Jonathan Rabinowitz

Summary

Affiliation: Bar-Ilan University
Country: Israel

Publications

  1. doi request reprint Usefulness of interim analyses in portending study results in antipsychotic and antidepressant trials
    J Rabinowitz
    Bar Ilan University, Ramat Gan, Israel Electronic address
    Eur Neuropsychopharmacol 25:1999-2007. 2015
  2. doi request reprint Determinants of antipsychotic response in schizophrenia: implications for practice and future clinical trials
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel 91000
    J Clin Psychiatry 75:e308-16. 2014
  3. doi request reprint Combining efficacy and completion rates with no data imputation: a composite approach with greater sensitivity for the statistical evaluation of active comparisons in antipsychotic trials
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel Electronic address
    Eur Neuropsychopharmacol 24:357-68. 2014
  4. doi request reprint Association of prominent positive and prominent negative symptoms and functional health, well-being, healthcare-related quality of life and family burden: a CATIE analysis
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel Electronic address
    Schizophr Res 150:339-42. 2013
  5. doi request reprint Negative symptoms in schizophrenia--the remarkable impact of inclusion definitions in clinical trials and their consequences
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel Electronic address
    Schizophr Res 150:334-8. 2013
  6. ncbi request reprint Factor analysis of the Cohen-Mansfield Agitation Inventory in three large samples of nursing home patients with dementia and behavioral disturbance
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Am J Geriatr Psychiatry 13:991-8. 2005
  7. ncbi request reprint Treatment of cognitive impairment in early psychosis: a comparison of risperidone and haloperidol in a large long-term trial
    Philip D Harvey
    Bar Ilan University, Ramat Gan, Israel
    Am J Psychiatry 162:1888-95. 2005
  8. ncbi request reprint Premorbid functioning and treatment response in recent-onset schizophrenia
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Br J Psychiatry 189:31-5. 2006
  9. ncbi request reprint Time course for antipsychotic treatment response in first-episode schizophrenia
    Robin Emsley
    Department of Social Work, Bar Ilan University, Ramat Gan, Israel
    Am J Psychiatry 163:743-5. 2006
  10. ncbi request reprint Treating behavioral and psychological symptoms in patients with psychosis of Alzheimer's disease using risperidone
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Int Psychogeriatr 19:227-40. 2007

