John D Clemens

Summary

Affiliation: International Vaccine Institute

Publications

  1. ncbi Herd immunity conferred by killed oral cholera vaccines in Bangladesh: a reanalysis
    Mohammad Ali
    International Vaccine Institute, Seoul, Korea
    Lancet 366:44-9. 2005
  2. pmc Comparisons of predictors for typhoid and paratyphoid fever in Kolkata, India
    Dipika Sur
    1National Institute of Cholera and Enteric Diseases, Kolkata, India
    BMC Public Health 7:289. 2007
  3. pmc A study of typhoid fever in five Asian countries: disease burden and implications for controls
    R Leon Ochiai
    International Vaccine Institute, Seoul, Republic of Korea
    Bull World Health Organ 86:260-8. 2008
  4. pmc Paperless registration during survey enumerations and large oral cholera mass vaccination in Zanzibar, the United Republic of Tanzania
    Mohammad Ali
    International Vaccine Institute, Kwanak PO Box 14, Seoul, 151 600, Republic of Korea
    Bull World Health Organ 88:556-9. 2010
  5. pmc Schools as potential vaccination venue for vaccines outside regular EPI schedule: results from a school census in Pakistan
    Sajid Bashir Soofi
    Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan
    BMC Res Notes 5:6. 2012
  6. ncbi Dr. John d. Clemens' acceptance speech: 2010 albert B. Sabin gold medal award
    John D Clemens
    International Vaccine Institute, Seoul, Korea
    Hum Vaccin 6:. 2010
  7. pmc Efficacy of a low-cost, inactivated whole-cell oral cholera vaccine: results from 3 years of follow-up of a randomized, controlled trial
    Dipika Sur
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    PLoS Negl Trop Dis 5:e1289. 2011
  8. pmc Decreasing incidence of severe malaria and community-acquired bacteraemia among hospitalized children in Muheza, north-eastern Tanzania, 2006-2010
    George Mtove
    National Institute for Medical Research Amani Centre, Tanga, Tanzania
    Malar J 10:320. 2011
  9. pmc Breastfeeding practices in a cohort of inner-city women: the role of contraindications
    Lucinda England
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Department of Health and Human Services, Bethesda, MD 20895, USA
    BMC Public Health 3:28. 2003
  10. pmc A mass vaccination campaign targeting adults and children to prevent typhoid fever in Hechi; expanding the use of Vi polysaccharide vaccine in southeast China: a cluster-randomized trial
    Jin Yang
    Division of Bacterial Diseases, Guangxi Center for Disease Control, 80 Taoyuan Road, Nanning 530021, Guangxi, China
    BMC Public Health 5:49. 2005

Detail Information

Publications124 found, 100 shown here

  1. ncbi Herd immunity conferred by killed oral cholera vaccines in Bangladesh: a reanalysis
    Mohammad Ali
    International Vaccine Institute, Seoul, Korea
    Lancet 366:44-9. 2005
    ..We reanalysed data from a field trial in Bangladesh to ascertain whether there is evidence of indirect protection from killed oral cholera vaccines...
  2. pmc Comparisons of predictors for typhoid and paratyphoid fever in Kolkata, India
    Dipika Sur
    1National Institute of Cholera and Enteric Diseases, Kolkata, India
    BMC Public Health 7:289. 2007
    ..such as water improvement or vaccination campaigns are implemented for groups of individuals we were interested whether risk factors not only for the individual but for households, neighbourhoods and larger areas can be recognised?..
  3. pmc A study of typhoid fever in five Asian countries: disease burden and implications for controls
    R Leon Ochiai
    International Vaccine Institute, Seoul, Republic of Korea
    Bull World Health Organ 86:260-8. 2008
    ..To inform policy-makers about introduction of preventive interventions against typhoid, including vaccination...
  4. pmc Paperless registration during survey enumerations and large oral cholera mass vaccination in Zanzibar, the United Republic of Tanzania
    Mohammad Ali
    International Vaccine Institute, Kwanak PO Box 14, Seoul, 151 600, Republic of Korea
    Bull World Health Organ 88:556-9. 2010
    ..Field trials require extensive data preparation and complex logistics. The use of personal digital assistants (PDAs) can bypass many of the traditional steps that are necessary in a paper-based data entry system...
  5. pmc Schools as potential vaccination venue for vaccines outside regular EPI schedule: results from a school census in Pakistan
    Sajid Bashir Soofi
    Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan
    BMC Res Notes 5:6. 2012
    ..The administrative staff was requested information on school fee, class enrolment, past history of involvement and willingness of parents to participate in a vaccination campaign...
  6. ncbi Dr. John d. Clemens' acceptance speech: 2010 albert B. Sabin gold medal award
    John D Clemens
    International Vaccine Institute, Seoul, Korea
    Hum Vaccin 6:. 2010
    ..And special thanks to my friend, colleague, and mentor, Jan Holmgren, for his overly generous introduction. ..
