J Ripoll

Summary

Affiliation: Institute of Molecular Biology and Biotechnology
Country: Greece

Publications

  1. ncbi request reprint Iterative boundary method for diffuse optical tomography
    Jorge Ripoll
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, P O Box 1527, 71110 Heraklion, Greece
    J Opt Soc Am A Opt Image Sci Vis 20:1103-10. 2003
  2. ncbi request reprint In vivo tomographic imaging of near-infrared fluorescent probes
    Vasilis Ntziachristos
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Bldg 149 13th Street 5406, Charlestown, MA 02129 2060, USA
    Mol Imaging 1:82-8. 2002
  3. ncbi request reprint Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography
    Anikitos Garofalakis
    Institute of Electronic Structure and Laser, Foundation for Research and Techinology Hellas, Heraklion Crete, Greece
    Mol Imaging 6:96-107. 2007
  4. ncbi request reprint Kirchhoff approximation for diffusive waves
    J Ripoll
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, P O Box 1527, 71110 Heraklion, Crete, Greece
    Phys Rev E Stat Nonlin Soft Matter Phys 64:051917. 2001
  5. doi request reprint Light, sound, chemistry… action: state of the art optical methods for animal imaging
    Jorge Ripoll
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, Nikolaos Plastira 100, 7110 Heraklion, Greece Electronic
    Drug Discov Today Technol 8:e79-86. 2011
  6. pmc Fluorescence molecular tomography: principles and potential for pharmaceutical research
    Florian Stuker
    Institute for Biomedical Engineering, University and ETH Zurich, Wolfgang Pauli Strasse 10, 8093 Zurich, Switzerland
    Pharmaceutics 3:229-74. 2011
  7. pmc Microscopic optical projection tomography in vivo
    Matthias Rieckher
    Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Crete, Greece
    PLoS ONE 6:e18963. 2011
  8. pmc The impact of stress on tumor growth: peripheral CRF mediates tumor-promoting effects of stress
    Alicia Arranz
    Department of Clinical Chemistry, School of Medicine, University of Crete, 71003 Heraklion, Greece
    Mol Cancer 9:261. 2010
  9. ncbi request reprint Recovery of optical parameters in multiple-layered diffusive media: theory and experiments
    J Ripoll
    Instituto de Ciencia de Materiales de Madrid, Consejo Superior de Investigaciones Cientificas, Spain
    J Opt Soc Am A Opt Image Sci Vis 18:821-30. 2001
  10. doi request reprint Hybrid Fourier-real space method for diffuse optical tomography
    Jorge Ripoll
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, P O Box 1527, Heraklion 71110, Greece
    Opt Lett 35:688-90. 2010

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Iterative boundary method for diffuse optical tomography
    Jorge Ripoll
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, P O Box 1527, 71110 Heraklion, Greece
    J Opt Soc Am A Opt Image Sci Vis 20:1103-10. 2003
    ..Our observations are also contrasted with exact solutions. We furthermore investigate optimal implementation parameters and show that a second-order approximation is appropriate for most in vivo investigations...
  2. ncbi request reprint In vivo tomographic imaging of near-infrared fluorescent probes
    Vasilis Ntziachristos
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Bldg 149 13th Street 5406, Charlestown, MA 02129 2060, USA
    Mol Imaging 1:82-8. 2002
    ..This validation of FMT with FRI demonstrated the spatial congruence of fluorochrome activation as determined by the two techniques...
  3. ncbi request reprint Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography
    Anikitos Garofalakis
    Institute of Electronic Structure and Laser, Foundation for Research and Techinology Hellas, Heraklion Crete, Greece
    Mol Imaging 6:96-107. 2007
    ..The technique was used to image and reconstruct fluorescence originating from 32 x 10(6) T cells in the thymus and 3 x 10(5) T cells in the spleen...
  4. ncbi request reprint Kirchhoff approximation for diffusive waves
    J Ripoll
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, P O Box 1527, 71110 Heraklion, Crete, Greece
    Phys Rev E Stat Nonlin Soft Matter Phys 64:051917. 2001
    ....
