Laszlo Czirjak

Summary

Country: Hungary

Publications

  1. ncbi request reprint Exposure to solvents in female patients with scleroderma
    L Czirjak
    Clinical Immunology Unit, Medical Faculty, University of Pecs, Hungary
    Clin Rheumatol 21:114-8. 2002
  2. ncbi request reprint Survival and causes of death in 366 Hungarian patients with systemic sclerosis
    L Czirjak
    University of Pecs, Medical School, Department of Immunology and Rheumatology, H 7621 Pecs, Hungary
    Ann Rheum Dis 67:59-63. 2008
  3. pmc International cohort study of 73 anti-Ku-positive patients: association of p70/p80 anti-Ku antibodies with joint/bone features and differentiation of disease populations by using principal-components analysis
    Katja Lakota
    Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia
    Arthritis Res Ther 14:R2. 2012
  4. doi request reprint Skin involvement in systemic sclerosis
    L Czirjak
    Department of Immunology and Rheumatology, University of Pecs, Pecs, Hungary
    Rheumatology (Oxford) 47:v44-5. 2008
  5. ncbi request reprint [Patient care management in autoimmune disorders--the structure of treatment]
    Laszlo Czirjak
    Pécsi Egyetem, Általános Orvostudományi Kar, Immunológiai és Reumatológiai Klinika, Pecs
    Orv Hetil 148:78-80. 2007
  6. ncbi request reprint [Does the number of patients with autoimmune disorders and the frequency of autoimmune diseases increase?]
    Laszlo Czirjak
    Pécsi Egyetem, Általános Orvostudományi Kar, Immunológiai és Reumatológiai Klinika, Pecs
    Orv Hetil 148:17-20. 2007
  7. pmc The EUSTAR model for teaching and implementing the modified Rodnan skin score in systemic sclerosis
    Laszlo Czirjak
    Department of Immunology and Rheumatology, University of Pecs, H 7621 Pecs, Irgalmasok u 1, Hungary
    Ann Rheum Dis 66:966-9. 2007
  8. ncbi request reprint Practical approach to the therapy of systemic sclerosis
    L Czirjak
    Head of the Department of Immunology and Rheumatology, Hungarian Brothers of St John of God and University of Pécs, Faculty of Medicine, Irgalmasok utcája 1, Pf 99, 7621 Pécs, Ungarn
    Z Rheumatol 63:451-6. 2004
  9. ncbi request reprint Survey of Raynaud's phenomenon and systemic sclerosis based on a representative study of 10,000 south-Transdanubian Hungarian inhabitants
    L Czirjak
    Department of Immunology and Rheumatology, Medical School, Hungarian Brothers of St John of God and University of Pécs, Hungary
    Clin Exp Rheumatol 23:801-8. 2005
  10. ncbi request reprint A possible new bridge between innate and adaptive immunity: Are the anti-mitochondrial citrate synthase autoantibodies components of the natural antibody network?
    Tamas Czompoly
    Department of Immunology and Biotechnology, Faculty of Medicine, University of Pecs, Szigeti ut 12, Pécs H 7643, Hungary
    Mol Immunol 43:1761-8. 2006

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Exposure to solvents in female patients with scleroderma
    L Czirjak
    Clinical Immunology Unit, Medical Faculty, University of Pecs, Hungary
    Clin Rheumatol 21:114-8. 2002
    ..Furthermore, exposure to solvents does not seem to be a provoking factor among females for the other connective tissue diseases...
  2. ncbi request reprint Survival and causes of death in 366 Hungarian patients with systemic sclerosis
    L Czirjak
    University of Pecs, Medical School, Department of Immunology and Rheumatology, H 7621 Pecs, Hungary
    Ann Rheum Dis 67:59-63. 2008
    ..Survival analysis of a series of 366 consecutive patients with systemic sclerosis (SSc)...
