Rosario Cuomo

Summary

Affiliation: Federico II University
Country: Italy

Publications

  1. doi request reprint Carbonated beverages and gastrointestinal system: between myth and reality
    R Cuomo
    Gastroenterology Unit, Department of Clinical and Experimental Medicine, University of Naples Federico II, Via Sergio Pansini 5, 80131 Napoli, Italy
    Nutr Metab Cardiovasc Dis 19:683-9. 2009
  2. doi request reprint Alcoholic beverages and carbonated soft drinks: consumption and gastrointestinal cancer risks
    Rosario Cuomo
    Department of Clinical and Experimental Medicine, Hospital School of Medicine, Federico II University, Via S Pansini 5, Building No 6, 80131, Naples, Italy
    Cancer Treat Res 159:97-120. 2014
  3. pmc The antiprotozoal drug pentamidine ameliorates experimentally induced acute colitis in mice
    Giuseppe Esposito
    Department of Physiology and Pharmacology Vittorio Erspamer, University Sapienza of Rome, P le Aldo Moro 5, 00185 Rome, Italy
    J Neuroinflammation 9:277. 2012
  4. ncbi request reprint Gastrointestinal regulation of food intake: do gut motility, enteric nerves and entero-hormones play together?
    R Cuomo
    Department of Clinical and Experimental Medicine, University of Naples Federico II, Naples, Italy
    Minerva Endocrinol 36:281-93. 2011
  5. doi request reprint Sweetened carbonated drinks do not alter upper digestive tract physiology in healthy subjects
    R Cuomo
    Gastroenterology Unit, Department of Clinical and Experimental Medicine, University of Naples, Naples, Italy
    Neurogastroenterol Motil 20:780-9. 2008
  6. ncbi request reprint Can the analysis of GORD-related sleep disturbances help the clinician to better manage the disease?
    R Cuomo
    Gastroenterological Unit, Department of Clinical and Experimental Medicine, University of Naples Federico II, Naples, Italy
    Neurogastroenterol Motil 19:701-3. 2007
  7. ncbi request reprint Almost all irritable bowel syndromes are post-infectious and respond to probiotics: consensus issues
    Rosario Cuomo
    Gastroenterological Unit, Department of Clinical and Experimental Medicine, University of Naples Federico II, Naples, Italy
    Dig Dis 25:241-4. 2007
  8. pmc The role of a pre-load beverage on gastric volume and food intake: comparison between non-caloric carbonated and non-carbonated beverage
    Rosario Cuomo
    Gastroenterology Unit, Department of Clinical and Experimental Medicine, University of Naples, Italy
    Nutr J 10:114. 2011
  9. ncbi request reprint Oesophageal acid exposure and altered neurocardiac function in patients with GERD and idiopathic cardiac dysrhythmias
    R Cuomo
    Department of Clinical and Experimental Medicine, Gastroenterology, University Federico II, Naples, Italy
    Aliment Pharmacol Ther 24:361-70. 2006
  10. pmc S100B protein in the gut: the evidence for enteroglial-sustained intestinal inflammation
    Carla Cirillo
    Department of Clinical and Experimental Medicine, University of Naples Federico II, Naples, Italy
    World J Gastroenterol 17:1261-6. 2011

Collaborators

Detail Information

Publications46

  1. doi request reprint Carbonated beverages and gastrointestinal system: between myth and reality
    R Cuomo
    Gastroenterology Unit, Department of Clinical and Experimental Medicine, University of Naples Federico II, Via Sergio Pansini 5, 80131 Napoli, Italy
    Nutr Metab Cardiovasc Dis 19:683-9. 2009
    ..More epidemiological and mechanistic studies are also needed to evaluate the possible drawbacks of their consumption in terms of risk of tooth erosion and gastric distress...
  2. doi request reprint Alcoholic beverages and carbonated soft drinks: consumption and gastrointestinal cancer risks
    Rosario Cuomo
    Department of Clinical and Experimental Medicine, Hospital School of Medicine, Federico II University, Via S Pansini 5, Building No 6, 80131, Naples, Italy
    Cancer Treat Res 159:97-120. 2014
    ..However, several surveys have failed to show any associations between CSDs and esophageal, gastric, or colon cancers. On the other hand, a slight correlation between risk of pancreatic cancer and CSD consumption has been found. ..
