Filomena Morisco

Summary

Affiliation: Federico II University
Country: Italy

Publications

  1. pmc Lack of evidence of viral reactivation in HBsAg-negative HBcAb-positive and HCV patients undergoing immunosuppressive therapy for psoriasis
    Filomena Morisco
    Department of Clinical Medicine and Surgery, Gastroenterology Unit, University of Naples Federico II, Via S Pansini, 5, Naples, 80131, Italy
    BMC Gastroenterol 14:214. 2014
  2. pmc Rapid "breath-print" of liver cirrhosis by proton transfer reaction time-of-flight mass spectrometry. A pilot study
    Filomena Morisco
    Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy
    PLoS ONE 8:e59658. 2013
  3. pmc Sustained virological response: a milestone in the treatment of chronic hepatitis C
    Filomena Morisco
    Gastroenterology Unit, Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, 80131 Naples, Italy
    World J Gastroenterol 19:2793-8. 2013
  4. doi request reprint Effect of immunosuppressive therapy on patients with inflammatory bowel diseases and hepatitis B or C virus infection
    F Morisco
    Clinical and Experimental Medicine, Gastroenterology Unit, University of Naples Federico II, Naples, Italy
    J Viral Hepat 20:200-8. 2013
  5. ncbi request reprint Tomato-based functional food as interferon adjuvant in HCV eradication therapy
    Filomena Morisco
    Department of Food Science, University of Naples, Federico II, Italy
    J Clin Gastroenterol 38:S118-20. 2004
  6. ncbi request reprint Oxidative status in chronic hepatitis C: the influence of antiviral therapy and prognostic value of serum hydroperoxide assay
    Filomena Morisco
    Department of Food Science, University of Naples Federico II, Parco Gussone 80055, Portici, Italy
    Free Radic Res 38:573-80. 2004
  7. ncbi request reprint Efficacy of loco-regional ablation therapy of HCC in a population of liver transplanted patients
    Filomena Morisco
    Liver Transplant and Hepatobiliary Medicine, Royal Free Hospital, London, UK
    Dig Dis Sci 53:1131-7. 2008
  8. doi request reprint Hepatitis B virus infection and immunosuppressive therapy in patients with inflammatory bowel disease
    Filomena Morisco
    Department of Food Science, University of Naples Federico II, Italy
    Dig Liver Dis 43:S40-8. 2011
  9. doi request reprint Etiology of and risk factors for transient and persistent aminotransferase elevation in a population of virus-free blood donors: a multicentre study
    Filomena Morisco
    Department of Food Science, University of Naples Federico II, 80055 Portici, Naples, Italy
    Dig Liver Dis 42:441-5. 2010
  10. doi request reprint Retrospective, observational, multicentre study on an Italian population affected by chronic hepatitis C who failed to clear HCV-RNA after the combined therapy (PEG-IFN and ribavirin): NADIR study
    F Morisco
    Clinical and Experimental Medicine, Gastroenterology Unit, University of Naples Federico II, Naples, Italy
    J Viral Hepat 17:427-34. 2010

