Gie Ken-Dror

Summary

Country: Israel

Publications

  1. doi request reprint Different effects of apolipoprotein A5 SNPs and haplotypes on triglyceride concentration in three ethnic origins
    Gie Ken-Dror
    Division of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Hum Genet 55:300-7. 2010
  2. pmc A genetic instrument for Mendelian randomization of fibrinogen
    Gie Ken-Dror
    Centre for Cardiovascular Genetics, BHF Laboratories, The Rayne Building, Department of Medicine, Royal Free and University College Medical School, 5 University St, London, WC1E 6JF, UK
    Eur J Epidemiol 27:267-79. 2012
  3. pmc APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men
    Gie Ken-Dror
    Centre for Cardiovascular Genetics, BHF Laboratories, The Rayne Building, Department of Medicine, Royal Free and University College Medical School, 5 University Street, London, United Kingdom
    Mol Med 16:389-99. 2010
  4. doi request reprint The use of haplotypes in the identification of interaction between SNPs
    Gie Ken-Dror
    Centre for Cardiovascular Genetics, BHF Laboratories, Department of Medicine, Royal Free and University College Medical School, London, UK
    Hum Hered 75:44-51. 2013
  5. ncbi request reprint [Measurement and assessment of habitual physical activity in epidemiological studies]
    Gie Ken-Dror
    Department of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, Tel Aviv University
    Harefuah 144:200-5, 230, 229. 2005
  6. doi request reprint The VKORC1 Asp36Tyr variant and VKORC1 haplotype diversity in Ashkenazi and Ethiopian populations
    Sophia Sominsky
    Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Appl Genet 55:163-71. 2014
  7. pmc Free protein S level as a risk factor for coronary heart disease and stroke in a prospective cohort study of healthy United Kingdom men
    Gie Ken-Dror
    Centre for Cardiovascular Genetics, BHF Laboratories, Department of Medicine, Royal Free and University College Medical School, University of London, London, United Kingdom
    Am J Epidemiol 174:958-68. 2011
  8. ncbi request reprint [Development of a Hebrew questionnaire to be used in epidemiological studies to assess physical fitness--validation against sub maximal stress test and predicted VO2max]
    Gie Ken-Dror
    Department of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, Tel Aviv University
    Harefuah 143:566-72, 623. 2004
  9. ncbi request reprint A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance
    Ronen Loebstein
    Institute of Clinical Pharmacology and Toxicology, Sheba Medical Center, Tel Hashomer, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Israel
    Blood 109:2477-80. 2007
  10. pmc The effect of pro-inflammatory conditioning and/or high glucose on telomere shortening of aging fibroblasts
    Klelia D Salpea
    Centre for Cardiovascular Genetics, Division of Medicine, University College London, London, United Kingdom
    PLoS ONE 8:e73756. 2013

Detail Information

Publications10

  1. doi request reprint Different effects of apolipoprotein A5 SNPs and haplotypes on triglyceride concentration in three ethnic origins
    Gie Ken-Dror
    Division of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Hum Genet 55:300-7. 2010
    ..These results suggest that different SNPs in ApoA5 polymorphisms may be associated with triglyceride concentration and CVD in each of these ethnic origins...
  2. pmc A genetic instrument for Mendelian randomization of fibrinogen
    Gie Ken-Dror
    Centre for Cardiovascular Genetics, BHF Laboratories, The Rayne Building, Department of Medicine, Royal Free and University College Medical School, 5 University St, London, WC1E 6JF, UK
    Eur J Epidemiol 27:267-79. 2012
    ..Thus, a combination of several SNPs will provide a stronger instrument for fibrinogen Mendelian randomization studies...
  3. pmc APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men
    Gie Ken-Dror
    Centre for Cardiovascular Genetics, BHF Laboratories, The Rayne Building, Department of Medicine, Royal Free and University College Medical School, 5 University Street, London, United Kingdom
    Mol Med 16:389-99. 2010
    ..While the common APOE polymorphism explains the majority of the locus genetic determinants of plasma lipid levels, additional SNPs in the APOC1/C2 region may contribute to CHD risk, but these effects require confirmation...
  4. doi request reprint The use of haplotypes in the identification of interaction between SNPs
    Gie Ken-Dror
    Centre for Cardiovascular Genetics, BHF Laboratories, Department of Medicine, Royal Free and University College Medical School, London, UK
    Hum Hered 75:44-51. 2013
    ....
  5. ncbi request reprint [Measurement and assessment of habitual physical activity in epidemiological studies]
    Gie Ken-Dror
    Department of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, Tel Aviv University
    Harefuah 144:200-5, 230, 229. 2005
    ..A self-administered questionnaire must be suited to respondents' ages and education levels. Detailed questionnaires/interviews place a considerable burden on subjects...
  6. doi request reprint The VKORC1 Asp36Tyr variant and VKORC1 haplotype diversity in Ashkenazi and Ethiopian populations
    Sophia Sominsky
    Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Appl Genet 55:163-71. 2014
    ..8 %) but relatively uncommon in the Ethiopian origin (4.5-4.7 %). We discuss the genetic diversity among studied populations and its potential impact on warfarin-dose management in certain populations of African and European origin. ..
  7. pmc Free protein S level as a risk factor for coronary heart disease and stroke in a prospective cohort study of healthy United Kingdom men
    Gie Ken-Dror
    Centre for Cardiovascular Genetics, BHF Laboratories, Department of Medicine, Royal Free and University College Medical School, University of London, London, United Kingdom
    Am J Epidemiol 174:958-68. 2011
    ..The novel finding of increased CHD risk, particularly when CRP and PS levels are high, requires further study...
  8. ncbi request reprint [Development of a Hebrew questionnaire to be used in epidemiological studies to assess physical fitness--validation against sub maximal stress test and predicted VO2max]
    Gie Ken-Dror
    Department of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, Tel Aviv University
    Harefuah 143:566-72, 623. 2004
    ..This instrument can be adapted for the particular studied population, and in terms of accuracy it is both reliable and valid...
  9. ncbi request reprint A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance
    Ronen Loebstein
    Institute of Clinical Pharmacology and Toxicology, Sheba Medical Center, Tel Hashomer, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Israel
    Blood 109:2477-80. 2007
    ..Asp36Tyr was common in Jewish ethnic groups of Ethiopian (15%) and Ashkenazi (4%) origin. We suggest that Asp36Tyr is a new marker of the high end of the warfarin dosing range...
  10. pmc The effect of pro-inflammatory conditioning and/or high glucose on telomere shortening of aging fibroblasts
    Klelia D Salpea
    Centre for Cardiovascular Genetics, Division of Medicine, University College London, London, United Kingdom
    PLoS ONE 8:e73756. 2013
    ..14 PD/day, p<0.001, BSO: 0.11 PD/day, p = 0.006 and IL1B: 0.19 PD/day, p = 0.093 vs...