Kalliopi N Manola

Summary

Affiliation: NCSR Demokritos
Country: Greece

Publications

  1. doi request reprint Cytogenetic abnormalities and monosomal karyotypes in children and adolescents with acute myeloid leukemia: correlations with clinical characteristics and outcome
    Kalliopi N Manola
    Department of Cytogenetics, Laboratory of Health Physics and Enviromental Health, NCSR Demokritos Athens, Greece
    Cancer Genet 206:63-72. 2013
  2. doi request reprint Isochromosome der(17)(q10)t(15;17) in acute promyelocytic leukemia resulting in an additional copy of the RARA-PML fusion gene: report of 4 cases and review of the literature
    Kalliopi N Manola
    National Center for Scientific Research Demokritos, Athens, Greece
    Acta Haematol 123:162-70. 2010
  3. doi request reprint Cytogenetics of pediatric acute myeloid leukemia
    Kalliopi N Manola
    Laboratory of Cytogenetics, National Center for Scientific Research, Demokritos, 15310 Aghia Paraskevi, Athens, Greece
    Eur J Haematol 83:391-405. 2009
  4. doi request reprint Jumping translocations in hematological malignancies: a cytogenetic study of five cases
    Kalliopi N Manola
    Laboratory of Cytogenetics, NCSR Demokritos Athens, Greece
    Cancer Genet Cytogenet 187:85-94. 2008
  5. ncbi request reprint Disruption of the ETV6 gene as a consequence of a rare translocation (12;12)(p13;q13) in treatment-induced acute myeloid leukemia after breast cancer
    Kalliopi N Manola
    Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, Terma Patriarchou Grigoriou and Neapoleos, Athens, Greece
    Cancer Genet Cytogenet 180:37-42. 2008
  6. ncbi request reprint Leukemias associated with Turner syndrome: report of three cases and review of the literature
    Kalliopi N Manola
    Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
    Leuk Res 32:481-6. 2008
  7. ncbi request reprint Translocation (X;12)(p11;p13) as a sole abnormality in biphenotypic acute leukemia
    Kalliopi N Manola
    Laboratory of Health Physics and Environmental Hygiene, National Center for Scientific Research NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
    Cancer Genet Cytogenet 173:159-63. 2007
  8. doi request reprint Association of A(313)G glutathione S-transferase P1 germline polymorphism with susceptibility to de novo myelodysplastic syndrome
    Sophia Zachaki
    Laboratory of Health Physics and Environmental Health, NCSR Demokritos, Athens, Greece
    Leuk Lymphoma 54:1756-61. 2013
  9. doi request reprint 5'RARA submicroscopic deletion from new variant translocation involving chromosomes 15, 17, and 18, in a case of acute promyelocytic leukemia
    Chryssa Stavropoulou
    National Center for Scientific Research Demokritos, Athens, Greece
    Cancer Genet Cytogenet 182:50-5. 2008
  10. ncbi request reprint Leukemic recombinations involving heterochromatin in myeloproliferative disorders with t(1;9)
    Constantina Sambani
    Laboratory of Health Physics and Environmental Hygiene, NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
    Cancer Genet Cytogenet 162:45-9. 2005

Collaborators

  • Theodora Koromila
  • Panagoula Kollia
  • Vassiliki Kalotychou
  • Michael Voulgarelis
  • Iwona Wlodarska
  • Georgia I Terzoudi
  • I Kotsianidis
  • Maria Karakosta
  • Sophia Zachaki
  • Aggeliki Daraki
  • Constantina Sambani
  • Chrysa Stavropoulou
  • Gabriel E Pantelias
  • Chryssa Stavropoulou
  • Gregory Kouraklis
  • Emmanuel Kanavakis
  • Marina Kalomoiraki
  • Daphne Koumbi
  • Maria Pagoni
  • Vasileios N Georgakakos
  • Cristina Mecucci
  • Elena Polycarpou
  • Stavroula Gavrili
  • Roberta La Starza
  • Katerina Kakosaiou
  • Eumorfia Maria Delicha
  • Vassiliki Aleporou-Marinou
  • Alkiviadis Kostakis
  • Gabriel Pantelias
  • Paraskevi Diamantopoulou
  • Ioannis Rombos
  • Vasiliki Aleporou
  • Anastasia Athanasiadou
  • Ariadni Mavrou
  • Ioanna Vlachadami
  • Ioannis Korantzis
  • Anastasia Tsakiridou
  • Maria Garofalaki
  • Helen Rigana
  • Juan J Gonzales-Aguilera
  • Peter Vandenberghe
  • Valentina Pierini
  • Nicholas Harhalakis

