Xenia Gonda

Summary

Publications

  1. doi request reprint Towards a genetically validated new affective temperament scale: a delineation of the temperament phenotype of 5-HTTLPR using the TEMPS-A
    X Gonda
    Department of Pharmacology and Pharmacotherapy, Semmelweis University, Faculty of Medicine, Kutvolgyi Clinical Centre, 1089 Budapest Nagyvarad ter 4, Hungary
    J Affect Disord 112:19-29. 2009
  2. doi request reprint Association of depressive phenotype with affective family history is mediated by affective temperaments
    Judit Lazary
    Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Budapest, Hungary
    Psychiatry Res 168:145-52. 2009
  3. pmc How possible is the development of an operational psychometric method to assess the presence of the 5-HTTLPR s allele? Equivocal preliminary findings
    Xenia Gonda
    Department of Pharmacodynamics, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    Ann Gen Psychiatry 9:21. 2010
  4. pmc Antidepressant-resistant depression and antidepressant-associated suicidal behaviour: the role of underlying bipolarity
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Kutvolgyi ut 4, 1125 Budapest, Hungary
    Depress Res Treat 2011:906462. 2011
  5. pmc Prediction and prevention of suicide in patients with unipolar depression and anxiety
    Xenia Gonda
    Department of Psychiatry, No III, National Institute for Psychiatry and Neurology, Budapest, Hungary
    Ann Gen Psychiatry 6:23. 2007
  6. pmc Suicide in Hungary-epidemiological and clinical perspectives
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Faculty of Medicine, Semmelweis University, Budapest, Hungary
    Ann Gen Psychiatry 12:21. 2013
  7. doi request reprint Suicidal behavior in bipolar disorder: epidemiology, characteristics and major risk factors
    Xenia Gonda
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Kutvolgyi ut 4, 1125 Budapest, Hungary
    J Affect Disord 143:16-26. 2012
  8. doi request reprint Star-crossed? The association of the 5-HTTLPR s allele with season of birth in a healthy female population, and possible consequences for temperament, depression and suicide
    Xenia Gonda
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
    J Affect Disord 143:75-83. 2012
  9. ncbi request reprint Associations between season of birth and suicide: a brief review
    Jon Honerod Antonsen
    NAF garden family practice, Brumunddal, Norway
    Neuropsychopharmacol Hung 14:177-87. 2012
  10. ncbi request reprint Basic pharmacology of NMDA receptors
    Xenia Gonda
    Department of Clinical and Theoretical Mental Health, Semmelweis University, Budapest, Hungary
    Curr Pharm Des 18:1558-67. 2012

Detail Information

Publications81

  1. doi request reprint Towards a genetically validated new affective temperament scale: a delineation of the temperament phenotype of 5-HTTLPR using the TEMPS-A
    X Gonda
    Department of Pharmacology and Pharmacotherapy, Semmelweis University, Faculty of Medicine, Kutvolgyi Clinical Centre, 1089 Budapest Nagyvarad ter 4, Hungary
    J Affect Disord 112:19-29. 2009
    ..The aim of our study was to investigate the association of affective temperament subscales and individual items with the s allele of the 5-HTTLPR...
  2. doi request reprint Association of depressive phenotype with affective family history is mediated by affective temperaments
    Judit Lazary
    Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Budapest, Hungary
    Psychiatry Res 168:145-52. 2009
    ..The probability of having any dominant temperament was more than two-fold in group AFH(1) compared with AFH(0) (OR=2.33). Our results suggest that a crucial part of inherited factors of depression is mediated by affective temperaments...
  3. pmc How possible is the development of an operational psychometric method to assess the presence of the 5-HTTLPR s allele? Equivocal preliminary findings
    Xenia Gonda
    Department of Pharmacodynamics, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    Ann Gen Psychiatry 9:21. 2010
    ..The aim of the current study was to develop a psychometric tool that could at least partially substitute for laboratory testing and could predict the presence of the s allele...
  4. pmc Antidepressant-resistant depression and antidepressant-associated suicidal behaviour: the role of underlying bipolarity
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Kutvolgyi ut 4, 1125 Budapest, Hungary
    Depress Res Treat 2011:906462. 2011
    ....
