Giovanni Esposito

Summary

Affiliation: Federico II University
Country: Italy

Publications

  1. ncbi request reprint Contemporary use and results of intra-aortic balloon pump counterpulsation
    Giuseppe Gargiulo
    Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy
    Minerva Cardioangiol 64:84-91. 2016
  2. doi request reprint Dermcidin: a skeletal muscle myokine modulating cardiomyocyte survival and infarct size after coronary artery ligation
    Giovanni Esposito
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Via Pansini 5, Naples 80131, Italy
    Cardiovasc Res 107:431-41. 2015
  3. ncbi request reprint Cardiac side effects of chemotherapy: state of art and strategies for a correct management
    Cinzia Perrino
    Division of Cardiology, Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Via Pansini 5, 80131 Naples, Italy
    Curr Vasc Pharmacol 12:106-16. 2014
  4. ncbi request reprint Increased myocardial contractility and enhanced exercise function in transgenic mice overexpressing either adenylyl cyclase 5 or 8
    Giovanni Esposito
    Division of Cardiology, University Federico II of Naples, Via Pansini 5, 80131 Naples, Italy
    Basic Res Cardiol 103:22-30. 2008
  5. doi request reprint Endovascular repair for isolated iliac artery aneurysms: case report and review of the current literature
    Giovanni Esposito
    Division of Cardiology, Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Naples, Italy
    J Cardiovasc Med (Hagerstown) 10:861-5. 2009
  6. doi request reprint Induction of mitogen-activated protein kinases is proportional to the amount of pressure overload
    Giovanni Esposito
    Division of Cardiology, Federico II University, Via Pansini 5, 80131 Naples, Italy
    Hypertension 55:137-43. 2010
  7. doi request reprint Cardiovascular effects of treadmill exercise in physiological and pathological preclinical settings
    Cinzia Perrino
    Div of Cardiology, Federico II Univ, Via Pansini 5, 80131, Naples, Italy
    Am J Physiol Heart Circ Physiol 300:H1983-9. 2011
  8. doi request reprint EGFR trans-activation by urotensin II receptor is mediated by β-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy
    Giovanni Esposito
    Division of Cardiology, Federico II University of Naples, Via Pansini 5, Naples, Italy
    Basic Res Cardiol 106:577-89. 2011
  9. doi request reprint The extent of irreversible myocardial damage and the potential for left ventricular repair after primary percutaneous coronary intervention
    Giovanni Esposito
    Division of Cardiology, Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy
    Am Heart J 160:S4-10. 2010
  10. doi request reprint MGUard versus bAre-metal stents plus manual thRombectomy in ST-elevation myocarDial infarction pAtieNts-(GUARDIAN) trial: study design and rationale
    Salvatore Cassese
    Department of Clinical Medicine, Cardiovascular Sciences and Immunology, Federico II University, Naples, Italy
    Catheter Cardiovasc Interv 79:1118-26. 2012

Detail Information

Publications75

  1. ncbi request reprint Contemporary use and results of intra-aortic balloon pump counterpulsation
    Giuseppe Gargiulo
    Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy
    Minerva Cardioangiol 64:84-91. 2016
    ..This review will describe the role of IABP in the modern clinical practice. ..
  2. doi request reprint Dermcidin: a skeletal muscle myokine modulating cardiomyocyte survival and infarct size after coronary artery ligation
    Giovanni Esposito
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Via Pansini 5, Naples 80131, Italy
    Cardiovasc Res 107:431-41. 2015
    ..However, the molecular mechanisms underlying these effects are currently unknown...
  3. ncbi request reprint Cardiac side effects of chemotherapy: state of art and strategies for a correct management
    Cinzia Perrino
    Division of Cardiology, Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Via Pansini 5, 80131 Naples, Italy
    Curr Vasc Pharmacol 12:106-16. 2014
    ..The purpose of this review is to discuss the clinical features of cardiotoxicity, its molecular basis and novel possible strategies to reduce the likelihood of serious cardiac complications. ..
  4. ncbi request reprint Increased myocardial contractility and enhanced exercise function in transgenic mice overexpressing either adenylyl cyclase 5 or 8
    Giovanni Esposito
    Division of Cardiology, University Federico II of Naples, Via Pansini 5, 80131 Naples, Italy
    Basic Res Cardiol 103:22-30. 2008
    ..Whether AC overexpression affects intrinsic cardiac contractility in an isoform-specific fashion determining a change in exercise capacity is currently unknown...
