Athanassios Tsakris

Summary

Affiliation: Aristotle University of Thessaloniki
Country: Greece

Publications

  1. ncbi Leg ulcer due to Pseudomanas luteola in a patient with sickle cell disease
    Athanassios Tsakris
    Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Diagn Microbiol Infect Dis 42:141-3. 2002
  2. pmc Apparent increased prevalence of high-level aminoglycoside-resistant Enterococcus durans resulting from false identification by a semiautomated software system
    A Tsakris
    Department of Microbiology, Medical School, Aristotelian University of Thessaloniki, Greece
    J Clin Microbiol 36:1419-21. 1998
  3. ncbi Infrequent detection of acquired metallo-beta-lactamases among carbapenem-resistant Pseudomonas isolates in a Greek hospital
    A Tsakris
    First Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Clin Microbiol Infect 9:846-51. 2003
  4. ncbi Increasing prevalence of high-level gentamicin resistance among Enterococci isolated in Greece
    A Tsakris
    Department of Microbiology, Medical School, Aristotle University of Thessaloniki, GR 54 006 Thessaloniki, Greece
    Chemotherapy 47:86-9. 2001
  5. pmc Pseudo-outbreak of imipenem-resistant Acinetobacter baumannii resulting from false susceptibility testing by a rapid automated system
    A Tsakris
    Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
    J Clin Microbiol 38:3505-7. 2000
  6. pmc Outbreak of infections caused by Pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece
    A Tsakris
    Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54 006 Thessaloniki, Greece
    J Clin Microbiol 38:1290-2. 2000
  7. ncbi In-vitro activity of antibiotics against Legionella pneumophila isolates from water systems
    A Tsakris
    Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54 006 Thessaloniki, Greece
    J Antimicrob Chemother 44:693-5. 1999
  8. doi First occurrence of KPC-2-possessing Klebsiella pneumoniae in a Greek hospital and recommendation for detection with boronic acid disc tests
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Antimicrob Chemother 62:1257-60. 2008
  9. pmc Large dissemination of VIM-2-metallo-{beta}-lactamase-producing pseudomonas aeruginosa strains causing health care-associated community-onset infections
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, 75 Mikras Asias Street, 11527 Athens, Greece
    J Clin Microbiol 47:3524-9. 2009
  10. pmc Outbreak caused by an ertapenem-resistant, CTX-M-15-producing Klebsiella pneumoniae sequence type 101 clone carrying an OmpK36 porin variant
    Aggeliki Poulou
    Department of Microbiology, Serres General Hospital, Serres, Greece
    J Clin Microbiol 51:3176-82. 2013

Collaborators

Detail Information

Publications89

  1. ncbi Leg ulcer due to Pseudomanas luteola in a patient with sickle cell disease
    Athanassios Tsakris
    Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Diagn Microbiol Infect Dis 42:141-3. 2002
    ..This report describes the first case of deteriorated leg ulcer caused by a multiply antibiotic resistant P. luteola strain in a patient with homozygous sickle cell disease...
  2. pmc Apparent increased prevalence of high-level aminoglycoside-resistant Enterococcus durans resulting from false identification by a semiautomated software system
    A Tsakris
    Department of Microbiology, Medical School, Aristotelian University of Thessaloniki, Greece
    J Clin Microbiol 36:1419-21. 1998
    ..Antibiotic resistance and pulsed-field gel electrophoresis patterns showed that unrelated strains were misidentified...
  3. ncbi Infrequent detection of acquired metallo-beta-lactamases among carbapenem-resistant Pseudomonas isolates in a Greek hospital
    A Tsakris
    First Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Clin Microbiol Infect 9:846-51. 2003
    ..To study the possible distribution of metallo-beta-lactamases among nosocomial Pseudomonas isolates in a Greek hospital with a recent high prevalence of carbapenem-resistant Pseudomonas isolates...
  4. ncbi Increasing prevalence of high-level gentamicin resistance among Enterococci isolated in Greece
    A Tsakris
    Department of Microbiology, Medical School, Aristotle University of Thessaloniki, GR 54 006 Thessaloniki, Greece
    Chemotherapy 47:86-9. 2001
    ..All transconjugants acquired high-level resistance to streptomycin. HLGRE cause therapeutic problems in our region, since none of the clinically available aminoglycosides can be used in severe infections...
  5. pmc Pseudo-outbreak of imipenem-resistant Acinetobacter baumannii resulting from false susceptibility testing by a rapid automated system
    A Tsakris
    Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
    J Clin Microbiol 38:3505-7. 2000
    ..The pseudoresistant acinetobacters did not form a genetically homogeneous group. It is suggested that the detection of imipenem-resistant A. baumannii isolates by this system should be confirmed by an additional susceptibility test...