  5. pmc Prediction and prevention of suicide in patients with unipolar depression and anxiety
    Xenia Gonda
    Department of Psychiatry, No III, National Institute for Psychiatry and Neurology, Budapest, Hungary
    Ann Gen Psychiatry 6:23. 2007
    ..The proper use of antidepressants, after a careful diagnostic evaluation, is important and recent studies suggest that successful acute and long-term antidepressant pharmacotherapy reduces suicide morbidity and mortality...
  6. pmc Suicide in Hungary-epidemiological and clinical perspectives
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Faculty of Medicine, Semmelweis University, Budapest, Hungary
    Ann Gen Psychiatry 12:21. 2013
    ..Eventually, we discuss the results, the possibilities, and the future tasks of suicide prevention in Hungary. ..
  7. doi request reprint Suicidal behavior in bipolar disorder: epidemiology, characteristics and major risk factors
    Xenia Gonda
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Kutvolgyi ut 4, 1125 Budapest, Hungary
    J Affect Disord 143:16-26. 2012
    ....
  8. doi request reprint Star-crossed? The association of the 5-HTTLPR s allele with season of birth in a healthy female population, and possible consequences for temperament, depression and suicide
    Xenia Gonda
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
    J Affect Disord 143:75-83. 2012
    ..Our aim was to investigate the association of 5-HTTLPR genotype and birth season in a healthy female population...
  9. ncbi request reprint Associations between season of birth and suicide: a brief review
    Jon Honerod Antonsen
    NAF garden family practice, Brumunddal, Norway
    Neuropsychopharmacol Hung 14:177-87. 2012
    ..In our narrative review we summarize and discuss the available literature on the relevance of the most important findings concerning the above fields...
  10. ncbi request reprint Basic pharmacology of NMDA receptors
    Xenia Gonda
    Department of Clinical and Theoretical Mental Health, Semmelweis University, Budapest, Hungary
    Curr Pharm Des 18:1558-67. 2012
    ..Nevertheless, NMDA receptors offer a novel opportunity in the treatment of various neuropsychiatric conditions...
  11. pmc Humor appreciation of captionless cartoons in obsessive-compulsive disorder
    Vasilis P Bozikas
    First Department of Psychiatry, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Ann Gen Psychiatry 10:31. 2011
    ..However, to date, there have been no studies that have explored humor appreciation in OCD. The purpose of the present work was to investigate humor appreciation in a group of patients with OCD...
  12. pmc Class effect of pharmacotherapy in bipolar disorder: fact or misbelief?
    Konstantinos N Fountoulakis
    Third Department of Psychiatry, School of Medicine, Aristotle University of Thessaloniki, Greece
    Ann Gen Psychiatry 10:8. 2011
    ..The present article explores the possible existence of a true 'class effect' for agents available for the treatment of bipolar disorder...
  13. pmc Treatment of psychotic symptoms in bipolar disorder with aripiprazole monotherapy: a meta-analysis
    Konstantinos N Fountoulakis
    Third Department of Psychiatry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Ann Gen Psychiatry 8:27. 2009
    ..We present a systematic review and meta-analysis of the available clinical trials concerning the usefulness of aripiprazole in the treatment of the psychotic symptoms in bipolar disorder...
  14. ncbi request reprint [Characteristics of depression in the elderly]
    Xenia Gonda
    Semmelweis Egyetem, Általános Orvostudományi Kar, Farmakológiai és Farmakoterápiás Intézet
    Psychiatr Hung 24:166-74. 2009
    ....
  15. doi request reprint Interaction of 5-HTTLPR genotype and unipolar major depression in the emergence of aggressive/hostile traits
    Xenia Gonda
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
    J Affect Disord 132:432-7. 2011
    ..Our aim was to investigate the association between 5-HTTLPR and aggressive/hostile traits in depressed patients and controls...
  16. doi request reprint Association of a trait-like bias towards the perception of negative subjective life events with risk of developing premenstrual symptoms
    Xenia Gonda
    Department of Pharmacology and Pharmacotherapy, Semmelweis University, Faculty of Medicine, Nagyvarad ter 4, 1089 Budapest, Hungary
    Prog Neuropsychopharmacol Biol Psychiatry 34:500-5. 2010
    ....
  17. doi request reprint From putative genes to temperament and culture: cultural characteristics of the distribution of dominant affective temperaments in national studies
    Xenia Gonda
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
    J Affect Disord 131:45-51. 2011
    ..The aim of the present study was to investigate the characteristics of distribution of dominant affective temperaments in different national studies of general non-clinical population...
