Y Sherer

Summary

Country: Israel

Publications

  1. ncbi request reprint Safety of intravenous immunoglobulin (IVIG) therapy
    Uriel Katz
    Center for Autoimmune Diseases, Department of Internal Medicine B, The Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
    Autoimmun Rev 6:257-9. 2007
  2. doi request reprint Cutting edge issues in autoimmunity
    Yaniv Sherer
    Department of Medicine B, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Israel
    Clin Rev Allergy Immunol 34:275-8. 2008
  3. ncbi request reprint Transient polycythemia and multi-organ failure due to acute alcohol ingestion
    J Mishal
    Department of Medicine B, Barzilai Medical Center, Ashkelon, Israel
    Ann Hematol 79:596-7. 2000
  4. ncbi request reprint Huge renal arteriovenous malformation mimicking a simple para-pelvic cyst
    J Mishal
    Department of Medicine B, Barzilai Medical Center, Ashkelon, Israel
    Urol Int 66:49-50. 2001
  5. ncbi request reprint Successful pregnancy outcome in a patient with Gaucher's disease and antiphospholipid syndrome
    Y Sherer
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Israel
    Ann Hematol 81:161-3. 2002
  6. ncbi request reprint Coronary artery disease but not coronary calcification is associated with elevated levels of cardiolipin, beta-2-glycoprotein-I, and oxidized LDL antibodies
    Y Sherer
    Department of Medicine 'B' and Center of Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel
    Cardiology 95:20-4. 2001
  7. doi request reprint Common infectious agents prevalence in antiphospholipid syndrome
    H Zinger
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Lupus 18:1149-53. 2009
  8. ncbi request reprint Antiphospholipid antibody levels in intravenous immunoglobulin (IVIg) preparations
    Y Sherer
    Department of Medicine 'B' and Center of Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel
    Lupus 10:568-70. 2001
  9. doi request reprint Infectious antibodies in systemic lupus erythematosus patients
    Y Berkun
    Safra Children Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Lupus 18:1129-35. 2009
  10. ncbi request reprint Induction and treatment of the antiphospholipid syndrome--lessons from animal models
    Y Shoenfeld
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Eur J Clin Invest 31:736-40. 2001

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Safety of intravenous immunoglobulin (IVIG) therapy
    Uriel Katz
    Center for Autoimmune Diseases, Department of Internal Medicine B, The Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
    Autoimmun Rev 6:257-9. 2007
    ..We conclude that IVIg is a safe therapy when given in a slow infusion rate in well-hydrated patients, better avoiding patients with known risk factors...
  2. doi request reprint Cutting edge issues in autoimmunity
    Yaniv Sherer
    Department of Medicine B, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Israel
    Clin Rev Allergy Immunol 34:275-8. 2008
  3. ncbi request reprint Transient polycythemia and multi-organ failure due to acute alcohol ingestion
    J Mishal
    Department of Medicine B, Barzilai Medical Center, Ashkelon, Israel
    Ann Hematol 79:596-7. 2000
    ..Although the acute dehydrating effects of alcohol are well known, they usually result in an indolent course. This is the first report of recurrent severe polycythemia and multi-organ failure following acute alcohol consumption...
  4. ncbi request reprint Huge renal arteriovenous malformation mimicking a simple para-pelvic cyst
    J Mishal
    Department of Medicine B, Barzilai Medical Center, Ashkelon, Israel
    Urol Int 66:49-50. 2001
    ..We suggest that duplex ultrasound should accompany routine renal ultrasound in order not to miss such cases, especially when the physical examination suggests an intra-abdominal vascular lesion or bleeding...
  5. ncbi request reprint Successful pregnancy outcome in a patient with Gaucher's disease and antiphospholipid syndrome
    Y Sherer
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Israel
    Ann Hematol 81:161-3. 2002
    ..The possible pathogenicity of antiphospholipid antibodies found in the sera of many asymptomatic Gaucher patients should be further clarified...
  6. ncbi request reprint Coronary artery disease but not coronary calcification is associated with elevated levels of cardiolipin, beta-2-glycoprotein-I, and oxidized LDL antibodies
    Y Sherer
    Department of Medicine 'B' and Center of Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel
    Cardiology 95:20-4. 2001
    ..046). CONCLUSION: Anti-CL, beta2GPI and oxLDL antibodies are elevated in coronary heart disease patients regardless of coronary calcification...
