R Tedeschi

Summary

Affiliation: Centro di Riferimento Oncologico
Country: Italy

Publications

  1. pmc Quantification of hepatitis C virus (HCV) in liver specimens and sera from patients with human immunodeficiency virus coinfection by using the Versant HCV RNA 3.0 (branched DNA-based) DNA assay
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Department, Centro di Riferimento Oncologico, IRCCS, I 33081 Aviano, Italy
    J Clin Microbiol 41:3046-50. 2003
  2. ncbi request reprint Prognostic factors in human herpesvirus 8-related lymphoproliferative disorders associated with HIV infection
    Cecilia Simonelli
    J Clin Oncol 24:209; author reply 209-10. 2006
  3. doi request reprint Assessment of immunovirological features in HIV related non-Hodgkin lymphoma patients and their impact on outcome
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Unit, Centro di Riferimento Oncologico, IRCCS, Via F Gallini 2, 33081 Aviano, Italy
    J Clin Virol 53:297-301. 2012
  4. pmc Serum antibody response to lytic and latent Epstein-Barr virus antigens in undifferentiated nasopharyngeal carcinoma patients from an area of nonendemicity
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Unit, Centro di Riferimento Oncologico, Istituto di Recovero e Cura a Carattere Scientifico, Aviano, Italy
    Clin Vaccine Immunol 14:435-41. 2007
  5. doi request reprint Human herpesvirus 8 DNA quantification in matched plasma and PBMCs samples of patients with HHV8-related lymphoproliferative diseases
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Unit, Centro di Riferimento Oncologico, IRCCS, Via F Gallini 2, 33081 Aviano, Italy
    J Clin Virol 43:255-9. 2008
  6. doi request reprint No risk of maternal EBV infection for childhood leukemia
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Unit, Centro di Riferimento Oncologico, Istituto di Ricovero e Cura a Carattere Scientifico, Aviano, 33081 Italy
    Cancer Epidemiol Biomarkers Prev 18:2790-2. 2009
  7. pmc Viral load of human herpesvirus 8 in peripheral blood of human immunodeficiency virus-infected patients with Kaposi's sarcoma
    R Tedeschi
    The Microbiology and Tumor Biology Center, Karolinska Institute, Stockholm, Sweden
    J Clin Microbiol 39:4269-73. 2001
  8. doi request reprint Plasma HHV-8 viral load in HHV-8-related lymphoproliferative disorders associated with HIV infection
    C Simonelli
    Division of Medical Oncology A, National Cancer Institute, Aviano, Italy
    J Med Virol 81:888-96. 2009
  9. ncbi request reprint Lymphocyte subsets and viral load in patients with HIV-associated non-Hodgkin's lymphoma treated with anti-CD20 monoclonal antibody and chemotherapy
    P De Paoli
    Departments of Microbiology, Immunology and Virology, Centro di Riferimento Oncologico, IRCCS, via Pedemontana, 33081 Aviano, Italy
    Cancer Immunol Immunother 50:157-62. 2001
  10. pmc A prospective seroepidemiological study of human herpesvirus-8 infection and the risk of multiple myeloma
    R Tedeschi
    Microbiology Immunology and Virology Department, Centro di Riferimento Oncologico Istituto Nazionale Tumori, Aviano, I 33081, Italy
    Br J Cancer 84:122-5. 2001