  18. doi request reprint Association of the s allele of the 5-HTTLPR with neuroticism-related traits and temperaments in a psychiatrically healthy population
    Xenia Gonda
    Dept of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Centre, Semmelweis University, Kutvolgyi ut 4, 1125, Budapest, Hungary
    Eur Arch Psychiatry Clin Neurosci 259:106-13. 2009
    ..The aim of our study was to investigate the association of the 5-HTTLPR polymorphism with several smaller, distinct and better characterisable phenomena related to the neuroticism trait...
  19. doi request reprint The possible contributory role of the S allele of 5-HTTLPR in the emergence of suicidality
    Xenia Gonda
    Department of Pharmacodynamics, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    J Psychopharmacol 25:857-66. 2011
    ..This study aimed to integrate findings concerning possible endophenotypes modulating between genetic factors and manifested suicidal behaviour...
  20. doi request reprint Patterns of mood changes throughout the reproductive cycle in healthy women without premenstrual dysphoric disorders
    X Gonda
    Department of Pharmacology and Pharmacotherapy, Semmelweis University, Faculty of Medicine, Nagyvarad ter 4, 1089 Budapest, Hungary
    Prog Neuropsychopharmacol Biol Psychiatry 32:1782-8. 2008
    ..The aim of our study was to investigate the fluctuation of psychological symptoms throughout the female reproductive cycle in healthy, non-PMDD (premenstrual dysphoric disorder) women...
  21. doi request reprint [The serotonin transporter gene and personality: association of the 5-HTTLPR s allele, anxiety, depression and affective temperaments]
    Xenia Gonda
    Semmelweis Egyetem, Altalános Orvostudományi Kar Farmakológiai és Farmakoterápiás Intézet Budapest, Hungary
    Orv Hetil 149:1569-73. 2008
    ....
  22. ncbi request reprint Mood parameters and severe physical symptoms of the female reproductive cycle
    Xenia Gonda
    Department of Pharmacology and Pharmacotherapy, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    Neuropsychopharmacol Hung 10:91-6. 2008
    ..The aim of our study was to investigate the fluctuation of psychological and physical symptoms throughout the female reproductive cycle in healthy, non-PMDD women...
  23. ncbi request reprint [Affective temperaments: psychometric properties of the Hungarian TEMPS-A]
    Sándorter Rózsa
    Eotvos Lorand Tudomanyegyetem, Pedagogiai és Pszichologiai Intezet, Budapest, Hungary
    Psychiatr Hung 21:147-60. 2006
    ..Based on the results obtained with the Hungarian normative sample, the TEMPS-A is a reliable and valid instrument in personality psychology, and further refinement on clinical samples opens new and interesting research avenues...
  24. doi request reprint Affective temperaments, as measured by TEMPS-A, among nonviolent suicide attempters
    Annamaria Rihmer
    Department of Psychiatry and Psychotherapy, Semmelweis University, Balassa u 6 1086 Budapest, Hungary
    J Affect Disord 116:18-22. 2009
    ..The aim of this study was to investigate the role of affective temperaments in suicidal behavior...
  25. ncbi request reprint The 5HTTLPR polymorphism of the serotonin transporter gene is associated with affective temperaments as measured by TEMPS-A
    Xenia Gonda
    Laboratory of Neurochemistry and Experimental Medicine, National Institute for Psychiatry and Neurology, Budapest, Hungary
    J Affect Disord 91:125-31. 2006
    ....
  26. ncbi request reprint [The role of childhood abuse in adult suicidal behaviour]
    Annamaria Rihmer
    Semmelweis Egyetem, Pszichiatriai es Pszichoterapias Klinika, Budapest, Hungary
    Neuropsychopharmacol Hung 11:237-46. 2009
    ..However, regardless of gender, it was significantly more severe (p<0.01) among those who were victims of both physical and sexual childhood abuse...
  27. doi request reprint Affective temperament, history of suicide attempt and family history of suicide in general practice patients
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Budapest, Hungary
    J Affect Disord 149:350-4. 2013
    ..In the present study our aim was to investigate the association between affective temperaments, personal history of suicide attempts and family history of completed suicide in primary practice patients...
