M F Rahman

Summary

Country: India

Publications

  1. ncbi request reprint Hematological and clinical chemistry changes induced by subchronic dosing of a novel phosphorothionate (RPR-V) in Wistar male and female rats
    M F Rahman
    Biochemical Toxicology, Biology Division, Indian Institute of Chemical Technology, Hyderabad, India
    Drug Chem Toxicol 29:95-110. 2006
  2. ncbi request reprint Genotoxicity assessment in oncology nurses handling anti-neoplastic drugs
    P V Rekhadevi
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 007, Andhra Pradesh, India
    Mutagenesis 22:395-401. 2007
  3. ncbi request reprint Effects of phosphorothionate on the reproductive system of male rats
    I A Khan
    Biology Division, Indian Institute of Chemical Technology, Hyderabad
    J Environ Sci Health B 36:445-56. 2001
  4. doi request reprint In vivo assessment of genotoxic effects of Annona squamosa seed extract in rats
    Paramjit Grover
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 607, Andhra Pradesh, India
    Food Chem Toxicol 47:1964-71. 2009
  5. doi request reprint Oxidative stress induced by aluminum oxide nanomaterials after acute oral treatment in Wistar rats
    P V Prabhakar
    Toxicology Unit, Indian Institute of Chemical Technology, Hyderabad, Andhra Pradesh, India
    J Appl Toxicol 32:436-45. 2012
  6. doi request reprint Genotoxicity evaluation in workers occupationally exposed to lead
    Paramjit Grover
    Biology Division, Indian Institute of Chemical Technology, Hyderabad, Andhra Pradesh, India
    Int J Hyg Environ Health 213:99-106. 2010
  7. ncbi request reprint Evaluation of genetic damage in operating room personnel exposed to anaesthetic gases
    M Chandrasekhar
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500007, Andhra Pradesh, India
    Mutagenesis 21:249-54. 2006
  8. doi request reprint In vivo genotoxicity assessment of aluminium oxide nanomaterials in rat peripheral blood cells using the comet assay and micronucleus test
    A Balasubramanyam
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Andhra Pradesh, India
    Mutagenesis 24:245-51. 2009
  9. ncbi request reprint Evaluation of genetic damage in workers employed in pesticide production utilizing the Comet assay
    Paramjit Grover
    Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 007, Andhra Pradesh, India
    Mutagenesis 18:201-5. 2003
  10. doi request reprint Evaluation of genotoxic effects of oral exposure to aluminum oxide nanomaterials in rat bone marrow
    A Balasubramanyam
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 607, Andhra Pradesh, India
    Mutat Res 676:41-7. 2009

Collaborators

  • M Mahboob
  • Paramjit Grover
  • M K J Siddiqui
  • Kaiser Jamil
  • S P Singh
  • I A Khan
  • J Kaiser
  • P V Rekhadevi
  • A Balasubramanyam
  • N Sailaja
  • S Indu Kumari
  • Utkarsh A Reddy
  • P V Prabhakar
  • M Chandrasekhar
  • Saber M Hussain
  • Rekhadevi Perumalla Venkata
  • K Danadevi
  • Naresh Dumala
  • Srinivas Chinde
  • Shailaja K Rao
  • Bhanuramya M
  • Pasham Rajasekhar Rao
  • K Sandeep
  • Haseeb A Khan
  • G Sankara Rao
  • Sachin B Agawane
  • B Saleha Banu
  • U S N Murty
  • S Misra
  • J P Reddy
  • S A Hussain
  • Saleha B Vuyyuri
  • P N Achar
  • Y R Ahuja