  7. pmc Efficacy of a low-cost, inactivated whole-cell oral cholera vaccine: results from 3 years of follow-up of a randomized, controlled trial
    Dipika Sur
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    PLoS Negl Trop Dis 5:e1289. 2011
    ..Killed oral cholera vaccines (OCVs) have been licensed for use in developing countries, but protection conferred by licensed OCVs beyond two years of follow-up has not been demonstrated in randomized, clinical trials...
  8. pmc Decreasing incidence of severe malaria and community-acquired bacteraemia among hospitalized children in Muheza, north-eastern Tanzania, 2006-2010
    George Mtove
    National Institute for Medical Research Amani Centre, Tanga, Tanzania
    Malar J 10:320. 2011
    ..The annual incidence and temporal trend of severe malaria and community-acquired bacteraemia during a four-year period in Muheza, Tanzania was assessed...
  9. pmc Breastfeeding practices in a cohort of inner-city women: the role of contraindications
    Lucinda England
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Department of Health and Human Services, Bethesda, MD 20895, USA
    BMC Public Health 3:28. 2003
    ....
  10. pmc A mass vaccination campaign targeting adults and children to prevent typhoid fever in Hechi; expanding the use of Vi polysaccharide vaccine in southeast China: a cluster-randomized trial
    Jin Yang
    Division of Bacterial Diseases, Guangxi Center for Disease Control, 80 Taoyuan Road, Nanning 530021, Guangxi, China
    BMC Public Health 5:49. 2005
    ....
  11. pmc A hospital-based surveillance for Japanese encephalitis in Bali, Indonesia
    Komang Kari
    Department of Pediatrics, Udayana University School of Medicine, Bali, Indonesia
    BMC Med 4:8. 2006
    ....
  12. pmc The burden of diarrhoea, shigellosis, and cholera in North Jakarta, Indonesia: findings from 24 months surveillance
    Magdarina D Agtini
    National Institute of Health Research and Development, Jakarta Indonesia, Ministry of Health, Jakarta, Indonesia
    BMC Infect Dis 5:89. 2005
    ....
  13. pmc Further evidence for association of hepatitis C infection with parenteral schistosomiasis treatment in Egypt
    Malla R Rao
    Epidemiology Branch, National Institute of Child Health and Human Development, Bethesda, Maryland, USA
    BMC Infect Dis 2:29. 2002
    ..To corroborate this evidence, this study evaluates whether HCV infections clustered within houses in which household members had received parenteral treatment for schistosomiasis...
  14. ncbi Introducing new vaccines into developing countries: obstacles, opportunities and complexities
    John Clemens
    International Vaccine Institute, Seoul, Korea
    Nat Med 11:S12-5. 2005
    ..Development and deployment of new vaccines to prevent infectious diseases in developing countries have therefore become high priorities in the global health agenda...
  15. doi New approaches to the assessment of vaccine herd protection in clinical trials
    John Clemens
    International Vaccine Institute, Kwanak gu, Seoul, South Korea
    Lancet Infect Dis 11:482-7. 2011
    ..Here we discuss the use of these designs, which can generate an improved evidence base at an early stage for making decisions about the introduction of new vaccines...
  16. ncbi Development of pathogenicity-driven definitions of outcomes for a field trial of a killed oral vaccine against enterotoxigenic Escherichia coli in Egypt: application of an evidence-based method
    John Clemens
    International Vaccine Institute, Seoul, Korea
    J Infect Dis 189:2299-307. 2004
    ....
  17. pmc Evaluation of vaccines against enteric infections: a clinical and public health research agenda for developing countries
    John Clemens
    International Vaccine Institute, Seoul, Korea
    Philos Trans R Soc Lond B Biol Sci 366:2799-805. 2011
    ....
  18. ncbi Thinking downstream to accelerate the introduction of new vaccines for developing countries
    John D Clemens
    The International Vaccine Institute, Seoul National University Campus, Shillim Dong, Seoul, South Korea
    Vaccine 21:S114-5. 2003
    ..In the absence of this background information, even a successful vaccine may risk substantial difficulties and delays in its introduction into programs for the poor in developing countries...
  19. ncbi Translational research to assist policy decisions about introducing new vaccines in developing countries
    John D Clemens
    International Vaccine Institute, Seoul 151 600, Republic of Korea
    J Health Popul Nutr 22:223-31. 2004
    ..The Programme is conducting translational research to accelerate the rational introduction of new vaccines against cholera, shigellosis, and typhoid fever in developing countries affected by these diseases...
  20. ncbi Hib vaccines for all the world's children?
    John Clemens
    International Vaccine Institute, Seoul 151 818, Korea
    Lancet 366:101-3. 2005
  21. doi New-generation vaccines against cholera
    John Clemens
    International Vaccine Institute, Seoul National University Research Park, San 4 8, Nakseongdae dong, Kwanak gu, Seoul 151 919, Korea
    Nat Rev Gastroenterol Hepatol 8:701-10. 2011
    ....
  22. ncbi The use of typhoid vaccines in Asia: the DOMI experience
    R Leon Ochiai
    International Vaccine Institute, Kwanak gu, Seoul, Korea
    Clin Infect Dis 45:S34-8. 2007
    ..The Diseases of the Most Impoverished (DOMI) Program was initiated to provide evidence to decide on the introduction of typhoid vaccines in Asian countries...
