- The emerging role of metabolic regulation in the functioning of Toll-like receptors and the NOD-like receptor Nlrp3Gillian M Tannahill
School of Biochemistry and Immunology, Trinity College, Dublin, Ireland
FEBS Lett 585:1568-72. 2011..This review will assess recent evidence for these complex interactions and speculate on their importance for innate immunity and inflammation...
- Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetesSeth L Masters
Immunology Research Centre, School of Biochemistry and Immunology, Trinity College, Dublin, Ireland
Nat Immunol 11:897-904. 2010..Our findings identify previously unknown mechanisms in the pathogenesis of type 2 diabetes and treatment of pathology caused by IAPP...