  3. pmc The antiprotozoal drug pentamidine ameliorates experimentally induced acute colitis in mice
    Giuseppe Esposito
    Department of Physiology and Pharmacology Vittorio Erspamer, University Sapienza of Rome, P le Aldo Moro 5, 00185 Rome, Italy
    J Neuroinflammation 9:277. 2012
    ..The antiprotozoal drug pentamidine directly blocks S100B activity. We aimed to investigate the effect of pentamidine on intestinal inflammation using an animal model of dextran sodium sulphate (DSS)-induced acute colitis...
  4. ncbi request reprint Gastrointestinal regulation of food intake: do gut motility, enteric nerves and entero-hormones play together?
    R Cuomo
    Department of Clinical and Experimental Medicine, University of Naples Federico II, Naples, Italy
    Minerva Endocrinol 36:281-93. 2011
    ..The close linkage among gastrointestinal hormones, the gut and the central nervous systems appears very intriguing and has induced the development of a new field of research: the gastroendocrinology...
  5. doi request reprint Sweetened carbonated drinks do not alter upper digestive tract physiology in healthy subjects
    R Cuomo
    Gastroenterology Unit, Department of Clinical and Experimental Medicine, University of Naples, Naples, Italy
    Neurogastroenterol Motil 20:780-9. 2008
    ..This study shows that 300 mL of sweetened carbonated beverage with different levels of carbonation or a commercial soft drink do not modify the physiology of the upper digestive tract...
  6. ncbi request reprint Can the analysis of GORD-related sleep disturbances help the clinician to better manage the disease?
    R Cuomo
    Gastroenterological Unit, Department of Clinical and Experimental Medicine, University of Naples Federico II, Naples, Italy
    Neurogastroenterol Motil 19:701-3. 2007
  7. ncbi request reprint Almost all irritable bowel syndromes are post-infectious and respond to probiotics: consensus issues
    Rosario Cuomo
    Gastroenterological Unit, Department of Clinical and Experimental Medicine, University of Naples Federico II, Naples, Italy
    Dig Dis 25:241-4. 2007
    ..Here, advances in the pathophysiology supporting the post-infectious hypothesis are considered. In addition, the current role of probiotics in the management of Pi-IBS is discussed...
  8. pmc The role of a pre-load beverage on gastric volume and food intake: comparison between non-caloric carbonated and non-carbonated beverage
    Rosario Cuomo
    Gastroenterology Unit, Department of Clinical and Experimental Medicine, University of Naples, Italy
    Nutr J 10:114. 2011
    ....
  9. ncbi request reprint Oesophageal acid exposure and altered neurocardiac function in patients with GERD and idiopathic cardiac dysrhythmias
    R Cuomo
    Department of Clinical and Experimental Medicine, Gastroenterology, University Federico II, Naples, Italy
    Aliment Pharmacol Ther 24:361-70. 2006
    ..Oesophageal sensory stimuli alter neurocardiac function through autonomic reflexes...
  10. pmc S100B protein in the gut: the evidence for enteroglial-sustained intestinal inflammation
    Carla Cirillo
    Department of Clinical and Experimental Medicine, University of Naples Federico II, Naples, Italy
    World J Gastroenterol 17:1261-6. 2011
    ..In this review we describe the major features of EGCs and S100B protein occurring in intestinal inflammation deriving from such...
  11. doi request reprint Palmitoylethanolamide Exerts Antiproliferative Effect and Downregulates VEGF Signaling in Caco-2 Human Colon Carcinoma Cell Line Through a Selective PPAR-α-Dependent Inhibition of Akt/mTOR Pathway
    Giovanni Sarnelli
    Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy
    Phytother Res 30:963-70. 2016
    ..If supported by in vivo models, our data pave the way to PEA co-administration to the current chemotherapeutic regimens for colon carcinoma. Copyright © 2016 John Wiley & Sons, Ltd. ..