  6. pmc Outbreak of infections caused by Pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece
    A Tsakris
    Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54 006 Thessaloniki, Greece
    J Clin Microbiol 38:1290-2. 2000
    ..bla(VIM)-bearing isolates belonged to serotype O:12 and were indistinguishable by pulsed-field gel electrophoresis...
  7. ncbi In-vitro activity of antibiotics against Legionella pneumophila isolates from water systems
    A Tsakris
    Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54 006 Thessaloniki, Greece
    J Antimicrob Chemother 44:693-5. 1999
    ..06-0.5 mg/L) and rifampicin (MICs < or = 0.007-0.015 mg/L). It seems that antibiotics used for legionellosis continue to exhibit good activity against L. pneumophila isolates from environmental sources in European countries...
  8. doi First occurrence of KPC-2-possessing Klebsiella pneumoniae in a Greek hospital and recommendation for detection with boronic acid disc tests
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Antimicrob Chemother 62:1257-60. 2008
    ..To investigate the first KPC carbapenemase-producing Klebsiella pneumoniae isolate from a Greek hospital, including phenotypic methods to aid recognition of this resistance type...
  9. pmc Large dissemination of VIM-2-metallo-{beta}-lactamase-producing pseudomonas aeruginosa strains causing health care-associated community-onset infections
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, 75 Mikras Asias Street, 11527 Athens, Greece
    J Clin Microbiol 47:3524-9. 2009
    ..The high rate of recurrent infections in the community underlies the difficulty of constraining infections caused by such microorganisms in the extrahospital setting...
  10. pmc Outbreak caused by an ertapenem-resistant, CTX-M-15-producing Klebsiella pneumoniae sequence type 101 clone carrying an OmpK36 porin variant
    Aggeliki Poulou
    Department of Microbiology, Serres General Hospital, Serres, Greece
    J Clin Microbiol 51:3176-82. 2013
    ..Identification of hidden carriers upon admission and by screening on a weekly basis was found valuable for early recognition and subsequent successful management of the outbreak. ..
  11. pmc Comparative evaluation of a prototype chromogenic medium (ChromID CARBA) for detecting carbapenemase-producing Enterobacteriaceae in surveillance rectal swabs
    Georgia Vrioni
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Clin Microbiol 50:1841-6. 2012
    ..9%) and ESBL-BH (93.2%) than for CDC-TS (86.4%), MCM (85.2%), and chromID ESBL (84.7%) (P = 0.014). In conclusion, chromID CARBA was found to be a rapid and accurate culture screening method for active CPE surveillance...
  12. doi Intensive care unit dissemination of multiple clones of linezolid-resistant Enterococcus faecalis and Enterococcus faecium
    Eleni Ntokou
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    J Antimicrob Chemother 67:1819-23. 2012
    ..Outbreaks caused by linezolid-resistant (LR) enterococci remain rare. We report the epidemiological and molecular characteristics of the multiclonal dissemination of LR enterococci in the intensive care unit (ICU) of a Greek hospital...
  13. doi Detection of the new metallo-beta-lactamase VIM-19 along with KPC-2, CMY-2 and CTX-M-15 in Klebsiella pneumoniae
    Spyros Pournaras
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    J Antimicrob Chemother 65:1604-7. 2010
    ..To report the identification of the metallo-beta-lactamase (MBL) variant VIM-19 in a Klebsiella pneumoniae clinical strain co-producing KPC-2 carbapenemase, CMY-2 cephalosporinase and CTX-M-15 extended-spectrum beta-lactamase...
  14. pmc Characteristics of meropenem heteroresistance in Klebsiella pneumoniae carbapenemase (KPC)-producing clinical isolates of K. pneumoniae
    Spyros Pournaras
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    J Clin Microbiol 48:2601-4. 2010
    ..Time-kill assays indicated that meropenem alone was not bactericidal against KPC-KP but efficiently killed the control strains...
  15. pmc Outbreak caused by a multidrug-resistant Klebsiella pneumoniae clone carrying blaVIM-12 in a university hospital
    Despina Tokatlidou
    Department of Clinical Microbiology, Hippokration General Hospital, Thessaloniki, Greece
    J Clin Microbiol 46:1005-8. 2008
    ..Pulsed-field gel electrophoresis demonstrated a single macrorestriction pattern, indicating the clonal spread of VIM-12-producing K. pneumoniae...
  16. pmc Comparative evaluation of combined-disk tests using different boronic acid compounds for detection of klebsiella pneumoniae carbapenemase-producing enterobacteriaceae clinical isolates
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, 11527 Athens, Greece
    J Clin Microbiol 49:2804-9. 2011
    ..6%). This comparative study showed that PBA is the most effective inhibitor of KPC enzymes, and its use in combined-disk tests with meropenem may give the most easily interpreted results...