Detail Information

Publications36

  1. doi request reprint Usefulness of interim analyses in portending study results in antipsychotic and antidepressant trials
    J Rabinowitz
    Bar Ilan University, Ramat Gan, Israel Electronic address
    Eur Neuropsychopharmacol 25:1999-2007. 2015
    ....
  2. doi request reprint Determinants of antipsychotic response in schizophrenia: implications for practice and future clinical trials
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel 91000
    J Clin Psychiatry 75:e308-16. 2014
    ..Response to antipsychotics in schizophrenia is highly variable, and determinants are not well understood or used to design clinical trials...
  3. doi request reprint Combining efficacy and completion rates with no data imputation: a composite approach with greater sensitivity for the statistical evaluation of active comparisons in antipsychotic trials
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel Electronic address
    Eur Neuropsychopharmacol 24:357-68. 2014
    ..Composite was more sensitive to effects of experimental treatment vs. active controls (but not placebo) than LOCF and MMRM thereby increasing study power while answering a more relevant question...
  4. doi request reprint Association of prominent positive and prominent negative symptoms and functional health, well-being, healthcare-related quality of life and family burden: a CATIE analysis
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel Electronic address
    Schizophr Res 150:339-42. 2013
    ..There is an increased interest in evaluating the impact of core symptoms of schizophrenia, both positive and negative, on functioning and burden of disease...
  5. doi request reprint Negative symptoms in schizophrenia--the remarkable impact of inclusion definitions in clinical trials and their consequences
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel Electronic address
    Schizophr Res 150:334-8. 2013
    ..While regulators, drug developers and academics have expressed positions in this regard, the implications of these definitions are not yet tested in large-scale trials and there is no consensus...
  6. ncbi request reprint Factor analysis of the Cohen-Mansfield Agitation Inventory in three large samples of nursing home patients with dementia and behavioral disturbance
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Am J Geriatr Psychiatry 13:991-8. 2005
    ..The authors tested the CMAI factor structure by use of data from three samples of nursing home patients categorized a priori as having at least mild behavioral and psychological symptoms of dementia...
  7. ncbi request reprint Treatment of cognitive impairment in early psychosis: a comparison of risperidone and haloperidol in a large long-term trial
    Philip D Harvey
    Bar Ilan University, Ramat Gan, Israel
    Am J Psychiatry 162:1888-95. 2005
    ..The study was conducted in a large group of patients experiencing their first episode of schizophrenia...
  8. ncbi request reprint Premorbid functioning and treatment response in recent-onset schizophrenia
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Br J Psychiatry 189:31-5. 2006
    ..Investigating the relationship between premorbid functioning and treatment response in schizophrenia is relevant to understanding the illness and predicting treatment outcomes...
  9. ncbi request reprint Time course for antipsychotic treatment response in first-episode schizophrenia
    Robin Emsley
    Department of Social Work, Bar Ilan University, Ramat Gan, Israel
    Am J Psychiatry 163:743-5. 2006
    ..The authors examined early onset of antipsychotic action and early prediction of nonresponse to antipsychotics in patients with first-episode schizophrenia...
  10. ncbi request reprint Treating behavioral and psychological symptoms in patients with psychosis of Alzheimer's disease using risperidone
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Int Psychogeriatr 19:227-40. 2007
    ..To examine the effect of risperidone on specific behavioral and psychological symptoms of dementia (BPSD) among patients with psychosis of Alzheimer's disease (AD)...
  11. ncbi request reprint Revisiting the 5 dimensions of the Positive and Negative Syndrome Scale
    Stephen Z Levine
    Bar Ilan University, Ramat Gan, Israel
    J Clin Psychopharmacol 27:431-6. 2007
    ..This article examines the appropriateness of applying CFA to PANSS data and the dimensionality of the PANSS in a large sample of persons with chronic schizophrenia, schizophreniform disorder, and schizoaffective disorder...
  12. ncbi request reprint The course of schizophrenia: progressive deterioration, amelioration or both?
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Res 91:254-8. 2007
    ..Schizophrenia may follow a course of amelioration, deterioration or stability. It is possible that deterioration at the aggregate level may be due to a sub-group of patients with a tendency to deteriorate...
  13. doi request reprint Real-world premorbid functioning in schizophrenia and affective disorders during the early teenage years: a population-based study of school grades and teacher ratings
    Vardit Zerem Ullman
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Res 136:13-8. 2012
    ..Population-based studies of cognitive and behavioral premorbid functioning in psychotic disorders generally focus on late adolescence in schizophrenia and most are based on IQ test scores...
  14. ncbi request reprint Risperidone and haloperidol in first-episode psychosis: a long-term randomized trial
    Nina Schooler
    Hurwich Professor, Bar Ilan University, Ramat Gan, Israel
    Am J Psychiatry 162:947-53. 2005
    ..Thus, initial treatment of active symptoms and subsequent relapse prevention are central goals of pharmacotherapy. This study compared long-term effectiveness of risperidone versus haloperidol in first-episode psychosis patients...
  15. doi request reprint Treatment response trajectories and their antecedents in recent-onset psychosis: a 2-year prospective study
    Stephen Z Levine
    Bar Ilan University, Ramat Gan, Israel
    J Clin Psychopharmacol 30:446-9. 2010
    ..The extent of heterogeneity in antipsychotic treatment response for over extended period is unclear. This study aimed to quantify treatment response trajectories and their characteristics up to 2 years in recent-onset psychosis...
  16. doi request reprint Negative symptoms have greater impact on functioning than positive symptoms in schizophrenia: analysis of CATIE data
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Res 137:147-50. 2012
    ..This should be further tested in studies where negative symptoms improve without concomitant improvement of other symptoms...
  17. pmc Antecedents and patterns of suicide behavior in first-admission psychosis
    Shelly Bakst
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Bull 36:880-9. 2010
    ..Persons with psychotic illnesses have an increased risk for suicide, especially early in the illness. Sufficient knowledge allowing for early recognition is lacking...
  18. doi request reprint Extent of attaining and maintaining symptom remission by antipsychotic medication in the treatment of chronic schizophrenia: evidence from the CATIE study
    Stephen Z Levine
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Res 133:42-6. 2011
