's syndrome
    L Volterrani
    Department of Human Pathology and Oncology, Department of Clinical and Immunological Science, University of Siena, Siena, Italy
    Clin Exp Rheumatol 26:848-53. 2008
    ..To evaluate the usefulness of magnetic resonance imaging (MRI) in Tietze's syndrome which, to our knowledge, has not previously been reported in the literature...
  55. ncbi Sonographic study of calcaneal entheses in erosive osteoarthritis, nodal osteoarthritis, rheumatoid arthritis and psoriatic arthritis
    P Falsetti
    Institute of Rheumatology, University of Siena, Policlinico Le Scotte Viale Bracci, 53100, Siena, Italy
    Scand J Rheumatol 32:229-34. 2003
    ..A comparison between US results and radiography was also made...
  56. ncbi Occurrence of autoimmunity in a long-term survivor with metastatic colon carcinoma treated with a new chemo-immunotherapy regimen
    P Correale
    Section of Medical Oncology, Department of Clinical Medicine and Immunological Sciences, Siena University School of Medicine, Siena, Italy
    J Chemother 20:278-81. 2008
    ..In this manuscript we describe a clinical case concerning a patient with metastatic colon carcinoma who responded to the GOLFIG regimen, showed symptoms of autoimmunity [Discoid Lupus Erythematosus (DLE)] and had a very long survival...
  57. ncbi Intermittent treatment of knee osteoarthritis with oral chondroitin sulfate: a one-year, randomized, double-blind, multicenter study versus placebo
    Daniel Uebelhart
    Department of Rheumatology, Institute of Physical Medicine, University Hospital Zurich, Switzerland
    Osteoarthritis Cartilage 12:269-76. 2004
    ..To investigate the efficacy and tolerability of a 3-month duration, twice a-year, intermittent treatment with oral chondroitin sulfate (CS) in knee osteoarthritis (OA) patients...
  58. ncbi Anthraquinone-2,6-disulfonic acid as a disease-modifying osteoarthritis drug: an in vitro and in vivo study
    Lucia Savarino
    Laboratory for Pathophysiology of Orthopaedic Implants, Istituti Ortopedici Rizzoli, Bologna, Italy
    Clin Orthop Relat Res 461:231-7. 2007
    ..Our data suggest anthraquinone-2,6-disulfonic acid is worth exploring for treating osteoarthritis...