Yehuda Ginosar

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. ncbi request reprint The site of action of epidural fentanyl in humans: the difference between infusion and bolus administration
    Yehuda Ginosar
    Department of Anesthesia, Stanford University, Stanford, California, USA
    Anesth Analg 97:1428-38. 2003
  2. ncbi request reprint The site of action of epidural fentanyl infusions in the presence of local anesthetics: a minimum local analgesic concentration infusion study in nulliparous labor
    Yehuda Ginosar
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University School of Medicine, Jerusalem, Israel
    Anesth Analg 97:1439-45. 2003
  3. ncbi request reprint ED50 and ED95 of intrathecal hyperbaric bupivacaine coadministered with opioids for cesarean delivery
    Yehuda Ginosar
    Department of Anesthesia, Stanford University, California, USA
    Anesthesiology 100:676-82. 2004
  4. ncbi request reprint The ED50 and ED95 of intrathecal isobaric bupivacaine with opioids for cesarean delivery
    Brendan Carvalho
    Department of Anesthesia, Stanford University School of Medicine, California 94305, USA
    Anesthesiology 103:606-12. 2005
  5. doi request reprint Sympathectomy-mediated vasodilatation: a randomized concentration ranging study of epidural bupivacaine
    Yehuda Ginosar
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel
    Can J Anaesth 56:213-21. 2009
  6. doi request reprint Proliposomal Ropivacaine Oil: Pharmacokinetic and Pharmacodynamic Data After Subcutaneous Administration in Volunteers
    Yehuda Ginosar
    From the Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, New Jersey Painreform Ltd, Israel and R and D Integrative Solutions, Israel
    Anesth Analg 122:1673-80. 2016
  7. doi request reprint High-dose bupivacaine remotely loaded into multivesicular liposomes demonstrates slow drug release without systemic toxic plasma concentrations after subcutaneous administration in humans
    Elyad M Davidson
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel
    Anesth Analg 110:1018-23. 2010
  8. doi request reprint Emergency Cesarean delivery for umbilical cord prolapse: the head-down, knee-chest prone position for spinal anesthesia
    Yehuda Ginosar
    Mother and Child Anesthesia Center, Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem, Israel 91120
    Can J Anaesth 55:612-5. 2008
  9. ncbi request reprint External cephalic version for breech presentation with or without spinal analgesia in nulliparous women at term: a randomized controlled trial
    Carolyn F Weiniger
    Department of Anesthesiology, Hadassah Hebrew University Medical Center, Ein Kerem, Jerusalem, Israel
    Obstet Gynecol 110:1343-50. 2007
  10. doi request reprint A Novel Proliposomal Ropivacaine Oil: Pharmacokinetic-Pharmacodynamic Studies After Subcutaneous Administration in Pigs
    Elyad M Davidson
    From the Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, New Jersey Painreform Ltd, Israel and R and D Integrative Solutions, Israel
    Anesth Analg 122:1663-72. 2016