  23. doi A cluster-randomized effectiveness trial of Vi typhoid vaccine in India
    Dipika Sur
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    N Engl J Med 361:335-44. 2009
    ..Uncertainties about the protective effect of Vi polysaccharide vaccine in children under the age of 5 years and about the vaccine's effect under programmatic conditions have inhibited its use in developing countries...
  24. doi Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial
    Dipika Sur
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    Lancet 374:1694-702. 2009
    ..To expand the use of this vaccine, it was modified to comply with WHO standards. We assessed the efficacy and safety of this modified vaccine in a population with endemic cholera...
  25. doi 5 year efficacy of a bivalent killed whole-cell oral cholera vaccine in Kolkata, India: a cluster-randomised, double-blind, placebo-controlled trial
    Sujit K Bhattacharya
    National Institute of Cholera and Enteric Diseases, Kolkata, India Indian Council of Medical Research, New Delhi, India
    Lancet Infect Dis 13:1050-6. 2013
    ..We aimed to assess protective efficacy up to 5 years in a slum area of Kolkata, India...
  26. ncbi A multi-country cluster randomized controlled effectiveness evaluation to accelerate the introduction of Vi polysaccharide typhoid vaccine in developing countries in Asia: rationale and design
    Camilo J Acosta
    International Vaccine Institute, Seoul, South Korea
    Trop Med Int Health 10:1219-28. 2005
    ..Preliminary results are presented that determined the final planning of the trial before immunization. Important methodological and practical issues regarding vaccine cluster randomized designs are illustrated...
  27. ncbi Geographic analysis of vaccine uptake in a cluster-randomized controlled trial in Hue, Vietnam
    Mohammad Ali
    International Vaccine Institute, San 4 8, Bongcheon 7 dong, Kwanak Ku, Seoul 151 818, Republic of Korea
    Health Place 13:577-87. 2007
    ..The findings are important for the management of vaccine campaigns during a trial and for interpretation of disease patterns during vaccine-efficacy evaluation...
  28. pmc Clinical, epidemiological, and spatial characteristics of Vibrio parahaemolyticus diarrhea and cholera in the urban slums of Kolkata, India
    Suman Kanungo
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    BMC Public Health 12:830. 2012
    ..cholerae and V. parahaemolyticus from non-coastal areas. We investigated the differences in clinical, epidemiological and spatial characteristics of the two Vibrio species in the urban slums of Kolkata, India...
  29. pmc The high burden of cholera in children: comparison of incidence from endemic areas in Asia and Africa
    Jacqueline L Deen
    International Vaccine Institute, Seoul, Korea
    PLoS Negl Trop Dis 2:e173. 2008
    ..Cholera remains an important public health problem. Yet there are few reliable population-based estimates of laboratory-confirmed cholera incidence in endemic areas around the world...
  30. pmc Spatial risk for gender-specific adult mortality in an area of southern China
    Mohammad Ali
    International Vaccine Institute, Seoul, Korea
    Int J Health Geogr 6:31. 2007
    ..We constructed spatially smoothed risk maps for gender-specific adult mortality in an area of southern China comprising both urban and rural areas and identified ecological factors of gender-specific mortality across societies...
  31. doi Classical RS1 and environmental RS1 elements in Vibrio cholerae O1 El Tor strains harbouring a tandem repeat of CTX prophage: revisiting Mozambique in 2005
    Seon Young Choi
    International Vaccine Institute, Seoul, Republic of Korea
    J Med Microbiol 59:302-8. 2010
    ..New type RS1 elements RS1(cla) and RS1(env), and a CTX(env) with rstR(env) and the classical ctxB were identified on the large chromosome of the Mozambican isolates collected in 2005...
  32. doi Multilocus variable-number tandem repeat analysis of Vibrio cholerae O1 El Tor strains harbouring classical toxin B
    Seon Young Choi
    International Vaccine Institute, Seoul, Republic of Korea
    J Med Microbiol 59:763-9. 2010
    ....
  33. pmc Community participation in two vaccination trials in slums of Kolkata, India: a multi-level analysis
    Mohammad Ali
    International Vaccine Institute, Seoul, Korea
    J Health Popul Nutr 28:450-7. 2010
    ..The results illustrated that participation in the trial was mostly influenced by various individual and community-level factors, which need to be addressed for a successful vaccination campaign...
  34. doi Immune responses following one and two doses of the reformulated, bivalent, killed, whole-cell, oral cholera vaccine among adults and children in Kolkata, India: a randomized, placebo-controlled trial
    Suman Kanungo
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    Vaccine 27:6887-93. 2009
    ..Responses to V. cholerae O139 were less pronounced but followed a similar pattern. We demonstrate that in a cholera-endemic area, the vaccine elicited vibriocidal responses after a single-dose of the vaccine...
  35. ncbi Evaluation of new-generation serologic tests for the diagnosis of typhoid fever: data from a community-based surveillance in Calcutta, India
    Shanta Dutta
    National Institute of Cholera and Enteric Diseases, P 33 CIT Road, Scheme XM, Beliaghata, P O Box 177, Calcutta 700010, India
    Diagn Microbiol Infect Dis 56:359-65. 2006
    ..There is a need for more efficient rapid diagnostic test for typhoid fever especially during the acute stage of the disease. Until then, culture remains the method of choice...