  5. doi request reprint Light, sound, chemistry… action: state of the art optical methods for animal imaging
    Jorge Ripoll
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, Nikolaos Plastira 100, 7110 Heraklion, Greece Electronic
    Drug Discov Today Technol 8:e79-86. 2011
    ....
  6. pmc Fluorescence molecular tomography: principles and potential for pharmaceutical research
    Florian Stuker
    Institute for Biomedical Engineering, University and ETH Zurich, Wolfgang Pauli Strasse 10, 8093 Zurich, Switzerland
    Pharmaceutics 3:229-74. 2011
    ..This review shall elucidate the current status and potential of fluorescence tomography including recent advances in multimodality imaging approaches for preclinical and clinical drug development. ..
  7. pmc Microscopic optical projection tomography in vivo
    Matthias Rieckher
    Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Crete, Greece
    PLoS ONE 6:e18963. 2011
    ....
  8. pmc The impact of stress on tumor growth: peripheral CRF mediates tumor-promoting effects of stress
    Alicia Arranz
    Department of Clinical Chemistry, School of Medicine, University of Crete, 71003 Heraklion, Greece
    Mol Cancer 9:261. 2010
    ..The aim of the present study was to assess the significance of peripheral CRF on tumor growth as a mediator of the response to stress in vivo...
  9. ncbi request reprint Recovery of optical parameters in multiple-layered diffusive media: theory and experiments
    J Ripoll
    Instituto de Ciencia de Materiales de Madrid, Consejo Superior de Investigaciones Cientificas, Spain
    J Opt Soc Am A Opt Image Sci Vis 18:821-30. 2001
    ..Finally, we demonstrate the simultaneous retrieval of both mu;(s) and mu(a)...
  10. doi request reprint Hybrid Fourier-real space method for diffuse optical tomography
    Jorge Ripoll
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, P O Box 1527, Heraklion 71110, Greece
    Opt Lett 35:688-90. 2010
    ....
  11. pmc Intravital spectral imaging as a tool for accurate measurement of vascularization in mice
    Alicia Arranz
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, Heraklion 71110, Greece
    J Angiogenes Res 2:22. 2010
    ..However, in most cases a high throughput technique that is simple, accurate, user-independent and cost-effective for small animal imaging is not available...
  12. doi request reprint Derivation of the scalar radiative transfer equation from energy conservation of Maxwell's equations in the far field
    Jorge Ripoll
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, N Plastira 100, 71110 Heraklion, Greece
    J Opt Soc Am A Opt Image Sci Vis 28:1765-75. 2011
    ....
  13. ncbi request reprint Experimental determination of photon propagation in highly absorbing and scattering media
    Jorge Ripoll
    Institute of Electronic Structure and Laser, Foundation for Research and Technology Hellas, Heraklion, Crete, Greece
    J Opt Soc Am A Opt Image Sci Vis 22:546-51. 2005
    ....
  14. doi request reprint 3D multi-modal registration for assessing molecular activity changes in time-dependent geometries
    Madelen Andersson
    Institute of Computer Science, Foundation for Research and Technology FORTH, Heraklion, Greece
    Conf Proc IEEE Eng Med Biol Soc 2008:3975-8. 2008
    ..It can be further extended to other imaging modalities, as well...
  15. ncbi request reprint Optical characterization of thin female breast biopsies based on the reduced scattering coefficient
    A Garofalakis
    Institute of Electronic Structure and Laser, Foundation for Research and Technology Hellas, PO Box 1527, 71110 Heraklion, Greece
    Phys Med Biol 50:2583-96. 2005
    ..The mean values for the reduced scattering coefficients of the normal and the tumour tissue were measured to be 9.7 +/- 2.2 cm(-1) and 10.8 +/- 1.8 cm(-1), respectively. The correlation with age was also investigated...
  16. ncbi request reprint Noncontact optical imaging in mice with full angular coverage and automatic surface extraction
    Heiko Meyer
    Institute of Electronic Structure and Laser, Foundation for Research and Technology Hellas, Heraklion Crete, Greece
    Appl Opt 46:3617-27. 2007
    ..Finally, the potential use of this setup for in vivo small animal imaging and its impact on biomedical research is discussed...