  28. doi request reprint Peripheral vascular endothelial growth factor level is associated with antidepressant treatment response: results of a preliminary study
    Zsuzsa Halmai
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    J Affect Disord 144:269-73. 2013
    ..In this study we were interested in investigating a possible association between VEGF levels and treatment response in patients with a current episode of major depression (MDE)...
  29. doi request reprint Genetic variants in the catechol-o-methyltransferase gene are associated with impulsivity and executive function: relevance for major depression
    Dorottya Pap
    Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 159:928-40. 2012
    ..These findings emphasise that modeling of disease pathways at phenotypic level are valuable for identifying genetic risk factors...
  30. ncbi request reprint A new clinical evidence-based gene-environment interaction model of depression
    Gyorgy Bagdy
    Department of Pharmacodynamics, Semmelweis University, 1089 Budapest, Hungary
    Neuropsychopharmacol Hung 14:213-20. 2012
    ..In this review we introduce a new model including environmental factors, genes, trait and temperament markers based on human genetic studies...
  31. doi request reprint Seasonality and winter-type seasonal depression are associated with the rs731779 polymorphism of the serotonin-2A receptor gene
    Eszter Molnar
    Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary
    Eur Neuropsychopharmacol 20:655-62. 2010
    ..The fact that the above polymorphism showed association not only with clinical SAD but also seasonality symptoms in a general population provides evidence for the spectrum nature of this connection...
  32. doi request reprint Promoter variants of the cannabinoid receptor 1 gene (CNR1) in interaction with 5-HTTLPR affect the anxious phenotype
    Judit Lazary
    Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 150:1118-27. 2009
    ..In conclusion, genetically determined serotonergic and endocannabinoid dysfunctions could lead to a vulnerability causing anxiety disorders and possibly depression...
  33. ncbi request reprint Cigarette smoking and suicide attempts in psychiatric outpatients in Hungary
    Zoltan Rihmer
    Psychiatry No 3, National Institute for Psychiatry and Neurology, Huvosvolgyi ut 116, Budapest, 1021 Hungary
    Neuropsychopharmacol Hung 9:63-7. 2007
    ..Epidemiological and clinical studies have found a significant association between smoking and suicidal behaviour...
  34. ncbi request reprint [Screening of depression in primary care in Hungary and its importance in suicide prevention]
    Zoltan Rihmer
    Semmelweis Egyetem AOK, Klinikai es Kutatasi Mentalhigienes Osztaly, Budapest, Hungary
    Psychiatr Hung 27:224-32. 2012
    ..Family history of completed suicide as a clinical marker could improve suicide prevention through the more effective management of MDE in primary care...
  35. ncbi request reprint The relationship between the big five personality dimensions and acute psychopathology: mediating and moderating effects of coping strategies
    Zsuzsanna Mirnics
    Institute of Psychology, Károli Gáspár University of the Reformed Church, 1037 Bp Bécsi út 324, Budapest, Hungary
    Psychiatr Danub 25:379-88. 2013
    ..The aim of the present study was to investigate direct and indirect associations between the Big Five personality traits, coping styles, and psychopathological variables...
  36. doi request reprint Associations between depression severity and purinergic receptor P2RX7 gene polymorphisms
    Zsuzsa Halmai
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
    J Affect Disord 150:104-9. 2013
    ..In the current study the genetic effects of rs2230912 (Gln460Arg) and rs1653625 (located in the 3' untranslated region of the P2RX7 gene) were explored in mood disorders...
  37. doi request reprint New evidence for the association of the serotonin transporter gene (SLC6A4) haplotypes, threatening life events, and depressive phenotype
    Judit Lazary
    Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary
    Biol Psychiatry 64:498-504. 2008
    ..To clarify this question, we analyzed the interaction between the serotonin transporter gene (SLC6A4) and threatening life events (TLE) on Zung Self-Rating Depression Score (ZSDS)...
  38. doi request reprint Significant association between the C(-1019)G functional polymorphism of the HTR1A gene and impulsivity
    Anita Benko
    Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 153:592-9. 2010
    ..002), and for the BIS total score (P = 0.008) but not for the Nonplanning Impulsiveness (P = 0.520) subscale of the BIS-11. Our results suggest the involvement of the HTR(1A) in the continuum phenotype of impulsivity...