Collaborators

Detail Information

Publications32

  1. pmc Lack of evidence of viral reactivation in HBsAg-negative HBcAb-positive and HCV patients undergoing immunosuppressive therapy for psoriasis
    Filomena Morisco
    Department of Clinical Medicine and Surgery, Gastroenterology Unit, University of Naples Federico II, Via S Pansini, 5, Naples, 80131, Italy
    BMC Gastroenterol 14:214. 2014
    ..The aim of our study was to assess the prevalence of HBV and HCV infection in patients with psoriasis and to evaluate the effects of IT during the course of the infection...
  2. pmc Rapid "breath-print" of liver cirrhosis by proton transfer reaction time-of-flight mass spectrometry. A pilot study
    Filomena Morisco
    Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy
    PLoS ONE 8:e59658. 2013
    ..ROC (Receiver Operating Characteristic) analysis was performed considering three contrast groups: CP vs CTRL, CP-A vs CTRL and CP-A vs CP-B+C. In these comparisons monoterpene and N-compound showed the best diagnostic performance...
  3. pmc Sustained virological response: a milestone in the treatment of chronic hepatitis C
    Filomena Morisco
    Gastroenterology Unit, Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, 80131 Naples, Italy
    World J Gastroenterol 19:2793-8. 2013
    ..To evaluate the long-term eradication of hepatitis C virus (HCV) infection and liver-related complications in chronically infected patients that have achieved sustained virological response...
  4. doi request reprint Effect of immunosuppressive therapy on patients with inflammatory bowel diseases and hepatitis B or C virus infection
    F Morisco
    Clinical and Experimental Medicine, Gastroenterology Unit, University of Naples Federico II, Naples, Italy
    J Viral Hepat 20:200-8. 2013
    ..We confirm the role of immunosuppressive therapy in HBV reactivation, but the impact on clinical course seems to be less relevant than previous reported...
  5. ncbi request reprint Tomato-based functional food as interferon adjuvant in HCV eradication therapy
    Filomena Morisco
    Department of Food Science, University of Naples, Federico II, Italy
    J Clin Gastroenterol 38:S118-20. 2004
    ..The authors conducted a study to verify whether supplementation with an antioxidant-rich tomato-based functional food reduces anemia during pegylated interferon and ribavirin therapy for chronic hepatitis C...
  6. ncbi request reprint Oxidative status in chronic hepatitis C: the influence of antiviral therapy and prognostic value of serum hydroperoxide assay
    Filomena Morisco
    Department of Food Science, University of Naples Federico II, Parco Gussone 80055, Portici, Italy
    Free Radic Res 38:573-80. 2004
    ..The effect of alpha-interferon (alpha-IFN) and ribavirin (RBV) treatment on oxidative status in chronic hepatitis C (CHC) is unknown...
  7. ncbi request reprint Efficacy of loco-regional ablation therapy of HCC in a population of liver transplanted patients
    Filomena Morisco
    Liver Transplant and Hepatobiliary Medicine, Royal Free Hospital, London, UK
    Dig Dis Sci 53:1131-7. 2008
    ..The aim of this study was: to evaluate if LAT was able to induce complete necrosis of tumour mass; to determine the tumour recurrence rate after LT and factors associated with recurrence...
  8. doi request reprint Hepatitis B virus infection and immunosuppressive therapy in patients with inflammatory bowel disease
    Filomena Morisco
    Department of Food Science, University of Naples Federico II, Italy
    Dig Liver Dis 43:S40-8. 2011
    ..The aim of this paper is to provide a systematic review of the literature to underline the main aspects of HBV infection and reactivation in patients affected by IBD treated with conventional or biological immunosuppressive drugs...
  9. doi request reprint Etiology of and risk factors for transient and persistent aminotransferase elevation in a population of virus-free blood donors: a multicentre study
    Filomena Morisco
    Department of Food Science, University of Naples Federico II, 80055 Portici, Naples, Italy
    Dig Liver Dis 42:441-5. 2010
    ..We evaluated the etiology and risk factors for transient and persistently elevated aspartate and/or alanine aminotransferase levels in virus-free blood donors...
  10. doi request reprint Retrospective, observational, multicentre study on an Italian population affected by chronic hepatitis C who failed to clear HCV-RNA after the combined therapy (PEG-IFN and ribavirin): NADIR study
    F Morisco
    Clinical and Experimental Medicine, Gastroenterology Unit, University of Naples Federico II, Naples, Italy
    J Viral Hepat 17:427-34. 2010
