Alfonso Fasano

Summary

Affiliation: Catholic University
Country: Italy

Publications

  1. ncbi Dystonia gravidarum: a new case with a long follow-up
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Mov Disord 22:564-6. 2007
  2. doi Cocaine addiction: from habits to stereotypical-repetitive behaviors and punding
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Largo Agostino Gemelli, 8 00168 Roma, Italy
    Drug Alcohol Depend 96:178-82. 2008
  3. doi Tetrabenazine
    Alfonso Fasano
    Universita Cattolica del Sacro Cuore, Istituto di Neurologia, Largo Agostino Gemelli, 8 00168 Roma, Italy
    Expert Opin Pharmacother 10:2883-96. 2009
  4. doi The neurobiology of falls
    Alfonso Fasano
    Department of Neurology, Catholic University, Rome, Italy
    Neurol Sci 33:1215-23. 2012
  5. doi Status dystonicus: predictors of outcome and progression patterns of underlying disease
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Mov Disord 27:783-8. 2012
  6. ncbi Intrajejunal levodopa infusion in advanced Parkinson's disease: long-term effects on motor and non-motor symptoms and impact on patient's and caregiver's quality of life
    A Fasano
    Department of Neurology, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Eur Rev Med Pharmacol Sci 16:79-89. 2012
  7. doi Aceruloplasminemia: a novel mutation in a family with marked phenotypic variability
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italy
    Mov Disord 23:751-5. 2008
  8. doi Insights into pathophysiology of punding reveal possible treatment strategies
    A Fasano
    Department of Neuroscience, Catholic University of Sacred Heart, Rome, Italy
    Mol Psychiatry 15:560-73. 2010
  9. doi GPi-DBS in Huntington's disease: results on motor function and cognition in a 72-year-old case
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italia
    Mov Disord 23:1289-92. 2008
  10. doi The long-term effect of tetrabenazine in the management of Huntington disease
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italy
    Clin Neuropharmacol 31:313-8. 2008

Detail Information

Publications51

  1. ncbi Dystonia gravidarum: a new case with a long follow-up
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Mov Disord 22:564-6. 2007
    ....
  2. doi Cocaine addiction: from habits to stereotypical-repetitive behaviors and punding
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Largo Agostino Gemelli, 8 00168 Roma, Italy
    Drug Alcohol Depend 96:178-82. 2008
    ..In conclusion, RRSB and punding is much more common than has been described previously and the resultant social disability is often overlooked...
  3. doi Tetrabenazine
    Alfonso Fasano
    Universita Cattolica del Sacro Cuore, Istituto di Neurologia, Largo Agostino Gemelli, 8 00168 Roma, Italy
    Expert Opin Pharmacother 10:2883-96. 2009
    ..Tetrabenazine (TBZ) depletes presynaptic dopamine in the CNS. It has been found to be beneficial in hyperkinetic movement disorders without carrying the extrapyramidal side effects that are characteristic of neuroleptics...
  4. doi The neurobiology of falls
    Alfonso Fasano
    Department of Neurology, Catholic University, Rome, Italy
    Neurol Sci 33:1215-23. 2012
    ..This translational approach will lead to the development of specific therapeutic interventions...
  5. doi Status dystonicus: predictors of outcome and progression patterns of underlying disease
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Mov Disord 27:783-8. 2012
    ..Status dystonicus (SD) is a rare, life-threatening disorder characterized by acute worsening of generalized dystonia...
  6. ncbi Intrajejunal levodopa infusion in advanced Parkinson's disease: long-term effects on motor and non-motor symptoms and impact on patient's and caregiver's quality of life
    A Fasano
    Department of Neurology, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Eur Rev Med Pharmacol Sci 16:79-89. 2012
    ..Aim of this two-center, retrospective, open-label study was to evaluate the long-term effect of CIILG on patients' condition and caregivers' quality of life...
  7. doi Aceruloplasminemia: a novel mutation in a family with marked phenotypic variability
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italy
    Mov Disord 23:751-5. 2008
    ..Possible physiopathological bases of these intrafamilial phenotypic variations are discussed...