  5. doi request reprint Endovascular repair for isolated iliac artery aneurysms: case report and review of the current literature
    Giovanni Esposito
    Division of Cardiology, Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Naples, Italy
    J Cardiovasc Med (Hagerstown) 10:861-5. 2009
    ....
  6. doi request reprint Induction of mitogen-activated protein kinases is proportional to the amount of pressure overload
    Giovanni Esposito
    Division of Cardiology, Federico II University, Via Pansini 5, 80131 Naples, Italy
    Hypertension 55:137-43. 2010
    ..These results suggest that MAPKs are sensors of pressure overload and that extracellular signal-regulated kinase activation in WBCs might be used as a novel surrogate biomarker of uncontrolled human hypertension...
  7. doi request reprint Cardiovascular effects of treadmill exercise in physiological and pathological preclinical settings
    Cinzia Perrino
    Div of Cardiology, Federico II Univ, Via Pansini 5, 80131, Naples, Italy
    Am J Physiol Heart Circ Physiol 300:H1983-9. 2011
    ..Moreover, we discuss how treadmill exercise can be used to perform physiological testing in mouse models of disease and to enlighten the role of specific signaling pathways on cardiac function...
  8. doi request reprint EGFR trans-activation by urotensin II receptor is mediated by β-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy
    Giovanni Esposito
    Division of Cardiology, Federico II University of Naples, Via Pansini 5, Naples, Italy
    Basic Res Cardiol 106:577-89. 2011
    ..Our data show, for the first time in vivo, a new UTR signalling pathway which is mediated by EGFR trans-activation, dependent by β-arrestin 1/2, promoting cell survival and cardioprotection...
  9. doi request reprint The extent of irreversible myocardial damage and the potential for left ventricular repair after primary percutaneous coronary intervention
    Giovanni Esposito
    Division of Cardiology, Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy
    Am Heart J 160:S4-10. 2010
    ..Proposed therapeutic strategies to repair irreversible myocardial damage in patients treated with primary PCI are also considered, with particular focus on the value of stem cell therapy in this specific setting...
  10. doi request reprint MGUard versus bAre-metal stents plus manual thRombectomy in ST-elevation myocarDial infarction pAtieNts-(GUARDIAN) trial: study design and rationale
    Salvatore Cassese
    Department of Clinical Medicine, Cardiovascular Sciences and Immunology, Federico II University, Naples, Italy
    Catheter Cardiovasc Interv 79:1118-26. 2012
    ....
  11. ncbi request reprint AngioJet rheolytic thrombectomy for acute superficial femoral artery stent or femoropopliteal by-pass thrombosis
    Francesco Borgia
    Division of Cardiology, Federico II University of Naples, Italy
    Monaldi Arch Chest Dis 74:76-81. 2010
    ..Taken together, these cases suggest that AngioJet rheolytic thrombectomy might represent a novel effective strategy in the percutaneous treatment of stent or graft thrombosis determining ALI...
  12. doi request reprint Effects of successful percutaneous lower extremity revascularization on cardiovascular outcome in patients with peripheral arterial disease
    Giuseppe Giugliano
    Division of Cardiology, Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Naples, Italy
    Int J Cardiol 167:2566-71. 2013
    ..Endovascular revascularization of LE-PAD improves walking performance and quality of life. In the present study, we determined whether successful lower limbs revascularization also impacts cardiovascular outcome in LE-PAD patients...
  13. pmc Endovascular treatment of lower extremity arteries is associated with an improved outcome in diabetic patients affected by intermittent claudication
    Giuseppe Giugliano
    Department of Clinical Medicine and Cardiovascular and Immunological Sciences, Federico II University, Via Pansini 5, 80131 Naples, Italy
    BMC Surg 12:S19. 2012
    ....
  14. doi request reprint Prevalence and severity of asymptomatic coronary and carotid artery disease in patients with lower limbs arterial disease
    Fabio Marsico
    Department of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini, 5, I 80131 Naples, Italy
    Atherosclerosis 228:386-9. 2013
    ..The purpose of this study was to evaluate the prevalence and severity of CAD and CVD in patients with LLAD of the lower extremities...