  12. pmc Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis
    Daniele De Filippis
    Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy
    PLoS ONE 6:e28159. 2011
    ..These actions lead to a reduction of intestinal damage mediated by PPARgamma receptor pathway. Our results therefore indicate that CBD indeed unravels a new therapeutic strategy to treat inflammatory bowel diseases...
  13. doi request reprint Enteroglial-derived S100B protein integrates bacteria-induced Toll-like receptor signalling in human enteric glial cells
    Fabio Turco
    Department of Clinical and Experimental Medicine, Federico II University of Naples, Naples, Italy
    Gut 63:105-15. 2014
    ..We aimed to evaluate whether: EGC participate in host-bacteria interaction; S100B and Toll-like receptor (TLR) signalling converge in a common pathway leading to nitric oxide (NO) production...
  14. doi request reprint Effects of long-term PPI treatment on producing bowel symptoms and SIBO
    Debora Compare
    Department of Clinical and Experimental Medicine, Gastroenterology Unit, University of Naples Federico II, Naples, Italy
    Eur J Clin Invest 41:380-6. 2011
    ..However, relapse of symptoms occurs in the majority of the patients who require recurrent or continuous therapy. Although PPIs are well tolerated, little information is available about gastrointestinal side effects...
  15. ncbi request reprint Gastroduodenal lesions and Helicobacter pylori infection in dyspeptic patients with and without chronic renal failure
    Gerardo Nardone
    Department of Clinical and Experimental Medicine, Gastroenterology Unit, University Federico II, Via Pansini n degree 580131 Naples, Italy
    Helicobacter 10:53-8. 2005
    ..Our secondary aim was to investigate whether uremic status may affect the diagnostic efficiency of the [13]C-urea breath test ([13]C-UBT)...
  16. doi request reprint Prevalence of irritable bowel syndrome in Italian rural and urban areas
    Paolo Usai
    Gastroenterology Unit, University of Cagliari, S S 554 Bivio per Sestu, Monserrato CA, Italy
    Eur J Intern Med 21:324-6. 2010
    ..No comparative studies are available, as yet, in Italy, concerning the prevalence of irritable bowel syndrome (IBS) in urban and rural areas. The aim is to compare the prevalence of IBS in Italian urban and rural areas...
  17. doi request reprint Correlation between oesophageal acid exposure and dyspeptic symptoms in patients with nonerosive reflux disease
    Giovanni Sarnelli
    Gastroenterology Unit, Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy
    Eur J Gastroenterol Hepatol 20:264-8. 2008
    ..Oesophageal acidification induces dyspeptic symptoms in healthy individuals. This study aimed to evaluate the correlation between oesophageal acid exposure and dyspeptic symptoms in patients with nonerosive reflux disease...
  18. doi request reprint Acetonic Extract from the Feijoa sellowiana Berg. Fruit Exerts Antioxidant Properties and Modulates Disaccharidases Activities in Human Intestinal Epithelial Cells
    Fabio Turco
    Department of Clinical and Experimental Medicine, Federico II University of Naples, Naples, Italy
    Phytother Res 30:1308-15. 2016
    ..These effects may be exploited in case of disaccharidases deficit and also as an adjuvant treatment of diseases related to oxidative stress. Copyright © 2016 John Wiley & Sons, Ltd. ..
  19. pmc Partially hydrolyzed guar gum in the treatment of irritable bowel syndrome with constipation: effects of gender, age, and body mass index
    Luigi Russo
    Department of Clinical Medicine and Surgery, Gastroenterological Unit, University Federico II, Via Sergio Pansini 5, 80131, Naples, Italy
    Saudi J Gastroenterol 21:104-10. 2015
    ..We aimed to investigate the effect of PHGG in symptom relief on constipation-predominant IBS according to gender, age, and body mass index (BMI)...
  20. doi request reprint Symptom patterns can distinguish diverticular disease from irritable bowel syndrome
    Rosario Cuomo
    Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy
    Eur J Clin Invest 43:1147-55. 2013
    ..However, comparative studies are flawed by different age at onset of symptoms. We aimed to verify whether clinical features distinguish DD from IBS...