  8. doi Insights into pathophysiology of punding reveal possible treatment strategies
    A Fasano
    Department of Neuroscience, Catholic University of Sacred Heart, Rome, Italy
    Mol Psychiatry 15:560-73. 2010
    ..Punding may be related to plastic changes in the ventral and dorsal striatal structures, including the nucleus accumbens, and linked to psychomotor stimulation and reward mechanisms. Possible management guidelines are proposed...
  9. doi GPi-DBS in Huntington's disease: results on motor function and cognition in a 72-year-old case
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italia
    Mov Disord 23:1289-92. 2008
    ..The cognitive profile showed a progressive deterioration, with an extension of deficit from the mainly dysexecutive alterations at baseline to a more diffused cognitive deterioration...
  10. doi The long-term effect of tetrabenazine in the management of Huntington disease
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italy
    Clin Neuropharmacol 31:313-8. 2008
    ..To enhance the knowledge on the long-term efficacy and safety of tetrabenazine (TBZ) in managing chorea...
  11. doi High frequency extradural motor cortex stimulation transiently improves axial symptoms in a patient with Parkinson's disease
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italia
    Mov Disord 23:1916-9. 2008
    ..After five months, the benefit of EMCS gradually disappeared...
  12. ncbi Myasthenia gravis: an unrecognized cause of head drop in Parkinson's disease
    A Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italia
    Parkinsonism Relat Disord 14:164-5. 2008
    ..Clinical, radiological, and neurophysiological features together with responsiveness to anticholinesterases and plasma exchanges indicated the possibility of a concomitant myasthenia gravis...
  13. doi Management of punding in Parkinson's disease: an open-label prospective study
    A Fasano
    Istituto di Neurologia, Università Cattolica del Sacro Cuore Largo Agostino Gemelli, 8, 00168 Rome, Italy
    J Neurol 258:656-60. 2011
    ..In two cases, reduction of levodopa therapy was efficacious; amantadine was effective in controlling punding in four cases; in the remaining cases, quetiapine was employed, with mild efficacy in two cases...
  14. ncbi Unilateral extradural motor cortex stimulation is safe and improves Parkinson disease at 1 year
    Anna Rita Bentivoglio
    Neurology, Catholic University, and Department of Neuroscience, AFaR Fatebenefratelli Hospital, Rome, Italy
    Neurosurgery 71:815-25. 2012
    ..The primary motor cortex, which is part of the corticobasal ganglia loops, may be an alternative option for the surgical treatment of Parkinson disease...
  15. doi Motor and cognitive outcome in patients with Parkinson's disease 8 years after subthalamic implants
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Brain 133:2664-76. 2010
    ..However, the global benefit partly decreases later in the course of the disease, due to progression of Parkinson's disease and the appearance of medication- and stimulation-resistant symptoms...
  16. doi Treatment of motor and non-motor features of Parkinson's disease with deep brain stimulation
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Lancet Neurol 11:429-42. 2012
    ..More evidence on the effects of DBS on non-motor symptoms is needed and specifically designed studies are warranted...
  17. ncbi Non-DYT1 early-onset primary torsion dystonia: comparison with DYT1 phenotype and review of the literature
    Alfonso Fasano
    Universita Cattolica del Sacro Cuore, Roma, Italy
    Mov Disord 21:1411-8. 2006
    ..Cranial involvement before 21 years of age is the strongest predictor of non-DYT1 status. Positive family history and cervical involvement are associated with less severe progression in non-DYT1 forms...
  18. doi Dopaminergic dysfunction and psychiatric symptoms in movement disorders: a 123I-FP-CIT SPECT study
    Daniela Di Giuda
    Istituto di Medicina Nucleare, Universita Cattolica del Sacro Cuore, Rome, Italy
    Eur J Nucl Med Mol Imaging 39:1937-48. 2012
    ....
  19. doi Chronic motor cortex stimulation in patients with advanced Parkinson's disease and effects on striatal dopaminergic transmission as assessed by 123I-FP-CIT SPECT: a preliminary report
    Daniela Di Giuda
    aDepartment of Bioimages and Radiological Sciences, Institute of Nuclear Medicine, Catholic University of Sacred Heart, Largo A Gemelli, 8 00168 Rome, Italy
    Nucl Med Commun 33:933-40. 2012
    ....
