Raz Jelinek

Summary

Affiliation: Ben-Gurion University of the Negev
Country: Israel

Publications

  1. ncbi request reprint Rapid colorimetric screening of drug interaction and penetration through lipid barriers
    Marina Katz
    Ilse Katz Center for Meso and Nano Scale Science and Technology, Ben Gurion University, Beer Sheva, 84105, Israel
    Pharm Res 23:580-8. 2006
  2. pmc Rapid chromatic detection of bacteria by use of a new biomimetic polymer sensor
    Liron Silbert
    Department of Chemistry and Ilse Katz Center for Nanotechnology, Ben Gurion University, Beer Sheva 84105, Israel
    Appl Environ Microbiol 72:7339-44. 2006
  3. doi request reprint Pardaxin, a fish toxin peptide interaction with a biomimetic phospholipid/polydiacetylene membrane assay
    Sofiya Kolusheva
    Ilse Katz Center for Meso and Nano Scale Science and Technology, Ben Gurion University, Beer Sheva, 84105, Israel
    Peptides 29:1620-5. 2008
  4. ncbi request reprint Polymerized lipid vesicles as colorimetric biosensors for biotechnological applications
    R Jelinek
    Department of Chemistry, Stadler Minerva Center for Mesoscopic Macromolecular Engineering, Ben Gurion University of the Negev, Beersheba, Israel
    Biotechnol Adv 19:109-18. 2001
  5. ncbi request reprint Membrane binding and permeation by indolicidin analogs studied by a biomimetic lipid/polydiacetylene vesicle assay
    Revital Halevy
    Department of Chemistry and Stadler Minerva Center for Mesoscopic Macromolecular Engineering, Ben Gurion University of the Negev, Beersheva 84105, Israel
    Peptides 24:1753-61. 2003
  6. ncbi request reprint Carbohydrate biosensors
    Raz Jelinek
    Department of Chemistry and Staedler Minerva Center for Mesoscopic Macromolecular Engineering, Ben Gurion University of the Negev, Beersheva 84105, Israel
    Chem Rev 104:5987-6015. 2004
  7. ncbi request reprint Membrane interactions of host-defense peptides studied in model systems
    Raz Jelinek
    Department of Chemistry and Staedler Minerva Center for Mesoscopic, Macromolecular Engineering, Ben Gurion University of the Negev, Beersheva 84105, Israel
    Curr Protein Pept Sci 6:103-14. 2005
  8. pmc Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities
    Or Raifman
    Department of Chemistry, Ben Gurion University, Beer Sheva, Israel
    FEBS J 277:233-43. 2010
  9. pmc N-methyl-substituted fluorescent DAG-indololactone isomers exhibit dramatic differences in membrane interactions and biological activity
    Noga Gal
    Department of Chemistry, Ben Gurion University, Beer Sheva 84105, Israel
    Chembiochem 12:2331-40. 2011
  10. pmc Membrane-surface anchoring of charged diacylglycerol-lactones correlates with biological activities
    Or Raifman
    Department of Chemistry, Ben Gurion University, Beer Sheva 84105, Israel
    Chembiochem 11:2003-9. 2010

Collaborators

Detail Information

Publications67

  1. ncbi request reprint Rapid colorimetric screening of drug interaction and penetration through lipid barriers
    Marina Katz
    Ilse Katz Center for Meso and Nano Scale Science and Technology, Ben Gurion University, Beer Sheva, 84105, Israel
    Pharm Res 23:580-8. 2006
    ....
  2. pmc Rapid chromatic detection of bacteria by use of a new biomimetic polymer sensor
    Liron Silbert
    Department of Chemistry and Ilse Katz Center for Nanotechnology, Ben Gurion University, Beer Sheva 84105, Israel
    Appl Environ Microbiol 72:7339-44. 2006
    ..We demonstrate applications of the new platform for reporting on bacterial contaminations in foods and for screening for bacterial antibiotic resistance...
  3. doi request reprint Pardaxin, a fish toxin peptide interaction with a biomimetic phospholipid/polydiacetylene membrane assay
    Sofiya Kolusheva
    Ilse Katz Center for Meso and Nano Scale Science and Technology, Ben Gurion University, Beer Sheva, 84105, Israel
    Peptides 29:1620-5. 2008
    ....