  15. doi request reprint Balancing hemorrhagic and thrombotic complications in a patient with a very late paclitaxel-eluting stent thrombosis: a clinical case report
    Giovanni Esposito
    Division of Cardiology, Federico II University, Naples, Italy
    J Cardiovasc Med (Hagerstown) 12:366-9. 2011
    ..Here, we report a case of very late stent thrombosis (VLST) experienced 1462 days after DES deployment in a patient with challenging clinical status, requiring counterbalancing hemorrhagic and thrombotic risk factors...
  16. pmc Genetic deletion of uncoupling protein 3 exaggerates apoptotic cell death in the ischemic heart leading to heart failure
    Cinzia Perrino
    Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    J Am Heart Assoc 2:e000086. 2013
    ..In this study, we investigated the effects of ucp3 genetic deletion on mitochondrial function and cell survival under low oxygen conditions in vitro and in vivo...
  17. pmc Abdominal aortic aneurysm in patients affected by intermittent claudication: prevalence and clinical predictors
    Giuseppe Giugliano
    Department of Clinical Medicine and Cardiovascular and Immunological Sciences, Federico II University, Via Pansini 5, 80131 Naples, Italy
    BMC Surg 12:S17. 2012
    ..We aimed this study at assessing the prevalence and the clinical predictors of the presence of AAA in a homogeneous cohort of LE-PAD patients affected by intermittent claudication...
  18. doi request reprint Multicentre experience with MGuard net protective stent in ST-elevation myocardial infarction: safety, feasibility, and impact on myocardial reperfusion
    Federico Piscione
    Department of Clinical Medicine, Cardiovascular Sciences and Immunology, Federico II University, Naples, Italy
    Catheter Cardiovasc Interv 75:715-21. 2010
    ....
  19. doi request reprint A new approach to percutaneous coronary revascularization in patients requiring undeferrable non-cardiac surgery
    Federico Piscione
    Department of Clinical Medicine, Cardiovascular Science and Immunology, Federico II University, Naples, Italy
    Int J Cardiol 146:399-403. 2011
    ..We performed a pilot study of dual antiplatelet therapy discontinuation followed by major non-cardiac surgery and endovascular aortic repair early after successful endothelial-progenitor cell-capture coronary stent deployment...
  20. doi request reprint A meta-analysis of the impact of pre-existing and new-onset atrial fibrillation on clinical outcomes in patients undergoing transcatheter aortic valve implantation
    Anna Sannino
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    EuroIntervention 12:e1047-e1056. 2016
    ..Therefore, the aim of this meta-analysis was to compare the short- and long-term clinical outcomes of patients undergoing TAVI with and without pre-existing and new-onset AF...
  21. doi request reprint Aortic and Mitral Calcification Is Marker of Significant Carotid and Limb Atherosclerosis in Patients with First Acute Coronary Syndrome
    Anna Sannino
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    Echocardiography 32:1771-7. 2015
    ....
  22. doi request reprint Cerebral embolic lesions detected with diffusion-weighted magnetic resonance imaging following carotid artery stenting: a meta-analysis of 8 studies comparing filter cerebral protection and proximal balloon occlusion
    Eugenio Stabile
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    JACC Cardiovasc Interv 7:1177-83. 2014
    ....
  23. pmc Genetic deletion in uncoupling protein 3 augments 18F-fluorodeoxyglucose cardiac uptake in the ischemic heart
    Sara Gargiulo
    Department of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131 Naples, Italy
    BMC Cardiovasc Disord 14:98. 2014
    ....
  24. doi request reprint Meta-analysis of mortality outcomes and mitral regurgitation evolution in 4,839 patients having transcatheter aortic valve implantation for severe aortic stenosis
    Anna Sannino
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    Am J Cardiol 114:875-82. 2014
    ..In addition, in the same group of patients, a trend toward a reduction in MR severity was observed. Whether the decrease in MR severity affects mortality after TAVI remains to be defined...