Detail Information

Publications23

  1. doi request reprint Cytogenetic abnormalities and monosomal karyotypes in children and adolescents with acute myeloid leukemia: correlations with clinical characteristics and outcome
    Kalliopi N Manola
    Department of Cytogenetics, Laboratory of Health Physics and Enviromental Health, NCSR Demokritos Athens, Greece
    Cancer Genet 206:63-72. 2013
    ..These data expand our knowledge by providing novel insights into the cytogenetic features and their correlations with clinical characteristics and outcomes in childhood and adolescent AML...
  2. doi request reprint Isochromosome der(17)(q10)t(15;17) in acute promyelocytic leukemia resulting in an additional copy of the RARA-PML fusion gene: report of 4 cases and review of the literature
    Kalliopi N Manola
    National Center for Scientific Research Demokritos, Athens, Greece
    Acta Haematol 123:162-70. 2010
    ..Cases of overrepresentation of the RARA-PML fusion gene and ider(17q) cases may help in elucidating the role of RARA-PML in leukemogenesis...
  3. doi request reprint Cytogenetics of pediatric acute myeloid leukemia
    Kalliopi N Manola
    Laboratory of Cytogenetics, National Center for Scientific Research, Demokritos, 15310 Aghia Paraskevi, Athens, Greece
    Eur J Haematol 83:391-405. 2009
    ....
  4. doi request reprint Jumping translocations in hematological malignancies: a cytogenetic study of five cases
    Kalliopi N Manola
    Laboratory of Cytogenetics, NCSR Demokritos Athens, Greece
    Cancer Genet Cytogenet 187:85-94. 2008
    ....
  5. ncbi request reprint Disruption of the ETV6 gene as a consequence of a rare translocation (12;12)(p13;q13) in treatment-induced acute myeloid leukemia after breast cancer
    Kalliopi N Manola
    Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, Terma Patriarchou Grigoriou and Neapoleos, Athens, Greece
    Cancer Genet Cytogenet 180:37-42. 2008
    ..To the best of our knowledge, our patient represents the first report of the rare t(12;12)(p13;q13) described in treatment-induced leukemia and the possible formation of a new fusion gene...
  6. ncbi request reprint Leukemias associated with Turner syndrome: report of three cases and review of the literature
    Kalliopi N Manola
    Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
    Leuk Res 32:481-6. 2008
    ....
  7. ncbi request reprint Translocation (X;12)(p11;p13) as a sole abnormality in biphenotypic acute leukemia
    Kalliopi N Manola
    Laboratory of Health Physics and Environmental Hygiene, National Center for Scientific Research NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
    Cancer Genet Cytogenet 173:159-63. 2007
    ..To our knowledge, this cytogenetic aberration has not been reported previously as a sole abnormality in hematological malignancies. Its presence may suggest an important role in the pathogenesis of biphenotypic leukemia...
  8. doi request reprint Association of A(313)G glutathione S-transferase P1 germline polymorphism with susceptibility to de novo myelodysplastic syndrome
    Sophia Zachaki
    Laboratory of Health Physics and Environmental Health, NCSR Demokritos, Athens, Greece
    Leuk Lymphoma 54:1756-61. 2013
    ..007). Our results provide evidence for a pathogenetic role of the GSTP1 polymorphism in MDS risk, probably in an age-dependent manner...
  9. doi request reprint 5'RARA submicroscopic deletion from new variant translocation involving chromosomes 15, 17, and 18, in a case of acute promyelocytic leukemia
    Chryssa Stavropoulou
    National Center for Scientific Research Demokritos, Athens, Greece
    Cancer Genet Cytogenet 182:50-5. 2008
    ..Further cases are needed to delineate the incidence of submicroscopic deletions in APL and elucidate their prognostic impact...
  10. ncbi request reprint Leukemic recombinations involving heterochromatin in myeloproliferative disorders with t(1;9)
    Constantina Sambani
    Laboratory of Health Physics and Environmental Hygiene, NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
    Cancer Genet Cytogenet 162:45-9. 2005
    ..The molecular event underlying juxtaposition of satellite II of chromosome 1 and the satellite III of chromosome 9 remains to be elucidated...
  11. pmc The G⁵¹⁶T CYP2B6 germline polymorphism affects the risk of acute myeloid leukemia and is associated with specific chromosomal abnormalities
    Aggeliki Daraki
    Laboratory of Health Physics, Radiobiology and Cytogenetics, National Centre for Scientific Research NCSR Demokritos, Athens, Greece Department of Genetics and Biotechnology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece
    PLoS ONE 9:e88879. 2014
    ..In conclusion, our results provide evidence for the involvement of the CYP2B6 polymorphism in AML susceptibility and suggest a possible role of the CYP2B6 genetic background on the development of specific chromosomal aberrations...
  12. ncbi request reprint Switch in X-inactivation in a JAK2 V617F-negative case of polycythemia vera with two acquired X-autosome translocations
    Kalliopi N Manola
    Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, 15310 Aghia Paraskevi, Athens, Greece
    Leuk Res 31:1009-14. 2007