  36. pmc Use of verbal autopsy to determine mortality patterns in an urban slum in Kolkata, India
    Suman Kanungo
    National Institute of Cholera and Enteric Diseases, Kolkata, India
    Bull World Health Organ 88:667-74. 2010
    ..To define mortality patterns in an urban slum in Kolkata, India, in the context of a cholera and typhoid fever project...
  37. pmc Clinical and epidemiological features of typhoid fever in Pemba, Zanzibar: assessment of the performance of the WHO case definitions
    Kamala Thriemer
    International Vaccine Institute, Seoul, Korea
    PLoS ONE 7:e51823. 2012
    ..We therefore investigated the usefulness of clinical signs, WHO case definition and Widal test for the diagnosis of typhoid fever...
  38. pmc Safety of the recombinant cholera toxin B subunit, killed whole-cell (rBS-WC) oral cholera vaccine in pregnancy
    Ramadhan Hashim
    International Vaccine Institute, Seoul, Korea
    PLoS Negl Trop Dis 6:e1743. 2012
    ..Balancing this concern is the known higher risk of cholera and of complications of pregnancy should cholera occur in these women, as well as the lack of expected adverse events from a killed oral bacterial vaccine...
  39. doi Classification of hybrid and altered Vibrio cholerae strains by CTX prophage and RS1 element structure
    Je Hee Lee
    International Vaccine Institute, Seoul 151 919, Republic of Korea
    J Microbiol 47:783-8. 2009
    ..Group II strains harbor RS1 and CTX prophage, which has an E1 Tor type rstR and classical ctxB on the large chromosome...
  40. ncbi The malaria and typhoid fever burden in the slums of Kolkata, India: data from a prospective community-based study
    Dipika Sur
    National Institute of Cholera and Enteric Diseases, P 33 CIT Rd Scheme XM, Beliaghata, Kolkata 700010, India
    Trans R Soc Trop Med Hyg 100:725-33. 2006
    ..Focal interventions to minimise human-vector contact and improved personal hygiene and targeted vaccination campaigns could help to prevent malaria and typhoid fever in this site...
  41. ncbi Isolation of Salmonella enterica subspecies enterica serovar Paratyphi B dT+, or Salmonella Java, from Indonesia and alteration of the d-tartrate fermentation phenotype by disrupting the ORF STM 3356
    Kyung Ho Han
    International Vaccine Institute, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul, 151 818, Republic of Korea
    J Med Microbiol 55:1661-5. 2006
    ..The results show that the dT+ phenotype requires a functional product encoded by STM 3356, and support the use of the PCR-based discrimination method for S. Paratyphi B and S. Java as the standard differentiation method...
  42. ncbi Implementation of good clinical practice guidelines in vaccine trials in developing countries
    Camilo J Acosta
    International Vaccine Institute, Seoul, Republic of Korea
    Vaccine 25:2852-7. 2007
    ..The ICH GCP principles are discussed below within the framework of this recent typhoid fever vaccine study experience...
  43. doi Validity of the estimates of oral cholera vaccine effectiveness derived from the test-negative design
    Mohammad Ali
    International Vaccine Institute, Seoul, Republic of Korea Johns Hopkins Bloomberg School of Public Health, Baltimore, USA Electronic address
    Vaccine 34:479-85. 2016
    ..Its utility for evaluating oral cholera vaccine (OCV) effectiveness is unknown. We examined this method's validity in assessing OCV effectiveness by comparing the results of TND analyses with those of conventional cohort analyses...
  44. pmc Multilocus sequence typing analysis of Shigella flexneri isolates collected in Asian countries
    Seon Young Choi
    1International Vaccine Institute, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul 151 818, Republic of Korea
    J Med Microbiol 56:1460-6. 2007
    ..S. flexneri serotypes 1-5, X and Y were clustered together in a group containing many allelic variants while serotype 6 formed a distinct group, as previously established...
  45. doi Cost-effectiveness of Japanese encephalitis (JE) immunization in Bali, Indonesia
    Wei Liu
    International Vaccine Institute, San 4 8, Bongcheon 7 dong, Kwanak Ku, Seoul 151 818, Republic of Korea
    Vaccine 26:4456-60. 2008
    ..The potential immunization program averted 54 cases, 5 deaths and saved 1,224 disability adjusted life years (DALYs) at a net cost of USD 700 per JE case averted and USD 31 per DALY saved and thus was highly cost-effective...
  46. doi Is HIV infection associated with an increased risk for cholera? Findings from a case-control study in Mozambique
    Lorenz von Seidlein
    International Vaccine Institute, Seoul, Korea
    Trop Med Int Health 13:683-8. 2008
    ..Our aim was to assess the potential association between both diseases...