  25. ncbi request reprint Endovascular treatment of carotid artery stenosis: evidences from randomized controlled trials and actual indications
    Federica Ilardi
    Division of Cardiology, Federico II University of Naples, Italy
    Monaldi Arch Chest Dis 76:183-91. 2011
    ..Purpose of this review is to discuss the most recent clinical evidences concerning the treatment of carotid artery stenosis, with a special focus on the endovascular treatment...
  26. pmc Ankle/brachial index to everyone
    Giuseppe Giugliano
    Department of Clinical Medicine and Cardiovascular and Immunological Sciences, Federico II University, Via Pansini 5, 80131 Naples, Italy
    BMC Surg 12:S18. 2012
    ..In the last years significant attention has been paid in identifying markers of subclinical atherosclerosis or of increased cardiovascular risk...
  27. pmc Use of statins in lower extremity artery disease: a review
    Giuseppe Gargiulo
    Department of Clinical Medicine and Cardiovascular and Immunology Sciences, Federico II University, Via Pansini 5, 80131 Naples, Italy
    BMC Surg 12:S15. 2012
    ..Lower extremity artery disease (LE-PAD) is one of the most common manifestations of atherosclerosis, particularly in elderly patients, and it is related to a high cardiovascular risk...
  28. doi request reprint Meta-Analysis of Effect of Body Mass Index on Outcomes After Transcatheter Aortic Valve Implantation
    Anna Sannino
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy Division of Cardiology, Baylor University Medical Center, Dallas, Texas
    Am J Cardiol 119:308-316. 2017
    ..In conclusion, a low BMI is linked to a significantly worse prognosis after TAVI. Therefore, BMI represents an important and handily tool that might be used in the risk prediction of patients to be addressed for TAVI...
  29. doi request reprint Impact of postoperative acute kidney injury on clinical outcomes after transcatheter aortic valve implantation: A meta-analysis of 5,971 patients
    Giuseppe Gargiulo
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    Catheter Cardiovasc Interv 86:518-27. 2015
    ..Therefore, we conducted a meta-analysis on the impact of AKI on clinical outcomes after TAVI...
  30. doi request reprint Non-invasive vulnerable plaque imaging: how do we know that treatment works?
    Anna Sannino
    Cardiology, Department of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy
    Eur Heart J Cardiovasc Imaging 15:1194-202. 2014
    ..This review summarizes the currently available non-invasive methods to identify vulnerable plaques and to evaluate the effects of the current cardiovascular treatments on plaque evolution. ..
  31. doi request reprint Increased mortality after transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis and low ejection fraction: a meta-analysis of 6898 patients
    Anna Sannino
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    Int J Cardiol 176:32-9. 2014
    ....
  32. pmc The role of atherectomy in the treatment of lower extremity peripheral artery disease
    Anna Franzone
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Via S, Pansini 5, 80131 Naples, Italy
    BMC Surg 12:S13. 2012
    ..Despite the significant development of percutaneous revascularization strategies, over the past decade, LE-PAD still represents a unique challenge for interventional cardiologists and vascular surgeons...
  33. ncbi request reprint Development of Left Ventricular Hypertrophy in Treated Hypertensive Outpatients: The Campania Salute Network
    Raffaele Izzo
    From the Hypertension Research Center R I, M A L, E S, M T L, G C, G E, E B, N D L, B T, G d S, Department of Translational Medical Sciences R I, G C, N D L, G d S, and Department of Advanced Biomedical Sciences M A L, E S, G E, E B, B T, Federico II University, Naples, Italy and Department of Clinical Science, University of Bergen, Norway M T L
    Hypertension 69:136-142. 2017
    ..After adjusting for confounders, risk of incident LVH is particular relevant among women and is further increased by the presence of obesity...
  34. doi request reprint Unexpected preserved brain perfusion imaging despite severe and diffuse atherosclerosis of supra-aortic trunks
    Giuseppe Gargiulo
    Division of Cardiology, Department of Clinical Medicine, Cardiovascular Sciences and Immunology, Federico II University, Naples, Italy
    Cardiovasc J Afr 24:e12-4. 2013
    ..An accurate imaging analysis together with clinical features allowed us to decide on a strategy based on optimal medical therapy and careful clinical monitoring...
