Mona Gupta

Summary

Publications

  1. ncbi request reprint Hydrogel pullulan nanoparticles encapsulating pBUDLacZ plasmid as an efficient gene delivery carrier
    Mona Gupta
    Division of Biochemistry and Molecular Biology, IBLS, Davidson Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    J Control Release 99:157-66. 2004
  2. ncbi request reprint MAP1A light chain 2 interacts with exchange protein activated by cyclic AMP 1 (EPAC1) to enhance Rap1 GTPase activity and cell adhesion
    Mona Gupta
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Davidson Building, Glasgow G12 8QQ, Scotland, United Kingdom
    J Biol Chem 280:8109-16. 2005
  3. ncbi request reprint Microtubule-associated protein 1B-light chain 1 enhances activation of Rap1 by exchange protein activated by cyclic AMP but not intracellular targeting
    Gillian Borland
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom
    Mol Pharmacol 69:374-84. 2006
  4. ncbi request reprint Cytotoxicity suppression and cellular uptake enhancement of surface modified magnetic nanoparticles
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    Biomaterials 26:1565-73. 2005
  5. ncbi request reprint Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
    IEEE Trans Nanobioscience 2:255-61. 2003
  6. ncbi request reprint Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
    Ajay Kumar Gupta
    Crusade Laboratories Limited, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, Scotland, UK
    Biomaterials 26:3995-4021. 2005
  7. ncbi request reprint In vitro cytotoxicity studies of hydrogel pullulan nanoparticles prepared by AOT/N-hexane micellar system
    Mona Gupta
    Division of Biochemistry and Molecular Biology, IBLS, Davidson Building, University of Glasgow, Glasgow, Scotland, United Kingdom
    J Pharm Pharm Sci 7:38-46. 2004
  8. ncbi request reprint Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications
    Ajay Kumar Gupta
    Laboratory for Nanoparticle Research, Formulation and Development Department, Torrent Research Centre, TPL, Village Bhat, Dist Gandhinagar 382 428, Gujarat, India
    Nanomedicine (Lond) 2:23-39. 2007
  9. ncbi request reprint Effect of cellular uptake of gelatin nanoparticles on adhesion, morphology and cytoskeleton organisation of human fibroblasts
    Ajay Kumar Gupta
    Centre for Cell Engineering, IBLS, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    J Control Release 95:197-207. 2004
  10. pmc Exchange protein directly activated by cAMP (EPAC) interacts with the light chain (LC) 2 of MAP1A
    Maria M Magiera
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, Davidson Building, Glasgow G12 8QQ, Scotland, UK
    Biochem J 382:803-10. 2004

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Hydrogel pullulan nanoparticles encapsulating pBUDLacZ plasmid as an efficient gene delivery carrier
    Mona Gupta
    Division of Biochemistry and Molecular Biology, IBLS, Davidson Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    J Control Release 99:157-66. 2004
    ..The results of this study are encouraging for the development of pullulan nanoparticles as an intracellular delivery system for drugs and genes...
  2. ncbi request reprint MAP1A light chain 2 interacts with exchange protein activated by cyclic AMP 1 (EPAC1) to enhance Rap1 GTPase activity and cell adhesion
    Mona Gupta
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Davidson Building, Glasgow G12 8QQ, Scotland, United Kingdom
    J Biol Chem 280:8109-16. 2005
    ..LC2 is therefore a biological enhancer of EPAC1 activity toward Rap1 and associated downstream signaling mechanisms...
  3. ncbi request reprint Microtubule-associated protein 1B-light chain 1 enhances activation of Rap1 by exchange protein activated by cyclic AMP but not intracellular targeting
    Gillian Borland
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom
    Mol Pharmacol 69:374-84. 2006
    ..LC1 is therefore not involved in intracellular targeting of EPAC1, but it is rather a molecular chaperone of EPAC activity toward Rap1...
  4. ncbi request reprint Cytotoxicity suppression and cellular uptake enhancement of surface modified magnetic nanoparticles
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    Biomaterials 26:1565-73. 2005
    ....
  5. ncbi request reprint Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
    IEEE Trans Nanobioscience 2:255-61. 2003
    ..The derivatized nanoparticles show high affinity for cell membrane and opens up new opportunities for magnetic cell separation and recovery that may be of crucial interest for the development of cellular therapies...
  6. ncbi request reprint Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
    Ajay Kumar Gupta
    Crusade Laboratories Limited, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, Scotland, UK
    Biomaterials 26:3995-4021. 2005
    ..This review discusses the synthetic chemistry, fluid stabilization and surface modification of superparamagnetic iron oxide nanoparticles, as well as their use for above biomedical applications...
  7. ncbi request reprint In vitro cytotoxicity studies of hydrogel pullulan nanoparticles prepared by AOT/N-hexane micellar system
    Mona Gupta
    Division of Biochemistry and Molecular Biology, IBLS, Davidson Building, University of Glasgow, Glasgow, Scotland, United Kingdom
    J Pharm Pharm Sci 7:38-46. 2004
    ....
  8. ncbi request reprint Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications
    Ajay Kumar Gupta
    Laboratory for Nanoparticle Research, Formulation and Development Department, Torrent Research Centre, TPL, Village Bhat, Dist Gandhinagar 382 428, Gujarat, India
    Nanomedicine (Lond) 2:23-39. 2007
    ..We have reviewed the various biomedical applications with some of the most recent uses of magnetic nanoparticles for early detection of cancer, diabetes and atherosclerosis...
  9. ncbi request reprint Effect of cellular uptake of gelatin nanoparticles on adhesion, morphology and cytoskeleton organisation of human fibroblasts
    Ajay Kumar Gupta
    Centre for Cell Engineering, IBLS, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    J Control Release 95:197-207. 2004
    ..These studies show that the gelatin nanoparticles prepared by water-in-oil microemulsion systems are endocytosed by the fibroblasts without being toxic to cells even at high concentration of nanoparticles...
  10. pmc Exchange protein directly activated by cAMP (EPAC) interacts with the light chain (LC) 2 of MAP1A
    Maria M Magiera
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, Davidson Building, Glasgow G12 8QQ, Scotland, UK
    Biochem J 382:803-10. 2004
    ..Together with our two-hybrid results, this suggests that the cAMP-binding domain of EPAC1 mediates interaction with LC2...