  47. doi Effectiveness of Vi capsular polysaccharide typhoid vaccine among children: a cluster randomized trial in Karachi, Pakistan
    M Imran Khan
    International Vaccine Institute, Seoul, Republic of Korea
    Vaccine 30:5389-95. 2012
    ..Vaccination strategies are important for prevention, and the Vi capsular polysaccharide (ViCPS) vaccine has been shown to be effective in reducing the burden of typhoid fever...
  48. ncbi Cholera vaccines for the developing world
    Anna Lena Lopez
    International Vaccine Institute, Seoul, Korea
    Hum Vaccin 4:165-9. 2008
    ..We review oral cholera vaccines that are currently available and in the pipeline including the need for policies that will ensure more extensive usage of these vaccines...
  49. pmc Organizational aspects and implementation of data systems in large-scale epidemiological studies in less developed countries
    Mohammad Ali
    International Vaccine Institute, SNU Research Park, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul, Korea
    BMC Public Health 6:86. 2006
    ..Such information provides little assurance that the data are reliable. There are several issues in data management that if not properly practiced may create an unreliable database, and outcomes of this database will be spurious...
  50. pmc Assessment and comparative analysis of a rapid diagnostic test (Tubex®) for the diagnosis of typhoid fever among hospitalized children in rural Tanzania
    Benedikt Ley
    Translational Research Division, International Vaccine Institute, Seoul, Korea
    BMC Infect Dis 11:147. 2011
    ..A rapid diagnostic test for typhoid fever, Tubex®, is commercially available that uses particle separation to detect immunoglobulin M directed towards Salmonella Typhi O9 lipopolysaccharide in sera...
  51. doi Typhoid vaccination: the Asian experience
    Denise DeRoeck
    Social Science Research and Institutional Development, International Vaccine Institute, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul 151 818, Republic of Korea
    Expert Rev Vaccines 7:547-60. 2008
    ..This review also describes recent typhoid Vi vaccine demonstration projects that were conducted in five Asian countries...
  52. doi Assessing different measures of population-level vaccine protection using a case-control study
    Mohammad Ali
    International Vaccine Institute, Seoul, Republic of Korea Johns Hopkins Bloomberg School of Public Health, Baltimore, USA Electronic address
    Vaccine 33:6878-83. 2015
    ..Case-control studies have not been examined for their utility in assessing population-level vaccine protection in individually randomized trials...
  53. doi An overview of cholera vaccines and their public health implications
    Sachin N Desai
    International Vaccine Institute, Seoul, South Korea
    Curr Opin Pediatr 24:85-91. 2012
    ....
  54. pmc The case for reactive mass oral cholera vaccinations
    Rita Reyburn
    International Vaccine Institute IVI, Seoul, Korea
    PLoS Negl Trop Dis 5:e952. 2011
    ..To evaluate the potential benefit of this pivotal change in WHO policy, we used existing data from cholera outbreaks to simulate the number of cholera cases preventable by reactive mass vaccination...
  55. doi Population impact of Vi capsular polysaccharide vaccine
    M Imran Khan
    International Vaccine Institute, Seoul, 151 919, Republic of Korea
    Expert Rev Vaccines 9:485-96. 2010
    ..The large-scale use of this vaccine can yield protective benefits to a larger population and can reduce the epidemiologic and economic burden of typhoid fever in endemic countries...
  56. pmc The Typhoid Fever Surveillance in Africa Program (TSAP): Clinical, Diagnostic, and Epidemiological Methodologies
    Vera von Kalckreuth
    International Vaccine Institute, Seoul, Republic of Korea
    Clin Infect Dis 62:S9-S16. 2016
    ....
  57. pmc Replacing paper data collection forms with electronic data entry in the field: findings from a study of community-acquired bloodstream infections in Pemba, Zanzibar
    Kamala Thriemer
    International Vaccine Institute, SNU Research Park, San 4 8, Nakseongdae dong, Gwanak Gu, Seoul, Republic of Korea 151 600
    BMC Res Notes 5:113. 2012
    ..It is gaining in popularity and has replaced the paper-based data entry system in many studies. We report our experiences with paper- and PDA-based data collection during a fever surveillance study in Pemba Island, Zanzibar, Tanzania...
  58. pmc The burden of invasive bacterial infections in Pemba, Zanzibar
    Kamala Thriemer
    International Vaccine Institute, Seoul, Republic of Korea
    PLoS ONE 7:e30350. 2012
    ..We conducted a surveillance study to determine the leading causes of bloodstream infection in febrile patients seeking treatment at three district hospitals in Pemba Island, Zanzibar, Tanzania, an area with low malaria transmission...
  59. pmc Salmonella paratyphi A rates, Asia
    R Leon Ochiai
    International Vaccine Institute, Kwanak PO Box 14, Seoul, South Korea 151 600
    Emerg Infect Dis 11:1764-6. 2005
    ..Paratyphi A. We compared their incidences by using standardized methods from population-based studies in China, Indonesia, India, and Pakistan...
  60. pmc Field evaluation of a rapid immunochromatographic dipstick test for the diagnosis of cholera in a high-risk population
    Xuan Yi Wang
    The International Vaccine Institute, Seoul, Korea
    BMC Infect Dis 6:17. 2006
    ..Early detection of cholera outbreaks is crucial for the implementation of the most appropriate control strategies...