  17. doi Activity of tigecycline alone and in combination with colistin and meropenem against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae strains by time-kill assay
    Spyros Pournaras
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    Int J Antimicrob Agents 37:244-7. 2011
    ..Additional in vivo tests are warranted to assess better the killing kinetics of tigecycline combinations against KPC-producers...
  18. pmc Risk factors and outcomes associated with acquisition of colistin-resistant KPC-producing Klebsiella pneumoniae: a matched case-control study
    Olympia Zarkotou
    Department of Microbiology, Tzaneio General Hospital, Piraeus, Greece
    J Clin Microbiol 48:2271-4. 2010
    ..None of these parameters independently predicted colistin resistance, which probably occurred in a susceptible KPC-KP strain that was subsequently disseminated horizontally...
  19. doi Clonal spread of KPC-2 carbapenemase-producing Klebsiella pneumoniae strains in Greece
    Spyros Pournaras
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    J Antimicrob Chemother 64:348-52. 2009
    ..KPC-possessing Klebsiella pneumoniae have been found to be widespread in several regions but are still rarely detected in Europe. We describe the characteristics of an outbreak caused by KPC producers in a tertiary care Greek hospital...
  20. doi Susceptibility patterns to extended-spectrum cephalosporins among Enterobacteriaceae harbouring extended-spectrum β-lactamases using the updated Clinical and Laboratory Standards Institute interpretive criteria
    Ioulia Kristo
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    Int J Antimicrob Agents 41:383-7. 2013
    ....
  21. doi Recurrent healthcare-associated community-onset infections due to Klebsiella pneumoniae producing VIM-1 metallo-beta-lactamase
    Aggeliki Poulou
    Department of Microbiology, Serres General Hospital, Serres, Greece
    J Antimicrob Chemother 65:2538-42. 2010
    ..To investigate the extrahospital dissemination of carbapenem-resistant Klebsiella pneumoniae isolates and the mechanisms of acquired resistance...
  22. pmc Use of boronic acid disk tests to detect extended- spectrum beta-lactamases in clinical isolates of KPC carbapenemase-possessing enterobacteriaceae
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, Athens 11527, Greece
    J Clin Microbiol 47:3420-6. 2009
    ..Our results demonstrate that the modified CLSI ESBL confirmatory test with antibiotic disks containing BA is the most accurate phenotypic method for the detection of ESBLs in Enterobacteriaceae producing KPC carbapenemases...
  23. ncbi Transmission in the community of clonal Proteus mirabilis carrying VIM-1 metallo-beta-lactamase
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Antimicrob Chemother 60:136-9. 2007
    ..The aim of the study was to investigate this extrahospital dissemination and the mechanisms of resistance to carbapenems...
  24. doi A simple phenotypic method for the differentiation of metallo-beta-lactamases and class A KPC carbapenemases in Enterobacteriaceae clinical isolates
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Antimicrob Chemother 65:1664-71. 2010
    ..The increasing frequency of class A KPC enzymes and class B metallo-beta-lactamases (MBLs) among Enterobacteriaceae as well as their possible co-production makes their early differentiation urgent...
  25. doi Evolution of multidrug-resistant Acinetobacter baumannii clonal lineages: a 10 year study in Greece (2000-09)
    Vasiliki Gogou
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    J Antimicrob Chemother 66:2767-72. 2011
    ..To analyse the evolution and genetic relatedness of Acinetobacter baumannii clonal lineages in Greece during a 10 year period...
  26. pmc Evaluation of boronic acid disk tests for differentiating KPC-possessing Klebsiella pneumoniae isolates in the clinical laboratory
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Clin Microbiol 47:362-7. 2009
    ..3%). These practical and simple boronic acid disk tests promise to be very helpful for the accurate differentiation of KPC-possessing K. pneumoniae isolates, even in regions where different broad-spectrum beta-lactamases are widespread...
  27. doi Detection of cytomegalovirus, parvovirus B19 and herpes simplex viruses in cases of intrauterine fetal death: association with pathological findings
    Garyfallia Syridou
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Med Virol 80:1776-82. 2008
    ..Fetal hydrops and chronic villitis were evidently associated with viral DNA detection in cases of intrauterine death...
  28. pmc In vivo acquisition of a plasmid-mediated bla(KPC-2) gene among clonal isolates of Serratia marcescens
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Clin Microbiol 48:2546-9. 2010
    ..marcescens isolates. Molecular typing and plasmid analysis suggested that all three patients had clonally indistinguishable isolates of S. marcescens that acquired a plasmid-mediated bla(KPC-2) gene during the hospitalization...
  29. pmc VIM-1 metallo-beta-lactamase in Acinetobacter baumannii
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    Emerg Infect Dis 12:981-3. 2006
    ..VIM-1 MBL in Acinetobacter spp. causes concern, given the increasing resistance of this species...
