Roberta A Gottlieb

Summary

Publications

  1. pmc Cardioprotection through autophagy: ready for clinical trial?
    Roberta A Gottlieb
    Radical Therapeutix, Inc, Solana Beach, CA, USA
    Autophagy 7:434-5. 2011
  2. pmc Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts
    Jon Sin
    a The Cedars Sinai Heart Institute and the Barbra Streisand Women s Heart Center Cedars Sinai Medical Center, Los Angeles, CA, USA
    Autophagy 12:369-80. 2016
  3. doi Measuring cardiac autophagic flux in vitro and in vivo
    Michael A Gurney
    Donald P Shiley BioScience Center, San Diego State University, 5500 Campanile Dr, San Diego, CA, 92182 4650, USA
    Methods Mol Biol 1219:187-97. 2015
  4. pmc This old heart: Cardiac aging and autophagy
    Phyllis Jean Linton
    Donald P Shiley BioScience Center, San Diego State University, San Diego, CA, USA
    J Mol Cell Cardiol 83:44-54. 2015
  5. pmc Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
    Raquel S Carreira
    BioScience Center, San Diego State University, San Diego, CA, USA
    Autophagy 6:462-72. 2010
  6. pmc Impaired mitophagy at the heart of injury
    Roberta A Gottlieb
    Donald P Shiley BioScience Center, San Diego State University, San Diego, CA, USA
    Autophagy 7:1573-4. 2011
  7. pmc Autophagy: an affair of the heart
    Roberta A Gottlieb
    Donald P Shiley BioScience Center, San Diego State University, San Diego, CA, USA
    Heart Fail Rev 18:575-84. 2013
  8. pmc Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice
    Chengqun Huang
    San Diego State University, BioScience Center and Department of Biology, CA, USA
    Circulation 121:675-83. 2010

Collaborators

  • Robert M Mentzer
  • Asa B Gustafsson
  • Chengqun Huang
  • Jon Sin
  • Phyllis Jean Linton
  • Allen M Andres
  • Michael A Gurney
  • Jennifer M Ramil
  • Raquel S Carreira
  • Youngil Lee
  • Aleksandr Stotland
  • Brandon J Kim
  • Thomas Weston
  • Yoshimi Hiraumi
  • Kelly S Doran
  • David J R Taylor
  • David Sengstock
  • Nandini Ravindran
  • Michael Gurney
  • Shivaji Rikka
  • Mariam Ghochani
  • Lucy Kim
  • Mark A Sussman
  • Patricia A Thistlethwaite
  • Natalie A Gude
  • Xiaoxue Zhang

Detail Information

Publications8

  1. pmc Cardioprotection through autophagy: ready for clinical trial?
    Roberta A Gottlieb
    Radical Therapeutix, Inc, Solana Beach, CA, USA
    Autophagy 7:434-5. 2011
    ..Since 2005 several studies have implicated autophagy as a target for cardioprotection...
  2. pmc Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts
    Jon Sin
    a The Cedars Sinai Heart Institute and the Barbra Streisand Women s Heart Center Cedars Sinai Medical Center, Los Angeles, CA, USA
    Autophagy 12:369-80. 2016
    ..Together these data highlight the integral role of autophagy and mitophagy in myogenic differentiation. ..
  3. doi Measuring cardiac autophagic flux in vitro and in vivo
    Michael A Gurney
    Donald P Shiley BioScience Center, San Diego State University, 5500 Campanile Dr, San Diego, CA, 92182 4650, USA
    Methods Mol Biol 1219:187-97. 2015
    ..Here, we describe a method for determining autophagic flux in vitro and in vivo using the autophagosomal/lysosomal fusion inhibitors chloroquine or bafilomycin A1 and then probing for the autophagosomal marker LC3-II via Western Blot...
  4. pmc This old heart: Cardiac aging and autophagy
    Phyllis Jean Linton
    Donald P Shiley BioScience Center, San Diego State University, San Diego, CA, USA
    J Mol Cell Cardiol 83:44-54. 2015
    ..This article is part of a Special Issue entitled CV Aging. ..
  5. pmc Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
    Raquel S Carreira
    BioScience Center, San Diego State University, San Diego, CA, USA
    Autophagy 6:462-72. 2010
    ..Starvation-induced autophagy regulated by CypD and the MPT may represent a homeostatic mechanism for cellular and mitochondrial quality control...
  6. pmc Impaired mitophagy at the heart of injury
    Roberta A Gottlieb
    Donald P Shiley BioScience Center, San Diego State University, San Diego, CA, USA
    Autophagy 7:1573-4. 2011
    ..The field is in need of methods to monitor mitochondrial turnover in vivo to support the development of new therapies targeting mitochondrial turnover...
  7. pmc Autophagy: an affair of the heart
    Roberta A Gottlieb
    Donald P Shiley BioScience Center, San Diego State University, San Diego, CA, USA
    Heart Fail Rev 18:575-84. 2013
    ..Contradictory findings are reconciled in light of recent developments. The preponderance of evidence favors a beneficial role for autophagy in the heart under most conditions. ..
  8. pmc Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice
    Chengqun Huang
    San Diego State University, BioScience Center and Department of Biology, CA, USA
    Circulation 121:675-83. 2010
    ..To date, very little is known about the mechanism of this late-onset cardiotoxicity...