    ..3) (second clone). The inactivation of the translocated X chromosomes could provide potential for the inactivation of the adjacent autosomal regions, resulting in epigenetic gene silencing...
  13. doi request reprint High frequency of NAD(P)H:quinone oxidoreductase 1 (NQO1) C(609)T germline polymorphism in MDS/AML with trisomy 8
    Sophia Zachaki
    Laboratory of Health Physics, Radiobiology and Cytogenetics, NCSR Demokritos, Athens, Greece
    Leuk Res 37:742-6. 2013
    ..Interestingly, a 6-fold increased frequency of the homozygous variant genotype was observed among patients with isolated trisomy 8 (p<0.0001), suggesting that null NQO1 activity may influence the occurrence of +8 in MDS/AML...
  14. ncbi request reprint A novel dic(1;10) in a patient with myelodysplastic syndrome
    Constantina Sambani
    Laboratory of Health Physics and Environmental Hygiene, NCSR Demokritos, Athens, Greece
    Cancer Genet Cytogenet 133:87-9. 2002
    ..To our knowledge, a dicentric chromosome involving chromosomes 1 and 10 has never been described in hematological malignancies...
  15. doi request reprint Polymorphisms and haplotypes of the CYP2B6 detoxification gene in the predisposition of Acute Myeloid Leukemia (AML) and induction of its cytogenetic abnormalities
    Aggeliki Daraki
    Laboratory of Health Physics, Radiobiology and Cytogenetics, National Centre for Scientific Research NCSR Demokritos, Athens, Greece Department of Genetics and Biotechnology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece
    Cancer Genet 209:525-533. 2016
    ..Our data suggest that A785G CYP2B6 gene polymorphism and specific CYP2B6 haplotypes may contribute to AML and its specific chromosomal aberrations...
  16. doi request reprint Translocation (6;13)(p21;q14.1) as a rare nonrandom cytogenetic abnormality in chronic lymphocytic leukemia
    Maria Karakosta
    Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, Athens, Greece
    Cancer Genet Cytogenet 198:66-70. 2010
    ..Further studies in more CLL patients are required to delineate the prognostic value of t(6;13)(p21;q14.1) and to identify any candidate genes with potential role in the pathogenesis of the disease...
  17. doi request reprint GSTP1 and CYP2B6 Genetic Polymorphisms and the Risk of Bronchopulmonary Dysplasia in Preterm Neonates
    Sophia Zachaki
    Genesis Genoma Lab, Genetic Diagnosis, Clinical Genetics and Research, Athens, Greece
    Am J Perinatol . 2017
    ..b>Conclusion Our results underscore the significance of both CYP2B6 and GSTP1 polymorphisms in modulating the risk of BPD...
  18. ncbi request reprint G2-checkpoint abrogation in irradiated lymphocytes: A new cytogenetic approach to assess individual radiosensitivity and predisposition to cancer
    Georgia I Terzoudi
    Radiobiology and Cytogenetics, IR RP, National Center for Scientific Research NCSR Demokritos, Athens, Greece
    Int J Oncol 35:1223-30. 2009
    ..Therefore, the proposed methodology using IRP values may provide a clinically applicable predictive assay for individual radiosensitivity and predisposition to cancer...
  19. ncbi request reprint Association of various risk factors with chronic lymphocytic leukemia and its cytogenetic characteristics
    Maria Karakosta
    a Laboratory of Health Physics, Radiobiology and Cytogenetics, National Center for Scientific Research NCSR Demokritos, Athens, Greece
    Arch Environ Occup Health 71:317-329. 2016
    ..Moreover, it indicates the possible involvement of specific occupational and lifestyle risk factors in the onset of CLL...
  20. doi request reprint UGT1A1*28 polymorphism in chronic lymphocytic leukemia: the first investigation of the polymorphism in disease susceptibility and its specific cytogenetic abnormalities
    Maria Karakosta
    Laboratory of Cytogenetics, National Center for Scientific Research NCSR Demokritos, Athens, Greece
    Acta Haematol 132:59-67. 2014
    ..Our study might serve as a starting point to consider UGT1A1*28 polymorphism as one of the possible predisposing factors of CLL pathogenesis...
  21. doi request reprint Cytogenetic abnormalities in acute leukaemia of ambiguous lineage: an overview
    Kalliopi N Manola
    Laboratory of Health Physics and Enviromental Health, Department of Cytogenetics, National Centre for Scientific Research NCSR Demokritos, Aghia Paraskevi, Athens, Greece
    Br J Haematol 163:24-39. 2013
    ..It also summarizes some novel chromosome aberrations that have been observed only once. Furthermore, it highlights the ongoing and future research on ALAL in the field of cytogenetics. ..
  22. doi request reprint Deletion of 5q as a rare abnormality in chronic lymphocytic leukemia
    Maria Karakosta
    Laboratory of Cytogenetics, NCSR Demokritos, Terma Patriarchou Grigoriou and Neapoleos, Aghia Paraskevi, Athens, Greece
    Cancer Genet Cytogenet 200:175-9. 2010
    ....
  23. doi request reprint The parallel application of karyotype interphase and metaphase FISH after DSP-30/IL-2 stimulation is necessary for the investigation of chronic lymphocytic leukemia
    Maria Karakosta
    a Laboratory of Health Physics, Radiobiology and Cytogenetics, NCSR Demokritos, Athens, Greece
    Hematology 21:526-35. 2016
    ....