  21. ncbi request reprint Enteric glial-derived S100B protein stimulates nitric oxide production in celiac disease
    Giuseppe Esposito
    Department of Experimental Pharmacology, University Federico II, Naples, Italy
    Gastroenterology 133:918-25. 2007
    ..In this study, we evaluated the expression of S100B and its relationship with nitric oxide production in celiac disease...
  22. doi request reprint Proton pump inhibitors prescribing following the introduction of generic drugs
    Simona Cammarota
    CIRFF Center of Pharmacoeconomics and Drug Utilization, Faculty of Pharmacy, University of Naples Federico II, Naples, Italy
    Eur J Clin Invest 42:1068-78. 2012
    ..In many countries, the introduction of generic proton pump inhibitors (PPIs) onto the pharmaceutical market increased the phenomenon of therapeutic substitution in acid-related disorders (ARDs)...
  23. ncbi request reprint Effects of carbonated water on functional dyspepsia and constipation
    Rosario Cuomo
    Epatogastroenterologia, Dipartimento di Medicina Clinica e Sperimentale, Universita degli Studi di Napoli Federico II, Via Sergio Pansini 5, 80131 Naples, Italy
    Eur J Gastroenterol Hepatol 14:991-9. 2002
    ..The effects of carbonated beverages on the gastrointestinal tract have been poorly investigated. Therefore, this study aims to assess the effect of carbonated water intake in patients with functional dyspepsia and constipation...
  24. ncbi request reprint Functional dyspepsia symptoms, gastric emptying and satiety provocative test: analysis of relationships
    R Cuomo
    Dipartimento di Medicina Clinica e Sperimentale, Universita degli Studi di Napoli Federico II, Italy
    Scand J Gastroenterol 36:1030-6. 2001
    ....
  25. ncbi request reprint Rationale and evidences for treatment of symptomatic uncomplicated diverticular disease
    Rosario Cuomo
    Gastroenterology, Department of Clinical Medicine and Surgery, School of Medicine and quot Federico II of Naples and quot, Naples, Italy
    Minerva Gastroenterol Dietol . 2016
    ..The present article aims to review the current data for medical management of SUDD...
  26. pmc Molecular Signaling and Dysfunction of the Human Reactive Enteric Glial Cell Phenotype: Implications for GI Infection, IBD, POI, Neurological, Motility, and GI Disorders
    Andrómeda Liñán-Rico
    Department of Anesthesiology, Wexner Medical Center, The Ohio State University, Columbus, Ohio Gastroenterological Unit, Department of Clinical and Experimental Medicine, Federico II University of Naples, Naples, Italy Department of Surgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio Department of Internal Medicine, Wexner Medical Center, The Ohio State University, Columbus, Ohio Center for Biostatistics, Wexner Medical Center, The Ohio State University, Columbus, Ohio Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio and Nationwide Children s Hospital, Department of Anesthesiology and Pain Medicine, Columbus, Ohio
    Inflamm Bowel Dis 22:1812-34. 2016
    ..Mechanisms underlying glial responses to inflammation in human GI tract are not understood. Our goal was to identify the "reactive human enteric glial cell (rhEGC) phenotype" induced by inflammation, and probe its functional relevance...
  27. pmc Good adherence to mediterranean diet can prevent gastrointestinal symptoms: A survey from Southern Italy
    Francesco Paolo Zito
    Francesco Paolo Zito, Barbara Polese, Letizia Vozzella, Antonietta Gala, Daniela Genovese, Viviana Verlezza, Fabiana Medugno, Martina Cargiolli, Paolo Andreozzi, Giovanni Sarnelli, Rosario Cuomo, Department of Surgery, Gastroenterology and Endocrinology, University of Naples Federico II, Naples, 80131 Campania, Italy
    World J Gastrointest Pharmacol Ther 7:564-571. 2016
    ..To evaluate how different levels of adherence to a mediterranean diet (MD) correlate with the onset of functional gastrointestinal disorders...