Detail Information

Publications31

  1. ncbi request reprint Hematological and clinical chemistry changes induced by subchronic dosing of a novel phosphorothionate (RPR-V) in Wistar male and female rats
    M F Rahman
    Biochemical Toxicology, Biology Division, Indian Institute of Chemical Technology, Hyderabad, India
    Drug Chem Toxicol 29:95-110. 2006
    ..Alterations in these parameters show toxic stress in the treated animals especially on blood and blood-forming organs...
  2. ncbi request reprint Genotoxicity assessment in oncology nurses handling anti-neoplastic drugs
    P V Rekhadevi
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 007, Andhra Pradesh, India
    Mutagenesis 22:395-401. 2007
    ..This data corroborate the need to maintain safety measures to avoid exposure and the necessity of intervention in the case of exposure when using and handling anti-neoplastic drugs...
  3. ncbi request reprint Effects of phosphorothionate on the reproductive system of male rats
    I A Khan
    Biology Division, Indian Institute of Chemical Technology, Hyderabad
    J Environ Sci Health B 36:445-56. 2001
    ..However, withdrawal studies showed a recovery in testis of rat treated with RPR-V. GST, GSH, GSI, AcP and AkP values were recovered, testosterone levels were also recovered but recovery in testis structure remained at a low profile...
  4. doi request reprint In vivo assessment of genotoxic effects of Annona squamosa seed extract in rats
    Paramjit Grover
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 607, Andhra Pradesh, India
    Food Chem Toxicol 47:1964-71. 2009
    ..Our results warrant careful use of Annona squamosa seed extract as a biopesticide till more tests are carried out...
  5. doi request reprint Oxidative stress induced by aluminum oxide nanomaterials after acute oral treatment in Wistar rats
    P V Prabhakar
    Toxicology Unit, Indian Institute of Chemical Technology, Hyderabad, Andhra Pradesh, India
    J Appl Toxicol 32:436-45. 2012
    ..However, the effect decreased with increase with time after treatment. The histopathological examination showed lesions only in liver with Al₂O₃ nanomaterials at 2000 mg kg⁻¹...
  6. doi request reprint Genotoxicity evaluation in workers occupationally exposed to lead
    Paramjit Grover
    Biology Division, Indian Institute of Chemical Technology, Hyderabad, Andhra Pradesh, India
    Int J Hyg Environ Health 213:99-106. 2010
    ..In view of the observed results, it can be strongly concluded that the workers comprise the risk group and adequate safety, precautionary and preventive measures could only minimize exposure and the related health hazards...
  7. ncbi request reprint Evaluation of genetic damage in operating room personnel exposed to anaesthetic gases
    M Chandrasekhar
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500007, Andhra Pradesh, India
    Mutagenesis 21:249-54. 2006
    ..The results of our study suggest that exposure to waste anaesthetic gases has the potential to cause changes in the human genome...
  8. doi request reprint In vivo genotoxicity assessment of aluminium oxide nanomaterials in rat peripheral blood cells using the comet assay and micronucleus test
    A Balasubramanyam
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Andhra Pradesh, India
    Mutagenesis 24:245-51. 2009
    ..The data indicated that tissue distribution of Al(2)O(3) was size dependent. Our findings suggest that Al(2)O(3) NMs were able to cause size- and dose-dependent genotoxicity in vivo compared to Al(2)O(3)-bulk and control groups...
  9. ncbi request reprint Evaluation of genetic damage in workers employed in pesticide production utilizing the Comet assay
    Paramjit Grover
    Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 007, Andhra Pradesh, India
    Mutagenesis 18:201-5. 2003
    ..The present study suggests that occupational exposure to pesticides and smoking can cause DNA damage. This investigation confirms the sensitivity of the Comet assay...
  10. doi request reprint Evaluation of genotoxic effects of oral exposure to aluminum oxide nanomaterials in rat bone marrow
    A Balasubramanyam
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 607, Andhra Pradesh, India
    Mutat Res 676:41-7. 2009
    ..The results of our study suggest that exposure to Aluminum oxide nanomaterials has the potential to cause genetic damage...
  11. doi request reprint Genetic damage in wood dust-exposed workers
    P V Rekhadevi
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Andhra Pradesh, India