  17. ncbi request reprint Normalized transillumination of fluorescent proteins in small animals
    Giannis Zacharakis
    Harvard Medical School, MA, USA
    Mol Imaging 5:153-9. 2006
    ..Due to the balance achieved between simplicity and accuracy, normalized transillumination approaches could serve as an important alternative molecular imaging method...
  18. ncbi request reprint Free-space propagation of diffuse light: theory and experiments
    Jorge Ripoll
    Institute for Electronic Structure and Laser, Foundation for Research and Technology Hellas, P O Box 1527, 71110 Heraklion, Greece
    Phys Rev Lett 91:103901. 2003
    ..The implications of this new formulation in the context of optical tomography in turbid media are discussed...
  19. doi request reprint Investigation of binding mechanisms of nuclear proteins using confocal scanning laser microscopy and FRAP
    George D Tsibidis
    Institute of Electronic Structure and Laser, Foundation for Research and Technology, P O Box 1385, Vassilika Vouton, 71110 Heraklion, Crete, Greece
    J Theor Biol 253:755-68. 2008
    ..The theoretical model can be used in conjunction to experimental data acquired by CSLM to investigate the biophysical properties of proteins in living cells...
  20. ncbi request reprint Image analysis for assessing molecular activity changes in time-dependent geometries
    Kostas Marias
    Medical Vision Laboratory, Department of Engineering Science, Oxford University, Oxford OX1 3PJ, UK
    IEEE Trans Med Imaging 24:894-900. 2005
    ..The method can account for differences in the positioning and compression of small animals and can be extended to three-dimensional as well as to other imaging modalities...
  21. ncbi request reprint Fluorescent protein tomography scanner for small animal imaging
    Giannis Zacharakis
    Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    IEEE Trans Med Imaging 24:878-85. 2005
    ..We conclude that the method could be applied in tomographic imaging of fluorescent proteins for in vivo targeting of different diseases and abnormalities...
  22. doi request reprint Weighted filtered backprojection for quantitative fluorescence optical projection tomography
    A Darrell
    BMI Laboratory, Institute of Computer Science, Foundation for Research and Technology Hellas, Vassilika Vouton, PO Box 1385, GR 711 10 Heraklion, Greece
    Phys Med Biol 53:3863-81. 2008
    ..This new algorithm is tested with simulated data and with experimental data from a phantom consisting of fluorescent microspheres embedded in an agarose gel...
  23. doi request reprint Source intensity profile in noncontact optical tomography
    Ana Sarasa-Renedo
    Foundation for Research and Technology Hellas, P O Box 1527, Heraklion 71110, Greece
    Opt Lett 35:34-6. 2010
    ..We show how this approach improves image quality and resolution, while considerably simplifying the forward and inverse problems of the image reconstruction process...
  24. ncbi request reprint Quantitative point source photoacoustic inversion formulas for scattering and absorbing media
    Jorge Ripoll
    Institute for Electronic Structure and Laser Foundation for Research and Technology Hellas, Heraklion, Greece
    Phys Rev E Stat Nonlin Soft Matter Phys 71:031912. 2005
    ..The proposed system could retrieve absorption information using photoacoustic measurements, and use these data to more accurately describe the fluorescence problem and improve reconstruction fidelity...
  25. ncbi request reprint Singular-value analysis and optimization of experimental parameters in fluorescence molecular tomography
    Edward E Graves
    Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Room 5404, Charlestown, Massachusetts 02129, USA
    J Opt Soc Am A Opt Image Sci Vis 21:231-41. 2004
    ....
  26. ncbi request reprint In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green
    Xavier Intes
    Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Med Phys 30:1039-47. 2003
    ..These results provide further evidence that in vivo pharmacokinetics of ICG in breast tumors may be a useful diagnostic tool for differentiation of benign and malignant pathologies...
  27. ncbi request reprint Noncontact optical tomography of turbid media
    Ralf B Schulz
    Laboratory for Bio optics and Molecular Imaging, Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Suite 5209, Charlestown, Massachusetts 02129, USA
    Opt Lett 28:1701-3. 2003
    ..This approach offers significant experimental simplicity and yields high-information-content datasets. The performance of this novel tomographic approach is demonstrated with experimental reconstructions of phantoms...