  3. pmc International cohort study of 73 anti-Ku-positive patients: association of p70/p80 anti-Ku antibodies with joint/bone features and differentiation of disease populations by using principal-components analysis
    Katja Lakota
    Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia
    Arthritis Res Ther 14:R2. 2012
    ....
  4. doi request reprint Skin involvement in systemic sclerosis
    L Czirjak
    Department of Immunology and Rheumatology, University of Pecs, Pecs, Hungary
    Rheumatology (Oxford) 47:v44-5. 2008
    ..The measurement of late-stage, irreversible skin damage/atrophy should be resolved in the future through the development and validation of new instruments...
  5. ncbi request reprint [Patient care management in autoimmune disorders--the structure of treatment]
    Laszlo Czirjak
    Pécsi Egyetem, Általános Orvostudományi Kar, Immunológiai és Reumatológiai Klinika, Pecs
    Orv Hetil 148:78-80. 2007
  6. ncbi request reprint [Does the number of patients with autoimmune disorders and the frequency of autoimmune diseases increase?]
    Laszlo Czirjak
    Pécsi Egyetem, Általános Orvostudományi Kar, Immunológiai és Reumatológiai Klinika, Pecs
    Orv Hetil 148:17-20. 2007
    ..Assigned to the increasing number of variable chronic autoimmune disorders, and the increasing number of disabled patients with such diseases increasing medical and social attention has to be focused on...
  7. pmc The EUSTAR model for teaching and implementing the modified Rodnan skin score in systemic sclerosis
    Laszlo Czirjak
    Department of Immunology and Rheumatology, University of Pecs, H 7621 Pecs, Irgalmasok u 1, Hungary
    Ann Rheum Dis 66:966-9. 2007
    ..To evaluate the ability to teach scleroderma experts and young rheumatologists to perform the modified Rodnan skin score test...
  8. ncbi request reprint Practical approach to the therapy of systemic sclerosis
    L Czirjak
    Head of the Department of Immunology and Rheumatology, Hungarian Brothers of St John of God and University of Pécs, Faculty of Medicine, Irgalmasok utcája 1, Pf 99, 7621 Pécs, Ungarn
    Z Rheumatol 63:451-6. 2004
    ..Education of patients is also compelling...
  9. ncbi request reprint Survey of Raynaud's phenomenon and systemic sclerosis based on a representative study of 10,000 south-Transdanubian Hungarian inhabitants
    L Czirjak
    Department of Immunology and Rheumatology, Medical School, Hungarian Brothers of St John of God and University of Pécs, Hungary
    Clin Exp Rheumatol 23:801-8. 2005
    ..To assess the prevalence of Raynaud's phenomenon (RP) and of RP associated systemic sclerosis (SSc) in a large regional representative study...
  10. ncbi request reprint A possible new bridge between innate and adaptive immunity: Are the anti-mitochondrial citrate synthase autoantibodies components of the natural antibody network?
    Tamas Czompoly
    Department of Immunology and Biotechnology, Faculty of Medicine, University of Pecs, Szigeti ut 12, Pécs H 7643, Hungary
    Mol Immunol 43:1761-8. 2006
    ..Thus, at the level of recognized epitopes there is a possible new link between the innate like component and the adaptive-autoimmune arm of the humoral immune system...
  11. doi request reprint Naturally occurring and disease-associated auto-antibodies against topoisomerase I: a fine epitope mapping study in systemic sclerosis and systemic lupus erythematosus
    Diana Simon
    Department of Immunology and Rheumatology, University of Pecs, Pecs, Hungary
    Int Immunol 21:415-22. 2009
    ..According to our results, the newly identified fragments F1 and F8 could represent characteristic epitopes for dcSSc and SLE, respectively...
  12. ncbi request reprint Prevalence of rheumatoid arthritis in the South-Transdanubian region of Hungary based on a representative survey of 10,000 inhabitants
    Csaba G Kiss
    Department of Immunology and Rheumatology, Medical School, Hungarian Brothers of St John of God and University of Pécs, Hungary
    J Rheumatol 32:1688-90. 2005
    ..To assess the prevalence of rheumatoid arthritis (RA) in a representative study of the South Transdanubian region of Hungary...