  35. doi request reprint Development of new atherosclerotic plaque in hypertensive patients: an observational registry study from the Campania-Salute network
    Raffaele Izzo
    aHypertension Research Center bDepartment of Translational Medical Sciences cDepartment of Advanced Biomedical Sciences dDepartment of Neurosciences, Federico II University, Naples, Italy
    J Hypertens 33:2471-6. 2015
    ..Carotid atherosclerotic plaques (CAPs) can develop despite appropriate antihypertensive therapy. In this observational study, we assessed characteristics associated with risk of incident CAP in a large hypertensive registry...
  36. doi request reprint Prothymosin alpha protects cardiomyocytes against ischemia-induced apoptosis via preservation of Akt activation
    Alessandro Cannavo
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University of Naples, Via Pansini, 5, 80131, Naples, Italy
    Apoptosis 18:1252-61. 2013
    ..The present study provides for the first time the demonstration that PTα offers cardioprotection against ischemic injury by an Akt-dependent mechanism. ..
  37. ncbi request reprint Unrestricted use of endeavor resolute zotarolimus-eluting stent in daily clinical practice: a prospective registry
    Gennaro Galasso
    Department of Clinical Medicine, Cardiovascular Sciences and Immunology, Federico II University, Via S Pansini, 5 80131 Naples, Italy
    J Invasive Cardiol 24:251-5. 2012
    ..To evaluate the safety and efficacy of unrestricted Endeavor Resolute zotarolimus-eluting stent (ZES) use. Furthermore, we sought to evaluate clinical outcomes associated with on- and off-label use of Resolute ZES...
  38. doi request reprint Complementary therapeutic effects of dual delivery of insulin-like growth factor-1 and vascular endothelial growth factor by gelatin microspheres in experimental heart failure
    Antonio Cittadini
    Department of Internal Medicine and Cardiovascular Sciences, University Federico II, Via Sergio Pansini 5, Naples, Italy
    Eur J Heart Fail 13:1264-74. 2011
    ..Our aim was to investigate the effects of sequential release of vascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1) from biodegradable gelatin microspheres in experimental heart failure...
  39. pmc Effects of a new combination of nutraceuticals with Morus alba on lipid profile, insulin sensitivity and endotelial function in dyslipidemic subjects. A cross-over, randomized, double-blind trial
    Valentina Trimarco
    Department of Neurosciences, Federico II University, Naples, Italy
    High Blood Press Cardiovasc Prev 22:149-54. 2015
    ..Nutraceuticals (NUT) are forms of compounds with biological activity commonly used to improve health in dosage largely exceeding those obtainable in food...
  40. doi request reprint Femoral plaque echogenicity and cardiovascular risk in claudicants
    Vittorio Schiano
    Division of Cardiology, Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University of Naples Federico II, Naples, Italy
    JACC Cardiovasc Imaging 5:348-57. 2012
    ..The present study was designed to verify whether the evaluation of femoral plaque echogenicity might be a useful tool for cardiovascular risk assessment in patients affected by lower extremity peripheral arterial disease...
  41. doi request reprint Cardiovascular ultrasound exploration contributes to predict incident atrial fibrillation in arterial hypertension: the Campania Salute Network
    Maria Angela Losi
    Hypertension Research Center, Federico II University, Naples, Italy Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    Int J Cardiol 199:290-5. 2015
    ..We designed an observational, longitudinal, retrospective study to predict risk of incident AF by combination of CV risk profile, target organ damage and therapy in hypertensive patients...
  42. doi request reprint Prevalence and severity of asymptomatic coronary and carotid artery disease in patients with abdominal aortic aneurysm
    Fabio Marsico
    Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy
    Angiology 66:360-4. 2015
    ..Severe asymptomatic CAD is prevalent in AAA, and 31% of patients fulfill indications for coronary revascularization. ..
  43. doi request reprint Reperfusion correlates and clinical outcomes of right ventricular dysfunction in patients with inferior ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention
    Raffaele Piccolo
    Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    Am J Cardiol 114:243-9. 2014
    ..In conclusion, in patients with inferior STEMI undergoing coronary revascularization, RV dysfunction is associated with a worse long-term prognosis. Postprocedural TIMI flow grade may be a useful tool to predict RV dysfunction...