  61. pmc The use of a computerized database to monitor vaccine safety in Viet Nam
    Mohammad Ali
    International Vaccine Institute, SNU Campus, Seoul, Republic of Korea
    Bull World Health Organ 83:604-10. 2005
    ....
  62. ncbi The role of epidemiology in the introduction of vi polysaccharide typhoid fever vaccines in Asia
    Camilo J Acosta
    International Vaccine Institute, Seoul, Republic of Korea
    J Health Popul Nutr 22:240-5. 2004
    ..Epidemiological studies contribute to all stages of development of vaccine evaluation and introduction...
  63. pmc Evaluation of a rapid dipstick (Crystal VC) for the diagnosis of cholera in Zanzibar and a comparison with previous studies
    Benedikt Ley
    Translational Research Division, International Vaccine Institute, Seoul, Korea
    PLoS ONE 7:e36930. 2012
    ..A rapid diagnostic test (RDT) that can be used by minimally trained staff at treatment centers could potentially improve the reporting and management of cholera outbreaks...
  64. pmc Neighborhood size and local geographic variation of health and social determinants
    Mohammad Ali
    International Vaccine Institute, SNU Research Park, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul, Korea
    Int J Health Geogr 4:12. 2005
    ..Therefore, selecting optimal neigborhood size is essential for understanding disease ecologies. The optimal neighbourhood selection method that is tested in this paper can be useful in health and ecological studies...
  65. ncbi Multidisciplinary studies of disease burden in the Diseases of the Most Impoverished Programme
    Jacqueline L Deen
    International Vaccine Institute, Seoul 151 600, Republic of Korea
    J Health Popul Nutr 22:232-9. 2004
    ..These projects also build in-country capacity in terms of treatment, diagnosis, epidemiology, and data management...
  66. pmc Immune responses to Vi capsular polysaccharide typhoid vaccine in children 2 to 16 years old in Karachi, Pakistan, and Kolkata, India
    R Leon Ochiai
    International Vaccine Institute, Seoul, Republic of Korea
    Clin Vaccine Immunol 21:661-6. 2014
    ..The antibody levels in children who received this vaccine remained higher than those in children who received the control vaccine but were significantly reduced at 2 years of follow-up...
  67. pmc Vibriocidal antibody responses to a bivalent killed whole-cell oral cholera vaccine in a phase III trial in Kolkata, India
    Suman Kanungo
    Department of Epidemiology, National Institute of Cholera and Enteric Diseases, Kolkata, West Bengal, India
    PLoS ONE 9:e96499. 2014
    ..However, the ascertainment of correlates of immunity conferred by any vaccine is a difficult task...
  68. ncbi Factors associated with reported diarrhoea episodes and treatment-seeking in an urban slum of Kolkata, India
    Dipika Sur
    National Institute of Cholera and Enteric Diseases, P 33 CIT Road Scheme XM, Beliaghata, Kolkata 700 010, India
    J Health Popul Nutr 22:130-8. 2004
    ..The findings increase the understanding of the factors and healthcare-use patterns associated with diarrhoea episodes and may assist in developing public-health messages and infrastructure in Kolkata...
  69. pmc Trend and disease burden of bacillary dysentery in China (1991-2000)
    Xuan Yi Wang
    International Vaccine Institute, Seoul, Republic of Korea
    Bull World Health Organ 84:561-8. 2006
    ..We aimed to determine the burden of bacillary dysentery in China, its cross-regional variations, trends in morbidity and mortality, the causative bacterial species and antimicrobial resistance patterns...
  70. ncbi Efficacy of a locally produced, Chinese Vi polysaccharide typhoid fever vaccine during six years of follow-up
    Camilo J Acosta
    International Vaccine Institute, SNU Research Park, San 4 8 Bong Cheon 7 Dong Kwanak Ku, Seoul 151 818, South Korea
    Vaccine 23:5618-23. 2005
    ..These results confirm that this vaccine protects for at least 2 years, and are consistent with the assertion that the vaccine protects for at least 3 years...
  71. ncbi The introduction of new vaccines into developing countries. IV: Global Access Strategies
    Richard T Mahoney
    Pediatric Dengue Vaccine Initiative, International Vaccine Institute, Seoul, Republic of Korea
    Vaccine 25:4003-11. 2007
    ..Appropriately modified, the proposed framework can be applied to the development and introduction of other products in developing countries including drugs, and nutritional and agricultural products...
  72. ncbi Policymakers' views regarding the introduction of new-generation vaccines against typhoid fever, shigellosis and cholera in Asia
    Denise DeRoeck
    International Vaccine Institute, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul 151 818, South Korea
    Vaccine 23:2762-74. 2005
    ....
  73. pmc Evaluation of the Widal tube agglutination test for the diagnosis of typhoid fever among children admitted to a rural hdospital in Tanzania and a comparison with previous studies
    Benedikt Ley
    International Vaccine Institute, Seoul, Korea
    BMC Infect Dis 10:180. 2010
    ..typhi). However, a more rapid, simpler, and cheaper diagnostic method would be very useful especially in developing countries. The Widal test is widely used in Africa but little information exists about its reliability...