  13. ncbi request reprint Simultaneous presence of neutrophil alveolitis and Ki-67 positivity of alveolar macrophages in dermato-/polymyositis and systemic sclerosis
    Gábor Kumánovics
    Department of Immunology and Rheumatology, Faculty of Medicine, Hungarian Brothers of St John of God and University of Pécs, 7621 Pécs, Hungary
    Rheumatol Int 23:6-10. 2003
    ....
  14. doi request reprint Construct validity evaluation of the European Scleroderma Study Group activity index, and investigation of possible new disease activity markers in systemic sclerosis
    Tunde Minier
    Department of Immunology and Rheumatology, Clinic Center, University of Pecs, Akác u 1, H 7632 Pécs, Hungary
    Rheumatology (Oxford) 49:1133-45. 2010
    ..To evaluate the construct validity of the European Scleroderma Study Group (EScSG) activity index and to propose modifications if necessary...
  15. ncbi request reprint Reduced non-switched memory B cell subsets cause imbalance in B cell repertoire in systemic sclerosis
    Diana Simon
    Department of Immunology and Biotechnology, University of Pecs, Clinical Center, Pecs, Hungary
    Clin Exp Rheumatol 34:30-36. 2016
    ..However, memory B cell subsets in SSc have not been thoroughly investigated. This study sought to identify phenotypic abnormalities and activation markers in peripheral blood memory B cells in SSc subtypes...
  16. doi request reprint The impact of cardiopulmonary manifestations on the mortality of SSc: a systematic review and meta-analysis of observational studies
    Andras Komocsi
    Department of Interventional Cardiology, Heart Institute, University of Pecs, Hungary
    Rheumatology (Oxford) 51:1027-36. 2012
    ..We aimed to perform a systematic review and meta-analysis to define more precise effect estimates of different cardiopulmonary manifestations and to verify trends in the mortality of SSc...
  17. doi request reprint Interleukin-23 receptor gene variants in Hungarian systemic lupus erythematosus patients
    Eniko Safrany
    Department of Medical Genetics, University of Pecs, Szigeti 12, 7624 Pecs, Hungary
    Inflamm Res 59:159-64. 2010
    ....
  18. doi request reprint Protein tyrosine phosphatase gene C1858T allele confers risk for rheumatoid arthritis in Hungarian subjects
    Bernadett Farago
    Department of Medical Genetics and Child Development, University of Pecs, Szigeti ut 12, 7624, Pecs, Hungary
    Rheumatol Int 29:793-6. 2009
    ....
  19. doi request reprint Anti-topoisomerase I autoantibodies in systemic sclerosis
    Tamas Czompoly
    Department of Immunology and Biotechnology, University of Pecs, Pecs, Hungary
    Autoimmun Rev 8:692-6. 2009
    ..In this review we summarize accumulated evidence about anti-topo I autoantibodies in SSc, including results of epitope mapping studies and investigations on the possible pathogenic role of these antibodies...
  20. ncbi request reprint [Role of physiotherapy in the rehabilitation of patients with idiopathic inflammatory myopathies]
    Cecília Varjú
    Magyarországi Irgalmasrend és a Pécsi Tudományegyetem Immunológiai és Reumatológiai Klinika, Pecs
    Orv Hetil 145:25-30. 2004
    ..The authors discuss in detail the special rehabilitation problems of myositis patients depending on the activity and subtype of the disease and the possible solutions...
  21. ncbi request reprint Cross-cultural adaptation of the disabilities of the arm, shoulder, and hand (DASH) questionnaire into Hungarian and investigation of its validity in patients with systemic sclerosis
    C Varjú
    Department of Immunology and Rheumatology, Faculty of Medicine, University of Pecs, Pecs, Hungary
    Clin Exp Rheumatol 26:776-83. 2008
    ..To adapt and validate the Hungarian version of the DASH and the shorter QuickDASH Outcome Measures and to establish their validity in patients with systemic sclerosis (SSc)...