Detail Information

Publications21

  1. ncbi request reprint The site of action of epidural fentanyl in humans: the difference between infusion and bolus administration
    Yehuda Ginosar
    Department of Anesthesia, Stanford University, Stanford, California, USA
    Anesth Analg 97:1428-38. 2003
    ..These findings support our hypothesis and might explain the apparent conflict in the literature regarding the site of action of epidural fentanyl...
  2. ncbi request reprint The site of action of epidural fentanyl infusions in the presence of local anesthetics: a minimum local analgesic concentration infusion study in nulliparous labor
    Yehuda Ginosar
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University School of Medicine, Jerusalem, Israel
    Anesth Analg 97:1439-45. 2003
    ..This marked increase in potency for the epidural route is highly suggestive for a predominantly spinal mechanism of action for infused epidural fentanyl under the conditions of this study...
  3. ncbi request reprint ED50 and ED95 of intrathecal hyperbaric bupivacaine coadministered with opioids for cesarean delivery
    Yehuda Ginosar
    Department of Anesthesia, Stanford University, California, USA
    Anesthesiology 100:676-82. 2004
    ..This double-blind, randomized, dose-ranging study determined the ED50 and ED95 of intrathecal bupivacaine (with adjuvant opioids) for cesarean delivery anesthesia...
  4. ncbi request reprint The ED50 and ED95 of intrathecal isobaric bupivacaine with opioids for cesarean delivery
    Brendan Carvalho
    Department of Anesthesia, Stanford University School of Medicine, California 94305, USA
    Anesthesiology 103:606-12. 2005
    ..This study determined the ED50 and ED95 of intrathecal isobaric bupivacaine (with adjuvant opioids) for cesarean delivery...
  5. doi request reprint Sympathectomy-mediated vasodilatation: a randomized concentration ranging study of epidural bupivacaine
    Yehuda Ginosar
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel
    Can J Anaesth 56:213-21. 2009
    ..We tested the hypothesis that the development of sympathectomy-mediated vasodilatation is dependent on the concentration rather than the dose of epidural local anesthetic administered...
  6. doi request reprint Proliposomal Ropivacaine Oil: Pharmacokinetic and Pharmacodynamic Data After Subcutaneous Administration in Volunteers
    Yehuda Ginosar
    From the Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, New Jersey Painreform Ltd, Israel and R and D Integrative Solutions, Israel
    Anesth Analg 122:1673-80. 2016
    ..In this study, we present both pharmacodynamic and pharmacokinetic data in healthy volunteers after subcutaneous injection of this novel proliposomal preparation of ropivacaine...
  7. doi request reprint High-dose bupivacaine remotely loaded into multivesicular liposomes demonstrates slow drug release without systemic toxic plasma concentrations after subcutaneous administration in humans
    Elyad M Davidson
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel
    Anesth Analg 110:1018-23. 2010
    ..In this study, we present pharmacokinetic data of LMVV liposomal bupivacaine in humans...
  8. doi request reprint Emergency Cesarean delivery for umbilical cord prolapse: the head-down, knee-chest prone position for spinal anesthesia
    Yehuda Ginosar
    Mother and Child Anesthesia Center, Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem, Israel 91120
    Can J Anaesth 55:612-5. 2008
    ..We describe the anesthetic management of a parturient who was rushed to the operating room, in the knee-chest prone position, because of cord prolapse with variable decelerations of fetal heart rate...
  9. ncbi request reprint External cephalic version for breech presentation with or without spinal analgesia in nulliparous women at term: a randomized controlled trial
    Carolyn F Weiniger
    Department of Anesthesiology, Hadassah Hebrew University Medical Center, Ein Kerem, Jerusalem, Israel
    Obstet Gynecol 110:1343-50. 2007
    ..To compare the success of external cephalic version using spinal analgesia with no analgesia among nulliparas...
  10. doi request reprint A Novel Proliposomal Ropivacaine Oil: Pharmacokinetic-Pharmacodynamic Studies After Subcutaneous Administration in Pigs
    Elyad M Davidson
    From the Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, New Jersey Painreform Ltd, Israel and R and D Integrative Solutions, Israel
    Anesth Analg 122:1663-72. 2016
    ..Liposomal local anesthetics are limited by a short liposomal shelf-life, even when under refrigeration. We describe a novel proliposomal ropivacaine that produces liposomes in situ, only after exposure to aqueous media...
  11. ncbi request reprint Pain management and regional anaesthesia in the trauma patient
    Elyad M Davidson
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Ein Karem, Jerusalem, Israel
    Curr Opin Anaesthesiol 18:169-74. 2005
    ..Nevertheless, the treatment of pain as part of overall trauma management has been relatively neglected. This update reviews recent publications related to pain relief in the trauma patient...
  12. pmc Performance of aseptic technique during neuraxial analgesia for labor before and after the publication of international guidelines on aseptic technique
    Alex Ioscovich
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel
    Isr J Health Policy Res 3:9. 2014
    ....
  13. doi request reprint Suspected placenta accreta and cesarean hysterectomy: observational cohort utilizing an intraoperative decision strategy
    Carolyn F Weiniger
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA, USA Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel Electronic address
    Eur J Obstet Gynecol Reprod Biol 198:56-61. 2016
    ..We examined CH frequency and post-operative morbidities for suspected PA cases when an intra-operative decision strategy to perform CH was used...
  14. ncbi request reprint Peripheral nerve block for ambulatory surgery and postoperative analgesia
    Alexander Avidan
    Department of Anesthesiology and Critical Care Medicine, Hebrew University Hadassah Medical School, Hadassah University Hospital, Jerusalem, Israel
    Curr Opin Anaesthesiol 16:567-73. 2003
    ..With this article we intend to increase the awareness of the efficiency and efficacy of peripheral nerve block as a treatment option for outpatient surgical anesthesia and postoperative home-based analgesia...
  15. doi request reprint Inhaled carbon dioxide causes dose-dependent paradoxical bradypnea in animals anesthetized with pentobarbital, but not with isoflurane or ketamine
    Yehuda Ginosar
    Department of Anesthesiology and Critical Care Medicine, Jerusalem, Israel Electronic address
    Respir Physiol Neurobiol 217:1-7. 2015
    ..In spontaneously breathing mice anesthetized with pentobarbital, we observed unexpected paradoxical bradypnea following 5% inhaled CO2...
  16. doi request reprint A randomized controlled trial of the efficacy and respiratory effects of patient-controlled intravenous remifentanil analgesia and patient-controlled epidural analgesia in laboring women
    Daniel Stocki
    From the Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem Department of Anesthesiology and Intensive Care, Tel Aviv Medical Center, Tel Aviv Intensive Care Unit, Shaare Zedek Medical Center Department of Neonatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel and Department of Anesthesia, Stanford School of Medicine, Stanford, California
    Anesth Analg 118:589-97. 2014
    ..Safe and effective alternatives are required in labor when epidural analgesia is not appropriate. We hypothesized that patient-controlled IV remifentanil labor analgesia would not be inferior to patient-controlled epidural labor analgesia...
  17. pmc Comparison of the obstetric anesthesia activity index with total delivery numbers as a single denominator of workload demand in Israeli maternity units
    Yehuda Ginosar
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Isr J Health Policy Res 1:48. 2012
    ....
  18. ncbi request reprint Perioperative management of chronic pain patients with opioid dependency
    Silviu Brill
    Sheba Medical Center, Department of Anesthesia and Intensive Care, Tel Hashomer, and Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Curr Opin Anaesthesiol 19:325-31. 2006
    ....
  19. ncbi request reprint Initial trauma management in advanced pregnancy
    Yuval Meroz
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, POB 12000, Ein Karem, Jerusalem 91120, Israel
    Anesthesiol Clin 25:117-29, x. 2007
    ..Fetal monitoring is important to assess both fetal and maternal welfare. Imaging examinations, where indicated, should not be delayed. Even minor maternal trauma, especially if caused by interpersonal violence, might cause fetal loss...
  20. doi request reprint Pregnancy in Marfan syndrome after aortic root replacement: a case report and review of the literature
    Vania Volach
    Obstetrics and Gynecology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Congenit Heart Dis 1:184-8. 2006
    ..Although acute aortic dissection is a rare complication, an association between pregnancy and aortic dissection has been reported even in the absence of preconception aortic root dilatation...
  21. ncbi request reprint Changes in fetal position during labor and their association with epidural analgesia
    Carolyn F Weiniger
    Obstet Gynecol 106:642; author reply 642. 2005