  39. ncbi request reprint A study of affective temperaments in Hungary: internal consistency and concurrent validity of the TEMPS-A against the TCI and NEO-PI-R
    Sandor Rozsa
    Department of Personality and Health Psychology, Lorand Eotvos University, Budapest, Hungary
    J Affect Disord 106:45-53. 2008
    ..We were particularly interested in concurrent validation against the TCI and the NEO-PI-R, the most important of the new personality instruments...
  40. ncbi request reprint [Relationship between serotonin transporter gene 5HTTLPR polymorphism and the symptoms of neuroticism in a healthy population]
    Xenia Gonda
    Orszagos Pszichiatriai es Neurologiai Intezet, Neurokémiai és Neuropszichofarmakológiai Laboratórium, Budapest, Hungary
    Psychiatr Hung 21:379-85. 2006
    ..Less attention has been paid to the relationship of this polymorphism with a tendency for depression and anxiety within a healthy population...
  41. ncbi request reprint Cultural differences in the development and characteristics of depression
    Gabriella Juhasz
    Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary
    Neuropsychopharmacol Hung 14:259-65. 2012
    ..In the present paper we describe the most consistently replicated findings concerning the most important cross-national differences in the rates and characteristics of depression with a short comment on possible background factors...
  42. doi request reprint Association between affective temperaments and season of birth in a general student population
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University Kutvolgyi ut 4, 1125 Budapest, Hungary
    J Affect Disord 132:64-70. 2011
    ..The aim of our present study was to investigate the association between affective temperaments and season of birth in a nonclinical sample...
  43. doi request reprint Association of the STin2 polymorphism of the serotonin transporter gene with a neurocognitive endophenotype in major depressive disorder
    Andrea Sarosi
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Kutvolgyi ut 4, 1125 Budapest, Hungary
    Prog Neuropsychopharmacol Biol Psychiatry 32:1667-72. 2008
    ..The aim of our study was to investigate the association of STin2 polymorphism and cognitive dysfunction in major depression...
  44. pmc Interleukin-6 promoter polymorphism interacts with pain and life stress influencing depression phenotypes
    David Kovacs
    Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Nagyvarad ter 4, Budapest, 1089, Hungary
    J Neural Transm (Vienna) 123:541-8. 2016
    ..Thus, IL-6 and other cytokines may be more relevant in the development of somatic symptoms compared to affective signs of depression, delineating a specific genotype-phenotype relationship in this heterogeneous disorder. ..
  45. doi request reprint Gender differences in antidepressant use-related seasonality change in suicide mortality in Hungary, 1998-2006
    Beata Sebestyen
    National Center for Healthcare Audit and Inspection, Budapest, Hungary
    World J Biol Psychiatry 11:579-85. 2010
    ..The aim of the present study was to analyse the relationship between increasing antidepressant utilization and national suicide rate of Hungary between 1998 and 2006, with particular regard to seasonal patterns and gender differences...
  46. ncbi request reprint [Epidemiology, characteristics and risk factors of suicidal behaviour in bipolar disorder]
    Xenia Gonda
    Semmelweis Egyetem, Klinikai es Kutatasi Mentalhigienes Osztaly, Kútvölgyi Klinikai Tömb, Budapest, Hungary
    Psychiatr Hung 27:103-14. 2012
    ....
  47. doi request reprint The possible protective role of personality dimensions against premenstrual syndrome
    Tamas Telek
    Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvarad ter 4, 1089 Budapest, Hungary
    Psychiatry Res 179:81-5. 2010
    ....
  48. ncbi request reprint Association analysis of 5-HTTLPR variants, 5-HT2a receptor gene 102T/C polymorphism and migraine
    Gabriella Juhasz
    Laboratory of Neurochemistry and Experimental Medicine, and Department of Vascular Neurology, Faculty of Medicine, Semmelweis University, National Institute of Psychiatry and Neurology, Budapest, Hungary
    J Neurogenet 17:231-40. 2003
    ..In conclusion, our results support that the genetic susceptibility of migraine may be associated with a locus at or near the 5-HT transporter gene...
  49. pmc Hyperthymic affective temperament and hypertension are independent determinants of serum brain-derived neurotrophic factor level
    Janos Nemcsik
    Department of Family Medicine, Semmelweis University Budapest, Budapest, Hungary Health Service of Zugló ZESZ, Budapest, Hungary
    Ann Gen Psychiatry 15:17. 2016
    ..Here, we measured serum BDNF (seBDNF) level in hypertensive patients (HT) and healthy controls (CONT) and its relation to affective temperaments, depression and anxiety scales, and arterial stiffness parameters...