Collaborators

Detail Information

Publications31

  1. pmc Quantification of hepatitis C virus (HCV) in liver specimens and sera from patients with human immunodeficiency virus coinfection by using the Versant HCV RNA 3.0 (branched DNA-based) DNA assay
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Department, Centro di Riferimento Oncologico, IRCCS, I 33081 Aviano, Italy
    J Clin Microbiol 41:3046-50. 2003
    ..Given its positive analytical performance, the assay will be used to evaluate the HCV RNA levels in the serum and liver during follow-up of patients treated with an anti-HCV therapeutic regimen...
  2. ncbi request reprint Prognostic factors in human herpesvirus 8-related lymphoproliferative disorders associated with HIV infection
    Cecilia Simonelli
    J Clin Oncol 24:209; author reply 209-10. 2006
  3. doi request reprint Assessment of immunovirological features in HIV related non-Hodgkin lymphoma patients and their impact on outcome
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Unit, Centro di Riferimento Oncologico, IRCCS, Via F Gallini 2, 33081 Aviano, Italy
    J Clin Virol 53:297-301. 2012
    ..Despite the era of highly active antiretroviral therapy, non-Hodgkin lymphoma (NHL) remains one of the main causes of death in HIV-infected patients, with a wide variation on the outcome...
  4. pmc Serum antibody response to lytic and latent Epstein-Barr virus antigens in undifferentiated nasopharyngeal carcinoma patients from an area of nonendemicity
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Unit, Centro di Riferimento Oncologico, Istituto di Recovero e Cura a Carattere Scientifico, Aviano, Italy
    Clin Vaccine Immunol 14:435-41. 2007
    ..The analysis of serological results according to TNM classification is consistent with a progressive impairment of humoral immune response to EBV as the disease advances and may be used to improve the accuracy of diagnosis...
  5. doi request reprint Human herpesvirus 8 DNA quantification in matched plasma and PBMCs samples of patients with HHV8-related lymphoproliferative diseases
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Unit, Centro di Riferimento Oncologico, IRCCS, Via F Gallini 2, 33081 Aviano, Italy
    J Clin Virol 43:255-9. 2008
    ..The quantitative evaluation of human herpesvirus 8 (HHV8) DNA is not well described in the clinical management of HHV8-related lymphoproliferative diseases...
  6. doi request reprint No risk of maternal EBV infection for childhood leukemia
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Unit, Centro di Riferimento Oncologico, Istituto di Ricovero e Cura a Carattere Scientifico, Aviano, 33081 Italy
    Cancer Epidemiol Biomarkers Prev 18:2790-2. 2009
    ..9; 95% confidence interval, 0.5-1.8). The early antigen and ZEBRA antibodies (EBV reactivation markers) were also not associated with risk. The data argue against a role of EBV in ALL...
  7. pmc Viral load of human herpesvirus 8 in peripheral blood of human immunodeficiency virus-infected patients with Kaposi's sarcoma
    R Tedeschi
    The Microbiology and Tumor Biology Center, Karolinska Institute, Stockholm, Sweden
    J Clin Microbiol 39:4269-73. 2001
    ..HHV-8 viral load monitored by real time PCR might be useful for determination HHV-8 viral load during the follow-up of KS patients...
  8. doi request reprint Plasma HHV-8 viral load in HHV-8-related lymphoproliferative disorders associated with HIV infection
    C Simonelli
    Division of Medical Oncology A, National Cancer Institute, Aviano, Italy
    J Med Virol 81:888-96. 2009
    ..Multivariate analysis confirmed the diagnosis of lymphoma as an independent predictor of shorter survival...
  9. ncbi request reprint Lymphocyte subsets and viral load in patients with HIV-associated non-Hodgkin's lymphoma treated with anti-CD20 monoclonal antibody and chemotherapy
    P De Paoli
    Departments of Microbiology, Immunology and Virology, Centro di Riferimento Oncologico, IRCCS, via Pedemontana, 33081 Aviano, Italy
    Cancer Immunol Immunother 50:157-62. 2001
    ..These observations suggest that Rituximab plus CT accelerated the rate of CD4 depletion and of HIV replication in the peripheral blood of HIV-NHL patients and that HAART may be able to delay these effects...
  10. pmc A prospective seroepidemiological study of human herpesvirus-8 infection and the risk of multiple myeloma
    R Tedeschi
    Microbiology Immunology and Virology Department, Centro di Riferimento Oncologico Istituto Nazionale Tumori, Aviano, I 33081, Italy
    Br J Cancer 84:122-5. 2001
    ..02, CI: 0.94-4.33 and RR = 10.00, CI: 0.91-110.29, respectively). In conclusion, no statistically significant evidence for an association between HHV8 infection and the risk of future MM was found...