  44. doi request reprint Coronary angioplasty with stenting for acute coronary syndrome in patients with isolated single coronary artery: a report of two cases
    Fulvio Furbatto
    Division of Cardiology, Federico II University, Naples, Italy
    J Cardiovasc Med (Hagerstown) 10:550-3. 2009
    ..We report two cases of isolated single coronary arteries who underwent successful coronary angioplasty and stenting for acute coronary syndrome...
  45. doi request reprint Abciximab in elderly with acute coronary syndrome invasively treated: effect on outcome
    Gennaro Galasso
    Division of Cardiology, Federico II University, Naples, Italy
    Int J Cardiol 130:380-5. 2008
    ....
  46. doi request reprint Impact of Sex on 2-Year Clinical Outcomes in Patients Treated With 6-Month or 24-Month Dual-Antiplatelet Therapy Duration: A Pre-Specified Analysis From the PRODIGY Trial
    Giuseppe Gargiulo
    Department of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy
    JACC Cardiovasc Interv 9:1780-9. 2016
    ..The aim of this study was to assess the impact of sex on 2-year outcomes after percutaneous coronary intervention (PCI) in patients randomly allocated to 24-month versus 6-month dual-antiplatelet therapy (DAPT)...
  47. pmc Identification of the main determinants of abdominal aorta size: a screening by Pocket Size Imaging Device
    Roberta Esposito
    Department of Advanced Biomedical Sciences, Division of Cardiology, Federico II University Hospital, Naples, Italy
    Cardiovasc Ultrasound 15:2. 2017
    ..Our aim was to assess the impact of demographics and cardiovascular (CV) risk factors on AA size by using PSID in an outpatient screening...
  48. pmc New cerebral lesions at magnetic resonance imaging after carotid artery stenting versus endarterectomy: an updated meta-analysis
    Giuseppe Gargiulo
    Division of Cardiology Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    PLoS ONE 10:e0129209. 2015
    ..Therefore, we conducted an updated meta-analysis on the occurrence of post-procedural new DWI lesions after CAS versus CEA...
  49. doi request reprint Moderate and severe preoperative chronic kidney disease worsen clinical outcomes after transcatheter aortic valve implantation: meta-analysis of 4992 patients
    Giuseppe Gargiulo
    From the Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy G G, A s, C P, E S, B T, G E Division of Cardiology, Ferrarotto Hospital, University of Catania, Catania, Italy D C, P C, C T and Excellence Through Newest Advances ETNA Foundation, Catania, Italy C T
    Circ Cardiovasc Interv 8:e002220. 2015
    ..Therefore, we conducted a meta-analysis on the impact of CKD on outcomes after transcatheter aortic valve implantation...
  50. doi request reprint Relationship between changes in platelet reactivity and ischemic events following percutaneous coronary intervention: a meta-regression analysis of 30 randomized trials
    Raffaele Piccolo
    Department of Advanced Biomedical Sciences, Federico II University, Via S Pansini 5, 80131 Naples, Italy
    Atherosclerosis 234:176-84. 2014
    ..However, whether reducing platelet reactivity can lead to a lower incidence of ischemic events after PCI is still controversial. Therefore, we sought to investigate this issue by a meta-regression analysis of randomized trials...
  51. ncbi request reprint Statins and the elderly: recent evidence and current indications
    Gabriele Giacomo Schiattarella
    Department of Clinical Medicine and Cardiovascular and Immunology Sciences, University of Naples Federico II, Via Pansini 5, 80131 Napoli, Italy
    Aging Clin Exp Res 24:47-55. 2012
    ..Also discussed is the latest evidence regarding the putative protective effects of statins on senile dementia and the relationship between statin treatment and cancer...
  52. doi request reprint Tirofiban administration and percutaneous coronary intervention with stenting of saphenous vein graft thrombosis
    Claudia D'andrea
    Department of Clinical Medicine, Cardiovascular Sciences and Immunology, Federico II University, Naples, Italy
    J Cardiovasc Med (Hagerstown) 10:875-8. 2009
    ..Further studies are needed to further expand our findings...
  53. pmc Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis
    Gabriele Giacomo Schiattarella
    Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    PLoS ONE 11:e0154076. 2016
    ..Thus, mitochondrial AKAPs might represent important players in the development of post-ischemic cardiac remodeling and novel therapeutic targets. ..
