Evangelia Papadimitriou

Summary

Affiliation: University of Patras
Country: Greece

Publications

  1. doi request reprint Pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta as regulators of angiogenesis and cancer
    Evangelia Papadimitriou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, School of Health Sciences, University of Patras, GR26504 Patras, Greece Electronic address
    Biochim Biophys Acta 1866:252-265. 2016
  2. pmc Transauricular balloon angioplasty in rabbit thoracic aorta: a novel model of experimental restenosis
    Ioanna Koniari
    Cardiothoracic Surgery Department, University Hospital of Patras, Rion Patras zip 25500, Greece
    Lipids Health Dis 13:33. 2014
  3. ncbi request reprint Cell surface nucleolin as a target for anti-cancer therapies
    Marina Koutsioumpa
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504 Patras, Greece
    Recent Pat Anticancer Drug Discov 9:137-52. 2014
  4. pmc Pleiotrophin expression and role in physiological angiogenesis in vivo: potential involvement of nucleolin
    Marina Koutsioumpa
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras GR 26504, Greece
    Vasc Cell 4:4. 2012
  5. ncbi request reprint Heparin affin regulatory peptide: a new target for tumour therapy?
    E Papadimitriou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Greece
    Curr Cancer Drug Targets 4:471-82. 2004
  6. doi request reprint Roles of pleiotrophin in tumor growth and angiogenesis
    Evangelia Papadimitriou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras, Greece
    Eur Cytokine Netw 20:180-90. 2009
  7. pmc Interplay between αvβ3 integrin and nucleolin regulates human endothelial and glioma cell migration
    Marina Koutsioumpa
    Department of Pharmacy, Laboratory of Molecular Pharmacology, University of Patras, Patras, Greece
    J Biol Chem 288:343-54. 2013
  8. ncbi request reprint Heparin affin regulatory peptide/pleiotrophin negatively affects diverse biological activities in C6 glioma cells
    Anastasia Parthymou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504 Patras, Greece
    Eur J Cell Biol 87:17-29. 2008
  9. ncbi request reprint Characterization of heparin affin regulatory peptide signaling in human endothelial cells
    Apostolos Polykratis
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, 26504 Patras, Greece
    J Biol Chem 280:22454-61. 2005
  10. doi request reprint Nitric oxide stimulates migration of human endothelial and prostate cancer cells through up-regulation of pleiotrophin expression and its receptor protein tyrosine phosphatase beta/zeta
    Christos Polytarchou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras, Greece
    Int J Cancer 124:1785-93. 2009

Collaborators

Detail Information

Publications49

  1. doi request reprint Pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta as regulators of angiogenesis and cancer
    Evangelia Papadimitriou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, School of Health Sciences, University of Patras, GR26504 Patras, Greece Electronic address
    Biochim Biophys Acta 1866:252-265. 2016
    ..Insights into the regulatory role of PTN/RPTPβ/ζ on angiogenesis will be extremely beneficial for future development of alternative anti-angiogenic approaches in cancer therapy...
  2. pmc Transauricular balloon angioplasty in rabbit thoracic aorta: a novel model of experimental restenosis
    Ioanna Koniari
    Cardiothoracic Surgery Department, University Hospital of Patras, Rion Patras zip 25500, Greece
    Lipids Health Dis 13:33. 2014
    ..The aim of this study was to demonstrate a percutaneous transauricular method of balloon angioplasty in high-cholesterol fed rabbits, as an innovative atherosclerosis model...
  3. ncbi request reprint Cell surface nucleolin as a target for anti-cancer therapies
    Marina Koutsioumpa
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504 Patras, Greece
    Recent Pat Anticancer Drug Discov 9:137-52. 2014
    ..This review summarizes papers and patents related to the redistribution and the biological functions of cell surface NCL, with emphasis on the potential importance and advantages of developing efficient anti-cell surface NCL strategies. ..
  4. pmc Pleiotrophin expression and role in physiological angiogenesis in vivo: potential involvement of nucleolin
    Marina Koutsioumpa
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras GR 26504, Greece
    Vasc Cell 4:4. 2012
    ..In the present work, we studied expression and functional significance of endogenous PTN during angiogenesis in the chicken embryo chorioallantoic membrane (CAM)...
  5. ncbi request reprint Heparin affin regulatory peptide: a new target for tumour therapy?
    E Papadimitriou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Greece
    Curr Cancer Drug Targets 4:471-82. 2004
    ..It is also constitutively expressed in tumour cell lines and is involved in tumour growth and metastasis. Therefore, HARP appears to be a potential new target for the treatment or/and diagnosis of several types of cancer...