  74. ncbi Issues in the design and implementation of vaccine trials in less developed countries
    Jacqueline L Deen
    International Vaccine Institute, Seoul, Korea
    Nat Rev Drug Discov 5:932-40. 2006
    ....
  75. doi Formative research and development of an evidence-based communication strategy: the introduction of Vi typhoid fever vaccine among school-aged children in Karachi, Pakistan
    Alfred Pach
    International Vaccine Institute, Seoul, Republic of Korea
    J Health Commun 18:306-24. 2013
    ..Identification and dissemination of relevant, community-based disease and vaccination information will increase demand and use of vaccination...
  76. doi Strategy, demand, management, and costs of an international cholera vaccine stockpile
    Brian Maskery
    International Vaccine Institute, Seoul, Republic of Korea
    J Infect Dis 208:S15-22. 2013
    ....
  77. ncbi Policymakers' views on dengue fever/dengue haemorrhagic fever and the need for dengue vaccines in four southeast Asian countries
    Denise DeRoeck
    International Vaccine Institute, P O Box 14, Kwanak, 151 600 Seoul, South Korea
    Vaccine 22:121-9. 2003
    ..The results suggest favourable conditions for public and private sector markets for dengue vaccines and the need for creative financing strategies to ensure their accessibility to poor children in dengue-endemic countries...
  78. ncbi Immunization against Japanese encephalitis in China: a policy analysis
    Wei Liu
    International Vaccine Institute, P O Box 14, Kwanak, Seoul 151 600, Republic of Korea
    Vaccine 24:5178-82. 2006
    ....
  79. doi Oral vaccines against cholera
    Sunheang Shin
    International Vaccine Institute, Seoul, South Korea
    Clin Infect Dis 52:1343-9. 2011
    ..The advent of safe and effective, new-generation oral vaccines against cholera has created renewed interest in the use of vaccines as a tool to control cholera...
  80. pmc Cholera outbreaks caused by an altered Vibrio cholerae O1 El Tor biotype strain producing classical cholera toxin B in Vietnam in 2007 to 2008
    Binh Minh Nguyen
    National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
    J Clin Microbiol 47:1568-71. 2009
    ....
  81. ncbi Occurrence of shigellosis in the young and elderly in rural China: results of a 12-month population-based surveillance study
    Xuan Yi Wang
    International Vaccine Institute, Seoul, South Korea
    Am J Trop Med Hyg 73:416-22. 2005
    ..Widespread resistance to antibiotics adds urgency to the development and use of vaccines to control shigellosis...
  82. ncbi Incidence of diarrhea caused by rotavirus infections in rural Zhengding, China: prospective, population-based surveillance
    Xuan Yi Wang
    International Vaccine Institute, Seoul, South Korea
    J Infect Dis 192:S100-5. 2005
    ..Widespread immunization of children against rotavirus before 6 months of age should be considered for the control of rotavirus diarrhea...
  83. doi Modeling spatial heterogeneity of disease risk and evaluation of the impact of vaccination
    Mohammad Ali
    International Vaccine Institute, San 4 8, Bongcheon 7 dong, Kwanak Ku, Seoul 151 818, Republic of Korea
    Vaccine 27:3724-9. 2009
    ..The results of the analyses confirm both hypotheses. The paper also shows how spatial analysis can be used to understand the impact of vaccination when there are spatially heterogeneous disease distributions...
  84. pmc A multicentre study of Shigella diarrhoea in six Asian countries: disease burden, clinical manifestations, and microbiology
    Lorenz von Seidlein
    International Vaccine Institute, Seoul, Korea
    PLoS Med 3:e353. 2006
    ..We conducted a prospective, population-based study in six Asian countries to gain a better understanding of the current disease burden, clinical manifestations, and microbiology of shigellosis in Asia...
  85. pmc Prevalence of Salmonella Excretion in Stool: A Community Survey in 2 Sites, Guinea-Bissau and Senegal
    Justin Im
    International Vaccine Institute, Seoul, Republic of Korea
    Clin Infect Dis 62:S50-5. 2016
    ..A high incidence of Salmonella enterica serovar Typhi and invasive nontyphoidal Salmonella (NTS) infection has been reported in parts of sub-Saharan Africa, yet the prevalence of Salmonella excretion in the general population is unknown...
  86. pmc Physical and chemical characterization and immunologic properties of Salmonella enterica serovar typhi capsular polysaccharide-diphtheria toxoid conjugates
    Changfa Cui
    International Vaccine Institute, SNU Research Park, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul, Korea
    Clin Vaccine Immunol 17:73-9. 2010
    ..Vi-DT was stable under repeated freeze-thaw (20 cycles). We plan to perform clinical evaluation of the safety and immunogenicity of Vi-DT when added to the infant combination vaccines...
  87. ncbi Multilocus sequence typing (MLST) analysis of Vibrio cholerae O1 El Tor isolates from Mozambique that harbour the classical CTX prophage
    Je Hee Lee
    International Vaccine Institute, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul, 151 818, Republic of Korea
    J Med Microbiol 55:165-70. 2006
    ..The possible origin of these isolates and the presence of the tandem repeat of the classical prophage in them implicate the presence of the classical CTX phage...
