Arun Sharma

Summary

Country: India

Publications

  1. ncbi request reprint Purification and characterization of a hemoglobin degrading aspartic protease from the malarial parasite Plasmodium vivax
    Arun Sharma
    Malaria Research Centre, 22 Sham Nath Marg, Delhi 110 054, India
    J Biochem 138:71-8. 2005
  2. ncbi request reprint Involvement of caspase-3-like protein in rapid cell death of Xanthomonas
    Satyendra Gautam
    Food Technology Division, Bhabha Atomic Research Centre, Mumbai 400 085, India
    Mol Microbiol 44:393-401. 2002
  3. doi request reprint Stability of lipid constituents in radiation processed fenugreek seeds and turmeric: role of phenolic antioxidants
    Suchandra Chatterjee
    Food Technology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India
    J Agric Food Chem 57:9226-33. 2009
  4. doi request reprint Effect of Withania somnifera (L. Dunal) root as a feed additive on immunological parameters and disease resistance to Aeromonas hydrophila in Labeo rohita (Hamilton) fingerlings
    Arun Sharma
    Department of Fish Health and Environment, College of Fisheries, Central Agricultural University, Tripura 799210, India
    Fish Shellfish Immunol 29:508-12. 2010
  5. ncbi request reprint Stage-specific cytosolic protein kinase C-like activity in human malarial parasite Plasmodium falciparum
    Arun Sharma
    Department of Protein Biochemistry, Malaria Research Centre, 22 Sham Nath Marg, Delhi 110 054, India
    Indian J Biochem Biophys 42:145-51. 2005
  6. ncbi request reprint Parasite killing in Plasmodium vivax malaria by nitric oxide: implication of aspartic protease inhibition
    Arun Sharma
    Malaria Research Centre, 22 Sham Nath Marg, Delhi 110 054, India
    J Biochem 136:329-34. 2004
  7. pmc Determination of nitric oxide metabolites, nitrate and nitrite, in Anopheles culicifacies mosquito midgut and haemolymph by anion exchange high-performance liquid chromatography: plausible mechanism of refractoriness
    Arun Sharma
    Protein Biochemistry Laboratory, National Institute of Malaria Research ICMR, 22 Sham Nath Marg, Delhi 110 054, India
    Malar J 7:71. 2008
  8. pmc Parasite killing in malaria non-vector mosquito Anopheles culicifacies species B: implication of nitric oxide synthase upregulation
    Sonam Vijay
    Protein Biochemistry and Structural Biology Laboratory, National Institute of Malaria Research ICMR, Dwarka, New Delhi, India
    PLoS ONE 6:e18400. 2011
  9. pmc Imperfect duplicate insertions type of mutations in plasmepsin V modulates binding properties of PEXEL motifs of export proteins in Indian Plasmodium vivax
    Manmeet Rawat
    Protein Biochemistry and Structural Biology Division, National Institute of Malaria Research ICMR, Dwarka, New Delhi, India
    PLoS ONE 8:e60077. 2013
  10. ncbi request reprint Role of transtympanic myringoplasty in modern otology
    Gautam Bir Singh
    Department of Otorhinolaryngology and Head and Neck Surgery, Institute of Medical Sciences and Sir Sunderlal Hospital, Banaras Hindu University, Varanasi, Uttar Pradesh, India
    J Otolaryngol 35:408-12. 2006