    ..Co-morbidities are unable to determine the type of treatment failure and inadequate adherence to therapy mostly affects patients older than 65 years of age...
  11. doi request reprint Garlic extract attenuating rat liver fibrosis by inhibiting TGF-β1
    Giuseppe D'Argenio
    Gastroenterology Unit, Department of Clinical and Experimental Medicine, Federico II University of Naples, Italy
    Clin Nutr 32:252-8. 2013
    ..In the present study we aimed to evaluate the potential of GE in the regression of liver fibrosis and the underlining mechanism...
  12. doi request reprint Garlic extract prevents CCl(4)-induced liver fibrosis in rats: The role of tissue transglutaminase
    Giuseppe D'Argenio
    Gastroenterology Unit, Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy
    Dig Liver Dis 42:571-7. 2010
    ..Garlic extract contains many compounds structurally related to cystamine. We investigated the anti-fibrotic effect of garlic extract and cystamine as specific tissue transglutaminase inhibitors...
  13. doi request reprint Coffee reduces liver damage in a rat model of steatohepatitis: the underlying mechanisms and the role of polyphenols and melanoidins
    Paola Vitaglione
    Department of Food Science, University of Napoli Federico II, Portici, Italy
    Hepatology 52:1652-61. 2010
    ....
  14. ncbi request reprint The addition of ribavirin to interferon-alpha therapy in patients with hepatitis C virus-related chronic hepatitis does not modify the thyroid autoantibody pattern but increases the risk of developing hypothyroidism
    Carlo Carella
    Department of Clinical and Experimental Medicine F Magrassi, Second University of Naples, Naples, Italy
    Eur J Endocrinol 146:743-9. 2002
    ..The aim of this study was to investigate whether the addition of ribavirin (RIBA) to interferon-alpha (IFN-alpha) therapy increases the risk of developing thyroid autoimmunity and/or dysfunction...
  15. ncbi request reprint Serum insulin-like growth factor I evaluation as a useful tool for predicting the risk of developing hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis: a prospective study
    Gherardo Mazziotti
    Department of Clinical and Experimental Medicine F Magrassi, Second University of Naples, Naples, Italy
    Cancer 95:2539-45. 2002
    ....
  16. pmc Hepatitis B and C virus reactivation in immunosuppressed patients with inflammatory bowel disease
    Stefano Sansone
    Stefano Sansone, Maria Guarino, Fabiana Castiglione, Antonio Rispo, Francesco Auriemma, Ilaria Loperto, Matilde Rea, Nicola Caporaso, Filomena Morisco, Gastroenterology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
    World J Gastroenterol 20:3516-24. 2014
    ..Thus, it seems clear that it is desirable to concentrate our efforts on prospective studies, not conducting further reviews of the literature in the continued absence of new evidence. ..
  17. doi request reprint Dietary trans-resveratrol bioavailability and effect on CCl4-induced liver lipid peroxidation
    Paola Vitaglione
    Department of Food Science, Gastroenterology Unit, Federico II University of Naples, Naples, Italy
    J Gastroenterol Hepatol 24:618-22. 2009
    ..Our aim was to investigate the bioavailability of t-Res from dietary sources and its effect on an animal model of carbon tetrachloride (CCl4)-induced liver lipid peroxidation...
  18. ncbi request reprint Incidence of side effects during therapy with different types of alpha interferon: a randomised controlled trial comparing recombinant alpha 2b versus leukocyte interferon in the therapy of naive patients with chronic hepatitis C
    Antonio Ascione
    Dept of Gastroenterology, Liver and Pancreatic Unit, Cardarelli Hospital, Naples, Italy
    Curr Pharm Des 8:977-80. 2002
    ....
  19. ncbi request reprint Foods and liver health
    Filomena Morisco
    Department of Food Science, University of Naples Federico II, Via Universita, 100, 80055 Portici Napoli, Italy
    Mol Aspects Med 29:144-50. 2008
    ....
  20. doi request reprint Lack of evidence that adherence to standard of care therapy improves survival in subjects with hepatocellular carcinoma in clinical practice
    Maria Guarino
    Department of Clinical Medicine and Surgery, Gastroenterology Unit, University of Naples Federico II, Italy
    J Med Virol 87:1368-76. 2015
    ..Strategies to help improve adherence to international guidelines for HCC in clinical practice are required...
  21. ncbi request reprint Dietary approach in the prevention and treatment of NAFLD
    Nicola Caporaso
    Clinical and Experimental Medicine, Gastroenterology Unit, University of Naples, Federico II, Naples, Italy