  4. ncbi request reprint Polymerized lipid vesicles as colorimetric biosensors for biotechnological applications
    R Jelinek
    Department of Chemistry, Stadler Minerva Center for Mesoscopic Macromolecular Engineering, Ben Gurion University of the Negev, Beersheba, Israel
    Biotechnol Adv 19:109-18. 2001
    ..The PDA-based molecular assemblies are robust and can be readily applied to diagnosis of physiological molecules and for rapid screening of chemical and biological libraries, for example, in 96 well-plate platforms...
  5. ncbi request reprint Membrane binding and permeation by indolicidin analogs studied by a biomimetic lipid/polydiacetylene vesicle assay
    Revital Halevy
    Department of Chemistry and Stadler Minerva Center for Mesoscopic Macromolecular Engineering, Ben Gurion University of the Negev, Beersheva 84105, Israel
    Peptides 24:1753-61. 2003
    ..The degree of hemolysis induced by the analogs, on the other hand, correlated to the extent of penetration into the hydrophobic core of the lipid assembly...
  6. ncbi request reprint Carbohydrate biosensors
    Raz Jelinek
    Department of Chemistry and Staedler Minerva Center for Mesoscopic Macromolecular Engineering, Ben Gurion University of the Negev, Beersheva 84105, Israel
    Chem Rev 104:5987-6015. 2004
  7. ncbi request reprint Membrane interactions of host-defense peptides studied in model systems
    Raz Jelinek
    Department of Chemistry and Staedler Minerva Center for Mesoscopic, Macromolecular Engineering, Ben Gurion University of the Negev, Beersheva 84105, Israel
    Curr Protein Pept Sci 6:103-14. 2005
    ..We evaluate the strengths and limitations of the various approaches, and point to future directions in the field...
  8. pmc Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities
    Or Raifman
    Department of Chemistry, Ben Gurion University, Beer Sheva, Israel
    FEBS J 277:233-43. 2010
    ....
  9. pmc N-methyl-substituted fluorescent DAG-indololactone isomers exhibit dramatic differences in membrane interactions and biological activity
    Noga Gal
    Department of Chemistry, Ben Gurion University, Beer Sheva 84105, Israel
    Chembiochem 12:2331-40. 2011
    ..Our analysis shows that seemingly small structural modifications of the hydrophobic regions of these biomimetic PKC effectors contribute to pronounced modulation of membrane interactions of the ligands...
  10. pmc Membrane-surface anchoring of charged diacylglycerol-lactones correlates with biological activities
    Or Raifman
    Department of Chemistry, Ben Gurion University, Beer Sheva 84105, Israel
    Chembiochem 11:2003-9. 2010
    ....
  11. ncbi request reprint Detection and analysis of membrane interactions by a biomimetic colorimetric lipid/polydiacetylene assay
    Shoshana Rozner
    Department of Chemistry and the Stadler Minerva Center for Mesoscopic Macromolecular Engineering, Ben Gurion University of the Negev, Beersheva 84105, Israel
    Anal Biochem 319:96-104. 2003
    ..The colorimetric vesicles can incorporate lipid species from different cellular sources facilitating analysis of the contribution of molecular components to membrane properties and lipid interactions...
  12. ncbi request reprint Investigations of antimicrobial peptides in planar film systems
    Roman Volinsky
    Department of Chemistry, and the Ilse Katz Center for Nanotechnology, Ben Gurion University of the Negev, Beer Sheva 84103, Israel
    Biochim Biophys Acta 1758:1393-407. 2006
    ..Importantly, the data demonstrated that in many cases peptide domains are phase-separated within the phospholipid monolayers, suggesting that this behavior contributes to the biological actions of membrane-active antimicrobial peptides...
  13. doi request reprint Heparin inhibits membrane interactions and lipid-induced fibrillation of a prion amyloidogenic determinant
    Ehud Bazar
    Department of Chemistry, Ben Gurion University of Negev, Beer Sheva 84105, Israel
    Chembiochem 12:761-7. 2011
    ..Our results strongly suggest that the primary effects of GAGs in attenuating amyloid toxicities are due to blocking of membrane interactions of the amyloidogenic proteins rather than modulation of their fibrillation properties...