  7. doi request reprint Common infectious agents prevalence in antiphospholipid syndrome
    H Zinger
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Lupus 18:1149-53. 2009
    ..e. toxoplasma and rubella, might either be related to the pathogenesis of antiphospholipid syndrome or alternatively to its manifestations...
  8. ncbi request reprint Antiphospholipid antibody levels in intravenous immunoglobulin (IVIg) preparations
    Y Sherer
    Department of Medicine 'B' and Center of Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel
    Lupus 10:568-70. 2001
    ..The absence of abnormal elevated levels of any of these autoantibodies in five different IVIg preparations provides additional evidence for the safety of IVIg use in APS...
  9. doi request reprint Infectious antibodies in systemic lupus erythematosus patients
    Y Berkun
    Safra Children Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Lupus 18:1129-35. 2009
    ..Our data suggest the importance of previous exposure to infectious agents in the induction and the prevention of SLE...
  10. ncbi request reprint Induction and treatment of the antiphospholipid syndrome--lessons from animal models
    Y Shoenfeld
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Eur J Clin Invest 31:736-40. 2001
    ..Experimental induction and treatment of APS largely contributes to our understanding of the disease and to better management of its clinical characteristics...
  11. ncbi request reprint Anti-endothelial cell antibodies (AECA) in systemic sclerosis--increased sensitivity using different endothelial cell substrates and association with other autoantibodies
    Y Renaudineau
    Research Unit of Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Sackler Faculty of Medicine, Tel-Aviv University, Israel
    Autoimmunity 33:171-9. 2001
    ..CONCLUSIONS: Since false-negative AECA may result from lack of expression of various antigens on a specific EC, analysis of AECA in SSc patients requires using several EC types, including microvascular EC...
  12. ncbi request reprint Autoantibodies associated with atherosclerosis
    Y Shoenfeld
    Department of Medicine B and The Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Ann Med 32:37-40. 2000
    ..This manuscript provides a review of autoantibodies directed towards oxidized low-density lipoprotein (oxLDL), cardiolipin, beta2-glycoprotein-I and heat-shock protein 60/65, and their association with human and murine atherosclerosis...
  13. ncbi request reprint Mechanisms of action of the anti-atherogenic effect of magnesium: lessons from a mouse model
    Y Sherer
    Department of Medicine B, and Institute of Lipid and Atherosclerosis Research, Sheba Medical Center, Tel-Hashomer, Israel
    Magnes Res 14:173-9. 2001
    ..Platelets coverage area on extracellular matrix was similar between groups. These results suggest that Mg might affect LDL oxidation, and thus atherogenesis...
  14. pmc The diagnostic utility of anti-cyclic citrullinated peptide antibodies, matrix metalloproteinase-3, rheumatoid factor, erythrocyte sedimentation rate, and C-reactive protein in patients with erosive and non-erosive rheumatoid arthritis
    O Shovman
    Center for Autoimmune Diseases, Department of Medicine B, Sheba Medical Center, Israel
    Clin Dev Immunol 12:197-202. 2005
    ....
  15. pmc Intravenous immunoglobulins in peripheral neuropathy associated with vasculitis
    Y Levy
    Department of Medicine B and the Centre for Autoimmune Diseases, Sheba Medical Centre Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Ann Rheum Dis 62:1221-3. 2003
    ..Peripheral neuropathy is a prominent feature of the systemic and secondary vasculitides. Usually, it is responsive to corticosteroids, but in certain cases it may be resistant to corticosteroid or immunosuppressive treatment, or both...
  16. ncbi request reprint Adverse effects of intravenous immunoglobulin therapy in 56 patients with autoimmune diseases
    Y Sherer
    Department of Medicine 'B' and Research Unit of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer 52621, Israel
    Pharmacology 62:133-7. 2001
    ..Patients who develop adverse effects during the first treatment course may be at increased risk of adverse effects during the subsequent IVIg courses...
  17. ncbi request reprint Transverse myelitis in patients with antiphospholipid antibodies--the importance of early diagnosis and treatment
    Y Sherer
    Department of Medicine B, Sheba Medical Center, Tel Hashomer, 56121 Israel
    Clin Rheumatol 21:207-10. 2002
    ....