  30. pmc A combined disk test for direct differentiation of carbapenemase-producing enterobacteriaceae in surveillance rectal swabs
    Spyros Pournaras
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Clin Microbiol 51:2986-90. 2013
    ....
  31. doi Detection of a phylogenetically distinct IMP-type metallo-β-lactamase, IMP-35, in a CC235 Pseudomonas aeruginosa from the Dutch-German border region (Euregio)
    Spyros Pournaras
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    J Antimicrob Chemother 68:1271-6. 2013
    ..To characterize a highly divergent IMP-type metallo-β-lactamase (MBL) variant detected in a multidrug-resistant Pseudomonas aeruginosa clinical isolate...
  32. pmc Linezolid dependence in Staphylococcus epidermidis bloodstream isolates
    Spyros Pournaras
    Department of Microbiology, University of Thessaly Medical School, Larissa, Greece
    Emerg Infect Dis 19:129-32. 2013
    ..These isolates carried the mutations T2504A and C2534T in multiple 23S rRNA copies and 2 mutations leading to relevant amino acid substitutions in L3 protein. Linezolid dependence could account for increasing LRSE emergence...
  33. pmc Comparative evaluation of tigecycline susceptibility testing methods for expanded-spectrum cephalosporin- and carbapenem-resistant gram-negative pathogens
    Olympia Zarkotou
    Department of Microbiology, Tzaneio General Hospital, Piraeus, Greece
    J Clin Microbiol 50:3747-50. 2012
    ..4/0.8% major errors, and MTS produced no major errors but 0.4/3.3% very major errors (FDA/EUCAST breakpoints). Vitek2 tigecycline results require confirmation by BMD or Etest for multidrug-resistant pathogens...
  34. doi Detection of Pseudomonas aeruginosa isolates of the international clonal complex 11 carrying the blaPER-1 extended-spectrum β-lactamase gene in Greece
    Kyriaki Ranellou
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Antimicrob Chemother 67:357-61. 2012
    ..Despite reports from other European countries, such strains have not been detected in Greece until now. We describe the first bla(PER-1)-positive P. aeruginosa isolates from Greece and their genetic environment...
  35. doi Epidemiological characteristics of infections caused by Bacteroides, Prevotella and Fusobacterium species: a prospective observational study
    Joseph Papaparaskevas
    Department of Microbiology, Medical School, National and Kapodistrian University of Athens, Greece
    Anaerobe 17:113-7. 2011
    ....
  36. ncbi Efflux system overexpression and decreased OprD contribute to the carbapenem heterogeneity in Pseudomonas aeruginosa
    Alexandros Ikonomidis
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    FEMS Microbiol Lett 279:36-9. 2008
    ..05) and decreased intensity of the protein band of the porin OprD. Upregulation of efflux systems, in part, and the decrease of OprD contribute to the heterogeneous growth against carbapenems in our P. aeruginosa clinical isolates...
  37. pmc Imported Klebsiella pneumoniae carbapenemase-producing K. pneumoniae clones in a Greek hospital: impact of infection control measures for restraining their dissemination
    Aggeliki Poulou
    Department of Microbiology, Serres General Hospital, Serres, Greece
    J Clin Microbiol 50:2618-23. 2012
    ..058) and to 0.1/1,000 patient days in 2011 (P = 0.0012). Our findings suggest that rigorous infection control measures and active surveillance can effectively reduce the incidence of secondary transmission due to KPC-producing pathogens...
  38. doi Inhibitor-based methods for the detection of KPC carbapenemase-producing Enterobacteriaceae in clinical practice by using boronic acid compounds
    Spyros Pournaras
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    J Antimicrob Chemother 65:1319-21. 2010
    ..We think that they could effectively replace MHT for the convenient and early detection of KPC carbapenemases in regions where these enzymes are common...
  39. pmc Hidden VIM-1 metallo-beta-lactamase phenotypes among Acinetobacter baumannii clinical isolates
    Alexandros Ikonomidis
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    J Clin Microbiol 46:346-9. 2008
    ..One isolate had bla(VIM-1) preceded by a weak P1 promoter, and both had inactivated P2 promoters and reduced bla(VIM-1) expression, partially justifying the results revealing hidden MBL phenotypes...
  40. ncbi Characterization of In3Mor, a new integron carrying VIM-1 metallo-beta-lactamase and sat1 gene, from Morganella morganii
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Antimicrob Chemother 59:739-41. 2007
    ..The aim of the study was to analyse the structure of the integron containing the MBL gene...