    ..Data on attaining and maintaining symptom remission associated with specific antipsychotic medications are rare and variant...
  19. ncbi request reprint A population based elaboration of the role of age of onset on the course of schizophrenia
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Res 88:96-101. 2006
    ..Despite suggestions that an earlier age of onset and being male confer to a poorer course of schizophrenia, evidence regarding when these effects are most salient appears to be ambiguous...
  20. pmc Dropout rates in randomized clinical trials of antipsychotics: a meta-analysis comparing first- and second-generation drugs and an examination of the role of trial design features
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Bull 35:775-88. 2009
    ..Collectively, dropout rates are lower for second- than first-generation antipsychotic drugs and appear to be partly explained by trial design features thus providing direction for future trial design...
  21. doi request reprint Elaboration on the association between immigration and schizophrenia: a population-based national study disaggregating annual trends, country of origin and sex over 15 years
    Nomi Werbeloff
    Bar Ilan University, Ramat Gan, Israel
    Soc Psychiatry Psychiatr Epidemiol 47:303-11. 2012
    ..This study aims to examine the extent to which immigration acts as a risk factor for schizophrenia, delineated by origin, sex and year, using national population-based data over 15 years...
  22. ncbi request reprint Are patients enrolled in first episode psychosis drug trials representative of patients treated in routine clinical practice?
    Jonathan Rabinowitz
    Department of Social Work, Bar Ilan University, Ramat Gan, Israel
    Schizophr Res 61:149-55. 2003
    ..Thus, it is not clear to what extent results are generalizable to most individuals treated for a psychotic illness who may not be eligible for such trials...
  23. ncbi request reprint The relationship of premorbid functioning to illness course in schizophrenia and psychotic mood disorders during two years following first hospitalization
    Rachel Haim
    Bar Ilan University, Ramat Gan, Israel
    J Nerv Ment Dis 194:791-5. 2006
    ..Consistent with new epidemiological research, early assessment of premorbid functioning could provide an avenue for targeted interventions that might improve outcomes...
  24. ncbi request reprint The premorbid adjustment scale structured interview (PAS-SI): preliminary findings
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Res 90:255-7. 2007
    ..Despite its widespread use there is no published structured interview (SI) schedule and little is known about the reliability of the instrument...
  25. ncbi request reprint To what extent do the PANSS and CGI-S overlap?
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    J Clin Psychopharmacol 26:303-7. 2006
    ..PANSS is the "gold standard" measure of efficacy, but it is not always feasible to use, yet the CGI-S requires validation...
  26. ncbi request reprint Behavioral and psychological symptoms in patients with dementia as a target for pharmacotherapy with risperidone
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    J Clin Psychiatry 65:1329-34. 2004
    ..To examine the effect of risperidone on specific behavioral and psychological symptoms of dementia (BPSD)...
  27. ncbi request reprint Primary care physicians' detection of psychological distress among elderly patients
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Am J Geriatr Psychiatry 13:773-80. 2005
    ..Authors compared rates of psychological distress and physician detection among elderly and non-elderly primary-care patients and examined, among elderly patients, variables associated with distress and physician detection...
  28. pmc A composite approach that includes dropout rates when analyzing efficacy data in clinical trials of antipsychotic medications
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Bull 34:1145-50. 2008
    ..An alternative approach is to test the composite hypothesis of the difference between (a) completion rates and (b) efficacy of complete cases. Studies to date have not applied this relatively new method...
  29. doi request reprint Premorbid functioning and treatment response in recent-onset schizophrenia: prospective study with risperidone long-acting injectable
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    J Clin Psychopharmacol 31:75-81. 2011
    ..7%, 49.3%, 29.6%, and 22.2%; P = 0.006). Good premorbid functioning corresponds with better treatment response in recent-onset psychosis as captured on both clinician and patient-reported measures...
  30. ncbi request reprint Differences in age of first hospitalization for schizophrenia among immigrants and nonimmigrants in a national case registry
    Jonathan Rabinowitz
    Department of Social Work, Bar Ilan University, Ramat Gan, Israel
    Schizophr Bull 28:491-9. 2002
    ..Males had earlier ages at first hospitalization than females. The results suggest that immigration may have a delaying effect on age of first admission and support previous findings regarding gender difference in age of onset...
  31. ncbi request reprint Association between functioning in adolescence prior to first admission for schizophrenia and affective disorders and patterns of hospitalizations thereafter
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Res 73:185-91. 2005
    ..Empirical support for this hypothesis comes primarily from small samples using retrospectively collected data...
  32. doi request reprint School-based obesity prevention programs: a meta-analysis of randomized controlled trials
    Shira Sobol-Goldberg
    Louis and Gabi Weisfeld School of Social Work, Bar Ilan University, Ramat Gan, Israel
    Obesity (Silver Spring) 21:2422-8. 2013
    ..Systematic reviews of studies until 2006 reported a lack of consistency about effectiveness of such programs. Presented is an updated systematic review and meta-analysis...
  33. pmc The association of dropout and outcome in trials of antipsychotic medication and its implications for dealing with missing data
    Jonathan Rabinowitz
    Bar Ilan University, Ramat Gan, Israel
    Schizophr Bull 34:286-91. 2008
    ..We examined whether dropout relates to outcome in clinical trials of antipsychotic medication...
  34. pmc Socioeconomic status at birth is associated with risk of schizophrenia: population-based multilevel study
    Shirli Werner
    School of Social Work, Bar Ilan University, Ramat Gan, 52900, Israel
    Schizophr Bull 33:1373-8. 2007
    ..The aim of the current study was to test the association between individual and community SES at birth and risk of schizophrenia...
  35. ncbi request reprint Perceived need and receipt of outpatient mental health services. Factors affecting access in Israeli HMOs
    Jonathan Rabinowitz
    Department of Social Work, Bar Ilan University, Ramat Gan, Israel
    J Ambul Care Manage 26:260-9. 2003
    ..However, severely limiting the availability of services does reduce the proportion of persons getting care. Implications for regulating insurers are discussed...
  36. ncbi request reprint Perceived patient threat and neuroleptic dosage
    Jonathan Rabinowitz
    School of Social Work, Bar Ilan University, Ramat Gan, Israel
    J Nerv Ment Dis 191:129-30. 2003