Madhuri R Thakar

Summary

Affiliation: National AIDS Research Institute
Country: India

Publications

  1. ncbi request reprint CD4+ T cell count as a tool to monitor HIV progression & anti-retroviral therapy
    Kovit Pattanapanyasat
    Center of Excellence for Flow Cytometry, Office for Research and Development, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Indian J Med Res 121:539-49. 2005
  2. pmc Comparison of capillary based microflurometric assay for CD4+ T cell count estimation with dual platform Flow cytometry
    Madhuri R Thakar
    National AIDS Research Institute, Bhosari, Pune 411026, India
    AIDS Res Ther 3:26. 2006
  3. pmc Utility of the point of care CD4 analyzer, PIMA, to enumerate CD4 counts in the field settings in India
    Madhuri Thakar
    Department of Immunology, National AIDS Research Institute, G 73, MIDC, Bhosari, Pune, 411 026, India
    AIDS Res Ther 9:26. 2012
  4. pmc Variations in autologous neutralization and CD4 dependence of b12 resistant HIV-1 clade C env clones obtained at different time points from antiretroviral naïve Indian patients with recent infection
    Rajesh Ringe
    Department of Molecular Virology, National AIDS Research Institute, Indian Council of Medical Research, G 73 MIDC, Bhosari, Pune, India
    Retrovirology 7:76. 2010
  5. pmc Establishment of reference CD4+ T cell values for adult Indian population
    Madhuri R Thakar
    Department of Immunology, National AIDS Research Institute, G 73, MIDC, Bhosari, Pune, 411026, India
    AIDS Res Ther 8:35. 2011
  6. ncbi request reprint Cytolytic T lymphocytes (CTLs) from HIV-1 subtype C-infected Indian patients recognize CTL epitopes from a conserved immunodominant region of HIV-1 Gag and Nef
    Madhuri R Thakar
    National AIDS Research Institute, Bhosari, Pune, India
    J Infect Dis 192:749-59. 2005
  7. ncbi request reprint Extensive cross-reactive neutralizing antibody response in Indian patients with limited genetic diversity of HIV-1
    Samir K Lakhashe
    National AIDS Research Institute, G 73, MIDC, Bhosari, Pune 411 026, India
    Virology 359:295-301. 2007
  8. ncbi request reprint Consistent subtype-specific anti-HIV type 1 T lymphocyte responses in Indian subjects recently infected with HIV type 1
    Madhuri R Thakar
    National AIDS Research Institute, Pune 411026, India
    AIDS Res Hum Retroviruses 18:1389-93. 2002
  9. ncbi request reprint Dysregulation of proinflammatory and regulatory cytokines in HIV infected persons with active tuberculosis
    Abhijit M Bal
    National AIDS Research Institute, G 73, MIDC, Bhosari, Pune 411 026, India
    Cytokine 30:275-81. 2005
  10. pmc Quantitation of HLA proteins incorporated by human immunodeficiency virus type 1 and assessment of neutralizing activity of anti-HLA antibodies
    Samir K Lakhashe
    National AIDS Research Institute, G 73, MIDC, Bhosari, Pune, India
    J Virol 82:428-34. 2008

