Ying Hu

Summary

Publications

  1. pmc Transcriptome profiling and genome-wide DNA binding define the differential role of fenretinide and all-trans RA in regulating the death and survival of human hepatocellular carcinoma Huh7 cells
    Ying Hu
    Department of Medical Pathology and Laboratory Medicine, 4645 2nd Ave, Research Building III, University of California, Davis Health Systems, Sacramento, CA 95817, USA
    Biochem Pharmacol 85:1007-17. 2013
  2. pmc Forced expression of fibroblast growth factor 21 reverses the sustained impairment of liver regeneration in hPPARα(PAC) mice due to dysregulated bile acid synthesis
    Hui Xin Liu
    Department of Medical Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA, USA
    Oncotarget 6:9686-700. 2015
  3. pmc Bile acids regulate nuclear receptor (Nur77) expression and intracellular location to control proliferation and apoptosis
    Ying Hu
    Department of Medical Pathology and Laboratory Medicine, University of California, Davis Health Systems, Sacramento, California
    Mol Cancer Res 13:281-92. 2015
  4. pmc PPARβ Regulates Liver Regeneration by Modulating Akt and E2f Signaling
    Hui Xin Liu
    Department of Medical Pathology and Laboratory Medicine, University of California, Sacramento, California, United States of America
    PLoS ONE 8:e65644. 2013
  5. pmc Microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration
    Hui Xin Liu
    Department of Medical Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA, USA
    Oncotarget 7:1096-106. 2016
  6. pmc Retinoic acid regulates cell cycle genes and accelerates normal mouse liver regeneration
    Hui Xin Liu
    Department of Medical Pathology and Laboratory Medicine, 4645 2nd Ave, Research Building III, University of California, Davis Health Systems, Sacramento, CA 95817, United States of America Electronic address
    Biochem Pharmacol 91:256-65. 2014
  7. pmc Accelerated partial hepatectomy-induced liver cell proliferation is associated with liver injury in Nur77 knockout mice
    Ying Hu
    Department of Medical Pathology and Laboratory Medicine, University of California, Davis Health Systems, Sacramento, California
    Am J Pathol 184:3272-83. 2014

Collaborators

Detail Information

Publications7

  1. pmc Transcriptome profiling and genome-wide DNA binding define the differential role of fenretinide and all-trans RA in regulating the death and survival of human hepatocellular carcinoma Huh7 cells
    Ying Hu
    Department of Medical Pathology and Laboratory Medicine, 4645 2nd Ave, Research Building III, University of California, Davis Health Systems, Sacramento, CA 95817, USA
    Biochem Pharmacol 85:1007-17. 2013
    ..It provides insight on how retinoid efficacy can be improved and how side effects in cancer therapy can be reduced...
  2. pmc Forced expression of fibroblast growth factor 21 reverses the sustained impairment of liver regeneration in hPPARα(PAC) mice due to dysregulated bile acid synthesis
    Hui Xin Liu
    Department of Medical Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA, USA
    Oncotarget 6:9686-700. 2015
    ..In addition, FGF21 can compensate for the reduced ability of human PPARα in stimulating liver regeneration, which suggests the potential application of FGF21 in promoting hepatic growth in injured and steatotic livers in humans...
  3. pmc Bile acids regulate nuclear receptor (Nur77) expression and intracellular location to control proliferation and apoptosis
    Ying Hu
    Department of Medical Pathology and Laboratory Medicine, University of California, Davis Health Systems, Sacramento, California
    Mol Cancer Res 13:281-92. 2015
    ..These data show for the first time that BAs via Nur77 have a dual role in modulating cell survival and death...
  4. pmc PPARβ Regulates Liver Regeneration by Modulating Akt and E2f Signaling
    Hui Xin Liu
    Department of Medical Pathology and Laboratory Medicine, University of California, Sacramento, California, United States of America
    PLoS ONE 8:e65644. 2013
    ..These data suggested that PPARβ-regulated PDK1/Akt and E2f signaling that controls metabolism and proliferation is involved in the normal progression of liver regeneration...
  5. pmc Microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration
    Hui Xin Liu
    Department of Medical Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA, USA
    Oncotarget 7:1096-106. 2016
    ....
  6. pmc Retinoic acid regulates cell cycle genes and accelerates normal mouse liver regeneration
    Hui Xin Liu
    Department of Medical Pathology and Laboratory Medicine, 4645 2nd Ave, Research Building III, University of California, Davis Health Systems, Sacramento, CA 95817, United States of America Electronic address
    Biochem Pharmacol 91:256-65. 2014
    ..Such effect is associated with an early induction of RA signaling, which includes increased expression of the receptor, binding proteins, and processing enzyme for retinoids. ..
  7. pmc Accelerated partial hepatectomy-induced liver cell proliferation is associated with liver injury in Nur77 knockout mice
    Ying Hu
    Department of Medical Pathology and Laboratory Medicine, University of California, Davis Health Systems, Sacramento, California
    Am J Pathol 184:3272-83. 2014
    ..The accelerated liver regeneration observed in Nur77 KO mice is likely due to a compensatory effect caused by injury. ..