  22. doi request reprint Overlap of coronary disease and pulmonary arterial hypertension in systemic sclerosis
    A Komocsi
    University of Pecs, Heart Institute, H 7624 Pecs, Ifjusag u 13, Hungary
    Ann Rheum Dis 69:202-5. 2010
    ..The aim of the present work was to investigate of the extent of overlap between CAD and PAH in patients with SSc...
  23. pmc Twenty-two points to consider for clinical trials in systemic sclerosis, based on EULAR standards
    Dinesh Khanna
    Division of Rheumatology, University of Michigan Scleroderma Program, Ann Arbor, MI, Division of Rheumatology, University of California at Los Angeles, Los Angeles, CA, USA, Department of Rheumatology A, Paris Descartes University, Cochin Institut, Inserm U1016, Cochin Hospital, Paris, France, Department of Medicine, Crozer Chester Medical Center, Upland, PA, USA, Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, Genoa, Italy, Department of Immunology and Rheumatology, University of Pecs, Pecs, Hungary, Centre for Rheumatology, Royal Free Hospital, London, UK, Department of Rheumatology, University Hospital Zurich, Zurich, Deparment of Rheumatology, Basel University, Basel, Switzerland, Department of Biomedicine, Division of Rheumatology, Azienda Ospedaliero Universitaria Careggi, Department of Medicine, Denothe Centre, University of Florence, Florence, Italy, Department of Rheumatology and Clinical Immunology, Justus Liebrig University Giessen, Kerckhoff Clinic, Department of Hematology
    Rheumatology (Oxford) 54:144-51. 2015
    ..Consensus standards for more uniform trial design and selection of outcome measures are needed. The objective of this study was to develop evidence-based points to consider (PTCs) for future clinical trials in SSc...
  24. doi request reprint Five-year follow-up of left ventricular diastolic function in systemic sclerosis patients: determinants of mortality and disease progression
    Reka Faludi
    Faculty of Medicine, Heart Institute, University of Pecs, Pecs, Hungary Electronic address
    Semin Arthritis Rheum 44:220-7. 2014
    ..We aimed to assess the abnormalities of the diastolic function, analyze the characteristics of the disease progression, and investigate the prognostic value of diastolic dysfunction in SSc patients...
  25. doi request reprint Cost-of-illness of patients with systemic sclerosis in a tertiary care centre
    Tunde Minier
    Department of Immunology and Rheumatology, Clinic Center, University of Pecs, Pecs, Akác u 1, H 7632, Hungary
    Rheumatology (Oxford) 49:1920-8. 2010
    ..The aim of our study was to assess the costs of SSc and to analyse cost drivers...
  26. ncbi request reprint Comprehensive investigation of novel serum markers of pulmonary fibrosis associated with systemic sclerosis and dermato/polymyositis
    G Kumanovics
    Department of Immunology and Rheumatology, Medical Faculty, University of Pecs, Pecs, Hungary
    Clin Exp Rheumatol 26:414-20. 2008
    ..To investigate the association between serum levels and clinical signs of lung fibrosis in patients with systemic sclerosis and inflammatory myopathies...
  27. ncbi request reprint Early morphologic and functional changes of atherosclerosis in systemic sclerosis-a systematic review and meta-analysis
    Zsófia Meiszterics
    Heart Institute, University of Pecs, Pecs
    Rheumatology (Oxford) 55:2119-2130. 2016
    ..Heterogeneous data are available regarding these in SSc. We aimed to perform a systematic review and meta-analysis to characterize the importance of atherosclerosis in SSc...
  28. doi request reprint Galectin-3 is an independent predictor of survival in systemic sclerosis
    Reka Faludi
    Heart Institute, Faculty of Medicine, University of Pecs, Pecs, Hungary Electronic address
    Int J Cardiol . 2016
    ..The aim of our study was to determine the associations between galectin-3 levels and patient characteristics, as well as to investigate the long term prognostic value of galectin-3 in a large cohort of SSc patients...