  88. ncbi Vaccine Protection of Bangladeshi infants and young children against cholera: implications for vaccine deployment and person-to-person transmission
    Mohammad Ali
    International Vaccine Institute, Seoul, Korea
    Pediatr Infect Dis J 27:33-7. 2008
    ..We investigated whether mass immunization of older children and adults can confer herd protection to children too young to be vaccinated...
  89. doi Typhoid vaccine introduction: An evidence-based pilot implementation project in Nepal and Pakistan
    M Imran Khan
    International Vaccine Institute, Seoul, Republic of Korea Electronic address
    Vaccine 33:C62-7. 2015
    ..Supported and conducted by departments of health in Pakistan and Nepal, a school-based typhoid vaccination was found to be safe and feasible. ..
  90. ncbi Antimicrobial treatment for cholera
    Jacqueline L Deen
    International Vaccine Institute, Kwanak, Seoul 151 818, Korea
    Lancet 366:1054-5. 2005
  91. ncbi The vaccine data link in Nha Trang, Vietnam: a progress report on the implementation of a database to detect adverse events related to vaccinations
    Mohammad Ali
    International Vaccine Institute, SNU Campus, Shillim Dong, Kwanak Ku, P O Box 14, Seoul, South Korea
    Vaccine 21:1681-6. 2003
    ..Based on the validation of the data we hope to optimize this model. Once we find the model working it is planned export this vaccine data safety link to other settings of similar economic status...
  92. doi Geographic analysis of shigellosis in Vietnam
    Deok Ryun Kim
    International Vaccine Institute, SNU Research Park, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul, Republic of Korea
    Health Place 14:755-67. 2008
    ..The disease maps can help identify high-risk areas of shigellosis that can be targeted for interventions. This approach may be useful for the selection of populations and the analysis of vaccine trials...
  93. doi Ten years of the Global Alliance for Vaccines and Immunization: challenges and progress
    John Clemens
    International Vaccine Institute, Seoul, South Korea
    Nat Immunol 11:1069-72. 2010
    ..Diseases preventable by underused vaccines cause the death of approximately 3 million children per year. The Global Alliance for Vaccines and Immunization (GAVI) was launched 10 years ago to tackle this appalling situation...
  94. ncbi Putting typhoid vaccination on the global health agenda
    Denise DeRoeck
    International Vaccine Institute, Seoul, Korea
    N Engl J Med 357:1069-71. 2007
  95. ncbi Introductory evaluation of an oral, killed whole cell enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine in Egyptian infants
    Stephen J Savarino
    US Naval Medical Research Unit Number 3, Cairo, Egypt
    Pediatr Infect Dis J 21:322-30. 2002
    ..We conducted the first trial to assess the safety and immunogenicity of an oral, killed enterotoxigenic Escherichia coli plus cholera toxin B-subunit vaccine in children <2 years old...
  96. ncbi Preferences for treatment of diarrhoea and dysentery in Kaengkhoi district, Saraburi province, Thailand
    Seksun Samosornsuk
    Thammasat Univervity, Patum thani, Thailand
    J Health Popul Nutr 22:113-8. 2004
    ....
  97. ncbi A community-based cluster survey on preferences for treatment of diarrhoea and dysentery in Zhengding county, Hebei province, China
    Xuan Yi Wang
    Department of Molecular Virology, Fudan University, Shanghai, China
    J Health Popul Nutr 22:104-12. 2004
    ....
  98. ncbi Healthcare use for diarrhoea and dysentery in actual and hypothetical cases, Nha Trang, Viet Nam
    Linda Kaljee
    University of Maryland Baltimore, School of Medicine, Department of Pediatrics, Baltimore, MD 21201, USA
    J Health Popul Nutr 22:139-49. 2004
    ..Given these healthcare-use patterns, reported rates could significantly underestimate the real disease burden of dysentery and diarrhoea...
  99. ncbi Diarrhoea episodes and treatment-seeking behaviour in a slum area of North Jakarta, Indonesia
    Cyrus H Simanjuntak
    National Institute of Health Research and Development, Ministry of Health, Jakarta, Indonesia
    J Health Popul Nutr 22:119-29. 2004
    ..Individuals from households in the lowest-income group were significantly more likely to attend a PHC for treatment of diarrhoea compared to individuals from households in the middle- and higher-income groups...
  100. ncbi Epidemiology of Shigella-associated diarrhea in rural Egyptian children
    Remon R Abu-Elyazeed
    U S Naval Medical Research Unit No 3, Cairo, Egypt
    Am J Trop Med Hyg 71:367-72. 2004
    ..In conclusion, Shigella-associated diarrhea remains relatively common in Egyptian children and supports the need for additional control measures including vaccine development...
  101. ncbi Coverage and costs of mass immunization of an oral cholera vaccine in Vietnam
    Dinh Thiem Vu
    National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
    J Health Popul Nutr 21:304-8. 2003
    ..89. Mass immunization with this locally-produced oral, killed cholera vaccine was found to be feasible and affordable with attainment of high vaccination coverage...