  28. doi request reprint Effect of gluten-free diet on preventing recurrence of gastroesophageal reflux disease-related symptoms in adult celiac patients with nonerosive reflux disease
    Paolo Usai
    Gastroenterology Unit, University of Cagliari, Monserrato, CA, Italy
    J Gastroenterol Hepatol 23:1368-72. 2008
    ..The aim of this study was to establish the recurrence of GERD-rs, in CD patients with nonerosive reflux disease (NERD)...
  29. ncbi request reprint Acid exposure and altered acid clearance in GERD patients treated for Helicobacter pylori infection
    G Sarnelli
    Department of Clinical and Experimental Medicine, Division of Hepatogastroenterology, University Federico II, Via Sergio Pansini 5, 80131 Naples, Italy
    Dig Liver Dis 35:151-6. 2003
    ..After the eradication of Helicobacter pylori, an increased incidence of gastroesophageal reflux disease and acid gastric secretion have been reported...
  30. pmc Palmitoylethanolamide Modulates Inflammation-Associated Vascular Endothelial Growth Factor (VEGF) Signaling via the Akt/mTOR Pathway in a Selective Peroxisome Proliferator-Activated Receptor Alpha (PPAR-α)-Dependent Manner
    Giovanni Sarnelli
    Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy
    PLoS ONE 11:e0156198. 2016
    ..Beyond its anti-inflammatory effect, palmitoylethanolamide (PEA) is able to reduce angiogenesis in several chronic inflammatory conditions, but no data about its anti-angiogenic activity in colitis have been produced, yet...
  31. doi request reprint Treatment of diverticular disease of the colon and prevention of acute diverticulitis: a systematic review
    Giovanni Maconi
    Gastroenterology Unit, Department of Clinical Sciences, L Sacco University Hospital, Milan, Italy
    Dis Colon Rectum 54:1326-38. 2011
    ..Diverticular disease of the colon is a common disorder, characterized by recurrent symptoms and complications such as diverticulitis, requiring hospital admissions and surgery...
  32. ncbi request reprint Effect of chronic administration of tacrolimus and cyclosporine on human gastrointestinal permeability
    Gianpaolo Parrilli
    Department of Clinical and Experimental Medicine, Division of Hepatogastroenterology, University of Naples Federico II, Naples, Italy
    Liver Transpl 9:484-8. 2003
    ..We conclude that chronic administration of FK506 or CsA induces a clinically irrelevant, selective dysfunction of monosaccharide absorption, but does not affect gastroduodenal or intestinal permeability...
  33. pmc Pseudopneumoperitoneum in chronic intestinal pseudo-obstruction: a case report
    Luigi Camera
    Department of Bio morphological and Functional Sciences, University Federico II, 80131 Naples, Italy
    World J Gastroenterol 17:2972-5. 2011
    ..The patient was submitted to pan-colonoscopy and to anorectal manometry to rule out Hirshprung's disease, and was finally discharged with a diagnosis of CIPO...
  34. doi request reprint Italian Guidelines
    Bruno Annibale
    Departments of Medical and Surgical Sciences and Traslational Medicine Internal Medicine and Medical Specialties, University Sapienza, Roma Department of Clinical Medicine and Surgery, Federico II University, Napoli, Italy
    J Clin Gastroenterol 50:S44-6. 2016
    ....
  35. pmc A patient with oeosinophilic gastroenteritis and severe malnutrition improved with home parenteral nutrition
    Lidia Santarpia
    Department of Clinical and Experimental Medicine, Federico II University Hospital, Naples, Italy
    BMJ Case Rep 2010:. 2010
    ..Here we discuss the clinical case and management of a 23-year-old man with oeosinophilic gastroenteritis since the first year of life and the decision to prescribe lifelong total parenteral nutrition...
