- [Nintedanib (BIBF 1120) in the treatment of solid cancers: an overview of biological and clinical aspects]Szilvia Torok
Tumorbiológiai Osztály, Országos Korányi Tbc és Pulmonológiai Intézet, Budapest, Hungary
Magy Onkol 56:199-208. 2012..Nintedanib might also be combined with paclitaxel, carboplatin, pemetrexed and docetaxel. There are several ongoing clinical trials testing the efficacy of BIBF 1120...
- [Possibilities for inhibiting tumor-induced angiogenesis: results with multi-target tyrosine kinase inhibitors]Szilvia Torok
Országos Korányi Tbc és Pulmonológiai Intézet, Tumorbiológiai Osztály, Budapest, Hungary
Magy Onkol 56:3-15. 2012..On the other hand, the optimal combination and dosage of these drugs, selection of the apropriate biomarker and better understanding of the conflicting role of PDGFR and FGFR signaling in angiogenesis remain future challenges...
- Apelin promotes lymphangiogenesis and lymph node metastasisJudit Berta
Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria Department of Tumor Biology, National Koranyi Institute of Pulmonology, Budapest, Hungary
Oncotarget 5:4426-37. 2014..Our study does not only reveal apelin as a novel lymphangiogenic factor but might also open the door for the development of novel anticancer therapies targeting lymphangiogenesis. ..
- Lung cancer in never smokersSzilvia Torok
National Koranyi Institute of Pulmonology, Budapest, Hungary
Future Oncol 7:1195-211. 2011..Future studies on LCINS should try to tackle the issues of prevention, early diagnosis and the exploration of novel therapeutic targets to combat lung cancer disease...