Deborah T Blumenthal

Summary

Country: Israel

Publications

  1. pmc Familiality in brain tumors
    Deborah T Blumenthal
    Division of Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv 64239, Israel
    Neurology 71:1015-20. 2008
  2. doi request reprint Management of malignant gliomas during pregnancy: a case series
    Deborah T Blumenthal
    Department of Oncology, Neuro Oncology Service, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Cancer 113:3349-54. 2008
  3. ncbi request reprint Assessment of neuropathic pain in cancer patients
    Deborah T Blumenthal
    Oncology Division, Tel Aviv Sourasky Medical Center, 64239 Tel Aviv, Israel
    Curr Pain Headache Rep 13:282-7. 2009
  4. doi request reprint Optimization of DCE-MRI protocol for the assessment of patients with brain tumors
    Moran Artzi
    Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Magn Reson Imaging 34:1242-1247. 2016
  5. doi request reprint Differentiation between treatment-related changes and progressive disease in patients with high grade brain tumors using support vector machine classification based on DCE MRI
    Moran Artzi
    Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, 6 Weizman St, 64239, Tel Aviv, Israel
    J Neurooncol 127:515-24. 2016
  6. doi request reprint Calcification in high grade gliomas treated with bevacizumab
    Deborah T Blumenthal
    Neuro Oncology Service, Tel Aviv Sourasky Medical Center, 6 Weizmann St, 64239, Tel Aviv, Israel
    J Neurooncol 123:283-8. 2015
  7. doi request reprint Human cerebral blood volume measurements using dynamic contrast enhancement in comparison to dynamic susceptibility contrast MRI
    Moran Artzi
    Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, 6 Weizmann St, Tel Aviv, 64239, Israel
    Neuroradiology 57:671-8. 2015
  8. doi request reprint Differentiation between vasogenic-edema versus tumor-infiltrative area in patients with glioblastoma during bevacizumab therapy: a longitudinal MRI study
    Moran Artzi
    Functional Brain Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Electronic address
    Eur J Radiol 83:1250-6. 2014
  9. doi request reprint Automatic multi-modal MR tissue classification for the assessment of response to bevacizumab in patients with glioblastoma
    Gilad Liberman
    Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Eur J Radiol 82:e87-94. 2013
  10. doi request reprint Stereotactic radiosurgery (SRS) in high-grade glioma: judicious selection of small target volumes improves results
    Felix Bokstein
    Neuro Oncology Unit, Tel Aviv Medical Center, Tel Aviv University, Tel Aviv, Israel
    J Neurooncol 126:551-7. 2016