    Mutagenesis 24:59-65. 2009
    ..Antioxidant enzyme levels significantly decreased in the exposed subjects. Our findings indicate enhanced levels of genotoxicity in carpenters. Hence, these workers may have an increased cancer risk...
  12. ncbi request reprint Acute and sub-acute effects of 2-butenoic acid-3-(diethoxy phosphinothioyl) methyl ester (RPR-II) on testis of albino rat
    I A Khan
    Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 007, India
    Indian J Exp Biol 40:162-8. 2002
    ..The present study suggests that RPR-II may cause testicular toxicity in rats affecting the normal functioning of testis and it also gave some new information in withdrawal studies...
  13. doi request reprint Determination of genetic damage and urinary metabolites in fuel filling station attendants
    P V Rekhadevi
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 607, Andhra Pradesh, India
    Environ Mol Mutagen 52:310-8. 2011
    ..This study suggests the need for regular monitoring of FFSA for possible exposure to BTX as a precautionary and preventive step to minimize exposure and reduce the associated health risks...
  14. ncbi request reprint Assessment of genotoxic effects of chloropyriphos and acephate by the comet assay in mice leucocytes
    M F Rahman
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad, Andhra Pradesh 500007, India
    Mutat Res 516:139-47. 2002
    ..From the study it can be concluded that the comet assay is a sensitive assay for the detection of genotoxicity caused by pesticides...
  15. ncbi request reprint Effects of Vepacide (Azadirachta indica) on aspartate and alanine aminotransferase profiles in a subchronic study with rats
    M F Rahman
    Biology Division, Indian Institute of Chemical Technology, Hyderabad
    Hum Exp Toxicol 20:243-9. 2001
    ..This study has indicated that these enzymes could be useful as biomarkers for the insult of any toxicant. Besides, they can also help in predictive toxicology...
  16. ncbi request reprint Genotoxic effect of monocrotophos to sentinel species using comet assay
    B Saleha Banu
    Indian Institute of Chemical Technology, Toxicology Unit, Biology and Biotechnology Division, A.P. 500 007, Hyderabad, India
    Food Chem Toxicol 39:361-6. 2001
    ..The study reveals that the comet assay is a sensitive and rapid method to detect genotoxicity of monocrotophos and other environmental pollutants in sentinel species...
  17. ncbi request reprint Genotoxic evaluation of workers employed in pesticide production
    N Sailaja
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500007, Andhra Pradesh, India
    Mutat Res 609:74-80. 2006
    ..05). Our findings indicate that occupational exposure to pesticides could cause genome damage in somatic cells...
  18. pmc Monitoring of oxidative stress in nurses occupationally exposed to antineoplastic drugs
    M Mahboob
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Tarnaka, Habsiguda, Hyderabad 500 607, India
    Toxicol Int 19:20-4. 2012
    ..Our study suggests that the nurses occupationally exposed to ANDs were susceptible to the oxidative stress and emphasizes the need for a harmonized safe handling approach that assures minimal risk to the working nurses...
  19. doi request reprint In vitro mutagenicity assessment of aluminium oxide nanomaterials using the Salmonella/microsome assay
    A Balasubramanyam
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad, Andhra Pradesh, India
    Toxicol In Vitro 24:1871-6. 2010
    ..Our findings suggest that Al(2)O(3) NMs were devoid of any size and concentration dependent mutagenicity compared to the Al(2)O(3)-bulk and control...
  20. ncbi request reprint Sub-chronic effect of neem based pesticide (Vepacide) on acetylcholinesterase and ATPases in rat
    M F Rahman
    Toxicology Unit, Indian Institute of Chemical Technology, Hyderabad, India
    J Environ Sci Health B 34:873-84. 1999
    ..These results indicated that the ATPases were potently inhibited by Vepacide and seemed to be its precise target among the enzyme studied. This can be used as biochemical marker of exposure to this neem derived product...
  21. doi request reprint Comparative study of genotoxicity and tissue distribution of nano and micron sized iron oxide in rats after acute oral treatment
    Shailendra Pratap Singh
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 007, Andhra Pradesh, India
    Toxicol Appl Pharmacol 266:56-66. 2013