  50. doi request reprint Effects of IL1B single nucleotide polymorphisms on depressive and anxiety symptoms are determined by severity and type of life stress
    David Kovacs
    Department of Pharmacodynamics, Semmelweis University, Nagyvarad ter 4, Budapest, Hungary MTA SE Neuropsychopharmacology and Neurochemistry Research Group, Hungarian Academy of Sciences, Nagyvarad ter 4, Budapest, Hungary Electronic address
    Brain Behav Immun 56:96-104. 2016
    ..Therefore our results suggest that it is advisable to include environmental factors in genetic association studies when examining the effect of the IL1B gene. ..
  51. ncbi request reprint Prevention of depression-related suicides in primary care
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Semmelweis University, Budapest, Hungary
    Psychiatr Hung 27:72-81. 2012
    ....
  52. ncbi request reprint Development of Depression Profile: a new psychometric instrument to selectively evaluate depressive symptoms based on the neurocircuitry theory
    Gabor Faludi
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
    Neuropsychopharmacol Hung 12:337-45. 2010
    ..The aim of our study was to investigate the psychometric characteristics of Depression Profile...
  53. ncbi request reprint [Etiopathology and therapy of seasonal affective disorder]
    Eszter Molnar
    Gyógyszerhatástani Intézet, Semmelweis Egyetem, Gyógyszerésztudományi Kar, Budapest, Hungary
    Neuropsychopharmacol Hung 12:483-94. 2010
    ..In practice the most effective treatment for SAD is the combination of light therapy, antidepressants and psychotherapy...
  54. doi request reprint Family history of suicide: a clinical marker for major depression in primary care practice?
    Peter Torzsa
    Department of Family Medicine, Kutvolgyi Clinical Center, Semmelweis University, Faculty of Medicine, Kutvolgyi ut 4, 1125 Budapest, Hungary
    J Affect Disord 117:202-4. 2009
    ..The aim of this study was to investigate the family history of suicide among primary care patients with or without current major depressive episode (MDE)...
  55. pmc Variability in the effect of 5-HTTLPR on depression in a large European population: the role of age, symptom profile, type and intensity of life stressors
    Gabriella Juhasz
    Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Budapest, Hungary MTA SE Neuropsychopharmacology and Neurochemistry Research Group, Hungarian Academy of Sciences, Semmelweis University, Budapest, Hungary Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, United Kingdom, and Manchester Academic Health Sciences Centre, Manchester, United Kingdom
    PLoS ONE 10:e0116316. 2015
    ..Although 5-HTTLPR has been shown to influence the risk of life stress-induced depression in the majority of studies, others have produced contradictory results, possibly due to weak effects and/or sample heterogeneity...
  56. pmc Brain galanin system genes interact with life stresses in depression-related phenotypes
    Gabriella Juhasz
    Department of Pharmacodynamics, Semmelweis University, 1089, Budapest, Hungary
    Proc Natl Acad Sci U S A 111:E1666-73. 2014
    ..Correcting abnormal galanin function in depression could prove to be a novel target for drug development. The findings further emphasize the importance of modeling environmental interaction in finding new genes for depression. ..
  57. ncbi request reprint Pharmaco- and therapygenetic aspects in the treatment of anxiety disorders beyond the serotonergic system: a brief review
    Gabor Faludi
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, 1125 Budapest, Hungary
    Neuropsychopharmacol Hung 14:221-9. 2012
    ..We discuss the current knowledge on pharmacogenetic/therapygenetic aspects of anxiety disorders beyond the serotonergic system...
  58. doi request reprint Novel approaches to drug-placebo difference calculation: evidence from short-term antidepressant drug-trials
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Faculty of Medicine, Semmelweis University, Budapest, Hungary
    Hum Psychopharmacol 26:307-12. 2011
    ....
  59. ncbi request reprint The importance of depressive mixed states in suicidal behaviour
    Annamaria Rihmer
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Neuropsychopharmacol Hung 10:45-9. 2008
    ..DMX and agitated depression should be considered as bipolar spectrum. These should be taken into consideration in clinical and diagnostic work with affective disorder patients...