Collaborators

Detail Information

Publications20

  1. pmc Familiality in brain tumors
    Deborah T Blumenthal
    Division of Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv 64239, Israel
    Neurology 71:1015-20. 2008
    ..Familiality in brain tumors is not definitively substantiated...
  2. doi request reprint Management of malignant gliomas during pregnancy: a case series
    Deborah T Blumenthal
    Department of Oncology, Neuro Oncology Service, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Cancer 113:3349-54. 2008
    ..Therefore, the aim of the current article was to describe the outcome of women with malignant gliomas who were exposed to chemotherapy early in the gestation period of their pregnancies...
  3. ncbi request reprint Assessment of neuropathic pain in cancer patients
    Deborah T Blumenthal
    Oncology Division, Tel Aviv Sourasky Medical Center, 64239 Tel Aviv, Israel
    Curr Pain Headache Rep 13:282-7. 2009
    ..Direct and indirect effects of the primary neoplasm need to be considered in the etiology of specific syndromes of mononeuropathies and plexopathies...
  4. doi request reprint Optimization of DCE-MRI protocol for the assessment of patients with brain tumors
    Moran Artzi
    Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Magn Reson Imaging 34:1242-1247. 2016
    ..Lower acquisition time may result in over-estimation of kep when using ETM, and therefore care should be taken using model selection...
  5. doi request reprint Differentiation between treatment-related changes and progressive disease in patients with high grade brain tumors using support vector machine classification based on DCE MRI
    Moran Artzi
    Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, 6 Weizman St, 64239, Tel Aviv, Israel
    J Neurooncol 127:515-24. 2016
    ..Results may have major clinical importance for pre-operative planning, guidance for targeting biopsy, and early prediction of radiological outcomes in patients with high grade brain tumors. ..
  6. doi request reprint Calcification in high grade gliomas treated with bevacizumab
    Deborah T Blumenthal
    Neuro Oncology Service, Tel Aviv Sourasky Medical Center, 6 Weizmann St, 64239, Tel Aviv, Israel
    J Neurooncol 123:283-8. 2015
    ..The phenomenon is increased with anti-angiogenic therapy for brain tumors. Calcification may have significance as a predictor for treatment response. ..
  7. doi request reprint Human cerebral blood volume measurements using dynamic contrast enhancement in comparison to dynamic susceptibility contrast MRI
    Moran Artzi
    Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, 6 Weizmann St, Tel Aviv, 64239, Israel
    Neuroradiology 57:671-8. 2015
    ..The aim of this study was to investigate whether DCE can be used for the measurement of cerebral blood volume in place of DSC for the assessment of patients with brain tumors...
  8. doi request reprint Differentiation between vasogenic-edema versus tumor-infiltrative area in patients with glioblastoma during bevacizumab therapy: a longitudinal MRI study
    Moran Artzi
    Functional Brain Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Electronic address
    Eur J Radiol 83:1250-6. 2014
    ..The aim of this study was to differentiate between vasogenic-edema versus tumor-infiltrative area in GB patients...
  9. doi request reprint Automatic multi-modal MR tissue classification for the assessment of response to bevacizumab in patients with glioblastoma
    Gilad Liberman
    Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Eur J Radiol 82:e87-94. 2013
    ..This study aimed to develop a multi-modal MRI automatic classification method to improve accuracy and efficiency of treatment response assessment in patients with recurrent glioblastoma (GB)...
  10. doi request reprint Stereotactic radiosurgery (SRS) in high-grade glioma: judicious selection of small target volumes improves results
    Felix Bokstein
    Neuro Oncology Unit, Tel Aviv Medical Center, Tel Aviv University, Tel Aviv, Israel
    J Neurooncol 126:551-7. 2016
    ..6 vs. 7.3 months, p = 0.0102). SRS may be considered an effective salvage procedure for selected patients with small volume, recurrent high-grade gliomas. Long-term radiological control was observed in more than 50% of the patients...
  11. doi request reprint Classification of tumor area using combined DCE and DSC MRI in patients with glioblastoma
    Moran Artzi
    Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, 6 Weizman St, 64239, Tel Aviv, Israel
    J Neurooncol 121:349-57. 2015
    ..Tumor area segmentation using DCE and DSC can be used to differentiate between vasogenic edema and infiltrative tumors in patients with GB, which is of major clinical importance in therapy response assessment...
  12. doi request reprint The impact of enrollment in clinical trials on survival of patients with glioblastoma
    Tal Shahar
    Department of Neurosurgery, Tel Aviv Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel
    J Clin Neurosci 19:1530-4. 2012
    ..Thus, enrollment in a clinical study carried a significant survival advantage for patients with glioblastoma, raising practical and ethical issues regarding the quality of care of patients who receive "standard" therapy...
  13. pmc Hemodynamic response imaging: a potential tool for the assessment of angiogenesis in brain tumors
    Dafna Ben Bashat
    Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    PLoS ONE 7:e49416. 2012
    ..Reference values from healthy subjects are presented and preliminary results demonstrate the potential of this method to complement perfusion imaging for the detection and follow up of angiogenesis in patients with brain tumors...
  14. doi request reprint Pembrolizumab: first experience with recurrent primary central nervous system (CNS) tumors
    Deborah T Blumenthal
    Neuro Oncology Service, Division of Oncology, Tel Aviv Sourasky Medical Center, 64239, Tel Aviv, Israel
    J Neurooncol 129:453-60. 2016
    ..In this series of 22 patients with recurrent primary brain tumors, PBL showed no clinical or histologic efficacy. We do not recommend further use of PBL for recurrent PBT unless convincing prospective clinical trial data are published. ..
  15. doi request reprint Regression of intracranial meningioma following treatment with nivolumab: Case report and review of the literature
    Efrat Gelerstein
    Department of Neurosurgery, Tel Aviv Medical Center, Tel Aviv, Israel
    J Clin Neurosci . 2017
    ..This is the first clinical report suggesting that antibodies targeting PD-1 are effective in treating meningioma. It should encourage further research into the use of checkpoint inhibitors in meningioma...
  16. doi request reprint A common sense approach to radiotherapy planning of glioblastoma multiforme situated in the temporal lobe
    Felix Bokstein
    Neuro Oncology Service, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Int J Radiat Oncol Biol Phys 72:900-4. 2008
    ..We hypothesized that by using the temporal bone as the radiation field margin, toxicity could be reduced without compromising tumor control...
  17. doi request reprint Treatment with bevacizumab and irinotecan for recurrent high-grade glial tumors
    Felix Bokstein
    Neuro Oncology Service, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Cancer 112:2267-73. 2008
    ..The objective of this study was to evaluate response rates and tolerability of chemotherapy with bevacizumab and irinotecan in recurrent high-grade gliomas...
  18. ncbi request reprint Clinical utility and treatment outcome of comprehensive genomic profiling in high grade glioma patients
    Deborah T Blumenthal
    Division of Oncology, Neuro Oncology Service, Tel Aviv Sourasky Medical Center, 6 Weizman Street, 64239, Tel Aviv, Israel
    J Neurooncol 130:211-219. 2016
    ..The lack of response suggests that further study of mechanisms of resistance in HGG is warranted before routine use of biologically-targeted agents based on NGS results...
  19. doi request reprint Flashes of light-radiation therapy to the brain
    Deborah T Blumenthal
    Neuro Oncology Service, Oncology Division at the Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Radiother Oncol 116:331-3. 2015
    ..We relate this benign phenomenon to low-dose exposure to the eye fields and postulate that the occurrence is underreported in this treated population. ..
  20. ncbi request reprint Surgical therapies in brain metastasis
    Andrew A Kanner
    Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
    Semin Oncol 34:197-205. 2007
    ..In this review the respective roles of surgery and radiosurgery, patient selection, general prognostic factors and tailoring of optimal surgical management strategies for cerebral metastases are discussed...