  11. pmc Joint Nordic prospective study on human herpesvirus 8 and multiple myeloma risk
    R Tedeschi
    Department of Microbiology Immunology and Virology, Centro di Riferimento Oncologico, Aviano, Italy
    Br J Cancer 93:834-7. 2005
    ..8, 95% CI = 0.5-1.2 and RR = 0.9, 95% CI = 0.1-4.2). In conclusion, the data indicate that HHV8 infection is not associated with MM...
  12. ncbi request reprint Human serum antibodies to a major defined epitope of human herpesvirus 8 small viral capsid antigen
    R Tedeschi
    Microbiology and Tumor Biology Center, Karolinska Institute, Stockholm, Sweden
    J Infect Dis 179:1016-20. 1999
    ..In conclusion, the defined sVCA epitope was a specific, but not very sensitive, serologic marker of active HHV-8 infection. Such infection appears to be rare among Swedish women, even with sexual risk-taking behavior...
  13. ncbi request reprint The impact of HCV co-infection on the outcome and the clinical features of HIV-related non-Hodgkin lymphoma (NHL)
    C Simonelli
    National Cancer Institute, Aviano, Italy
    J Clin Oncol 26:19504. 2008
    ..19504 Background: Epidemiological studies show an association between HCV and B NHL. Treatment and outcome of patients with NHL and HCV infection in the general population and in HIV-infected population are still debated...
  14. pmc Recent thymic emigrants in lymphoma patients with and without human immunodeficiency virus infection candidates for autologous peripheral stem cell transplantation
    C Pratesi
    Microbiology, Immunology and Virology Unit, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy
    Clin Exp Immunol 151:101-9. 2008
    ..Our results suggested that de novo T cell generation is maintained partially in pretreated recurrent lymphoma patients, candidates for ASCT, and could contribute to restore the immune function after transplantation...
  15. ncbi request reprint Laboratory diagnosis of human herpesvirus 8 infection in humans
    R Tedeschi
    Microbiology Immunology and Virology Department, Centro di Riferimento Oncologico, IRCCS, via Pedemontana Occ 12, 33081 Aviano, Italy
    Eur J Clin Microbiol Infect Dis 21:831-44. 2002
    ..The main conclusion is that more research is needed to define the most useful laboratory tests for the diagnosis of HHV-8 infection and to establish the clinical role of such tests...
  16. doi request reprint Stereotactic body radiation therapy and intensity modulated radiation therapy induce different plasmatic cytokine changes in non-small cell lung cancer patients: a pilot study
    M Trovo
    Department of Radiation Oncology, Centro di Riferimento Oncologico of Aviano, Aviano, Italy
    Clin Transl Oncol 18:1003-10. 2016
    ..To assess kinetics of plasmatic cytokines during radiation therapy (RT) for locally advanced and early-stage non-small cell lung cancer (NSCLC)...
  17. ncbi request reprint Evaluation of three molecular biology-based assays for the detection of GB virus C/hepatitis G virus in clinical specimens
    Maria Teresa Bortolin
    Microbiology Immunology and Virology Department, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy
    Intervirology 47:314-20. 2004
    ..We, therefore, investigated the virus prevalence with the method that gave us the best performances...
  18. ncbi request reprint Interferon-gamma secretion and perforin expression are impaired in CD8+ T lymphocytes from patients with undifferentiated carcinoma of nasopharyngeal type
    Stefania Zanussi
    Department of Microbiology, Immunology and Virology, Centro di Riferimento Oncologico, IRCCS, Via Pedemontana 12, 33081 Aviano, Italy
    Cancer Immunol Immunother 52:28-32. 2003
    ..In UCNT patients, the blockade of the perforin pathway and of IFN-gamma production may constitute important mechanisms for immune escape by the tumor and for impaired control of EBV replication...
  19. ncbi request reprint Quantitative plasma/serum EBV DNA load by LMP2A determination in an Italian cohort of NPC patients
    Chiara Pratesi
    Microbiology Unit, Centro di Riferiferimento Oncologico, Via Pedemontana Occidentale, 12, 33081, Aviano, PN, Italy
    J Clin Virol 28:155-64. 2003
    ..Nasopharyngeal carcinoma (NPC) is frequently associated with Epstein-Barr virus (EBV), but little is known about the EBV DNA prevalence on peripheral blood in Western Countries, where the tumour is not endemic and its incidence is low...
  20. ncbi request reprint Antibodies against Kaposi sarcoma-associated herpes virus (KSHV) complement control protein (KCP) in infected individuals
    Marcin Okroj
    Department of Laboratory Medicine, Lund University, University Hospital Malmo, S 205 02 Malmo, Sweden
    Vaccine 25:8102-9. 2007
    ..Furthermore, pre-incubation of KCP-expressing CHO cells with patient sera containing anti-KCP antibodies resulted in an increased complement deposition when incubated with human serum...
