Andrew E Hogan
Affiliation: University College Dublin
- Cigarette smoke alters the invariant natural killer T cell function and may inhibit anti-tumor responsesAndrew E Hogan
Obesity Immunology Group, Education and Research Centre, St Vincents University Hospital, UCD, Dublin 4, Ireland
Clin Immunol 140:229-35. 2011..CSE inhibits the upregulation of CD107 but not CD69 or CD56 on iNKT cells. These findings suggest that CSE has a specific effect on iNKT cell anti-tumor responses, which may contribute to the role of smoking in the development of cancer...
- Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitusAndrew E Hogan
Obesity Immunology, Education and Research Centre, St Vincent s University Hospital, University College Dublin, Dublin, Ireland
Diabetologia 57:781-4. 2014..We hypothesised that GLP-1 analogue therapy in individuals with type 2 diabetes mellitus would affect the inflammatory macrophage molecule soluble CD163 (sCD163) and adipocytokine profile...
- Invariant Natural Killer T Cell Deficiency and Functional Impairment in Sleep Apnea: Links to Cancer ComorbidityGadintshware Gaoatswe
Obesity Immunology Group, Education and Research Center, St Vincent s University Hospital, University College Dublin, Dublin, Ireland
Sleep 38:1629-34. 2015..We hypothesized that patients with OSA have low number of circulating invariant natural killer T (iNKT) cells, which may also be functionally impaired. This study aims to evaluate the frequency of circulating iNKT cells in OSA...
- Altered distribution and increased IL-17 production by mucosal-associated invariant T cells in adult and childhood obesityEirin Carolan
Obesity Immunology Research, St Vincent s University Hospital and University College Dublin, Dublin 4, Ireland National Children s Research Centre, Crumlin Children s Hospital, Dublin 12, Ireland
J Immunol 194:5775-80. 2015..The alterations in MAIT cells may be contributing to obesity-related sterile inflammation and insulin resistance...
- The impact of childhood obesity on inflammation, innate immune cell frequency, and metabolic microRNA expressionEirin Carolan
Obesity Immunology Group E C, A E H, M C, G G, J O, D O, Education and Research Centre, St Vincent s University Hospital, University College Dublin, Dublin 4, Ireland National Children s Research Centre E C, A E H, and Department of Diabetes and Endocrinology E C, D C, Our Lady s Children s Hospital Crumlin, Dublin 12, Ireland Department of Endocrinology J O, D O, St Columcille s Hospital, Loughlinstown, Dublin, Ireland and Trinity Biomedical Sciences Institute N F, L A O, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland
J Clin Endocrinol Metab 99:E474-8. 2014..The degree to which these changes occur in childhood obesity is not fully defined...