    ..However, the accumulated Fe did not cause significant genotoxicity. This study provides additional knowledge about the toxicology of Fe(2)O(3) NMs...
  22. doi request reprint Biomarkers of oxidative stress in rat for assessing toxicological effects of heavy metal pollution in river water
    Utkarsh A Reddy
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad, Telangana, 500007, India
    Environ Sci Pollut Res Int 22:13453-63. 2015
    ..In conclusion, the findings of this study clearly indicate the oxidative stress condition in rat organs due to repeated oral treatment of polluted Musi river water. ..
  23. ncbi request reprint Biochemical effects of vepacide (from Azadirachta indica) on Wistar rats during subchronic exposure
    M F Rahman
    Biochemical Toxicology, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 007, India
    Ecotoxicol Environ Saf 59:332-9. 2004
    ..The decrease in liver AcP may be due to the necrosis of cellular tissues. The changes observed in these enzyme activities could be useful as biomarkers of exposure to Vepacide...
  24. ncbi request reprint In vitro acetylcholinesterase inhibition by novel OP compounds in various tissues of the fish Channa punctatus
    M F Rahman
    Biochemical Toxicology, Biology Division, Indian Institute of Chemical Technology, Hyderabad
    Bull Environ Contam Toxicol 72:38-44. 2004
  25. ncbi request reprint Assessment of genotoxicity in female agricultural workers exposed to pesticides
    Rekhadevi Perumalla Venkata
    a Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad, Telangana, India
    Biomarkers . 2016
    ..This study was designed to determine the genotoxic effect of exposure to a mixture of pesticides in 106 female agricultural workers employed in cotton fields from India...
  26. doi request reprint Genotoxic effects of chromium oxide nanoparticles and microparticles in Wistar rats after 28 days of repeated oral exposure
    Shailendra Pratap Singh
    Toxicology Unit, Biology Division, CSIR Indian Institute of Chemical Technology, Hyderabad, Telangana, 500 007, India
    Environ Sci Pollut Res Int 23:3914-24. 2016
    ..These findings provide initial data of the probable genotoxicity and biodistribution of NPs and MPs of Cr2O3 generated through repeated oral treatment...
  27. ncbi request reprint Serum lipid peroxidation and antioxidant enzyme levels in male and female diabetic patients
    M Mahboob
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Tarnaka, Habshiguda, Hyderabad 500007, India
    Singapore Med J 46:322-4. 2005
    ..This study aims to evaluate blood serum lipid peroxidation product (malondialdehyde), an antioxidant, in non-insulin dependent male and female type 2 diabetic patients...
  28. ncbi request reprint LDH profiles of male and female rats treated with Vepacide
    M F Rahman
    Biochemical Toxicology, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 007, India
    Phytother Res 16:122-6. 2002
    ..Necrosis of the liver and kidney tissues was observed but in the lung tissue an increase in the LDH enzyme was seen. Therefore, it was concluded that the increase in LDH could be indicative of a stress adaptive response to the toxicant...
  29. ncbi request reprint Detection of DNA damage in mouse peripheral blood leukocytes by the comet assay after oral administration of monocrotophos
    M Mahboob
    Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500 007, India
    Drug Chem Toxicol 25:65-74. 2002
    ..The mean tail length showed a dose-related increase and time dependent decrease. The study reveals that comet assay is a sensitive and rapid method to detect genotoxicity of monocrotophos...
  30. ncbi request reprint Effect of diplodiatoxin (Stenocarpella maydis) on some enzymatic profiles in male and female rats
    M F Rahman
    Department of Microbiology, University of Durban Westville, X 54001, Durban, 4000, South Africa
    Ecotoxicol Environ Saf 52:267-72. 2002
    ..These results suggest that diplodiatoxin is toxic and has potential to affect the normal functioning of individuals and can cause changes in vital tissues such as liver...
  31. ncbi request reprint Biochemical changes induced in liver and serum of diplodiatoxin (Stenocarpella maydis) treated male and female rats
    Shailaja K Rao
    Department of Microbiology, University of Durban Westville, Durban, South Africa
    Drug Chem Toxicol 26:231-43. 2003
    ..These enzyme profiles show increases in serum with parallel decrease in liver, indicating necrosis of liver. These results suggest that diplodiatoxin has potential to affect hepatic end-points...