Dov Hershkovitz

Summary

Country: Israel

Publications

  1. ncbi request reprint Monogenic pigmentary skin disorders: genetics and pathophysiology
    Dov Hershkovitz
    Center for Translational Genetics, Rappaport Institute for Research in the Medical Sciences, Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Isr Med Assoc J 10:713-7. 2008
  2. ncbi request reprint Ondansetron for the prevention of seasickness in susceptible sailors: an evaluation at sea
    Dov Hershkovitz
    Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, Haifa, Israel
    Aviat Space Environ Med 80:643-6. 2009
  3. doi request reprint Intratumor Heterogeneity of KRAS Mutation Status in Pancreatic Ductal Adenocarcinoma Is Associated With Smaller Lesions
    Sima S Nagawkar
    From the B Rappaport Faculty of Medicine, Technion Israel Institute of Technology and Institute of Pathology, Rambam Health Care Campus, Haifa, Israel
    Pancreas 45:876-81. 2016
  4. doi request reprint Vestibular evoked myogenic potentials and habituation to seasickness
    Dror Tal
    Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, IDF Medical Corps, Haifa, Israel Electronic address
    Clin Neurophysiol 124:2445-9. 2013
  5. doi request reprint Subclonality for BRAF Mutation in Papillary Thyroid Carcinoma Is Associated With Earlier Disease Stage
    Alona Finkel
    B Rappaport Faculty of Medicine A F, L L, E P, E S, Technion Israel Institute of Technology, Haifa, Israel Institute of Pathology E Si, T B E Sa, O B I, D H, Rambam Health Care Campus, Haifa, Israel and TICC O B I, D H, Technion Integrative Cancer Center at the Ruth and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    J Clin Endocrinol Metab 101:1407-13. 2016
  6. ncbi request reprint Vestibular evoked myogenic potentials and saccular plasticity in divers
    Haim Lavon
    Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, Israel Defense Forces Medical Corps, Haifa, Israel
    Aviat Space Environ Med 81:103-6. 2010
  7. doi request reprint Normal colon tissue and colon carcinoma show no difference in heparanase promoter methylation
    Yehudit Peerless
    Institute of Pathology, Rambam Health Care Campus, Haifa, Israel
    Exp Mol Pathol 94:309-13. 2013
  8. ncbi request reprint Vestibular evoked myogenic potential threshold and seasickness susceptibility
    Dror Tal
    Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, IDF Medical Corps, Haifa, Israel
    J Vestib Res 16:273-8. 2006
  9. doi request reprint Vestibular evoked myogenic potentials and motion sickness medications
    Dror Tal
    Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, Israel Defense Forces Medical Corps, Haifa, Israel Electronic address
    Clin Neurophysiol 127:2350-4. 2016
  10. pmc Variation in KRAS driver substitution distributions between tumor types is determined by both mutation and natural selection
    Sheli L Ostrow
    TICC, Technion Integrative Cancer Center at the Ruth and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Sci Rep 6:21927. 2016

Collaborators

  • Dror Tal
  • Eli Sprecher
  • Reuven Bergman
  • Yehuda Arieli
  • Pedram Gerami
  • Ronen Bar
  • Ofer Ben-Izhak
  • Edmond Sabo
  • Einav Simon
  • Tova Bick
  • Sima S Nagawkar
  • Elad Prinz
  • Yehudit Peerless
  • Sheli L Ostrow
  • Alona Finkel
  • Tova Hershkovitz
  • Alan Yancovitch
  • Haim Lavon
  • Edna Efrati
  • Talia Shentzer
  • Ruth Hershberg
  • Lior Liba
  • Samah Abu-Funni
  • Avshalom Shenhav
  • Margareta Indelman
  • Margo Whiteford
  • Esra Kiliç
  • Peter Galloway
  • Hela Elkin
  • Avi Shupak
  • Gil Kaminski-Graif