  60. ncbi request reprint [Investigation of the association between arsenic levels in drinking water and suicide rate of Hungarian settlements between 2005 and 2011. A preliminary study]
    Zoltan Rihmer
    Semmelweis Egyetem Klinikai es Kutatasi Mentalhigienes Osztaly es Pszichiatriai es Pszichoterapias Klinika, Budapest, Hungary, E mail
    Psychiatr Hung 31:176-81. 2016
    ..Since untreated depression is the most powerful risk factor for suicidal behaviour, we postulated that the consumption of arsenic-contaminated tap drinking-water may also be related to suicide...
  61. ncbi request reprint The role of general practitioners in prevention of depression-related suicides
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Semmelweis University, Budapest, Hungary
    Neuropsychopharmacol Hung 14:245-51. 2012
    ....
  62. doi request reprint Psychiatry should not become hostage to placebo: an alternative interpretation of antidepressant-placebo differences in the treatment response in depression
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    Eur Neuropsychopharmacol 22:782-6. 2012
    ..It is widely believed that in randomized controlled trials of antidepressants the difference between drug and placebo response rates is rather small (around 20%), leading to a common perception that antidepressants have limited efficacy...
  63. ncbi request reprint [Economic recession, unemployment and suicide]
    Timea Duleba
    Semmelweis Egyetem Kutvolgyi Klinikai Tomb, Klinikai es Kutatasi Mentalhigienes Osztaly, Budapest, Hungary
    Neuropsychopharmacol Hung 14:41-50. 2012
    ....
  64. ncbi request reprint [Diagnostic features, epidemiology, and pathophysiology of seasonal affective disorder]
    Eszter Molnar
    Gyógyszerhatástani Intézet, Semmelweis Egyetem, Gyógyszerésztudományi Kar, Budapest, Hungary
    Psychiatr Hung 25:407-16. 2010
    ..Genetic studies focusing on candidate genes involve 5-HTR2A, 5-HTR2C, DRD4, G protein, and clock-related genes...
  65. doi request reprint Psychological side effects of immune therapies: symptoms and pathomechanism
    David Kovacs
    MTA SE Neuropsychopharmacology and Neurochemistry Research Group, Hungarian Academy of Sciences, Budapest, Hungary
    Curr Opin Pharmacol 29:97-103. 2016
    ..Thus future research should develop strategies to identify those MDD patients who could benefit from drugs acting through inflammatory pathways. ..
  66. doi request reprint Personality and cardiovascular risk: association between hypertension and affective temperaments-a cross-sectional observational study in primary care settings
    Ajandek Eory
    Department of Family Medicine Semmelweis University, Budapest, Hungary
    Eur J Gen Pract 20:247-52. 2014
    ..Affective temperaments can be considered the subclinical manifestations of affective disorders, which have a bidirectional relationship with cardiovascular diseases...
  67. ncbi request reprint [Creativity and mental illness]
    Zoltan Rihmer
    Orszagos Pszichiatriai es Neurologiai Intezet, III, Pszichiátriai Osztály és Kedélybetegségek Szakambulanciája, Budapest, Hungary
    Psychiatr Hung 21:288-94. 2006
    ....
  68. ncbi request reprint [Advantage of obsessive-compulsive symptoms from the aspect of individual selection and group selection: an evolutionary psychological approach to obsessive-compulsive disorder]
    Xenia Gonda
    Farmakológiai és Farmakoterápiás Intézet, Semmelweis Egyetem, Orvostudományi Kar
    Neuropsychopharmacol Hung 10:225-32. 2008
    ..The evolutionary approach to OCD is important in understanding the background factors, development and symptoms of OCD, which mean new tools in the prevention and treatment of this disorder...
  69. ncbi request reprint Suicide prevention programs through education in the frame of healthcare
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
    Psychiatr Hung 24:382-7. 2009
    ..This paper summarizes the healthcare-based educational programmes that have been shown effective in reducing suicide morbidity and mortality even in this high-risk population...
  70. doi request reprint Preliminary investigation of the possible association between arsenic levels in drinking water and suicide mortality
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Semmelweis University, Faculty of Medicine, Budapest, Hungary National Institute of Psychiatry and Addictions, Laboratory for Suicide Research and Prevention, Budapest, Hungary Electronic address
    J Affect Disord 182:23-5. 2015
    ..Arsenic-contaminated drinking water (ACDW) represents a major global public health problem. A few previous studies suggested that consuming ACDW may be associated with elevated risk for depression...