  18. ncbi request reprint 10th International Congress on Antiphospholipid Antibodies--summary
    G Zandman-Goddard
    Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Autoimmun Rev 2:79-85. 2003
    ..Researchers from all aspects of medicine attended the meeting, implicating the systemic characteristics of APS. The important breakthroughs are summarized...
  19. ncbi request reprint Thickened carotid artery intima-media in rheumatoid arthritis is associated with elevated anticardiolipin antibodies
    Y Sherer
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Lupus 16:259-64. 2007
    ....
  20. ncbi request reprint Antiphospholipid syndrome, antiphospholipid antibodies, and atherosclerosis
    Y Sherer
    Department of Medicine 'B, Sheba Medical Center, Tel-Hashomer 52621, Israel
    Curr Atheroscler Rep 3:328-33. 2001
    ..This autoimmune aspect of atherosclerosis in the presence or absence of an autoimmune disease suggests benefit from development of immunomodulating therapies...
  21. ncbi request reprint Cytokine levels in various intravenous immunoglobulin (IVIg) preparations
    Y Sherer
    Department of Medicine 'B' and the Research Unit of Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel
    Hum Antibodies 10:51-3. 2001
    ..Hence, modulation of cytokine levels following IVIg therapy involves other mechanisms such as interference with their secretion or cytokine-specific blocking antibodies, rather than direct infusion of cytokines...
  22. ncbi request reprint Autoantibodies to oxidized low-density lipoprotein in coronary artery disease
    Y Sherer
    Department of Medicine B, Sheba Medical Center, Tel-Hashomer, Israel
    Am J Hypertens 14:149-54. 2001
    ..CONCLUSIONS: Although the levels of oxLDL antibodies might be modified in early hypertension, once advanced coronary artery disease has developed the presence of hypertension does not affect anti-oxLDL levels...
  23. ncbi request reprint Comparative clinical study of cefonicid, chloramphenicol, and penicillin in community-acquired pneumonia
    Y Sherer
    Department of Medicine B and Research Unit of Autoimmune Diseases, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Int J Mol Med 2:343-8. 1998
    ..We conclude that since chloramphenicol is as safe as, and much cheaper than cefonicid, this antibiotic agent is not inferior to the others, its usage in older patients with pneumonia should be considered...
  24. pmc Fibrosis regression induced by intravenous gammaglobulin treatment
    H Amital
    Research Unit of Autoimmune Diseases and Department of Medicine B, Sheba Medical Centre, Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, Israel
    Ann Rheum Dis 62:175-7. 2003
    ..To review case histories of patients in whom fibrosis played a significant role in the pathogenesis of their disease, and to determine whether intravenous gammaglobulin (IVIg) contributed to the regression of their fibrotic condition...
  25. ncbi request reprint Anti-prothrombin antibodies cause thrombosis in a novel qualitative ex-vivo animal model
    S Haj-Yahia
    Center for Autoimmune Diseases, Department of Medicine B, Tel Aviv, Israel
    Lupus 12:364-9. 2003
    ..Active immunization with prothrombin or beta2GPI/prothrombin is associated with prothrombotic activity of blood in an ex-vivo model. This is the first direct evidence for thrombus induction by aPT...
  26. ncbi request reprint Epstein-Barr virus and cytomegalovirus in autoimmune diseases: are they truly notorious? A preliminary report
    O Barzilai
    Center for Autoimmune Diseases, Department of Medicine B, Sheba Medical Center, Tel Hashomer, Israel
    Ann N Y Acad Sci 1108:567-77. 2007
    ..Our data support the theory that EBV is notoriously associated with many autoimmune diseases. CMV appears to be associated to autoimmune diseases as well, yet establishing this theory requires further investigation...
  27. ncbi request reprint Two-stage evaluation and intervention program for control of methicillin-resistant Staphylococcus aureus in the hospital setting
    J Mishal
    Department of Medicine B, Barzilai Medical Centre, Ashkelon, Israel
    Scand J Infect Dis 33:498-501. 2001
    ..02) and from 31 to 5 in the intervention departments (p = 0.001). These results provide additional evidence in favor of establishing a program to control MRSA spread...