    Front Biosci (Landmark Ed) 17:2259-68. 2012
    ..The use of functional foods in NAFLD has been poorly studied and up to day only few reports are encouraging and incite the promotion of functional food approach on NAFLD prevention on the basis of food and nutritional genomics...
  22. doi request reprint Prevalence and risk factors of HCV infection in a metropolitan area in southern Italy: Tail of a cohort infected in past decades
    Filomena Morisco
    Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy
    J Med Virol 89:291-297. 2017
    ..HCV positive subjects born during the years 1945-1955 are those who may benefit, to a greater extent, to be identified in order to receive the new effective therapy. J. Med. Virol. 89:291-297, 2017. © 2016 Wiley Periodicals, Inc...
  23. ncbi request reprint Effect of Red Wine Polyphenols on the Expression of Transthyretin in Murine Choroid Plexus
    Gian C Tenore
    Department of Pharmacy, University of Naples Federico II, via D Montesano 49, 80131 Naples, Italy
    Curr Pharm Biotechnol 17:1008-15. 2016
    ....
  24. doi request reprint Coffee and liver health
    Filomena Morisco
    Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy
    J Clin Gastroenterol 48:S87-90. 2014
    ..It is unclear whether the benefits are significant enough to "treat" patients with chronic liver disease. While we await clarification, moderate daily unsweetened coffee use is a reasonable adjuvant to therapy for these patients. ..
  25. doi request reprint Impact of Diabetes on Outcomes of Sorafenib Therapy for Hepatocellular Carcinoma
    Giovan Giuseppe Di Costanzo
    Department of Transplantation Liver Unit, Cardarelli Hospital, via A Cardarelli 9, 80131, Naples, Italy
    Target Oncol 12:61-67. 2017
    ..Diabetics with non-HCC cancers are at higher risk of toxicity related to systemic therapy, but data on HCC are lacking...
  26. ncbi request reprint Concomitant interferon-alpha and chemotherapy in hepatitis C and colorectal cancer: a case report
    Ivan Gentile
    Department of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Via S Pansini 5, I 80131 Naples, Italy
    In Vivo 27:527-9. 2013
    ..Both treatments were well-tolerated and the patient completed the scheduled therapies. HCV infection was eradicated and the patient is free of neoplastic disease two years and 6 months after surgery. ..
  27. ncbi request reprint Review: gut microbiota and functional diseases of the gastrointestinal tract
    Nicola Imperatore
    Gastroenterology, Department of Clinical Medicine and Surgery, School of Medicine Federico II of Naples, Naples, Italy
    Minerva Gastroenterol Dietol . 2016
    ..Recent evidences have been highlighted the role of gut microbiota in the pathophysiology of the FGIDs...
  28. ncbi request reprint Increased serum reverse triiodothyronine levels at diagnosis of hepatocellular carcinoma in patients with compensated HCV-related liver cirrhosis
    Francesca Sorvillo
    Department of Clinical and Experimental Medicine F Magrassi and A Lanzara, Second University of Naples, Italy
    Clin Endocrinol (Oxf) 58:207-12. 2003
    ..The aim of this study was to investigate changes in thyroid hormone metabolism in relation to the development of hepatocellular carcinoma (HCC) in patients with HCV-related liver cirrhosis...
  29. ncbi request reprint Dietary antioxidant compounds and liver health
    Paola Vitaglione
    Dipartimento di Scienza degli Alimenti, Università di Napoli Federico II Parco Gussone Ed 84, Portici NA Italy
    Crit Rev Food Sci Nutr 44:575-86. 2004
    ..On the other hand contradictory results have been obtained with alpha-tocopherol, beta-carotene and trans-resveratrol. Quercetin, silymarin, esculetin and thyme and rosemary among phenolic compounds need further studies...
  30. ncbi request reprint Liver transplantation and recurrent hepatocellular carcinoma: predictive value of nodule size in a retrospective and explant study
    Alessandro Grasso
    Liver Transplantation and Hepatobiliary Medicine Unit, London UK, Royal Free Hospital London, United Kingdom
    Transplantation 81:1532-41. 2006
    ..Recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) remains a major cause of post-LT death...
  31. ncbi request reprint Use of N,N-dimethyl-p-phenylenediamine to evaluate the oxidative status of human plasma
    Veronica Verde
    Dipartimento di Scienza degli Alimenti, Universita di Napoli Federico II, Italy
    Free Radic Res 36:869-73. 2002
    ..The DMPD assay alone or in combination with analytical methods for assessing antioxidant capacity is suggested as a reliable tool to obtain information in pathologies related to oxidative stress...