  6. doi request reprint Roles of pleiotrophin in tumor growth and angiogenesis
    Evangelia Papadimitriou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras, Greece
    Eur Cytokine Netw 20:180-90. 2009
    ..In this review, we briefly introduce PTN, and summarize data on its involvement in tumor growth and angiogenesis, and on what is known to date concerning the receptors and pathways involved...
  7. pmc Interplay between αvβ3 integrin and nucleolin regulates human endothelial and glioma cell migration
    Marina Koutsioumpa
    Department of Pharmacy, Laboratory of Molecular Pharmacology, University of Patras, Patras, Greece
    J Biol Chem 288:343-54. 2013
    ....
  8. ncbi request reprint Heparin affin regulatory peptide/pleiotrophin negatively affects diverse biological activities in C6 glioma cells
    Anastasia Parthymou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504 Patras, Greece
    Eur J Cell Biol 87:17-29. 2008
    ..Collectively, these data suggest that HARP negatively affects diverse biological activities in C6 glioma cells, mainly due to binding of HARP to VEGF, which may sequester secreted VEGF from signalling through VEGFR2...
  9. ncbi request reprint Characterization of heparin affin regulatory peptide signaling in human endothelial cells
    Apostolos Polykratis
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, 26504 Patras, Greece
    J Biol Chem 280:22454-61. 2005
    ..These results establish the role of RPTPbeta/zeta as a receptor of HARP in HUVEC and elucidate the HARP signaling pathway in endothelial cells...
  10. doi request reprint Nitric oxide stimulates migration of human endothelial and prostate cancer cells through up-regulation of pleiotrophin expression and its receptor protein tyrosine phosphatase beta/zeta
    Christos Polytarchou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras, Greece
    Int J Cancer 124:1785-93. 2009
    ..The above data suggest that PTN through its receptor RPTPbeta/zeta is a mediator of the stimulatory effects of eNOS/NO on human endothelial and prostate cancer cell migration...
  11. ncbi request reprint Heparin affin regulatory peptide/pleiotrophin mediates fibroblast growth factor 2 stimulatory effects on human prostate cancer cells
    Maria Hatziapostolou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504 Patras, Greece
    J Biol Chem 281:32217-26. 2006
    ....
  12. ncbi request reprint Antioxidants inhibit human endothelial cell functions through down-regulation of endothelial nitric oxide synthase activity
    Christos Polytarchou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504, Greece
    Eur J Pharmacol 510:31-8. 2005
    ..In conclusion, superoxide and hydrogen peroxide seem to play a significant role in promoting endothelial cell proliferation and migration, possibly through regulation of eNOS activity...
  13. ncbi request reprint Hydrogen peroxide stimulates proliferation and migration of human prostate cancer cells through activation of activator protein-1 and up-regulation of the heparin affin regulatory peptide gene
    Christos Polytarchou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR26504 Patras, Greece
    J Biol Chem 280:40428-35. 2005
    ....
  14. doi request reprint A peptide corresponding to the C-terminal region of pleiotrophin inhibits angiogenesis in vivo and in vitro
    Constantinos Mikelis
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras 26504, Greece
    J Cell Biochem 112:1532-43. 2011
    ..Collectively, our data suggest that although PTN(112-136) induces some of the signaling pathways triggered by PTN, it inhibits PTN-induced angiogenic activities through inhibition of PTN binding to α(ν) β(3) integrin...
  15. ncbi request reprint Heparin affin regulatory peptide is a key player in prostate cancer cell growth and angiogenicity
    Maria Hatziapostolou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Greece
    Prostate 65:151-8. 2005
    ..Heparin affin regulatory peptide (HARP) seems to be involved in the progression of several tumors of diverse origin. In the present study, we sought to determine if HARP is implicated in human prostate cancer...
  16. ncbi request reprint Antioxidants modify the effect of X rays on blood vessels
    Christos Polytarchou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504, Greece
    Anticancer Res 26:3043-7. 2006
    ..In the present study, the possible role of reactive oxygen species (ROS) and nitric oxide (NO) in this effect of X rays was evaluated...
  17. doi request reprint Aprotinin stimulates angiogenesis and human endothelial cell migration through the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta
    Marina Koutsioumpa
    Department of Pharmacy, Laboratory of Molecular Pharmacology, University of Patras, Patras, Greece
    Eur J Pharmacol 602:245-9. 2009
    ..The stimulatory effect of aprotinin on pleiotrophin expression and cell migration may explain, at least partly, the problems observed with the clinical use of aprotinin...