  21. ncbi request reprint Clinical features and outcome of primary effusion lymphoma in HIV-infected patients: a single-institution study
    Cecelia Simonelli
    Division of Medical Oncology A, National Cancer Institute, Aviano, Italy
    J Clin Oncol 21:3948-54. 2003
    ..To describe the clinical features and outcome of HIV-associated primary effusion lymphoma (PEL) and to compare them with those of the other HIV-associated non-Hodgkin's lymphomas (NHLs)...
  22. ncbi request reprint Activation of maternal Epstein-Barr virus infection and risk of acute leukemia in the offspring
    Rosamaria Tedeschi
    Department of Microbiology, Oncological Center, Aviano, Italy
    Am J Epidemiol 165:134-7. 2007
    ..3, 16; odds ratio = 5.6, 95% confidence interval: 1.1, 29, respectively), suggesting EBV reactivation in the mothers of non-ALL cases. EBV reactivation may be associated with a proportion of childhood leukemia...
  23. ncbi request reprint Clinical value of Epstein-Barr virus DNA levels in peripheral blood samples of Italian patients with undifferentiated carcinoma of nasopharyngeal type
    Maria Teresa Bortolin
    Microbiology, Immunology and Virology Unit, Centro di Riferimento Oncologico, IRCCS, Via Pedemontana Occidentale, 12, Aviano PN 33081, Italy
    Cancer Lett 233:247-54. 2006
    ..008). We concluded that serum EBV DNA reflects the biological activity of the UCNT and may be a prognostic factor also in a low-incidence region...
  24. ncbi request reprint Epidemiology of Kaposi's Sarcoma herpesvirus (HHV8) in Västerbotten County, Sweden
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Department, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy
    J Med Virol 78:372-8. 2006
    ..25-0.77 and OR: 0.50, 95% CI: 0.26-0.95, respectively). In summary, HHV8 has an intermediate high and stable seroprevalence rate in Northern Sweden, but environmental determinants that can explain the viral distribution were not found...
  25. ncbi request reprint Characterization of immunologic and virological parameters in HIV-infected patients with primary effusion lymphoma during antiblastic therapy and highly active antiretroviral therapy
    Cecilia Simonelli
    Division of Medical Oncology A, National Cancer Institute, Aviano, Italy
    Clin Infect Dis 40:1022-7. 2005
    ..The aim of the present study was to evaluate the immunologic and virological parameters, including HHV-8 viremia, of 5 HIV-infected patients with PEL whose disease was diagnosed and treated at our institute...
  26. ncbi request reprint Interleukin-10 and interleukin-18 promoter polymorphisms in an Italian cohort of patients with undifferentiated carcinoma of nasopharyngeal type
    Chiara Pratesi
    Microbiology, Immunology and Virology Unit, Centro di Riferimento Oncologico, 33081, Aviano, Italy
    Cancer Immunol Immunother 55:23-30. 2006
    ....
  27. ncbi request reprint No serological evidence of association between prostate cancer and infection with herpes simplex virus type 2 or human herpesvirus type 8: a nested case-control study
    Zoltan Korodi
    Department of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Infect Dis 191:2008-11. 2005
    ..Neither HSV-2 infection (odds ratio [OR], 0.93 [95% confidence interval {CI}, 0.44-1.96]) nor HHV-8 infection (OR, 0.74 [95% CI, 0.19-2.88]) was associated with prostate cancer...
  28. ncbi request reprint Hepatitis C virus infection does not prevent autologous bone marrow transplantation in HIV-related non-Hodgkin's lymphoma
    Cecilia Simonelli
    AIDS 18:1859-61. 2004
  29. pmc Heterogeneity of cag genotypes in Helicobacter pylori isolates from human biopsy specimens
    Maria Luisa Tomasini
    Microbiology, Immunology, and Virology Gastroenterology Units, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy
    J Clin Microbiol 41:976-80. 2003
    ..The extension of our analysis to patients with well-characterized gastric diseases may provide significant information on the relationship between cag genotypes and clinical outcomes of H. pylori infections...
  30. ncbi request reprint Efficacy and safety of combined treatment with pegylated-IFN-alpha 2b plus ribavirin in HIV-hepatitis C virus-co-infected patients
    Roberta Cinelli
    AIDS 18:1079-80. 2004
  31. ncbi request reprint Effects on virological and immunological parameters during CD34 mobilization in HIV patients with lymphoma
    Maria Teresa Bortolin
    Microbiology, Immunology and Virology Unit, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy
    Am J Hematol 81:800-2. 2006
    ..After mobilization, CD4+ cells increased significantly while HIV-RNA and integrated HIV-DNA showed no increases. G-CSF led to an increase of CD4+ cells with limited effects on HIV replication...