- Bactericidal effects of fatty acids and monoglycerides on Helicobacter pyloriGudmundur Bergsson
Institute of Biology, University of Iceland, Grensasvegur 12, 108, Reykjavik, Iceland
Int J Antimicrob Agents 20:258-62. 2002..pylori, monocaprin and monolaurin being the most active. The high activity of monoglycerides against H. pylori suggests that they may be useful as active ingredients in pharmaceutical formulations...
- Isolation and identification of antimicrobial components from the epidermal mucus of Atlantic cod (Gadus morhua)Gudmundur Bergsson
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
FEBS J 272:4960-9. 2005..The broad spectra of antimicrobial activities in the cod mucus and the characterization of four antimicrobial polypeptides suggest that mucus compounds contribute to the innate host defence of cod...
- LL-37 complexation with glycosaminoglycans in cystic fibrosis lungs inhibits antimicrobial activity, which can be restored by hypertonic salineGudmundur Bergsson
Department of Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland
J Immunol 183:543-51. 2009....
- The effect of Aspergillus fumigatus infection on vitamin D receptor expression in cystic fibrosisCatherine A Coughlan
Respiratory Research Division, Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland
Am J Respir Crit Care Med 186:999-1007. 2012..Although allergic bronchopulmonary aspergillosis (ABPA) leads to deterioration of pulmonary function, the effect of A. fumigatus colonization in the absence of ABPA remains unclear...
- Antimicrobial components of the neonatal gut affected upon colonizationYlva Kai-Larsen
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 171 77 Stockholm, Sweden
Pediatr Res 61:530-6. 2007..Our findings reveal that meconium and feces contain AMP, acting in the defense of the neonatal gut, and may be implicated in the control of the initial colonization...
- Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinasesNicolas Guyot
Department of Medicine, Pulmonary Research Division, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland
Biol Chem 391:705-16. 2010..In conclusion, this study provides evidence that elafin is susceptible to proteolytic cleavage at alternative sites by P. aeruginosa metalloproteinases, which can affect different biological functions of elafin...
- Stable concentrated emulsions of the 1-monoglyceride of capric acid (monocaprin) with microbicidal activities against the food-borne bacteria Campylobacter jejuni, Salmonella spp., and Escherichia coliHalldor Thormar
Institute of Biology, University of Iceland, Askja, Sturlugata 7, 101 Reykjavik, Iceland
Appl Environ Microbiol 72:522-6. 2006..These results are discussed in view of the possible utilization of monocaprin emulsions in controlling the spread of food-borne bacteria from poultry to humans...