  54. doi request reprint Meta-analysis of randomized trials comparing the effectiveness of different strategies for the treatment of drug-eluting stent restenosis
    Raffaele Piccolo
    Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    Am J Cardiol 114:1339-46. 2014
    ..However, PEB had greater angiographic efficacy and therefore should be considered the new benchmark comparator in the treatment of DES restenosis. The use of BA should be discouraged in patients with DES restenosis. ..
  55. pmc Transradial versus transfemoral approach in patients undergoing percutaneous coronary intervention for acute coronary syndrome. A meta-analysis and trial sequential analysis of randomized controlled trials
    Raffaele Piccolo
    Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    PLoS ONE 9:e96127. 2014
    ..A meta-analysis, meta-regression and trial sequential analysis of safety and efficacy of TRA in ACS setting was performed...
  56. doi request reprint Endothelial dysfunction in type 2 diabetic patients with normal coronary arteries: a digital reactive hyperemia study
    Paola Gargiulo
    Department of Internal Medicine, Cardiovascular and Immunological Sciences, Federico II University, Naples, Italy
    Int J Cardiol 165:67-71. 2013
    ..To assess endothelial function (EF) in type 2 diabetic patients with angiographically normal coronaries compared to diabetic patients with obstructive coronary artery disease (CAD) and to non-diabetic patients, with and without CAD...
  57. ncbi request reprint Exercise training and beta-blocker treatment ameliorate age-dependent impairment of beta-adrenergic receptor signaling and enhance cardiac responsiveness to adrenergic stimulation
    Dario Leosco
    Department of Internal Medicine, Cardiovascular Sciences and Immunology, University Federico II, Via Pansini 5, Edificio 2, 80131 Naples, Italy
    Am J Physiol Heart Circ Physiol 293:H1596-603. 2007
    ..In conclusion, we demonstrate for the first time that exercise and beta-AR blockade can similarly ameliorate beta-AR signaling in the aged heart, leading to improved beta-AR responsiveness and corresponding LV inotropic reserve...
  58. ncbi request reprint Rheolytic thrombectomy during percutaneous coronary intervention improves long-term outcome in high-risk patients with acute myocardial infarction
    Salvatore De Rosa
    Division of Cardiology, University of Naples Federico II, Naples, Italy
    J Interv Cardiol 20:292-8. 2007
    ....
  59. doi request reprint AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress
    Cinzia Perrino
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Naples 80131, Italy
    Cardiovasc Res 88:101-10. 2010
    ..The aim of the present study was to determine the function and the role of the scaffold protein AKAP121, tethering cAMP dependent protein kinase A to the outer wall of mitochondria, in neonatal ventricular myocytes and the heart...
  60. doi request reprint Peripheral drug-eluting technology
    Anna Franzone
    Division of Cardiology, Department of Advanced Biomedical Sciences, University of Napoli Federico II, Via S Pansini 5, Napoli 80131, Italy
    Cardiol Clin 33:151-62. 2015
    ..Finally, ongoing studies and potential novel applications of drug-eluting technologies in other vascular beds are mentioned. ..
  61. doi request reprint Drug-eluting balloons for the treatment of the superficial femoral artery in-stent restenosis: 2-year follow-up
    Vittorio Virga
    Division of Cardiology, Clinical and Experimental Department of Medicine, University of Messina, Messina, Italy
    JACC Cardiovasc Interv 7:411-5. 2014
    ..The aim of this prospective registry was to evaluate the safety and efficacy at 2-year follow-up of the use of drug-eluting balloons (DEBs) for the treatment of superficial femoral artery (SFA) in-stent restenosis (ISR)...
  62. doi request reprint FFR prediction model based on conventional quantitative coronary angiography and the amount of myocardium subtended by an intermediate coronary artery stenosis
    Luigi Di Serafino
    Division of Cardiology, Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy Division of Cardiology, P O Di Venere, 70123 Bari, Italy Electronic address
    Int J Cardiol 223:340-344. 2016
    ..We aimed this study in order to evaluate the accuracy of the "Angiography-DeriveD hEmoDynamic index" (ADDED index) to predict the FFR as compared with the iFR...