  71. ncbi request reprint Suicidal and violent behaviour in mood disorders: A major public health problem. A review for the clinician
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    Int J Psychiatry Clin Pract 14:88-94. 2010
    ..Although specific clinical studies are lacking, it is very lilely that successful acute and long-tem treatment of mood disorders can reduce the risk of violent behaviour in this patient population. ..
  72. ncbi request reprint [Adult psychiatric aspects of Niemann-Pick disease]
    Gabor Faludi
    Klinikai es Kutatasi Mentalhigienes Osztaly, Semmelweis Egyetem, Kútvölgyi Klinikai Tömb, Budapest, Hungary
    Neuropsychopharmacol Hung 15:95-103. 2013
    ....
  73. ncbi request reprint Suicide behaviour of patients treated with antidepressants
    Zoltan Rihmer
    National Institute for Psychiatry and Neurology, Budapest, Hungary
    Neuropsychopharmacol Hung 8:13-6. 2006
    ..The almost double frequency of suicidal behaviour of patients on antidepressants compared to patients on placebo; it is in sharp contrast with the 2-6 fold lower suicide risk of antidepressant treatment versus untreated patients...
  74. ncbi request reprint Effects of autogenic training on nitroglycerin-induced headaches
    Gabriella Juhasz
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK
    Headache 47:371-83. 2007
    ..To investigate the prophylactic and acute effects of autogenic training (AT) during a nitroglycerin-induced migraine attack...
  75. doi request reprint The effect of pharmacotherapy on suicide rates in bipolar patients
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Semmelweis University, Budapest, Hungary
    CNS Neurosci Ther 18:238-42. 2012
    ..In bipolar patients suicidal behavior is most likely to occur during pure or mixed depressive episodes. Since bipolar disorder is a highly recurrent illness, adequate long-term pharmacotherapy is needed to prevent suicidal behavior...
  76. ncbi request reprint Pharmacogenetics of antidepressive drugs: a way towards personalized treatment of major depressive disorder
    Shira Weizman
    Department of Clinical and Theoretical Mental Health, Semmelweis University, Budapest, Hungary
    Neuropsychopharmacol Hung 14:87-101. 2012
    ....
  77. ncbi request reprint Relationship between obsessive-compulsive symptoms and smoking habits amongst schizophrenic patients
    Peter Dome
    National Institute of Psychiatry and Neurology, Budapest, Hungary
    Psychiatry Res 144:227-31. 2006
    ..We found that the rates did not differ significantly, so we came to the conclusion that OC symptoms are not in a tight relationship with smoking habits among patients with SCH/SCHAFF...
  78. doi request reprint Investigation of circulating endothelial progenitor cells and angiogenic and inflammatory cytokines during recovery from an episode of major depression
    Peter Dome
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Faculty of Medicine, and 1st Department of Psychiatry, Nyírő Gyula Hospital, Budapest, Hungary
    J Affect Disord 136:1159-63. 2012
    ..In addition these cytokines are also involved in regulation of the vascular system. This suggests that VEGF and/or TNF may also mediate the elevated risk of CVD associated with mood disorders...
  79. doi request reprint Is drug-placebo difference in short-term antidepressant drug trials on unipolar major depression much greater than previously believed?
    Zoltan Rihmer
    Department of Clinical and Theoretical Mental Health, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    J Affect Disord 108:195-8. 2008
    ....
  80. doi request reprint A systematic review of the evidence on the treatment of rapid cycling bipolar disorder
    Konstantinos N Fountoulakis
    Third Department of Psychiatry, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Bipolar Disord 15:115-37. 2013
    ..The aim of the present study was to review the existing published randomized trials investigating the effect of treatment on patients with rapid cycling bipolar disorder...
  81. ncbi request reprint The role of hyperventilation: hypocapnia in the pathomechanism of panic disorder
    Andras Sikter
    Department of Internal Medicine, St Rokus Hospital, Budapest, Hungary
    Rev Bras Psiquiatr 29:375-9. 2007
    ..The review presented attempts to integrate three premises: hyperventilation is a physiological response to hypercapnia; hyperventilation can induce panic attacks; chronic hyperventilation is a protective mechanism against panic attacks...