  14. ncbi request reprint Imaging membrane processes in erythrocyte ghosts by surface fusion of a chromatic polymer
    Elena Shtelman
    Ilse Katz Center for Nanotechnology and Department of Chemistry, Ben Gurion University, Beersheva 84105, Israel
    Anal Biochem 348:151-3. 2006
  15. ncbi request reprint Bilayer localization of membrane-active peptides studied in biomimetic vesicles by visible and fluorescence spectroscopies
    Tanya Sheynis
    Department of Chemistry and the Stadler Minerva Center for Mesoscopic Macromolecular Engineering, Ben Gurion University of the Negev, Beersheva, Israel
    Eur J Biochem 270:4478-87. 2003
    ..The solvent relaxation results suggest that decreasing the lipid fluidity might be an important initial factor contributing to the membrane activity of antimicrobial peptides...
  16. doi request reprint Screening membrane interactions of pesticides by cells decorated with chromatic polymer nanopatches
    Agnieszka Mech
    Ilse Katz Institute for Nanotechnology and Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Chem Res Toxicol 22:90-6. 2009
    ..The chromatic technology facilitates rapid evaluation of membrane activity of pesticide compounds and is capable of distinguishing between toxic effects associated with membrane interactions vs intracellular mechanisms...
  17. ncbi request reprint Biomimetic lipid/polymer colorimetric membranes: molecular and cooperative properties
    Sofiya Kolusheva
    Department of Chemistry and Stadler Minerva Center for Mesoscopic Macromolecular Engineering, Ben Gurion University of the Negev, Beersheva 84105, Israel
    J Lipid Res 44:65-71. 2003
    ....
  18. doi request reprint Poly(methyl methacrylate)-supported polydiacetylene films: unique chromatic transitions and molecular sensing
    Kaviya Parambath Kootery
    Department of Chemistry and Ilse Katz Institute for Nanoscale Science and Technology, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    ACS Appl Mater Interfaces 6:8613-20. 2014
    ..Overall, this study presents a new chromatic PDA film system in which noncovalent interactions between the PMMA substrate and spin-coated PDA give rise to distinct chromatic properties and molecular sensing capabilities...
  19. doi request reprint Lipid-induced calcitonin fibrillation blocks membrane interactions of a peptide antibiotic
    Tania Sheynis
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    J Phys Chem B 114:15530-5. 2010
    ..This phenomenon might point to a role of amyloid fibers in preventing membrane disruption by antibiotic peptides and other toxic species...
  20. doi request reprint Specific mutations alter fibrillation kinetics, fiber morphologies, and membrane interactions of pentapeptides derived from human calcitonin
    Amit Shtainfeld
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Biochemistry 49:5299-307. 2010
    ..This work indicates that the structural and kinetic properties of peptide fibrils as well as lipid interactions of fibrillar species are interrelated and are significantly affected by specific residues within amyloid peptide sequences...
  21. pmc Lipid binding and membrane penetration of polymyxin B derivatives studied in a biomimetic vesicle system
    Marina Katz
    Department of Chemistry and Staedler Minerva Center for Mesoscopic Macromolecular Engineering, Ben Gurion University of the Negev, Beersheva 84105, Israel
    Biochem J 375:405-13. 2003
    ..The data also indicate that the extent of penetration into the lipid bilayer is not related to the overall affinity of the peptides to the membrane...
  22. doi request reprint Lipid bilayers significantly modulate cross-fibrillation of two distinct amyloidogenic peptides
    Noga Gal
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva, Israel 84105
    J Am Chem Soc 135:13582-9. 2013
    ..This work hints that membrane-induced cross-fibrillation of unrelated amyloidogenic peptides might play an insidious role in the molecular pathologies of protein misfolding diseases. ..
  23. pmc Self-assembly and lipid interactions of diacylglycerol lactone derivatives studied at the air/water interface
    Liron Philosof-Mazor
    Department of Chemistry, Ben Gurion University, Beer Sheva 84105, Israel
    Langmuir 24:11043-52. 2008
    ..Moreover, the size and charge of the phospholipid headgroups do not seem to affect DAG-lactone interactions with lipids...