  18. ncbi request reprint Serum stimulates Pleiotrophin gene expression in an AP-1-dependent manner in human endothelial and glioblastoma cells
    Evangelia Poimenidi
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504 Patras, Greece
    Anticancer Res 29:349-54. 2009
    ..In the present work, the effect of serum on PTN expression and secretion in the culture medium of human umbilical vein endothelial (HUVECs) and glioblastoma M059K cells was studied...
  19. doi request reprint Pyrrolo[2,3-α]carbazole derivatives as topoisomerase I inhibitors that affect viability of glioma and endothelial cells in vitro and angiogenesis in vivo
    Evgenia Lampropoulou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR26504 Patras, Greece
    Biomed Pharmacother 65:142-50. 2011
    ..These data suggest that the tested pyrrolo[2,3-α]carbazole derivatives inhibit topoisomerase I activity and may be potentially useful for inhibition of glioma cell growth and angiogenesis...
  20. doi request reprint Effect of an all-trans-retinoic acid conjugate with spermine on viability of human prostate cancer and endothelial cells in vitro and angiogenesis in vivo
    Dionissios Vourtsis
    Laboratory of Molecular Pharmacology, Department of Pharmacy, School of Health Sciences, University of Patras, University Campus, Patras GR 26504, Greece
    Eur J Pharmacol 698:122-30. 2013
    ....
  21. doi request reprint Implications of pleiotrophin in human PC3 prostate cancer cell growth in vivo
    Sotiria Tsirmoula
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Greece
    Cancer Sci 103:1826-32. 2012
    ..Our data suggest that PTN is implicated in human prostate cancer growth in vivo and could be considered a potential target for the development of new therapeutic approaches for prostate cancer...
  22. ncbi request reprint Identification of heparin affin regulatory peptide domains with potential role on angiogenesis
    Apostolos Polykratis
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras, GR 26504, Greece
    Int J Biochem Cell Biol 36:1954-66. 2004
    ..Similar results were obtained in vitro with recombinant HARP peptides, identical to the peptides generated after treatment of HARP with plasmin. These results suggest that different regions of HARP may induce or inhibit angiogenesis...
  23. ncbi request reprint Amifostine inhibits angiogenesis in vivo
    Efstathia Giannopoulou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras, Greece
    J Pharmacol Exp Ther 304:729-37. 2003
    ..Such an antiangiogenic action of amifostine, together with its radioprotective effects, further supports its use in combination with radiotherapy for increased therapeutic efficacy...
  24. ncbi request reprint Irradiated C6 glioma cells induce angiogenesis in vivo and activate endothelial cells in vitro
    Anastasia Parthymou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504, Greece
    Int J Cancer 110:807-14. 2004
    ..These results explain at least in part the low effectiveness of radiation therapy of malignant gliomas and support the notion that inhibition of angiogenesis in parallel with radiotherapy may represent a new therapeutic approach...
  25. doi request reprint Heparin-binding protein pleiotrophin: an important player in the angiogenic process
    Constantinos Mikelis
    Department of Pharmacy, Laboratory of Molecular Pharmacology, University of Patras, Patras, Greece
    Connect Tissue Res 49:149-52. 2008
    ..In this minireview, we summarize data on the regulation and mode of action of pleiotrophin and its involvement in physiological and tumor angiogenesis...
  26. ncbi request reprint Soluble guanylyl cyclase activation promotes angiogenesis
    Anastasia Pyriochou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras 26504, Greece
    J Pharmacol Exp Ther 319:663-71. 2006
    ..We conclude that sGC activation promotes the expression of angiogenesis-related properties by EC and that sGC might represent a novel target to modulate neovessel formation...
  27. ncbi request reprint Amifostine has antiangiogenic properties in vitro by changing the redox status of human endothelial cells
    Efstathia Giannopoulou
    Department of Pharmacy, Laboratory of Molecular Pharmacology, University of Patras, GR 26504 Patras, Greece
    Free Radic Res 37:1191-9. 2003
    ..Collectively, our results suggest that amifostine acts on endothelial cells through pathways that affect the redox status of the cells, either by producing H2O2 or by modulating NO production...
  28. ncbi request reprint Perillyl alcohol is an angiogenesis inhibitor
    Heleni Loutrari
    Laboratory for Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras, Greece 26504
    J Pharmacol Exp Ther 311:568-75. 2004
    ..Overall, these data underscore the antiangiogenic potential of POH and suggest that POH, in addition to its anticancer activity, may be an effective agent in the treatment of angiogenesis-dependent diseases...