  41. pmc Outbreaks in distinct regions due to a single Klebsiella pneumoniae clone carrying a bla VIM-1 metallo-{beta}-lactamase gene
    Alexandros Ikonomidis
    Department of Medical Microbiology, Medical School, University Hospital of Thessaly, Mezourlo, 411 10 Larissa, Greece
    J Clin Microbiol 43:5344-7. 2005
    ..The clonal spread of VIM-1-producing K. pneumoniae strains in distinct regions where up to now bla(VIM-2) and bla(VIM-4) alleles were common is worrisome...
  42. pmc Dissemination of clinical isolates of Klebsiella oxytoca harboring CMY-31, VIM-1, and a New OXY-2-type variant in the community
    Athanassios Tsakris
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    Antimicrob Agents Chemother 55:3164-8. 2011
    ..This is the first study to present the dissemination in the community of multidrug-resistant K. oxytoca isolates causing extrahospital infections...
  43. doi Outbreak of OXA-48 carbapenemase-producing Klebsiella pneumoniae in Greece involving an ST11 clone
    Evangelia Voulgari
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Antimicrob Chemother 68:84-8. 2013
    ..Despite reports from other European regions, until now no such isolates have been detected in Greece. We describe the characteristics of the first outbreak caused by OXA-48-producing Klebsiella pneumoniae in Greece...
  44. doi Adenovirus genome in the placenta: association with histological chorioamnionitis and preterm birth
    Effrossine A Tsekoura
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    J Med Virol 82:1379-83. 2010
    ..026) as well as compared to term adenovirus-positive placentas (75% vs. 19%; P = 0.003). This study demonstrates that adenovirus infection of the placenta is associated strongly with histological chorioamnionitis and preterm birth...
  45. pmc Emergence of OXA-162 Carbapenemase- and DHA-1 AmpC Cephalosporinase-Producing Sequence Type 11 Klebsiella pneumoniae Causing Community-Onset Infection in Greece
    Evangelia Voulgari
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    Antimicrob Agents Chemother 60:1862-4. 2015
    ..They belonged to a single sequence type (ST11) and caused the first documented community-onset urinary tract infections attributable to an OXA-48-like-producing Enterobacteriaceae strain. ..
  46. doi Carbapenemase-producing Enterobacteriaceae: now that the storm is finally here, how will timely detection help us fight back?
    Evangelia Voulgari
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    Future Microbiol 8:27-39. 2013
    ....
  47. doi Association of biofilm formation and methicillin-resistance with accessory gene regulator (agr) loci in Greek Staphylococcus aureus clones
    Alexandros Ikonomidis
    Department of Microbiology, University of Thessaly, University Hospital of Larissa, Greece
    Microb Pathog 47:341-4. 2009
    ..These findings suggest that agr Group II is simultaneously associated with methicillin-resistance and biofilm overproduction in a region with endemic MRSA...
  48. ncbi CTX-M-1 extended-spectrum beta-lactamase-producing Proteus mirabilis in Greece
    Paraskevi Karapavlidou
    Department of Microbiology, Hippokration University Hospital, 546 42 Thessaloniki, Greece
    Microb Drug Resist 11:351-4. 2005
    ..The emergence of CTX-M-1- producing P. mirabilis indicates the need for early recognition of such strains to be able to control their spread in our hospital and community environment...
  49. doi In vitro activity of tigecycline against 2423 clinical isolates and comparison of the available interpretation breakpoints
    Joseph Papaparaskevas
    Department of Microbiology, National and Kapodistrian University of Athens, Greece
    Diagn Microbiol Infect Dis 66:187-94. 2010
    ..Indications that the available criteria might categorize differently tigecycline susceptibility status in K. pneumoniae and Enterobacter spp. isolates were also detected...
  50. doi Differences in biofilm formation and virulence factors between clinical and fecal enterococcal isolates of human and animal origin
    Giorgos Tsikrikonis
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    Microb Pathog 52:336-43. 2012
    ..faecalis isolates. Production of gelatinase was associated with the proportion and the degree of biofilm production mainly in animal E. faecalis isolates...
  51. pmc Activity of oxacillin versus that of vancomycin against oxacillin-susceptible mecA-positive Staphylococcus aureus clinical isolates evaluated by population analyses, time-kill assays, and a murine thigh infection model
    Maria Labrou
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    Antimicrob Agents Chemother 56:3388-91. 2012
    ..05) in 8 isolates. The favorable response to dicloxacillin treatment might suggest that antistaphylococcal penicillins could be used against OS-MRSA infections...
  52. pmc Outbreak of infections caused by Enterobacter cloacae producing the integron-associated beta-lactamase IBC-1 in a neonatal intensive care unit of a Greek hospital
    Georgia Kartali
    Department of Microbiology, Hippokration General Hospital, Thessaloniki, Greece
    Antimicrob Agents Chemother 46:1577-80. 2002
    ..cloacae isolates from other wards of the hospital. It seems that this integron-associated gene is capable of dispersing both by clonal spread and by gene dissemination...