  24. doi request reprint Colorimetric polymer films for predicting lipid interactions and percutaneous adsorption of pharmaceutical formulations
    Izek Ben-Shlush
    Department of Chemistry and Ilse Katz Institute for Nanotechnology, Ben Gurion University of the Negev, Beersheba, Israel
    Pharm Res 25:2815-21. 2008
    ..To develop and demonstrate a rapid and simple colorimetric film assay for evaluating lipid interactions of pharmaceutical compounds and gel formulations...
  25. doi request reprint Lipoprotein interactions with chromatic membranes as a novel marker for oxidative stress-related diseases
    Nirit Hanin-Avraham
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Biochim Biophys Acta 1788:2436-43. 2009
    ....
  26. ncbi request reprint Visualization of membrane processes in living cells by surface-attached chromatic polymer patches
    Zulfiya Orynbayeva
    Ilse Katz Center for Meso and Nano Scale Science and Technology and Department of Chemistry, Ben Gurion University, Beersheva 84105, Israel
    Angew Chem Int Ed Engl 44:1092-6. 2005
  27. doi request reprint Membrane processes and biophysical characterization of living cells decorated with chromatic polydiacetylene vesicles
    Natalie Groysman
    The Ilse Katz Institute of Nanotechnology and Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Biochim Biophys Acta 1778:1335-43. 2008
    ..We demonstrate the use of the polydiacetylene-labeled cells for visualizing and discriminating among different membrane interaction mechanisms of pharmaceutical compounds...
  28. doi request reprint Carbon-Dot/Silver-Nanoparticle Flexible SERS-Active Films
    Susanta Kumar Bhunia
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    ACS Appl Mater Interfaces 8:25637-43. 2016
    ....
  29. pmc Lipid-Bilayer Dynamics Probed by a Carbon Dot-Phospholipid Conjugate
    Sukhendu Nandi
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva, Israel
    Biophys J 110:2016-25. 2016
    ....
  30. ncbi request reprint Membrane interactions and metal ion effects on bilayer permeation of the lipophilic ion modulator DP-109
    Sofiya Kolusheva
    Department of Chemistry, Ben Gurion University, Beer Sheva 84105, Israel
    Biochemistry 44:12077-85. 2005
    ..The ionic gradient effects suggest that the insertion of DP-109 into the membrane may depend on the membrane potential...
  31. doi request reprint Correction: Tuneable light-emitting carbon-dot/polymer flexible films prepared through one-pot synthesis
    Susanta Kumar Bhunia
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Nanoscale . 2017
    ..Correction for 'Tuneable light-emitting carbon-dot/polymer flexible films prepared through one-pot synthesis' by Susanta Kumar Bhunia, et al., Nanoscale, 2016, 8, 3400-3406...
  32. doi request reprint Transparent, conductive, and SERS-active Au nanofiber films assembled on an amphiphilic peptide template
    T P Vinod
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 8410, Israel
    Nanoscale 5:10487-93. 2013
    ....
  33. doi request reprint Toxicity inhibitors protect lipid membranes from disruption by Aβ42
    Ravit Malishev
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    ACS Chem Neurosci 6:1860-9. 2015
    ....
  34. pmc Aggregation modulators interfere with membrane interactions of β2-microglobulin fibrils
    Tania Sheynis
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva, Israel
    Biophys J 105:745-55. 2013
    ....
  35. doi request reprint Membrane interactions and lipid binding of casein oligomers and early aggregates
    Miri Sokolovski
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Biochim Biophys Acta 1778:2341-9. 2008
    ..Overall, this study suggests that lipid interactions play important roles in maintaining the essential physiological functions of caseins in mammalian milk...
  36. ncbi request reprint Microscopic visualization of alamethicin incorporation into model membrane monolayers
    Roman Volinsky
    Ilse Katz Center for Nano and Mesoscience and Technology, Department of Chemistry, and Department of Biotechnology Engineering, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Langmuir 20:11084-91. 2004
    ..In particular, the results demonstrate the use of phospholipid/PDA film assemblies for studying membrane-peptide association and interactions within two-dimensional films...
  37. doi request reprint Biomimetic approaches for studying membrane processes
    Raz Jelinek
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Mol Biosyst 5:811-8. 2009
    ..We have not limited this review to discussion of new "sensors" or "assays"per se, but rather we tried to review new concepts employed for analysis of membrane processes...