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Purification and characterization of a hemoglobin degrading aspartic protease from the malarial parasite Plasmodium vivax
    Arun Sharma
    Malaria Research Centre, 22 Sham Nath Marg, Delhi 110 054, India
    J Biochem 138:71-8. 2005
    ..Ca2+ and Mg2+ ions enhance the protease activity, whereas Cu2+ and Hg2+ ions were found to be inhibitory. The pivotal role of aspartic protease in initiating hemoglobin degradation in P. vivax malaria parasite is also demonstrated...
  2. ncbi request reprint Involvement of caspase-3-like protein in rapid cell death of Xanthomonas
    Satyendra Gautam
    Food Technology Division, Bhabha Atomic Research Centre, Mumbai 400 085, India
    Mol Microbiol 44:393-401. 2002
    ..Caspase-negative mutants of XcgAM2 did not display post-exponential RCD. The importance of RCD in Xanthomonas life cycle is not yet clear, however the phenomenon appears to have similarities with eukaryotic apoptosis...
  3. doi request reprint Stability of lipid constituents in radiation processed fenugreek seeds and turmeric: role of phenolic antioxidants
    Suchandra Chatterjee
    Food Technology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India
    J Agric Food Chem 57:9226-33. 2009
    ..The role of phenolic antioxidants in preventing lipid oxidation in the above spices is discussed...
  4. doi request reprint Effect of Withania somnifera (L. Dunal) root as a feed additive on immunological parameters and disease resistance to Aeromonas hydrophila in Labeo rohita (Hamilton) fingerlings
    Arun Sharma
    Department of Fish Health and Environment, College of Fisheries, Central Agricultural University, Tripura 799210, India
    Fish Shellfish Immunol 29:508-12. 2010
    ..hydrophila infection than control. The results suggest that the W. somnifera root powder have a stimulatory effect on immunological parameters and increases disease resistance in L. rohita fingerlings against A. hydrophila infection...
  5. ncbi request reprint Stage-specific cytosolic protein kinase C-like activity in human malarial parasite Plasmodium falciparum
    Arun Sharma
    Department of Protein Biochemistry, Malaria Research Centre, 22 Sham Nath Marg, Delhi 110 054, India
    Indian J Biochem Biophys 42:145-51. 2005
    ..The results suggest that the PKC-like activity is developmentally expressed during the parasitic survival and development...
  6. ncbi request reprint Parasite killing in Plasmodium vivax malaria by nitric oxide: implication of aspartic protease inhibition
    Arun Sharma
    Malaria Research Centre, 22 Sham Nath Marg, Delhi 110 054, India
    J Biochem 136:329-34. 2004
    ..vivax infections for antimalarial chemotherapy and also biochemical adaptations of the malaria parasite for survival in the host erythrocytes with a better understanding of the protease substrate interactions...
  7. pmc Determination of nitric oxide metabolites, nitrate and nitrite, in Anopheles culicifacies mosquito midgut and haemolymph by anion exchange high-performance liquid chromatography: plausible mechanism of refractoriness
    Arun Sharma
    Protein Biochemistry Laboratory, National Institute of Malaria Research ICMR, 22 Sham Nath Marg, Delhi 110 054, India
    Malar J 7:71. 2008
    ..NO metabolites, nitrite (NO2-) and nitrate (NO3-) are produced by the action of an inducible Anopheles culicifacies NO synthase (AcNOS) in mosquito mid-guts and may be central to anti-parasitic arsenal of these mosquitoes...
  8. pmc Parasite killing in malaria non-vector mosquito Anopheles culicifacies species B: implication of nitric oxide synthase upregulation
    Sonam Vijay
    Protein Biochemistry and Structural Biology Laboratory, National Institute of Malaria Research ICMR, Dwarka, New Delhi, India
    PLoS ONE 6:e18400. 2011
    ..Identification of the differences between genes and gene products that may impart refractory phenotype can facilitate development of novel malaria transmission blocking strategies...
  9. pmc Imperfect duplicate insertions type of mutations in plasmepsin V modulates binding properties of PEXEL motifs of export proteins in Indian Plasmodium vivax
    Manmeet Rawat
    Protein Biochemistry and Structural Biology Division, National Institute of Malaria Research ICMR, Dwarka, New Delhi, India
    PLoS ONE 8:e60077. 2013
    ..This study was undertaken to determine P. vivax plasmepsin V Ind (PvPM-V-Ind) PEXEL motif export pathway for pathogenicity-related proteins/antigens export thereby altering plasmodium exportome during erythrocytic stages...
  10. ncbi request reprint Role of transtympanic myringoplasty in modern otology
    Gautam Bir Singh