  53. doi Emergence of VIM-1 metallo-β-lactamase-producing Escherichia coli in a neonatal intensive care unit
    Maria Papadimitriou
    Department of Microbiology, Aglaia Kyriakou Children s Hospital, Athens, Greece
    Microb Drug Resist 17:105-8. 2011
    ..The appearance of a metallo-β-lactamase-producing E. coli in NICU is worrisome. Further surveys are needed to determine whether such Enterobacteriaceae may also be spreading in other NICUs...
  54. doi Risk factors for carbapenem-resistant Gram-negative bacteremia in intensive care unit patients
    Christina Routsi
    First Department of Critical Care, Medical School, University of Athens, Evangelismos Hospital, 45 47 Ipsilantou Str, 106 76, Athens, Greece
    Intensive Care Med 39:1253-61. 2013
    ..Carbapenem-resistant (CR) Gram-negative pathogens have increased substantially. This study was performed to identify the risk factors for development of CR Gram-negative bacteremia (GNB) in intensive care unit (ICU) patients...
  55. pmc Comparative evaluation of conventional and real-time PCR assays for detecting Bacteroides fragilis in clinical samples
    Joseph Papaparaskevas
    Department of Microbiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
    J Clin Microbiol 51:1593-5. 2013
    ..Altering the gold standard from "positive culture" to "positive culture or both PCR assays positive" resulted in sensitivities of 91.7% and 100%, respectively, and in specificities of 100% and 98.6%, respectively...
  56. doi Moxifloxacin resistance is prevalent among Bacteroides and Prevotella species in Greece
    Joseph Papaparaskevas
    Department of Microbiology, Medical School, University of Athens, 11527 Athens, Greece
    J Antimicrob Chemother 62:137-41. 2008
    ..However, current European data regarding its activity against anaerobic pathogens are limited. In order to evaluate its potency, we comparatively studied the activity of moxifloxacin against recently isolated Gram-negative anaerobes...
  57. pmc VIM-12, a novel plasmid-mediated metallo-beta-lactamase from Klebsiella pneumoniae that resembles a VIM-1/VIM-2 hybrid
    Spyros Pournaras
    Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece
    Antimicrob Agents Chemother 49:5153-6. 2005
    ..The bla(VIM-12)-associated 59-base element was identical to that described in bla(VIM-2) alleles...
  58. pmc Administration of a triple versus a standard double antimicrobial regimen for human brucellosis more efficiently eliminates bacterial DNA load
    Georgia Vrioni
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    Antimicrob Agents Chemother 58:7541-4. 2014
    ..026). The doxycycline-streptomycin-rifampin regimen eliminates Brucella DNA more efficiently than doxycycline-streptomycin, which may result in superior long-term clearance of Brucella. ..
  59. pmc Growth retardation, reduced invasiveness, and impaired colistin-mediated cell death associated with colistin resistance development in Acinetobacter baumannii
    Spyros Pournaras
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    Antimicrob Agents Chemother 58:828-32. 2014
    ..These observations indicate considerably lower invasiveness of A. baumannii clinical isolates following the development of colistin resistance. ..
  60. doi Inflammatory bowel disease exacerbation associated with Epstein-Barr virus infection
    Evangelia Dimitroulia
    Unit of Virology, Department of Microbiology, Medical School, University of Athens, Athens, Greece
    Dis Colon Rectum 56:322-7. 2013
    ..Epstein-Barr virus infection is associated with inflammatory bowel disease, but its role as a pathogenetic or exacerbating factor remains unclear...
  61. doi Two cases of severe sepsis caused by Bacillus pumilus in neonatal infants
    Maria Kimouli
    Department of Microbiology, Saint Panteleimon General Hospital, Nicea, Greece
    J Med Microbiol 61:596-9. 2012
    ..Both infants were successfully treated with vancomycin. This report reveals the potential role of B. pumilus as a bloodstream pathogen during infancy...
  62. doi Prevalence of Trichomonas vaginalis infection in women attending a major gynaecological hospital in Greece: a cross-sectional study
    Evangelia Theophano Piperaki
    Department of Microbiology, Medical School, University of Athens, 11527 Athens, Greece
    J Clin Pathol 63:249-53. 2010
    ..The prevalence of Trichomonas vaginalis is not accurately estimated, since it is not a reportable disease...
  63. doi In vitro bactericidal activity of human beta-defensin 2 against nosocomial strains
    John G Routsias
    Department of Microbiology, School of Medicine, National and Kapodistrian University of Athens, 75 M Asias St, 11527 Athens, Greece
    Peptides 31:1654-60. 2010
    ..These observations give indications that the natural hBD-2 has a potential therapeutic role against bacterial pathogens and particularly against those exhibiting MDR phenotypes...