  38. ncbi request reprint Amyloid - membrane interactions: experimental approaches and techniques
    Raz Jelinek
    Department of Chemistry, Ben Gurion University, Beer Sheva 84105, Israel
    Curr Protein Pept Sci 11:372-84. 2010
    ....
  39. doi request reprint Colorimetric Polydiacetylene-Aerogel Detector for Volatile Organic Compounds (VOCs)
    Susmita Dolai
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    ACS Appl Mater Interfaces . 2017
    ..Encapsulation of PDA derivatives displaying different headgroups within the aerogel produced distinct VOC-dependent color transformations, forming a PDA-aerogel "artificial nose"...
  40. doi request reprint Correction: Stacking interactions by two Phe side chains stabilize and orient assemblies of even the minimal amphiphilic β-sheet motif
    Shlomo Zarzhitsky
    Avram and Stella Goldstein Goren Department of Biotechnology Engineering, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Chem Commun (Camb) 51:14409. 2015
    ..Correction for 'Stacking interactions by two Phe side chains stabilize and orient assemblies of even the minimal amphiphilic β-sheet motif' by Shlomo Zarzhitsky et al., Chem. Commun., 2015, 51, 3154-3157. ..
  41. doi request reprint Bacoside-A, an anti-amyloid natural substance, inhibits membrane disruption by the amyloidogenic determinant of prion protein through accelerating fibril formation
    Ravit Malishev
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Biochim Biophys Acta 1858:2208-14. 2016
    ..This study suggests that induction of fibril formation and corresponding inhibition of membrane interactions are likely the underlying factors for ameliorating amyloid protein toxicity by bacoside-A. ..
  42. doi request reprint Membrane interactions of ionic liquids: possible determinants for biological activity and toxicity
    Noga Gal
    Department of Chemistry, Ben Gurion University, Beer Sheva 84105, Israel
    Biochim Biophys Acta 1818:2967-74. 2012
    ..This work suggests that tuning membrane interactions of ILs should be an important factor for designing future compounds with benign environmental impact...
  43. doi request reprint Bolaamphiphilic vesicles encapsulating iron oxide nanoparticles: new vehicles for magnetically targeted drug delivery
    Liron Philosof-Mazor
    Department of Chemistry and Ilse Katz Institute of Nanotechnology, Faculty of Natural Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Int J Pharm 450:241-9. 2013
    ..IONP-bolavesicles thus constitute a promising drug delivery platform, potentially targeted to the desired location using external magnetic field...
  44. doi request reprint Imaging Pseudomonas aeruginosa Biofilm Extracellular Polymer Scaffolds with Amphiphilic Carbon Dots
    Margarita Ritenberg
    Department of Chemistry, and Ilse Katz Institute for Nanoscale Science and Technology, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    ACS Chem Biol 11:1265-70. 2016
    ..We also show that the amphiphilic C-dot platform enabled screening of substances disrupting biofilm development, specifically quorum sensing inhibitors. ..
  45. doi request reprint Stacking interactions by two Phe side chains stabilize and orient assemblies of even the minimal amphiphilic β-sheet motif
    Shlomo Zarzhitsky
    Avram and Stella Goldstein Goren Department of Biotechnology Engineering, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Chem Commun (Camb) 51:3154-7. 2015
    ..Monitoring the early stages of Phe-Glu-Phe fibril formation revealed unique angular orientations. Phe-Glu-Phe fibrils were further exploited as adsorbing templates for metal ions. ..
  46. doi request reprint Imaging Cancer Cells Expressing the Folate Receptor with Carbon Dots Produced from Folic Acid
    Susanta Kumar Bhunia
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva, 84105, Israel
    Chembiochem 17:614-9. 2016
    ..The folic acid-derived C-dots were not cytotoxic, and their use in bioimaging applications could aid biological studies of cancer cells, identification of agonists/antagonists, and cancer diagnostics. ..
  47. doi request reprint Colorimetric polymer assay for the diagnosis of plasma lipids atherogenic quality in hypercholesterolemic patients
    Ella Mann
    Faculty of Natural Sciences, The Ilse Katz Institute, Ben Gurion University of the Negev, 84105, Beer Sheva, Israel
    Mol Diagn Ther 19:35-43. 2015
    ..The objective of this study is to develop a simple assay for identifying hypercholesterolemia, and assessing the impact of therapeutic treatments...