  28. ncbi request reprint The association of endothelial dysfunction and cardiovascular events in healthy subjects and patients with cardiovascular disease
    Michael Shechter
    Heart Institute, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 9:271-6. 2007
    ..Endothelial dysfunction is recognized as a major factor in the development of atherosclerosis and it has a prognostic value...
  29. doi request reprint Anti-cardiolipin antibodies and endothelial function in patients with coronary artery disease
    Ibrahim Marai
    Heart Institute, Sheba Medical Center, Tel Hashomer, Israel
    Am J Cardiol 101:1094-7. 2008
    ..In conclusion, in accordance with previous reports of an association between aCL and atherosclerosis, patients with cardiovascular disease had endothelial dysfunction and elevated levels of aCL...
  30. ncbi request reprint Physical examination and ECG screening in relation to echocardiography findings in young healthy adults
    Dan Avi Landau
    Aeromedical Center, Israeli Air Force, Tel Hashomer, Israel
    Cardiology 109:202-7. 2008
    ..Our aim was to test whether screening physical examination and ECG influence the rate of abnormal echocardiogarphic findings in young healthy subjects...
  31. ncbi request reprint Tobacco smoking and autoimmune rheumatic diseases
    Michal Harel-Meir
    Department of Medicine B, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Nat Clin Pract Rheumatol 3:707-15. 2007
    ..Further studies, perhaps using animal models, are needed to analyze the exact effect of smoking on each disease separately...
  32. ncbi request reprint Antiphospholipid syndrome (APS): where does it come from?
    Yaniv Sherer
    Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Israel
    Best Pract Res Clin Rheumatol 21:1071-8. 2007
    ..Identification of the epitopes within the beta-2-glycoprotein-I molecule that serves as the target for autoantibodies makes them the target for immunomodulation of the syndrome...
  33. doi request reprint Autoantibody explosion in antiphospholipid syndrome
    Yehuda Shoenfeld
    Department of Medicine B, Sheba Medical Center, Tel Hashomer, Tel Aviv University, Israel
    J Autoimmun 30:74-83. 2008
    ..This autoantibody explosion might be important in early identification of the syndrome and its manifestations...
  34. ncbi request reprint Precocious atherosclerosis in rheumatoid arthritis: role of traditional and disease-related cardiovascular risk factors
    Roberto Gerli
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Ann N Y Acad Sci 1108:372-81. 2007
    ....
  35. ncbi request reprint The mosaic of autoimmunity: genetic factors involved in autoimmune diseases--2008
    Yehuda Shoenfeld
    Department of Medicine B and Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 10:3-7. 2008
  36. ncbi request reprint The mosaic of autoimmunity: hormonal and environmental factors involved in autoimmune diseases--2008
    Yehuda Shoenfeld
    Department of Medicine B and Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 10:8-12. 2008
  37. ncbi request reprint The mosaic of autoimmunity: prediction, autoantibodies, and therapy in autoimmune diseases--2008
    Yehuda Shoenfeld
    Department of Medicine B and Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 10:13-9. 2008
  38. ncbi request reprint Issues in rheumatology and autoimmunity. Preface
    Yaniv Sherer
    Department of Medicine B and Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 10:138. 2008
  39. ncbi request reprint The expanding world of autoimmunity
    Yehuda Shoenfeld
    Dept of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, 52621, Tel Hashomer, Israel
    Trends Immunol 23:278-9. 2002
  40. ncbi request reprint Induction of oral tolerance in experimental antiphospholipid syndrome by feeding with polyclonal immunoglobulins
    Ilan Krause
    Center for Autoimmune Diseases, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Immunol 32:3414-24. 2002
    ..Our results point to a possible application of IVIG in the induction of oral tolerance against various autoimmune diseases...
  41. ncbi request reprint Antiphospholipid antibodies: are they pro-atherogenic or an epiphenomenon of atherosclerosis?
    Yaniv Sherer
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Immunobiology 207:13-6. 2003
    ....
  42. pmc Multiple autoantibodies associated with autoimmune reproductive failure
    Yaniv Sherer
    Department of Medicine B, Sheba Medical Center, Tel Hashomer, Israel
    J Assist Reprod Genet 20:53-7. 2003
    ..Autoimmune factors are involved in some of the cases of reproductive failure. The aim of this paper is to discuss the association between autoantibodies and reproductive failure...