  29. doi request reprint Effect of conjugates of all-trans-retinoic acid and shorter polyene chain analogues with amino acids on prostate cancer cell growth
    Eldem Sadikoglou
    Department of Pharmacy, Laboratory of Molecular Pharmacology, School of Health Sciences, University of Patras, University Campus, Patras, Greece
    Eur J Med Chem 44:3175-87. 2009
    ..These results demonstrate that compounds 7 and 9 are potentially useful agents that warrant further preclinical development for treatment of prostate cancer...
  30. doi request reprint Integrin alpha(v)beta(3) is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase beta/zeta
    Constantinos Mikelis
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504, Greece
    FASEB J 23:1459-69. 2009
    ..Collectively, these data suggest that alpha(nu)beta(3) is a key molecule that determines the stimulatory or inhibitory effect of PTN on cell migration...
  31. doi request reprint Effects of mechanical loading on the expression of pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta in a rat spinal deformity model
    Angelos Kaspiris
    Laboratory of Molecular Pharmacology, School of Health Sciences, University of Patras, Patras 26504, Greece Laboratory for Research of the Musculoskeletal System, School of Medicine, University of Athens, Athens 14561, Greece
    Cytokine 78:7-15. 2016
    ..Collectively, PTN and RPTPβ/ζ are expressed in spinal deformities caused by mechanical loading, and their expression depends on the type and severity of the applied strain. ..
  32. doi request reprint Macrophage-specific metalloelastase (MMP-12) immunoexpression in the osteochondral unit in osteoarthritis correlates with BMI and disease severity
    Angelos Kaspiris
    Department of Trauma and Orthopaedics, Thriasio General Hospital of Attica NHS, G Gennimata av, Athens, Magoula 19600, Greece Laboratory for Research of the Musculoskeletal System, School of Medicine, University of Athens, Attica, Greece Laboratory of Molecular Pharmacology, School of Health Sciences, University of Patras, Greece Electronic address
    Pathophysiology 22:143-51. 2015
    ..Metalloproteinase 12 (MMP-12) is induced in chondrocytes during fetal development and malignant transformation...
  33. ncbi request reprint Antioxidants inhibit angiogenesis in vivo through down-regulation of nitric oxide synthase expression and activity
    Christos Polytarchou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras, GR 26504, Greece
    Free Radic Res 38:501-8. 2004
    ..These data suggest that antioxidants affect physiological angiogenesis in vivo, through regulation of NOS expression and activity...
  34. ncbi request reprint Pleiotrophin as a possible new target for angiogenesis-related diseases and cancer
    Constantinos Mikelis
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras GR26504, Greece
    Recent Pat Anticancer Drug Discov 2:175-86. 2007
    ..This review summarises papers and patents dealing with the present understanding of PTN biochemistry, actions, mechanism(s) of action and implication in several diseases, with a special emphasis on its role in diverse tumour types...
  35. pmc Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor
    Marina Koutsioumpa
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR, 26504, Patras, Greece
    Mol Cancer 14:19. 2015
    ..In the present work, we studied whether RPTPβ/ζ mediates angiogenic actions of VEGF...
  36. doi request reprint Vascular endothelial growth factor A (VEGF-A) decreases expression and secretion of pleiotrophin in a VEGF receptor-independent manner
    Evangelia Poimenidi
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Greece Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Vascul Pharmacol 80:11-9. 2016
    ..Collectively, these data suggest that VEGF-A down-regulates PTN expression and secretion through the RPTPβ/ζ-ανβ3-NCL axis to enhance its own effect on cell migration and further highlight the role of RPTPβ/ζ in VEGF-A actions. ..
  37. doi request reprint Pleiotrophin-induced endothelial cell migration is regulated by xanthine oxidase-mediated generation of reactive oxygen species
    Sotiria Tsirmoula
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR26504 Patras, Greece
    Microvasc Res 98:74-81. 2015
    ....
  38. doi request reprint Expression of the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta in the serum, cartilage and subchondral bone of patients with osteoarthritis
    Angelos Kaspiris
    Department of Pharmacy, Laboratory of Molecular Pharmacology, University of Patras, Patras GR 26504, Greece
    Joint Bone Spine 80:407-13. 2013
    ..This study aimed to investigate serum pleiotrophin levels and expression of pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta in the cartilage and subchondral bone of osteoarthritis patients...
