Manoj B Mahimkar

Summary

Affiliation: Navi Mumbai
Country: India

Publications

  1. pmc Genomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome
    Srikant Ambatipudi
    Tata Memorial Centre, Advanced Centre for Treatment, Research and Education in Cancer, Cancer Research Institute, Navi Mumbai, India
    PLoS ONE 6:e17250. 2011
  2. doi request reprint Polymorphisms in GSTM1 and XPD genes predict clinical outcome in advanced oral cancer patients treated with postoperative radiotherapy
    Manoj B Mahimkar
    Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, India
    Mol Carcinog 51:E94-103. 2012
  3. doi request reprint Influence of genetic polymorphisms on frequency of micronucleated buccal epithelial cells in leukoplakia patients
    Manoj B Mahimkar
    Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer ACTREC, Tata Memorial Centre, Navi Mumbai 410210, India
    Oral Oncol 46:761-6. 2010
  4. pmc Downregulation of keratin 76 expression during oral carcinogenesis of human, hamster and mouse
    Srikant Ambatipudi
    Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, India
    PLoS ONE 8:e70688. 2013
  5. ncbi request reprint Susceptibility to oral cancer by genetic polymorphisms at CYP1A1, GSTM1 and GSTT1 loci among Indians: tobacco exposure as a risk modulator
    Devasena Anantharaman
    Cancer Research Institute, Advanced Center for Treatment, Research and Education in Cancer, Tata Memorial Center, Kharghar, Navi Mumbai 410 208, India
    Carcinogenesis 28:1455-62. 2007
  6. doi request reprint Polymorphisms in tobacco metabolism and DNA repair genes modulate oral precancer and cancer risk
    Devasena Anantharaman
    Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai 410210, India
    Oral Oncol 47:866-72. 2011
  7. pmc Genome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancers
    Srikant Ambatipudi
    Cancer Research Institute CRI, Advanced Centre for Treatment, Research and Education in Cancer ACTREC, Tata Memorial Centre TMC, Navi Mumbai, India
    Genes Chromosomes Cancer 51:161-73. 2012

Collaborators

  • Niko Beerenwinkel
  • Devasena Anantharaman
  • Fiona M Watt
  • Srikant Ambatipudi
  • Rajiv S Desai
  • Shubhada Kane
  • Asawari Patil
  • Manishkumar Pandey
  • Alejandro A Schäffer
  • Moritz Gerstung
  • Emma Heath
  • Gaurav Kumar
  • Girish B Maru
  • Priyanka G Bhosale
  • Tanuja Samant
  • Ravindra Gowda
  • Prathamesh Pai
  • Anita M Borges

Detail Information

Publications7

  1. pmc Genomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome
    Srikant Ambatipudi
    Tata Memorial Centre, Advanced Centre for Treatment, Research and Education in Cancer, Cancer Research Institute, Navi Mumbai, India
    PLoS ONE 6:e17250. 2011
    ..This study identifies a tractable number of genomic alterations with few underlying genes that may potentially be utilized as biological markers for prognosis and treatment decisions in oral cancers...
  2. doi request reprint Polymorphisms in GSTM1 and XPD genes predict clinical outcome in advanced oral cancer patients treated with postoperative radiotherapy
    Manoj B Mahimkar
    Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, India
    Mol Carcinog 51:E94-103. 2012
    ..GSTM1 and XPD variant alleles, independently as well as in combination may serve as important predictors of clinical outcome in radiotherapy-treated OSCC patients...
  3. doi request reprint Influence of genetic polymorphisms on frequency of micronucleated buccal epithelial cells in leukoplakia patients
    Manoj B Mahimkar
    Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer ACTREC, Tata Memorial Centre, Navi Mumbai 410210, India
    Oral Oncol 46:761-6. 2010
    ..03 respectively). In conclusion, the extent of chromosomal damage in target tissues is higher in patients with OL. MNC frequency in combination with genetic polymorphisms in DNA repair genes may serve as better predicator of risk...
  4. pmc Downregulation of keratin 76 expression during oral carcinogenesis of human, hamster and mouse
    Srikant Ambatipudi
    Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, India
    PLoS ONE 8:e70688. 2013
    ..Previous study from our lab revealed deregulation of many genes related to structural molecular integrity including KRT76. Here we evaluate the role of KRT76 downregulation in oral precancer and cancer development...
  5. ncbi request reprint Susceptibility to oral cancer by genetic polymorphisms at CYP1A1, GSTM1 and GSTT1 loci among Indians: tobacco exposure as a risk modulator
    Devasena Anantharaman
    Cancer Research Institute, Advanced Center for Treatment, Research and Education in Cancer, Tata Memorial Center, Kharghar, Navi Mumbai 410 208, India
    Carcinogenesis 28:1455-62. 2007
    ..These results support the finding that GSTM1 null genotype is a risk factor to OSCC among Indian tobacco habits; GSTT1 null genotype, however, emerged as a protective factor...
  6. doi request reprint Polymorphisms in tobacco metabolism and DNA repair genes modulate oral precancer and cancer risk
    Devasena Anantharaman
    Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai 410210, India
    Oral Oncol 47:866-72. 2011
    ..We report that genetic variants associated with premalignant and malignant conditions of the oral cavity differ. The associations appeared to be consistent among smokeless tobacco users, a characteristic risk factor in these parts...
  7. pmc Genome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancers
    Srikant Ambatipudi
    Cancer Research Institute CRI, Advanced Centre for Treatment, Research and Education in Cancer ACTREC, Tata Memorial Centre TMC, Navi Mumbai, India
    Genes Chromosomes Cancer 51:161-73. 2012
    ..2011 Wiley Periodicals, Inc...