  29. doi request reprint Musculoskeletal involvement in systemic sclerosis
    Veronika Lóránd
    University of Pecs, Faculty of Medicine, Department of Rheumatology and Immunology, 7632 Pécs, Hungary
    Presse Med 43:e315-28. 2014
    ....
  30. doi request reprint Clinical usefulness of measuring red blood cell distribution width in patients with systemic sclerosis
    Nelli Farkas
    Institute of Bioanalysis, Institute of Family Medicine, Department of Rheumatology and Immunology, University of Pecs, Pécs and Third Department of Internal Medicine, Semmelweis University, Research Laboratory, Budapest, Hungary
    Rheumatology (Oxford) 53:1439-45. 2014
    ..SSc is characterized by generalized micro- and macroangiopathy. Our aim was to investigate RDW as a potential biomarker for the assessment of the severity of vascular involvement...
  31. ncbi request reprint Helicobacter pylori infection in connective tissue disorders is associated with high levels of antibodies to mycobacterial hsp65 but not to human hsp60
    Laszlo Kalabay
    3rd Department of Internal Medicine, Faculty of Medicine, Semmelweis University and Research Group of Metabolism, Genetics and Immunology, Hungarian Academy of Sciences, Budapest, Hungary
    Helicobacter 7:250-6. 2002
    ..pylori antibodies in autoimmune patients and healthy controls...
  32. doi request reprint Mechanism of coronary flow reserve reduction in systemic sclerosis: insight from intracoronary pressure wire studies
    Tünde Pintér
    Heart Institute, University of Pecs, H 7624 Pecs, Ifjusag 13, Hungary
    Rheumatology (Oxford) 50:781-8. 2011
    ..We aimed to investigate the mechanisms of coronary flow reserve (CFR) reduction in patients with SSc...
  33. ncbi request reprint Prevalence of functional haplotypes of the peptidylarginine deiminase citrullinating enzyme gene in patients with rheumatoid arthritis: no influence of the presence of anti-citrullinated peptide antibodies
    B Farago
    Department of Medical Genetics and Child Development, University of Pecs, Pecs, Hungary
    Clin Exp Rheumatol 25:523-8. 2007
    ..The peptidylarginine deiminase type 4 (PADI4) gene, which codes one of the PADI enzyme isotypes, has genetic variants that confer susceptibility to RA in Asian, but not in European populations...
  34. doi request reprint Preliminary analysis of the very early diagnosis of systemic sclerosis (VEDOSS) EUSTAR multicentre study: evidence for puffy fingers as a pivotal sign for suspicion of systemic sclerosis
    Tunde Minier
    Department of Rheumatology and Immunology, University of Pecs, Pecs, Hungary
    Ann Rheum Dis 73:2087-93. 2014
    ..Our aim was to assess the prevalence of each proposed diagnostic item in a large observational patient cohort with Raynaud's phenomenon (RP)...
  35. doi request reprint Investigation of sensory neurogenic components in a bleomycin-induced scleroderma model using transient receptor potential vanilloid 1 receptor- and calcitonin gene-related peptide-knockout mice
    Arpád Szabó
    University of Pecs, Pecs, Hungary
    Arthritis Rheum 58:292-301. 2008
    ..The aim of the present study was to examine the role of this modulatory role of TRPV1 receptor and that of calcitonin gene-related peptide (CGRP) in bleomycin-induced scleroderma, using transgenic mice...
  36. ncbi request reprint Functional variants of interleukin-23 receptor gene confer risk for rheumatoid arthritis but not for systemic sclerosis
    B Farago
    Department of Medical Genetics and Child Development, University of Pecs, H 7624 Pecs, Szigeti ut 12, Hungary
    Ann Rheum Dis 67:248-50. 2008
    ..Since the IL-23/IL-17 pathway is known to associate with other autoimmune diseases, including rheumatoid arthritis (RA) and systemic sclerosis (SSc), we hypothesised that IL-23R could be a shared susceptibility gene...