Detail Information

Publications19

  1. ncbi request reprint Monogenic pigmentary skin disorders: genetics and pathophysiology
    Dov Hershkovitz
    Center for Translational Genetics, Rappaport Institute for Research in the Medical Sciences, Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Isr Med Assoc J 10:713-7. 2008
    ..In the present review, we discuss normal skin pigmentation and the genetic underpinning of selected disorders of hypo- and hyperpigmentation...
  2. ncbi request reprint Ondansetron for the prevention of seasickness in susceptible sailors: an evaluation at sea
    Dov Hershkovitz
    Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, Haifa, Israel
    Aviat Space Environ Med 80:643-6. 2009
    ..The purpose of the present study was to evaluate the 5HT3 blocker ondansetron in the prevention of seasickness...
  3. doi request reprint Intratumor Heterogeneity of KRAS Mutation Status in Pancreatic Ductal Adenocarcinoma Is Associated With Smaller Lesions
    Sima S Nagawkar
    From the B Rappaport Faculty of Medicine, Technion Israel Institute of Technology and Institute of Pathology, Rambam Health Care Campus, Haifa, Israel
    Pancreas 45:876-81. 2016
    ....
  4. doi request reprint Vestibular evoked myogenic potentials and habituation to seasickness
    Dror Tal
    Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, IDF Medical Corps, Haifa, Israel Electronic address
    Clin Neurophysiol 124:2445-9. 2013
    ..We used the cVEMP test in a prospective evaluation of susceptibility and habituation to seasickness...
  5. doi request reprint Subclonality for BRAF Mutation in Papillary Thyroid Carcinoma Is Associated With Earlier Disease Stage
    Alona Finkel
    B Rappaport Faculty of Medicine A F, L L, E P, E S, Technion Israel Institute of Technology, Haifa, Israel Institute of Pathology E Si, T B E Sa, O B I, D H, Rambam Health Care Campus, Haifa, Israel and TICC O B I, D H, Technion Integrative Cancer Center at the Ruth and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    J Clin Endocrinol Metab 101:1407-13. 2016
    ..Papillary thyroid carcinoma samples were analyzed for the presence of BRAF mutation status subclonality using computerized morphometry and molecular tools. BRAF mutation subclonality was associated with earlier disease stage. ..
  6. ncbi request reprint Vestibular evoked myogenic potentials and saccular plasticity in divers
    Haim Lavon
    Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, Israel Defense Forces Medical Corps, Haifa, Israel
    Aviat Space Environ Med 81:103-6. 2010
    ..The purpose of the present study was to examine possible changes in the sacculocollic reflex of professional divers and to investigate whether there might be diving-induced adaptation of the saccular response...
  7. doi request reprint Normal colon tissue and colon carcinoma show no difference in heparanase promoter methylation
    Yehudit Peerless
    Institute of Pathology, Rambam Health Care Campus, Haifa, Israel
    Exp Mol Pathol 94:309-13. 2013
    ..One of the regulatory mechanisms of heparanase expression is de-methylation on its promoter. In the present study we evaluated the role of heparanase promoter methylation in colon carcinoma...
  8. ncbi request reprint Vestibular evoked myogenic potential threshold and seasickness susceptibility
    Dror Tal
    Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, IDF Medical Corps, Haifa, Israel
    J Vestib Res 16:273-8. 2006
    ..Theoretically, increased susceptibility to seasickness may be due to a discrepancy between the various neural systems as a result of reduced otolith responses...
  9. doi request reprint Vestibular evoked myogenic potentials and motion sickness medications
    Dror Tal
    Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, Israel Defense Forces Medical Corps, Haifa, Israel Electronic address
    Clin Neurophysiol 127:2350-4. 2016
    ....
  10. pmc Variation in KRAS driver substitution distributions between tumor types is determined by both mutation and natural selection
    Sheli L Ostrow
    TICC, Technion Integrative Cancer Center at the Ruth and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Sci Rep 6:21927. 2016
    ..Fitting with this, we found that driver substitutions that are more favored by natural selection in a specific type of tumor tend to associate with worse clinical outcomes specifically in that type of tumor. ..