  39. doi request reprint Pyrrolo[2,3-a]carbazoles as potential cyclin dependent kinase 1 (CDK1) Inhibitors. Synthesis, biological evaluation, and binding mode through docking simulations
    Manolis A Fousteris
    Laboratory of Medicinal Chemistry, Department of Pharmacy, School of Health Sciences, University of Patras, GR 26500 Rion, Patras, Greece
    J Med Chem 51:1048-52. 2008
    ..Using a computational model for CDK1-1e, binding we have observed that 1e exhibited two likely binding modes in the ATP-binding cleft that involve interactions with Lys130, Thr14, and Asp146 of the enzyme...
  40. ncbi request reprint Anticancer activity of cisplatin-loaded PLGA-mPEG nanoparticles on LNCaP prostate cancer cells
    Evangelos C Gryparis
    Laboratory of Pharmaceutical Technology, Department of Pharmacy, University of Patras, Rio, Greece
    Eur J Pharm Biopharm 67:1-8. 2007
    ....
  41. ncbi request reprint Different inhibitors of plasmin differentially affect angiostatin production and angiogenesis
    Maria Hatziapostolou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, Patras GR 26504, Greece
    Eur J Pharmacol 460:1-8. 2003
    ..Moreover, plasmin inhibitors differentially affect in vivo angiogenesis, depending on the mechanism by which they inhibit plasmin activity...
  42. doi request reprint Transcutaneous delivery of a nanoencapsulated antigen: induction of immune responses
    George Mattheolabakis
    Laboratory of Pharmaceutical Technology, Department of Pharmacy, University of Patras, Rio 26500, Greece
    Int J Pharm 385:187-93. 2010
    ..The co-administration of an adjuvant such as CT had the added advantage of modulating the immune response, a desirable characteristic within the context of vaccination against intracellular versus extracellular pathogens...
  43. doi request reprint Microwave-assisted solid-phase peptide synthesis of the 60-110 domain of human pleiotrophin on 2-chlorotrityl resin
    Irene Friligou
    Department of Chemistry, University of Patras, 265 04, Patras, Greece
    Amino Acids 40:1431-40. 2011
    ....
  44. doi request reprint Synthesis and evaluation of condensed magnetic nanocrystal clusters with in vivo multispectral optoacoustic tomography for tumour targeting
    Yiannis Sarigiannis
    Department of Materials Science, University of Patras, 26504 Rio, Greece
    Biomaterials 91:128-39. 2016
    ..It is finally showcased with in vivo multispectral optoacoustic tomography how these properties culminate in a system suitable for targeting breast cancer and for forceful in vivo manipulation with low magnetic field gradients...
  45. doi request reprint A minimally invasive endovascular rabbit model for experimental induction of progressive myocardial hypertrophy
    Grigorios Tsigkas
    Department of Cardiology, School of Medicine, University of Patras, Rion, Greece
    Hypertens Res 39:840-847. 2016
    ..0001) compared with the control animals. In conclusion, this minimally invasive novel technique of transauricular funnel-shaped stent insertion in the descending thoracic aorta may achieve progressive myocardial hypertrophy in rabbits...
  46. doi request reprint Chondroitin sulfate-cell membrane effectors as regulators of growth factor-mediated vascular and cancer cell migration
    Evangelia Pantazaka
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras GR26504, Greece
    Biochim Biophys Acta 1840:2643-50. 2014
    ..Chondroitin sulfate (CS) chains are glycosaminoglycan chains, consisting of disaccharide units of glucuronic acid and N-acetylgalactosamine, attached to proteins as part of proteoglycans...
  47. pmc Epidermal growth factor receptor status and Notch inhibition in non-small cell lung cancer cells
    Efstathia Giannopoulou
    Clinical Oncology Laboratory, Division of Oncology, Department of Medicine, University of Patras, Patras Medical School, Rio, 26504, Greece
    J Biomed Sci 22:98. 2015
    ..H23, A549, H661 and HCC827 human NSCLC cell lines were used, expressing various NICD and EGF receptor (EGFR) protein levels...
  48. ncbi request reprint Arsonoliposomes: effect of arsonolipid acyl chain length and vesicle composition on their toxicity towards cancer and normal cells in culture
    Olga Gortzi
    Department of Pharmacy, University of Patras, Rio 26500, Patras, Greece
    Eur J Pharm Sci 18:175-83. 2003
    ....
  49. ncbi request reprint Amifostine protects blood vessels from the effects of ionizing radiation
    Efstathia Giannopoulou
    Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras, GR 26504 Patras, Greece
    Anticancer Res 22:2821-6. 2002
    ..These data suggest that amifostine protects CAM cells and blood vessels from the effects of X-rays, through mechanisms that do not depend solely on its free radical scavenging properties...