  48. ncbi request reprint Structures and mode of membrane interaction of a short alpha helical lytic peptide and its diastereomer determined by NMR, FTIR, and fluorescence spectroscopy
    Ziv Oren
    Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel Department of Chemistry, Ben Gurion University of the Negev, Beersheva, Israel
    Eur J Biochem 269:3869-80. 2002
    ....
  49. doi request reprint Nanostructure synthesis at the solid-water interface: spontaneous assembly and chemical transformations of tellurium nanorods
    T P Vinod
    Department of Chemistry, Ben Gurion University of the Negev, 1 Ben Gurion Avenue, Beer Sheva 84105 Israel, Fax 972 8 6472943
    Chemphyschem 15:3026-31. 2014
    ..We show that the surface-anchored tellurium nanorods can be further transformed in situ into Ag2Te, Cu2Te, and SERS-active Au-Te nanorods. This new approach offers a way to construct functional nanostructures directly on surfaces...
  50. ncbi request reprint Detection of Reactive Oxygen Species by a Carbon-Dot-Ascorbic Acid Hydrogel
    Sagarika Bhattacharya
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Anal Chem . 2016
    ..We demonstrate application of the C-dot-hydrogel for evaluating the efficacy of a chemotherapeutic substance, underscoring the potential of the system for drug screening applications...
  51. doi request reprint Bacterial detection with amphiphilic carbon dots
    Sukhendu Nandi
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Analyst 140:4232-7. 2015
    ..Moreover, bacterial labelling with the amphiphilic CDs enables visualization of physiological processes such as cell division. ..
  52. doi request reprint Membrane analysis with amphiphilic carbon dots
    Sukhendu Nandi
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Chem Commun (Camb) 50:10299-302. 2014
    ..The amphiphilic carbon dots enabled imaging of membrane disruption by the beta-amyloid peptide. ..
  53. doi request reprint Light-Induced Conductivity in a Solution-Processed Film of Polydiacetylene and Perylene Diimide
    Hao Jiang
    Department of Chemistry, Ilse Katz Institute for Nanotechnology, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    J Phys Chem Lett 7:1628-31. 2016
    ..Importantly, the drop-casted diacetylene/PDI film exhibits ultraviolet light-induced conductivity, ascribed to effective transport of charge carriers in the conjugated polymerized network. ..
  54. doi request reprint "Bottom-up" transparent electrodes
    Ahiud Morag
    Department of Chemistry and Ilse Katz Institute for Nanoscale Science and Technology, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    J Colloid Interface Sci 482:267-89. 2016
    ..The current hurdles encountered for broader use of bottom-up strategies along with their significant potential are analyzed. ..
  55. doi request reprint High surface area electrodes by template-free self-assembled hierarchical porous gold architecture
    Ahiud Morag
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 8410501, Israel Ilse Katz Institute for Nanoscale Science and Technology, Ben Gurion University of the Negev, Beer Sheva 8410501, Israel
    J Colloid Interface Sci 472:84-9. 2016
    ..Application of the electrode in a pseudo-capacitor device is presented. ..
  56. doi request reprint Photocatalytic hybrid Au/ZnO nanoparticles assembled through a one-pot method
    Joydeb Manna
    Department of Chemistry and Ilse Katz Institute for Nanoscale Science and Technology, Ben Gurion University of the Negev, Beer Sheva 8410501, Israel
    J Colloid Interface Sci 460:113-8. 2015
    ..We show that the hybrid Au/ZnO nanoparticles exhibited enhanced photocatalytic properties compared to the plain ZnO nanoparticles. ..
  57. doi request reprint Tuneable light-emitting carbon-dot/polymer flexible films prepared through one-pot synthesis
    Susanta Kumar Bhunia
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Nanoscale 8:3400-6. 2016
    ..In particular, we successfully produced films emitting white light with attractive properties (i.e."warm" white light with a high colour rendering index) - a highly sought after goal in optical technologies. ..
  58. doi request reprint Nonplanar conductive surfaces via "bottom-up" nanostructured gold coating
    T P Vinod
    Ilse Katz Institute for Nanoscale Science and Technology and Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 8410, Israel
    ACS Appl Mater Interfaces 6:3341-6. 2014
    ..The technology is simple, inexpensive, and easy to implement for varied polymer surfaces (and other substances), opening the way for practical applications in flexible electronics and related fields. ..