  11. doi request reprint A deep penetrating facial congenital melanocytic tumor with bone involvement and ipsilateral eye blindness
    Reuven Bergman
    Departments of Dermatology, Pediatric Oncology, Nuclear Medicine, Ophthalmology, and Pathology, Rambam Health Care Campus and the Ruth and Bruce Rappaport Faculty of Medicine, Haifa, Israel Department of Pathology, Hadassah Medical Center, Jerusalem, Israel Department of Dermatology, Northwestern University School of Medicine, Chicago, IL and Department of Radiology, Rambam Health Care Campus and the Ruth and Bruce Rappaport Faculty of Medicine, Haifa, Israel
    Am J Dermatopathol 37:e5-e11. 2015
    ..An 8.5-year follow-up was uneventful, with spontaneous partial shrinkage of the tumor...
  12. doi request reprint Development of a computerized morphometry application for assessment of the tumor fraction in colon carcinoma tissue samples
    Tova Hershkovitz
    Department of Pediatrics B, B Rappaport Faculty of Medicine, Haifa, Israel
    Appl Immunohistochem Mol Morphol 21:54-8. 2013
    ..In conclusion, we believe that this program can be used for standardizing the evaluation of the tumor cell fraction in colon carcinoma and that its use might aid in making better diagnosis and treatment choices for these patients...
  13. pmc Evidence for the initiation of decompression sickness by exposure to intense underwater sound
    Dror Tal
    Israel Naval Medical Institute, Israel Defense Forces Medical Corps, Haifa, Israel
    J Neurophysiol 114:1521-9. 2015
    ..The study outcome has potential implications for human diving safety and may provide an explanation for the mass stranding of cetaceans purportedly associated with sonar activity. ..
  14. doi request reprint KRAS mutation positive mucinous adenocarcinoma originating in mature ovarian teratoma: case report and review of literature
    Dov Hershkovitz
    Institute of Pathology, Rambam Health Care Campus, Haifa, Israel B Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Pathol Int 63:611-4. 2013
    ....
  15. doi request reprint Novel mutations in GALNT3 causing hyperphosphatemic familial tumoral calcinosis
    Alan Yancovitch
    Center for Translational Genetics, Rappaport Institute for Research in the Medical Sciences, Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    J Bone Miner Metab 29:621-5. 2011
    ..Our data expand the spectrum of known mutations in GALNT3 and contribute to a better understanding of the phenotypic manifestations of mutations in this gene...
  16. doi request reprint Disadhesion of epidermal keratinocytes: a histologic clue to palmoplantar keratodermas caused by DSG1 mutations
    Reuven Bergman
    Department of Dermatology, Rambam Medical Center, Haifa, Israel
    J Am Acad Dermatol 62:107-13. 2010
    ..Recent developments in molecular genetics may lead to re-examination of the histopathology of inherited palmoplantar keratodermas (PPKs) based on more precise groupings of the various entities and syndromes...
  17. pmc Functional characterization of SAMD9, a protein deficient in normophosphatemic familial tumoral calcinosis
    Dov Hershkovitz
    Institute of Pathology, Rambam Health Care Campus, Haifa, Israel
    J Invest Dermatol 131:662-9. 2011
    ..In conclusion, our data indicate that SAMD9, an IFN-γ-responsive protein, interacts with RGL2 to diminish the expression of EGR1, a protein of direct relevance to the pathogenesis of ectopic calcification and inflammation...
  18. doi request reprint A novel mutation in RASA1 causes capillary malformation and limb enlargement
    Dov Hershkovitz
    Department of Dermatology and Laboratory of Molecular Dermatology, Rambam Health Care Campus, Haifa, Israel
    Arch Dermatol Res 300:385-8. 2008
    ..A novel mutation in RASA1 was found to underlie the disease in this case. The present results illustrate the extensive degree of phenotypic heterogeneity associated with deleterious mutations in RASA1...
  19. doi request reprint LNA-based PCR clamping enrichment assay for the identification of KRAS mutations
    Edna Efrati
    Center for Translational Genetics, B Rappaport Institute for Research in the Medical Sciences, Technion Israel Institute of Technology and Rambam Health Care Campus, Haifa, Israel
    Cancer Biomark 8:89-94. 2010
    ..In the present study, we developed a KRAS mutations detection method that is both simple and sensitive...