  20. doi Punding in non-demented Parkinson's disease patients: Relationship with psychiatric and addiction spectrum comorbidity
    Mauro Pettorruso
    Institute of Psychiatry and Psychology, Department of Neuroscience, Catholic University of the Sacred Heart, Rome, Italy Electronic address
    J Neurol Sci 362:344-7. 2016
    ..Punding shares similarities with addictive behaviors and is associated to other psychiatric symptoms involving dopamine system alterations...
  21. doi Liquid melevodopa versus standard levodopa in patients with Parkinson disease and small intestinal bacterial overgrowth
    Alfonso Fasano
    Movement Disorders Center, TWH, UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada Departments of Neurology, and Internal Medicine, Catholic University of Sacred Heart, Gemelli University Hospital, Rome, Italy Department of Pharmacology, Catholic University of Sacred Heart, Rome, Italy and Medical Direction, Chiesi Farmaceutici, Parma, Italy
    Clin Neuropharmacol 37:91-5. 2014
    ..Aim of this study was to test the efficacy of liquid levodopa with higher bioavailability in patients with SIBO...
  22. doi Rivastigmine as alternative treatment for refractory REM behavior disorder in Parkinson's disease
    Raffaella Di Giacopo
    Movement Disorders Research Center, Department of Neuroscience, Catholic University, Rome, Italy
    Mov Disord 27:559-61. 2012
    ..We report on a double-blind, crossover pilot trial for the treatment of rapid eye movement behavior disorder (RBD) in 12 patients with Parkinson's disease in whom conventional therapy failed...
  23. doi Selective impairment of action-verb naming and comprehension in progressive supranuclear palsy
    Antonio Daniele
    Institute of Neurology, Catholic University, Rome, Italy
    Cortex 49:948-60. 2013
    ....
  24. doi Nigro-striatal involvement in primary progressive freezing gait: insights into a heterogeneous pathogenesis
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italy
    Parkinsonism Relat Disord 18:578-84. 2012
    ..Dopamine transporter imaging can capture the clinical heterogeneity of PPFG and might have a value to predict possible disease progression...
  25. ncbi Punding and computer addiction in Parkinson's disease
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Mov Disord 21:1217-8. 2006
    ..The patient had the feeling he was forced into a disruptive and unproductive behavior, and he made several attempts to quit without succeeding...
  26. pmc Psychogenic facial movement disorders: clinical features and associated conditions
    Alfonso Fasano
    Dipartimento di Neuroscience, Universita Cattolica del Sacro Cuore, Rome, Italy
    Mov Disord 27:1544-51. 2012
    ..4%). Fixed jaw and/or lip deviation is a characteristic pattern of psychogenic facial movement disorders, occurring in isolation or in combination with other psychogenic movement disorders or other psychogenic features...
  27. doi The role of small intestinal bacterial overgrowth in Parkinson's disease
    Alfonso Fasano
    Department of Neurology, Catholic University of Sacred Heart, Gemelli University Hospital, Rome, Italy
    Mov Disord 28:1241-9. 2013
    ..The relapse rate of small intestinal bacterial overgrowth at 6 months was 43%. © 2013 Movement Disorder Society. ..
  28. doi Neuropsychology, neuroimaging or motor phenotype in diagnosis of Parkinson's disease-dementia: which matters most?
    Francesca Di Biasio
    Sapienza, University of Rome, Rome, Italy
    J Neural Transm (Vienna) 119:597-604. 2012
    ..In conclusion, the use of an extensive neuropsychological battery is still recommended in the diagnosis of dementia in PD...
  29. doi Retrospective evaluation of the dose equivalence of Botox(®) and Dysport (®) in the management of blepharospasm and hemifacial spasm: a novel paradigm for a never ending story
    Anna Rita Bentivoglio
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Largo Agostino Gemelli, 8, 00168 Rome, Italy
    Neurol Sci 33:261-7. 2012
    ..In conclusion, even if the 1:4 ratio might be reliable for clinical purpose, a true bioequivalence between Dysport(®) and Botox(®) might not exist due to the intrinsic difference in their pharmacokinetic properties...