  59. doi request reprint Divergent heparin-induced fibrillation pathways of a prion amyloidogenic determinant
    Ehud Bazar
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Chembiochem 11:1997-2002. 2010
    ..This study clarifies previous conflicting studies, and concludes that GAGs inhibit fibrillation and amyloid toxicity in some cases, and promote amyloidogenesis in others...
  60. ncbi request reprint Interactions of mouse Paneth cell alpha-defensins and alpha-defensin precursors with membranes. Prosegment inhibition of peptide association with biomimetic membranes
    Donald P Satchell
    Department of Pathology, University of California College of Medicine, Irvine 92697 4800, USA
    J Biol Chem 278:13838-46. 2003
    ..Collectively, the results suggest that the prosegment inhibits Crp4 bactericidal activity by blocking peptide-mediated perturbation of target cell membranes, a constraint that is relieved when MMP-7 cleaves the prosegment...
  61. ncbi request reprint Colorimetric detection and fingerprinting of bacteria by glass-supported lipid/polydiacetylene films
    Yogesh Scindia
    Department of Chemistry and the Ilse Katz Center for Nanotechnology, Ben Gurion University, Beer Sheva, Israel 84105
    Langmuir 23:4682-7. 2007
    ..Accordingly, bacterial fingerprinting can be achieved through pattern recognition obtained by recording the chromatic transformations in an array of lipid/PDA films having different lipid components...
  62. ncbi request reprint The human islet amyloid polypeptide forms transient membrane-active prefibrillar assemblies
    Yair Porat
    Department of Molecular Microbiology and Biotechnology, George S Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel
    Biochemistry 42:10971-7. 2003
    ..The implications of these observations are discussed in light of designed fibrillization inhibitors...
  63. ncbi request reprint Glass-supported lipid/polydiacetylene films for colour sensing of membrane-active compounds
    Roman Volinsky
    Department of Chemistry and Ilse Katz Center for Nanotechnology, Ben Gurion University, Beer Sheva 84105, Israel
    Biosens Bioelectron 22:3247-51. 2007
    ..Digital image analysis, in particular, allows quantification of the colourimetric transformations. Detection threshold of micromolar concentration of a membrane-active cytolytic peptide is demonstrated...
  64. ncbi request reprint Color fingerprinting of proteins by calixarenes embedded in lipid/polydiacetylene vesicles
    Sofiya Kolusheva
    Ilse Katz Center for Nanotechnology and Department of Chemistry, Ben Gurion University, Beer Sheva, Israel 84105
    J Am Chem Soc 128:13592-8. 2006
    ..The colorimetric assay constitutes a generic platform for high-sensitivity detection of soluble proteins and for evaluation of protein surface charge distribution...
  65. ncbi request reprint Quantitative interactions between cryptdin-4 amino terminal variants and membranes
    Donald P Satchell
    Department of Pathology, College of Medicine, University of California, Irvine, CA 92697 4800, USA
    Peptides 24:1795-805. 2003
    ..The Crp4 peptide N-terminus affects bactericidal activity modestly, apparently by influencing peptide binding to phospholipid bilayers and subsequent permeabilization of target cell membranes...
  66. ncbi request reprint Selective detection of catecholamines by synthetic receptors embedded in chromatic polydiacetylene vesicles
    Sofiya Kolusheva
    Ilse Katz Center for Nanotechnology and Department of Chemistry, Ben Gurion University, Beer Sheva, Israel 84105
    J Am Chem Soc 127:10000-1. 2005
    ..The chromatic assembly provides a generic route for high sensitivity detection of ligand-receptor interactions...
  67. ncbi request reprint Effect of structural and conformation modifications, including backbone cyclization, of hydrophilic hexapeptides on their intestinal permeability and enzymatic stability
    Shmuel Hess
    Departments of Pharmaceutics and Organic Chemistry, and the Wolfson Centre for Applied Structural Biology, The Hebrew University of Jerusalem, Safra Campus, Jerusalem 91904, Israel
    J Med Chem 50:6201-11. 2007
    ..N- or C-methylation did not enhance the permeability of the linear analogs in this series...