    Department of Otorhinolaryngology and Head and Neck Surgery, Institute of Medical Sciences and Sir Sunderlal Hospital, Banaras Hindu University, Varanasi, Uttar Pradesh, India
    J Otolaryngol 35:408-12. 2006
    ..This study evaluates the success rate of transtympanic myringoplasty and defines its role in the current era...
  11. ncbi request reprint Management of aural foreign body: an evaluative study in 738 consecutive cases
    Gautam Bir Singh
    Department of ENT and HNS, Institute of Medical Sciences and Sir Sunderlal Hospital, Banaras Hindu University, Varanasi, India
    Am J Otolaryngol 28:87-90. 2007
    ..The purpose of this study is to evaluate the effectiveness of treatment of this emergent problem by medical personnel other than otolaryngologist...
  12. ncbi request reprint Tympanoplasty type I in children--an evaluative study
    Gautam Bir Singh
    Department of ENT and HNS, Institute of Medical Sciences and S S Hospital, BHU, Varanasi, India
    Int J Pediatr Otorhinolaryngol 69:1071-6. 2005
    ..Thus, a prospective study was planned to evaluate the success rate of paediatric tympanoplasty type I and analyse the factors suggested to influence the outcome of the said surgery...
  13. pmc Towards a Proteomic Catalogue and Differential Annotation of Salivary Gland Proteins in Blood Fed Malaria Vector Anopheles culicifacies by Mass Spectrometry
    Ritu Rawal
    Protein Biochemistry and Structural Biology, National Institute of Malaria Research ICMR, Sector 8, Dwarka, New Delhi, India
    PLoS ONE 11:e0161870. 2016
    ....
  14. pmc Annotated differentially expressed salivary proteins of susceptible and insecticide-resistant mosquitoes of Anopheles stephensi
    Sonam Vijay
    Protein Biochemistry and Structural Biology Laboratory, National Institute of Malaria Research ICMR, Sector 8, Dwarka, New Delhi, India
    PLoS ONE 10:e0119666. 2015
    ..These identified proteins may play a role in regulating mosquito biting behavior patterns and may have implications in the development of malaria parasites in resistant mosquitoes during parasite transmission. ..
  15. pmc Mass spectrometry based proteomic analysis of salivary glands of urban malaria vector Anopheles stephensi
    Sonam Vijay
    Protein Biochemistry and Structural Biology Laboratory, National Institute of Malaria Research ICMR, Sector 8, Dwarka, New Delhi 110077, India
    Biomed Res Int 2014:686319. 2014
    ..Our results may serve as basis to provide a putative functional role of proteins in concept of blood feeding, biting behavior, and other aspects of vector-parasite host interactions for parasite development in anopheline mosquitoes. ..
  16. ncbi request reprint Malarial protease inhibitors: potential new chemotherapeutic agents
    Arun Sharma
    Indian Council of Medical Research, National Institute of Malaria Research, 22 Sham Nath Marg, Delhi 110 054, India
    Curr Opin Investig Drugs 8:642-52. 2007
    ..This review summarizes experimental evidence to support the rational design and development of protease inhibitors as potential new antimalarial drugs...
  17. doi request reprint Molecular and phylogenetic analysis of a novel salivary defensin cDNA from malaria vector Anopheles stephensi
    Rajnikant Dixit
    Molecular Biology Unit, National Center for Cell Science, Ganeshkhind, Pune 411007, India
    Acta Trop 106:75-9. 2008
    ..Amino acid sequence similarity and phylogenetic analysis indicated a higher variation in the pre-propeptide region, as compared to the mature defensin peptide, assuring the presence of finely tuned immune responses to counter pathogens...
  18. ncbi request reprint Radiation-induced enhancement of antioxidant contents of soybean (Glycine max Merrill)
    Prasad S Variyar
    Food Technology Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085, India
    J Agric Food Chem 52:3385-8. 2004
    ....
  19. ncbi request reprint Flavoring components of raw monsooned arabica coffee and their changes during radiation processing
    Prasad S Variyar
    Food Technology Division, BARC, Trombay, Mumbai 400 085, India
    J Agric Food Chem 51:7945-50. 2003
    ..A rationale behind the mechanism of monsooning and radiation-induced enhancement of the monsooning process is discussed...
  20. ncbi request reprint Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia
    D Ross Laybutt
    Section of Islet Transplantation and Cell Biology, Joslin Diabetes Center, Boston, Massachusetts, USA
    Diabetes 51:413-23. 2002
    ..In conclusion, beta-cell adaptation to chronic hyperglycemia and, hence, increased insulin demand is accompanied by the induction of protective stress genes that may contribute to the survival of hypertrophied beta-cells...