  30. doi Botulinum toxin A versus B in sialorrhea: a prospective, randomized, double-blind, crossover pilot study in patients with amyotrophic lateral sclerosis or Parkinson's disease
    Arianna Guidubaldi
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italia
    Mov Disord 26:313-9. 2011
    ..Either botulinum toxins (BoNTs) A and B have been used for improving drooling in different neurological conditions...
  31. ncbi Analysis of blink rate in patients with blepharospasm
    Anna Rita Bentivoglio
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italy
    Mov Disord 21:1225-9. 2006
    ..These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages...
  32. ncbi Homotoxicological remedies versus desmopressin versus placebo in the treatment of enuresis: a randomised, double-blind, controlled trial
    Pietro Ferrara
    Department of Paediatric Sciences, Universita Cattolica S Cuore, A Gemelli Hospital, Largo A Gemelli, 8, 00168, Rome, Italy
    Pediatr Nephrol 23:269-74. 2008
    ..Our study demonstrates that homotoxicology is safe and effective when compared with placebo, even if it is significantly less effective than dDAVP in this clinical condition...
  33. ncbi Increased excretion of glycosaminoglycans in children with urinary incontinence compared to those with monosymptomatic nocturnal enuresis
    Pietro Ferrara
    Department of Pediatrics, Universita Cattolica S Cuore, A Gemelli Hospital, Rome, Italy
    Scand J Urol Nephrol 41:218-22. 2007
    ..To analyse the urinary excretion of glycosaminoglycans (GAGs) in patients with either urinary incontinence or nocturnal enuresis...
  34. doi Outcome predictors, efficacy and safety of Botox and Dysport in the long-term treatment of hemifacial spasm
    A R Bentivoglio
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italia
    Eur J Neurol 16:392-8. 2009
    ..To review the clinical characteristics and the long-term outcome of patients with hemifacial spasm (HFS) who received botulinum neurotoxin (BoNT) over the past 10 years...
  35. doi Fifteen-year experience in treating blepharospasm with Botox or Dysport: same toxin, two drugs
    A R Bentivoglio
    Istituto di Neurologia Università Cattolica del Sacro Cuore Largo Agostino Gemelli, 8 00168 Rome, Italy
    Neurotox Res 15:224-31. 2009
    ..To compare the clinical characteristics and the long-term outcome of a large series of patients with blepharospasm (BS) treated with the two most used brands of BoNT-A over the last 15 years...
  36. pmc Impulsive-compulsive behaviors in parkin-associated Parkinson disease
    Francesca Morgante
    From the Department of Clinical and Experimental Medicine F M, C S, University of Messina, Italy Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J Safra Program in Parkinson s Disease A F, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Canada Department of Neurology and Psychiatry S P, Sapienza University of Rome, Italy Sobell Department of Motor Neuroscience and Movement Disorders L R, Institute of Neurology, University College London, UK Department of Geriatrics, Neuroscience and Orthopedics F B, A R B, Universita Cattolica del Sacro Cuore, Rome Department of Neurosciences, Reproductive and Odontostomatological Sciences C C, M M, A D R, G D M, Federico II University, Naples Department of Medicine and Surgery M G, M M, P B, M T P, E M V, Neuroscience Section, University of Salerno, and Neurogenetics Unit E M V, IRCCS Santa Lucia Foundation, Rome, Italy
    Neurology 87:1436-1441. 2016
    ....
  37. doi Anhedonia in Parkinson's disease patients with and without pathological gambling: a case-control study
    Mauro Pettorruso
    Department of Psychiatry, Drug Addiction Unit, Catholic University of the Sacred Heart, Rome, Italy Electronic address
    Psychiatry Res 215:448-52. 2014
    ....