  64. pmc Chlamydia trachomatis serovar distribution and Neisseria gonorrhoeae coinfection in male patients with urethritis in Greece
    Helen Papadogeorgakis
    Department of Microbiology, Andreas Sygros Hospital for Skin and Venereal Diseases, Athens, Greece
    J Clin Microbiol 48:2231-4. 2010
    ..Gonococcal coinfection was frequent (30%) and was associated with genovariant Ja (75%, P = 0.008)...
  65. doi Oseltamivir-resistant influenza A(H1N1) 2009 virus in Greece during the post-pandemic 2010-2011 season
    Afroditi Kourti
    Virology Unit, Department of Microbiology, Medical School, University of Athens, 11527 Athens, Greece
    Int J Antimicrob Agents 40:72-4. 2012
    ..In both cases, patients were discharged in good condition despite development of resistance to antiviral treatment...
  66. pmc Escherichia hermannii as the sole isolate from a patient with purulent conjunctivitis
    Aggeliki Poulou
    Department of Microbiology, Medical School, University of Athens, 11527 Athens, Greece
    J Clin Microbiol 46:3848-9. 2008
    ..This is the first report of E. hermannii isolated as the sole pathogen from an infected site without prior antibiotic exposure, confirming the pathogenic potential of the microorganism...
  67. ncbi Frequent detection of cytomegalovirus in the intestine of patients with inflammatory bowel disease
    Evangelia Dimitroulia
    Unit of Virology, Department of Microbiology, Medical School, University of Athens, Athens, Greece
    Inflamm Bowel Dis 12:879-84. 2006
    ....
  68. doi Characterization of Enterobius vermicularis in a human population, employing a molecular-based method from adhesive tape samples
    Evangelia Theophano Piperaki
    Department of Microbiology, Medical School, National University of Athens, Mikras Asias 75, Athens 115 27, Greece
    Mol Cell Probes 25:121-5. 2011
    ..All sequences clustered within the type previously characterized (type B), only reported to date from captive chimpanzees. To the best of our knowledge, this is the first study of E. vermicularis genotypes from a human population...
  69. doi Estimation of seroprevalence of the pandemic H1N1 2009 influenza virus using a novel virus-free ELISA assay for the detection of specific antibodies
    Maria D Mavrouli
    Department of Microbiology, Medical School, University of Athens, Athens, Greece
    Viral Immunol 24:221-6. 2011
    ..The method could be also indicative for the discrimination of immune persons from those susceptible to infection with the pandemic H1N1 strain, as well as for the establishment of effective vaccination programs...
  70. ncbi Adult T-cell leukemia/lymphoma (ATLL): report of two fully documented Hellenic patients
    Styliani I Kokoris
    Haematology Section, 1st Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laikon General Hospital of Athens, Greece
    Leuk Lymphoma 45:715-21. 2004
    ..In conclusion, the two aforementioned patients are the first fully documented ATLL patients described in Greece. Investigation for HTLV-I antibodies should be mandatory in all patients with T-cell lymphoproliferative disorders...
  71. ncbi Transplacental infection of Coxsackievirus B3 pathological findings in the fetus
    Anastasia Konstantinidou
    Department of Pathology, Medical School, National Kapodistrian University of Athens, Athens, Greece
    J Med Virol 79:754-7. 2007
    ....
  72. doi Treatment of viral conjunctivitis with antiviral drugs
    Chrysanthi L Skevaki
    Department of Microbiology, School of Medicine, University of Athens, Athens, Greece
    Drugs 71:331-47. 2011
    ..Caution should be exercised when coadministering other pharmacological agents, such as corticosteroids, because of emerging adverse effects...
  73. doi The challenges of antimicrobial drug resistance in Greece
    Spiros Miyakis
    Infectious Diseases Clinic, Third Department of Medicine, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece
    Clin Infect Dis 53:177-84. 2011
    ..Awareness of resistance patterns and organisms prevailing locally by reporting laboratories and treating physicians is important...
  74. pmc CTX-M-type beta-lactamases affect community Escherichia coli treatment, Greece
    Spyros Pournaras
    Emerg Infect Dis 10:1163-4. 2004
  75. pmc Novel variant (bla(VIM-4)) of the metallo-beta-lactamase gene bla(VIM-1) in a clinical strain of Pseudomonas aeruginosa
    Spyros Pournaras
    Department of Medical Microbiology, University of Thessaly, Larissa, Greece
    Antimicrob Agents Chemother 46:4026-8. 2002
    ..This is the first detection of a VIM-1 variant after its appearance in Italy...