  36. pmc Enteric Glial Cells: A New Frontier in Neurogastroenterology and Clinical Target for Inflammatory Bowel Diseases
    Fernando Ochoa-Cortes
    Department of Anesthesiology, The Ohio State University, Columbus, Ohio Department of Clinical and Experimental Medicine, Gastroenterological Unit, Federico II University of Naples, Naples, Italy and Department of Surgery, University of Bonn, Bonn, Germany
    Inflamm Bowel Dis 22:433-49. 2016
    ....
  37. ncbi request reprint Argon plasma coagulation of hemorrhagic solitary rectal ulcer syndrome
    Vincenzo Stoppino
    Gastroenterology Unit, AOU Ospedali Riuniti of Foggia, Italy
    J Clin Gastroenterol 37:392-4. 2003
    ..This experience suggests that APC may represent a therapeutic approach for bleeding SUS even if controlled studies are necessary before recommending it as acceptable treatment...
  38. doi request reprint Tissue ghrelin level and gastric emptying rate in adult patients with celiac disease
    A Rocco
    Department of Clinical and Experimental Medicine, Gastroenterology Unit, Federico II University of Naples, Naples, Italy
    Neurogastroenterol Motil 20:884-90. 2008
    ..In conclusion, tissue ghrelin level does not correlate with gastric emptying rate in adult CD patients and in controls...
  39. ncbi request reprint Role of diaphragmatic crura and lower esophageal sphincter in gastroesophageal reflux disease: manometric and pH-metric study of small hiatal hernia
    R Cuomo
    Dipartimento di Medicina Clinica e Sperimentale, Epatogastroenterologia, , Naples, Italy
    Dig Dis Sci 46:2687-94. 2001
    ..001) but not in the upright position. Hiatal hernia predisposes to GERD, but only the associated impairment of the LES and diaphragmatic crura pressures represents a condition of high risk for gastroesophageal reflux events...
  40. pmc Medical treatment of gastro-oesophageal reflux disease
    F De Giorgi
    Department of Clinical and Experimental Medicine, Division of Gastroenterology, Federico II University, Naples, Italy
    Acta Otorhinolaryngol Ital 26:276-80. 2006
    ....
  41. pmc Pathophysiology of gastro-oesophageal reflux disease
    F De Giorgi
    Department of Clinical and Experimental Medicine, Division of Gastroenterology, University Federico II, Naples, Italy
    Acta Otorhinolaryngol Ital 26:241-6. 2006
    ....
  42. ncbi request reprint A new semiquantitative method of quantifying Helicobacter pylori in antigen stools
    Enzo Ierardi
    Department of Gastroenterology, University of Foggia, Italy
    J Clin Gastroenterol 35:375-8. 2002
    ..Our data suggest that a numerical estimation of H. pylori stool antigen may be feasible. This evaluation, similarly to UBT delta, may represent a semiquantitative determination of bacterial intragastric load...
  43. ncbi request reprint Symptoms and pathophysiological correlations in patients with constipation and functional dyspepsia
    Giovanni Sarnelli
    Gastroenterologia, Dipartimento di Medicina Clinica e Sperimentale, Universita Federico II, Napoli, Italy
    Digestion 71:225-30. 2005
    ..Our aim was to study symptoms association and GI motility parameters in patients with constipation and functional dyspepsia...
  44. ncbi request reprint Symptom patterns and pathophysiological mechanisms in dyspeptic patients with and without Helicobacter pylori
    Giovanni Sarnelli
    Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, Herestraat 49, B 3000 Leuven, Belgium
    Dig Dis Sci 48:2229-36. 2003
    ..In conclusion, in patients with functional dyspepsia the presence of HP infection does not seem to affect significantly the overall prevalence of symptoms or the gastric sensory-motor functions...
  45. ncbi request reprint A hypothetical road map to reduce acid related diseases costs management
    Rosario Cuomo
    Dig Liver Dis 40:79-80. 2008
  46. ncbi request reprint Influence of motilin on gastric fundus tone and on meal-induced satiety in man: role of cholinergic pathways
    Rosario Cuomo
    Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
    Am J Gastroenterol 101:804-11. 2006
    ..It has been speculated that it is due to the contractile effect of motilin agonists on the proximal stomach, but the pathway involved and the symptomatic consequences have been incompletely elucidated...