  38. doi Finding gaps and building bridges in movement disorders
    Alfonso Fasano
    Department of Neuroscience, Catholic University, Rome, Italy
    Expert Rev Neurother 12:781-4. 2012
    ..This meeting report summarizes the topics that gathered the most attention from the speakers and the audience...
  39. ncbi Clinical presentation and progression of sporadic and familial primary torsion dystonia in Italy
    Anna Rita Bentivoglio
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Adv Neurol 94:171-8. 2004
  40. ncbi Treatment with botulinum toxin in a patient with myasthenia gravis and cervical dystonia
    A Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Neurology 64:2155-6. 2005
  41. doi New olfactometric findings in Parkinson's Disease
    Giulio Cesare Passali
    Institute of Otorhinolaryngology, Head and Neck Surgery, Catholic University of Sacred Heart, Rome, Italy
    Clin Otolaryngol . 2016
    ..to investigate in Parkinson's Disease affected patients a correlation between hyposmia and gastrointestinal dysfunction and their possible identical etiopathogenesis...
  42. doi Somatosensory temporal discrimination in essential tremor and isolated head and voice tremors
    Antonella Conte
    Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy
    Mov Disord 30:822-7. 2015
    ..This study with somatosensory temporal discrimination suggests that isolated head and voice tremors might possibly be considered as separate clinical entities from essential tremor...
  43. doi Reliability of clinical diagnosis of dystonia
    Ettore Beghi
    Department of Neuroscience, IRCCS Institute for Pharmacological Research Mario Negri, Milan, Italy
    Neuroepidemiology 43:213-9. 2014
    ..The aim of this study was to assess the inter-rater reliability of dystonia diagnosis among neurologists with different professional experience...
  44. doi Lower limb joints kinematics in essential tremor and the effect of thalamic stimulation
    Alfonso Fasano
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Roma, Italy
    Gait Posture 36:187-93. 2012
    ..Moreover, these results suggest that the beneficial effect of thalamic DBS on ataxic symptoms is limited to a narrow therapeutic window...
  45. doi Health care of children living with their mother in prison compared with the general population
    Pietro Ferrara
    Department of Pediatrics, Catholic University, A Gemelli Hospital, Rome
    Scand J Public Health 37:265-72. 2009
    ..We describe health care of children living in the nest areas and we compare this condition with the general population...
  46. pmc Neurologic aspects and falls
    Alfonso Fasano
    Department of Neurology, Catholic University, Rome, Italy
    Clin Cases Miner Bone Metab 9:17-20. 2012
    ....
  47. ncbi Management of status dystonicus: our experience and review of the literature
    Paolo Mariotti
    Istituto di Neuropsichiatria Infantile, Universita Cattolica del Sacro Cuore, Roma, Italia
    Mov Disord 22:963-8. 2007
    ..Our experience, combined with the data available in the literature, might permit to establish the best strategies in managing this rare and severe condition...
  48. doi Prevalence of small intestinal bacterial overgrowth in Parkinson's disease
    Maurizio Gabrielli
    Internal Medicine Department, Catholic University of Sacred Heart, Rome, Italy
    Mov Disord 26:889-92. 2011
    ..The aim of the study was to assess the prevalence of small intestinal bacterial overgrowth in PD patients...
  49. doi PINK1 heterozygous rare variants: prevalence, significance and phenotypic spectrum
    Roberta Marongiu
    IRCCS CSS Mendel Institute, Rome, Italy
    Hum Mutat 29:565. 2008
    ..Hence, their significance should be kept distinct from that of homozygous/compound heterozygous mutations, that cause parkinsonism inherited in a mendelian fashion...
  50. doi Movement disorders in multiple sclerosis: Causal or coincidental association?
    V Nociti
    Department of Neuroscience, Institute of Neurology, Catholic University, Rome, Italy
    Mult Scler 14:1284-7. 2008
    ..MD in patients with MS are often secondary to demyelinating disease. Also in cases without response to steroid treatment and demyelinating lesions in critical regions, it is not possible to exclude that MD and MS are causally related...
  51. ncbi Movement disorder due to aceruloplasminemia and incorrect diagnosis of hereditary hemochromatosis
    Alfonso Fasano
    J Neurol 254:113-4. 2007