Stephan Huveneers

Summary

Publications

  1. pmc Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling
    Stephan Huveneers
    Hubrecht Institute for Developmental Biology and Stem Cell Research, University Medical Centre Utrecht, 3584 CT, Utrecht, Netherlands
    J Cell Biol 196:641-52. 2012
  2. doi The interaction of SRC kinase with beta3 integrin tails: a potential therapeutic target in thrombosis and cancer
    Stephan Huveneers
    Dynamics of Cell Adhesion, Hubrecht Institute and University Medical Centre Utrecht, The Netherlands
    ScientificWorldJournal 10:1100-5. 2010
  3. doi Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control
    Willem Jan Pannekoek
    Molecular Cancer Research, Centre of Biomedical Genetics and Cancer Genomics Centre, University Medical Center Utrecht, Utrecht, The Netherlands
    Cell Signal 23:2056-64. 2011
  4. pmc VASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin module
    Joppe Oldenburg
    Dept Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Stratenum 3 231, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands
    Sci Rep 5:17225. 2015

Collaborators

Detail Information

Publications4

  1. pmc Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling
    Stephan Huveneers
    Hubrecht Institute for Developmental Biology and Stem Cell Research, University Medical Centre Utrecht, 3584 CT, Utrecht, Netherlands
    J Cell Biol 196:641-52. 2012
    ..These findings implicate Vinculin-dependent cadherin mechanosensing in endothelial processes such as leukocyte extravasation and angiogenesis...
  2. doi The interaction of SRC kinase with beta3 integrin tails: a potential therapeutic target in thrombosis and cancer
    Stephan Huveneers
    Dynamics of Cell Adhesion, Hubrecht Institute and University Medical Centre Utrecht, The Netherlands
    ScientificWorldJournal 10:1100-5. 2010
    ....
  3. doi Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control
    Willem Jan Pannekoek
    Molecular Cancer Research, Centre of Biomedical Genetics and Cancer Genomics Centre, University Medical Center Utrecht, Utrecht, The Netherlands
    Cell Signal 23:2056-64. 2011
    ..We conclude that PDZ-GEF activates Rap1 under resting conditions to stabilize cell-cell junctions and maintain basal integrity. Activation of Rap1 by cAMP/Epac1 induces junctional actin to further tighten cell-cell contacts...
  4. pmc VASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin module
    Joppe Oldenburg
    Dept Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Stratenum 3 231, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands
    Sci Rep 5:17225. 2015
    ..We conclude that there are multiple force sensitive modules present at the FAJ that are activated at distinct locations along the cadherin-F-actin axis and regulate specific aspects of junction dynamics. ..