Collaborators

Detail Information

Publications12

  1. ncbi request reprint CD4+ T cell count as a tool to monitor HIV progression & anti-retroviral therapy
    Kovit Pattanapanyasat
    Center of Excellence for Flow Cytometry, Office for Research and Development, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Indian J Med Res 121:539-49. 2005
    ..Importance of maintaining both internal and external quality control systems in every laboratory performing CD4 count estimation are discussed...
  2. pmc Comparison of capillary based microflurometric assay for CD4+ T cell count estimation with dual platform Flow cytometry
    Madhuri R Thakar
    National AIDS Research Institute, Bhosari, Pune 411026, India
    AIDS Res Ther 3:26. 2006
    ..The system is compact and generates minimum amount of waste. Hence the EasyCD4 System could be applied for estimation of CD4+ T cell counts in resource poor settings...
  3. pmc Utility of the point of care CD4 analyzer, PIMA, to enumerate CD4 counts in the field settings in India
    Madhuri Thakar
    Department of Immunology, National AIDS Research Institute, G 73, MIDC, Bhosari, Pune, 411 026, India
    AIDS Res Ther 9:26. 2012
    ..This study is aimed at determining the utility of a Point of Care PIMA CD4 analyzer (Alere, Germany) in the field settings in India...
  4. pmc Variations in autologous neutralization and CD4 dependence of b12 resistant HIV-1 clade C env clones obtained at different time points from antiretroviral naïve Indian patients with recent infection
    Rajesh Ringe
    Department of Molecular Virology, National AIDS Research Institute, Indian Council of Medical Research, G 73 MIDC, Bhosari, Pune, India
    Retrovirology 7:76. 2010
    ....
  5. pmc Establishment of reference CD4+ T cell values for adult Indian population
    Madhuri R Thakar
    Department of Immunology, National AIDS Research Institute, G 73, MIDC, Bhosari, Pune, 411026, India
    AIDS Res Ther 8:35. 2011
    ..The nationwide reference range of CD4+ T lymphocytes was not available in India. This study was conducted to determine reference values of absolute CD4+ T cell counts and percentages for adult Indian population...
  6. ncbi request reprint Cytolytic T lymphocytes (CTLs) from HIV-1 subtype C-infected Indian patients recognize CTL epitopes from a conserved immunodominant region of HIV-1 Gag and Nef
    Madhuri R Thakar
    National AIDS Research Institute, Bhosari, Pune, India
    J Infect Dis 192:749-59. 2005
    ..Three Gag and 4 Nef epitopes were novel. The identification of conserved epitopes will be important in the planning of an HIV-1 vaccine strategy for subtype C-affected regions...
  7. ncbi request reprint Extensive cross-reactive neutralizing antibody response in Indian patients with limited genetic diversity of HIV-1
    Samir K Lakhashe
    National AIDS Research Institute, G 73, MIDC, Bhosari, Pune 411 026, India
    Virology 359:295-301. 2007
    ..The neutralizing antibody response showed extensive cross-neutralization, suggesting presence of shared neutralization determinants among circulating HIV-1 subtype C viruses in India...
  8. ncbi request reprint Consistent subtype-specific anti-HIV type 1 T lymphocyte responses in Indian subjects recently infected with HIV type 1
    Madhuri R Thakar
    National AIDS Research Institute, Pune 411026, India
    AIDS Res Hum Retroviruses 18:1389-93. 2002
    ..336, p = 0.054 for subtype C and r = -0.234, p = 0.13 for subtype B). The data suggest that the patients exhibiting consistent subtype-specific responses to HIV-1 Gag might have better control of viral replication in early HIV infection...
  9. ncbi request reprint Dysregulation of proinflammatory and regulatory cytokines in HIV infected persons with active tuberculosis
    Abhijit M Bal
    National AIDS Research Institute, G 73, MIDC, Bhosari, Pune 411 026, India
    Cytokine 30:275-81. 2005
    ..The mitogen induced cytokine secretion was generally lower in HIV-TB coinfected patients indicating profound perturbation of both Th1 and Th2 responses...
  10. pmc Quantitation of HLA proteins incorporated by human immunodeficiency virus type 1 and assessment of neutralizing activity of anti-HLA antibodies
    Samir K Lakhashe
    National AIDS Research Institute, G 73, MIDC, Bhosari, Pune, India
    J Virol 82:428-34. 2008
    ..This study shows that HIV-1 primary isolates cultured in PBMCs contain significant amounts of HLA proteins. However, the binding of antibodies to those HLA proteins does not mediate a reduction in viral infectivity...
  11. pmc T-cell Epitopes Identified by BALB/c Mice Immunized with Vaccinia Expressing HIV-1 Gag lie within immunodominant Regions Recognized by HIV-infected Indian Patients
    Ashwini V Shete
    Department of Immunology and Molecular Virology, Pune, India
    J Glob Infect Dis 3:246-53. 2011
    ....
  12. ncbi request reprint Limited evolution in the HIV type 1 pol region among acute seroconverters in Pune, India
    Susan H Eshleman
    The Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
    AIDS Res Hum Retroviruses 21:93-7. 2005
    ..Amino acid substitutions were rare, and varied from subject to subject. In this cohort, drug resistance was not observed and evolution in the pol region was very limited during the first 2 years of infection...