  76. ncbi Persistence of a clone of glycopeptide-resistant Enterococcus faecalis among patients in an intensive care unit of a Greek hospital
    Spyros Pournaras
    Department of Medical Microbiology, University of Thessalia, Larissa
    J Antimicrob Chemother 53:109-12. 2004
    ..To investigate an outbreak of glycopeptide-resistant Enterococcus faecalis (GREF) in the intensive care unit (ICU) of 'G. Gennimatas' General Hospital, Athens, Greece...
  77. ncbi Emergence of carbapenem-resistant Enterobacter cloacae carrying VIM-4 metallo-beta-lactamase and SHV-2a extended-spectrum beta-lactamase in a conjugative plasmid
    Alexandros Ikonomidis
    Department of Medical Microbiology, University of Thessalia, 412 22 Larissa, Greece
    Microb Drug Resist 13:221-6. 2007
    ..It suggests also that different VIM-type gene cassettes have been incorporated in a common integron structure, which seems indigenous of Gram-negative pathogens in our region...
  78. pmc First occurrence of an Escherichia coli clinical isolate producing the VIM-1/VIM-2 hybrid metallo-beta-lactamase VIM-12
    Alexandros Ikonomidis
    Antimicrob Agents Chemother 51:3038-9. 2007
  79. ncbi Detection of a novel variant bla(CTX-M-3) extended spectrum beta-lactamase gene in a community-acquired Escherichia coli isolate
    Spyros Pournaras
    Department of Medical Microbiology, University of Thessalia, Mezourlo, Larissa, Greece
    Scand J Infect Dis 38:213-6. 2006
    ..The bla(CTX-M-3) variant was located downstream of an ISEcp1B element. The emergence of this new derivative indicates further evolution of the worldwide-distributed bla(CTX-M-3) gene...
  80. ncbi Carriage of OXA-58 but not of OXA-51 beta-lactamase gene correlates with carbapenem resistance in Acinetobacter baumannii
    Athanassios Tsakris
    J Antimicrob Chemother 58:1097-9. 2006
  81. ncbi Frequency and predictors of colonization of the respiratory tract by VIM-2-producing Pseudomonas aeruginosa in patients of a newly established intensive care unit
    Maria Horianopoulou
    Intensive Care Unit, Sismanoglio General Hospital, Athens, Greece
    J Med Microbiol 55:1435-9. 2006
    ..Use of beta-lactams, including carbapenems, was associated with subsequent colonization of the respiratory tract with MBL-positive P. aeruginosa...
  82. ncbi Characterization of clinical isolates of Pseudomonas aeruginosa heterogeneously resistant to carbapenems
    Spyros Pournaras
    Department of Medical Microbiology, University of Thessalia, Mezourlo, Larissa, Greece
    J Med Microbiol 56:66-70. 2007
    ..These findings may be indicative that the use of carbapenems can lead to selection of P. aeruginosa resistant subpopulations that subsequently cause infections and result in treatment failure...
  83. ncbi Persistence of rRNA operon mutated copies and rapid re-emergence of linezolid resistance in Staphylococcus aureus
    Athanassios Tsakris
    Division of Infectious Diseases, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02115, USA
    J Antimicrob Chemother 60:649-51. 2007
    ....
  84. doi Piperacillin/tazobactam-heteroresistant Pseudomonas aeruginosa from urinary infection, successfully treated by piperacillin/tazobactam
    Spyros Pournaras
    J Antimicrob Chemother 61:757-8. 2008
  85. doi Multidrug-resistant Klebsiella pneumoniae mediastinitis safely and effectively treated with prolonged administration of tigecycline
    Penelope Evagelopoulou
    Clin Infect Dis 46:1932-3. 2008
  86. pmc Emergence of vancomycin-intermediate Staphylococcus aureus and S. sciuri, Greece
    Athanassios Tsakris
    Emerg Infect Dis 8:536-7. 2002
  87. ncbi Spread of an unusual penicillin- and imipenem-resistant but ampicillin-susceptible phenotype among Enterococcus faecalis clinical isolates
    Evgenia Metzidie
    J Antimicrob Chemother 57:158-60. 2006
  88. ncbi CTX-M enzymes are the most common extended-spectrum beta-lactamases among Escherichia coli in a tertiary Greek hospital
    Spyros Pournaras
    J Antimicrob Chemother 54:574-5. 2004
  89. doi Cross-transmission of multidrug-resistant Acinetobacter baumannii clonal strains causing episodes of sepsis in a trauma intensive care unit
    Antonios Markogiannakis
    Department of Basic Sciences, School of Health Sciences, University of Athens, Greece
    Infect Control Hosp Epidemiol 29:410-7. 2008
    ..To investigate the mode of transmission of imipenem-resistant Acinetobacter baumannii strains causing episodes of sepsis...