  63. pmc Diabetes does not impact the diagnostic performance of contrast-based fractional flow reserve: insights from the CONTRAST study
    Giuseppe Gargiulo
    Department of Advanced Biomedical Sciences, University of Naples Frederico II, Naples, Italy
    Cardiovasc Diabetol 16:7. 2017
    ..Adenosine-free coronary pressure wire metrics have been proposed to test the functional significance of coronary artery lesions, but it is unexplored whether their diagnostic performance might be altered in patients with diabetes...
  64. doi request reprint Percutaneous sympathectomy of the renal arteries: the OneShot Renal Denervation System is not associated with significant vessel wall injury
    Eugenio Stabile
    Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
    EuroIntervention 9:694-9. 2013
    ..The OneShot System (Covidien, San Jose, CA, USA) is an irrigated radiofrequency balloon designed to reduce vessel heating and injury during RADN...
  65. doi request reprint Adipokines, vascular wall, and cardiovascular disease: a focused overview of the role of adipokines in the pathophysiology of cardiovascular disease
    Fabio Maresca
    Department of Advanced Biomedical Sciences, Division of Cardiology, University of Naples, Naples, Italy
    Angiology 66:8-24. 2015
    ..We consider the main adipokines, focusing on their effects on the vascular wall and analyzing their role in CV pathophysiology. ..
  66. pmc Epigenetic switch at atp2a2 and myh7 gene promoters in pressure overload-induced heart failure
    Tiziana Angrisano
    Department of Molecular Medicine and Medical Biotechnology, Federico II University, Naples, Italy Department of Biology, Federico II University, Naples, Italy
    PLoS ONE 9:e106024. 2014
    ....
  67. doi request reprint Surgical resection of carotid body paragangliomas: 10 years of experience
    Bruno Amato
    Department of General, Geriatric, Oncologic Surgery and Advanced Technologies, University of Naples Federico II, Naples, Italy
    Am J Surg 207:293-8. 2014
    ..The objective of this study was to conduct a review of the surgical management of CBTs...
  68. doi request reprint Reproducibility and accuracy of non-invasive measurement of infarct size in mice with high-resolution PET/CT
    Adelaide Greco
    Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy
    J Nucl Cardiol 19:492-9. 2012
    ....
  69. pmc Percutaneous treatment of patients with heart diseases: selection, guidance and follow-up. A review
    Carla Contaldi
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy
    Cardiovasc Ultrasound 10:16. 2012
    ....
  70. doi request reprint Impact of proton pump inhibitors on clinical outcomes in patients treated with a 6- or 24-month dual-antiplatelet therapy duration: Insights from the PROlonging Dual-antiplatelet treatment after Grading stent-induced Intimal hyperplasia studY trial
    Giuseppe Gargiulo
    Department of Cardiology, Bern University Hospital, Bern, Switzerland Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy
    Am Heart J 174:95-102. 2016
    ..We assessed the association between PPI use and clinical outcomes for patients treated with percutaneous coronary intervention (PCI) and dual-antiplatelet therapy (DAPT) with clopidogrel plus aspirin...
  71. pmc The Murine Model of Mucopolysaccharidosis IIIB Develops Cardiopathies over Time Leading to Heart Failure
    Gabriele Giacomo Schiattarella
    Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy
    PLoS ONE 10:e0131662. 2015
    ..Overall, our findings demonstrate that NAGLU(-/-) mice develop heart disease, valvular abnormalities and cardiac failure associated with an impaired lysosomal autophagic flux...
  72. pmc Subclinical myocardial dysfunction and cardiac autonomic dysregulation are closely associated in obese children and adolescents: the potential role of insulin resistance
    Domenico Cozzolino
    Department of Internal Medicine, Second University of Naples, Naples, Italy
    PLoS ONE 10:e0123916. 2015
    ....
  73. doi request reprint Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease
    Caterina Marciano
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University Federico II, Napoli, Italy
    Eur J Nucl Med Mol Imaging 39:1199-206. 2012
    ..We assessed the impact of type 2 diabetes, in the presence of other major cardiovascular risk factors, on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease (CAD)...
  74. ncbi request reprint Long abdominal aortic stenosis: a rare presentation of Takayasu arteritis treated with percutaneous stent implantation
    Pasquale Perrone-Filardi
    Department of Internal Medicine, Cardiovascular and Immunological Sciences, Federico II University, Naples, Italy
    J Thorac Cardiovasc Surg 133:1647-8. 2007