  28. doi request reprint Surface Reconstruction for free-space 360 degrees fluorescence molecular tomography and the effects of animal motion
    Tobias Lasser
    Laboratory for Bio optics and Molecular Imaging, Center for Molecular Imaging Research, Massachusetts General Hosiptal and Harvard Medical School, Charlestown, MA 02129, USA
    IEEE Trans Med Imaging 27:188-94. 2008
    ..We then employ this methodology to characterize the animal movement of anaesthetized animals. We find that the effects of animal movement on the FMT reconstructed image were within system resolution limits (approximately 0.07 cm)...
  29. ncbi request reprint Looking and listening to light: the evolution of whole-body photonic imaging
    Vasilis Ntziachristos
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School CNY149, 13th Street 5406, Charlestown, Massachusetts 02129, USA
    Nat Biotechnol 23:313-20. 2005
    ..For photonic imaging to fully realize its potential, however, further progress will be needed in refining optical inversion methods and data acquisition techniques...
  30. pmc Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate
    Vasilis Ntziachristos
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 101:12294-9. 2004
    ..Tomographic approaches are found essential for small-animal optical imaging and are potentially well suited for clinical drug development and monitoring...
  31. ncbi request reprint Accuracy of fluorescent tomography in the presence of heterogeneities: study of the normalized Born ratio
    Antoine Soubret
    Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    IEEE Trans Med Imaging 24:1377-86. 2005
    ..Findings are further contrasted to images obtained with the standard Born expansion and with a normalized approach that divides the fluorescent field with excitation measurements through a homogeneous medium...
  32. ncbi request reprint Experimental fluorescence tomography of tissues with noncontact measurements
    Ralf B Schulz
    Department of Medical Physics in Radiology, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    IEEE Trans Med Imaging 23:492-500. 2004
    ..In this paper, we describe the experimental implementation of this novel concept and demonstrate capacity to perform small animal imaging...
  33. ncbi request reprint Planar fluorescence imaging using normalized data
    Vasilis Ntziachristos
    Massachusetts General Hospital and Harvard Medical School, Center for Molecular Imaging Research, Laboratory for Biooptics and Molecular Imaging, Charlestown, Massachusetts 02129, USA
    J Biomed Opt 10:064007. 2005
    ..Normalized planar imaging retains implementation simplicity and could be used to improve on standard fluorescence reflectance imaging and as a simplified alternative to the more integrated and accurate tomographic methods...
  34. ncbi request reprint Diffuse photon propagation in multilayered geometries
    Jan Sikora
    Institute of the Theory of Electrical Engineering, Measurement and Information Systems, Warsaw University of Technology, Koszykowa 75, 00 661 Warsaw, Poland
    Phys Med Biol 51:497-516. 2006
    ..Results are presented comparing these solutions to an independent Monte Carlo model, and for an example three layered head model...
  35. ncbi request reprint Free-space fluorescence molecular tomography utilizing 360 degrees geometry projections
    Nikolaos Deliolanis
    Laboratory for Biooptics and Molecular Imaging, Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
    Opt Lett 32:382-4. 2007
    ..Reconstruction feasibility using 36 projections in 10 degrees steps is demonstrated in mice...
  36. ncbi request reprint Complete-angle projection diffuse optical tomography by use of early photons
    Gordon M Turner
    Laboratory for Bio optics and Molecular Imaging, Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Opt Lett 30:409-11. 2005
    ..The appropriateness of reconstruction algorithms similar to those employed in x-ray computed tomography are showcased, and suggestions for model improvements are provided...
  37. pmc Volumetric tomography of fluorescent proteins through small animals in vivo
    Giannis Zacharakis
    Laboratory for Bio optics and Molecular Imaging, Center for Molecular Imaging Research, Harvard Medical School, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 102:18252-7. 2005
    ..This technology can significantly improve imaging capacity over the current state of the art and should find wide in vivo imaging applications in drug discovery, immunology, and cancer research...