  43. ncbi request reprint The pathogenic role of anti-thyroglobulin antibody on pregnancy: evidence from an active immunization model in mice
    Shelly Tartakover Matalon
    Center for Autoimmune Diseases, Department of Medicine B, Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv, Israel
    Hum Reprod 18:1094-9. 2003
    ..The aim of this study was to examine whether active immunization with Tg could elicit anti-Tg autoantibodies and reproductive failure without interfering with thyroid function...
  44. ncbi request reprint Immunomodulation for treatment and prevention of atherosclerosis
    Yaniv Sherer
    Department of Medicine B, Sheba Medical Center, Tel Hashomer, 52621, Israel
    Autoimmun Rev 1:21-7. 2002
    ..These include immunosuppression, active immunization, induction of tolerance, administration of intravenous immunoglobulin, gene therapy, cytokine network manipulation and statins...
  45. ncbi request reprint IVIG in autoimmunity and cancer--efficacy versus safety
    Yaniv Sherer
    Department of Medicine B, Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Israel
    Expert Opin Drug Saf 1:153-8. 2002
    ..Overall, IVIG is used in severe medical conditions and it is quite safe. Future research would help to further minimise its associated risks...
  46. ncbi request reprint Endothelial dysfunction: a crystal ball prediction for enhanced cardiovascular risk?
    Michael Shechter
    Isr Med Assoc J 5:736-8. 2003
  47. ncbi request reprint [Accelerated atherosclerosis in rheumatoid arthritis]
    Daniel Shepshelovich
    Department of Medicine B and Center for Autoimmune Diseases, Sheba Medical Center Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Harefuah 144:561-3, 598. 2005
    ..Herein we review and discuss atherosclerosis in rheumatoid arthritis, with special emphasis on clinical presentations, pathogenesis and therapy...
  48. ncbi request reprint [Dermatological manifestations in the antiphospholipid syndrome]
    Gilad Twig
    Department of Medicine B, Sheba Medical Center, Tel Hashomer, Israel
    Harefuah 144:639-41, 675. 2005
    ..The findings entail livedo reticularis, anetoderma, skin necrosis and others. This article discusses their prevalence and their relationships to other clinical manifestations in APS and how to approach them therapeutically...
  49. ncbi request reprint Accelerated atherosclerosis in autoimmune rheumatic diseases
    Yehuda Shoenfeld
    Department of Medicine B, Center for Autoimmune Diseases, Sheba Medical Center Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Circulation 112:3337-47. 2005
  50. ncbi request reprint The infectious etiology of the antiphospholipid syndrome: links between infection and autoimmunity
    Michal Harel
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer 52621, Israel
    Immunobiology 210:743-7. 2005
    ..These findings contribute greatly to the understanding of APS pathogenesis, as well as create new directions for therapy modalities, namely specific peptide toleragens and antimicrobial treatment...
  51. ncbi request reprint Matrix metalloproteinase-9 and autoimmune diseases
    Maya Ram
    Department of Medicine B and Center for Autoimmune Diseases, Sheba Medical Center Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Jerusalem, Israel
    J Clin Immunol 26:299-307. 2006
    ..It is not expressed constantly but rather is induced or suppressed by many regulating molecules. This feature of MMP-9 along with its involvement in disease pathogenesis turns it into a target for therapy of autoimmune diseases...
  52. ncbi request reprint Mechanisms of disease: atherosclerosis in autoimmune diseases
    Yaniv Sherer
    Department of Medicine B and of the Center for Autoimmune Diseases at Sheba Medical Center, Tel Hashomer, Israel
    Nat Clin Pract Rheumatol 2:99-106. 2006
    ..In this article, we briefly review the contribution of autoimmune elements, such as autoreactive lymphocytes and autoantibodies to atherosclerosis and discuss the nature of atherosclerosis in autoimmune rheumatic diseases...
  53. ncbi request reprint Autoantibodies to cardiolipin and beta-2-glycoprotein-I in coronary artery disease patients with and without hypertension
    Yaniv Sherer
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cardiology 97:2-5. 2002
    ..Elevated levels of both antibodies have been reported in hypertension. Nonetheless, there are no data regarding an association between these autoantibodies and hypertension in coronary artery disease...