David Goldsmith

Summary

Publications

  1. doi Systematic review of the evidence underlying the association between mineral metabolism disturbances and risk of fracture and need for parathyroidectomy in CKD
    David Goldsmith
    Guy s Hospital, London, UK
    Am J Kidney Dis 53:1002-13. 2009
  2. doi 2009: a requiem for rHuEPOs--but should we nail down the coffin in 2010?
    David Goldsmith
    Renal Department, Guy s Hospital, King s Health Partners, London, United Kingdom
    Clin J Am Soc Nephrol 5:929-35. 2010
  3. doi The Janus faces of ESAs: caveat Chimaera!
    Hugo Penny
    King s Health Partners AHSC, Wing Guy s Hospital, 6th Floor, Borough, London, SE1 9RT, UK
    Int Urol Nephrol 45:761-7. 2013
  4. ncbi Oral phosphate binders in CKD - is calcium the (only) answer?
    David Goldsmith
    Renal and Transplantation Department, Guy s Hospital, London, UK, and Clinic of Nephrology, C I Parhon University Hospital, Gr T Popa, University of Medicine and Pharmacy, Iasi, Romania
    Clin Nephrol 81:389-95. 2014
  5. ncbi Through the looking glass: the protein science of biosimilars
    David Goldsmith
    Renal Unit, New Guy House, Guy s Hospital, London, UK
    Clin Exp Nephrol 11:191-5. 2007
  6. doi Comparison of estimated GFR and measured GFR in prospective living kidney donors
    Thakshyanee Bhuvanakrishna
    MRC Centre for Transplantation and Renal Unit, Guy s and St Thomas NHS Foundation Trust, King s College Academic Health Partners, London, UK
    Int Urol Nephrol 47:201-8. 2015
  7. doi Long-term safety and efficacy of renin-angiotensin blockade in atherosclerotic renal artery stenosis
    Sofia Sofroniadou
    Department of Renal Medicine and Transplantation, Guy s and St Thomas NHS Foundation Trust, King s Health Partners AHSC, London, SE1 9RT, UK
    Int Urol Nephrol 44:1451-9. 2012
  8. doi Determinants of vitamin D status in long-term renal transplant patients
    Hugo Penny
    Department of Nephrology and Transplantation, Guy s and St Thomas NHS Foundation Trust, London, UK
    Clin Transplant 26:E617-23. 2012
  9. ncbi Mineral and bone disorder after renal transplantation: a review
    Hazim Sadideen
    Department of Nephrology and Transplantation, New Guy s House, Guy s Hospital, St Thomas Street, London SE1 9RT, UK
    Int Urol Nephrol 40:171-84. 2008
  10. pmc (18)F-fluoride positron emission tomography measurements of regional bone formation in hemodialysis patients with suspected adynamic bone disease
    Michelle L Frost
    Osteoporosis Unit, Division of Imaging Sciences and Biomedical Engineering, King s College London, Guy s Hospital Campus, Great Maze Pond, London, SE1 9RT, UK
    Calcif Tissue Int 93:436-47. 2013

Collaborators

Detail Information

Publications22

  1. doi Systematic review of the evidence underlying the association between mineral metabolism disturbances and risk of fracture and need for parathyroidectomy in CKD
    David Goldsmith
    Guy s Hospital, London, UK
    Am J Kidney Dis 53:1002-13. 2009
    ..Thus, a systematic review was conducted to assess method or clinical heterogeneity by comparing the design, analytical techniques, and results of studies...
  2. doi 2009: a requiem for rHuEPOs--but should we nail down the coffin in 2010?
    David Goldsmith
    Renal Department, Guy s Hospital, King s Health Partners, London, United Kingdom
    Clin J Am Soc Nephrol 5:929-35. 2010
    ..How we arrived at this crossroads is a useful illustration of how easy it is, without properly designed randomized, controlled trials, to assume that clinical benefit must follow therapeutic interventions...
  3. doi The Janus faces of ESAs: caveat Chimaera!
    Hugo Penny
    King s Health Partners AHSC, Wing Guy s Hospital, 6th Floor, Borough, London, SE1 9RT, UK
    Int Urol Nephrol 45:761-7. 2013
    ....
  4. ncbi Oral phosphate binders in CKD - is calcium the (only) answer?
    David Goldsmith
    Renal and Transplantation Department, Guy s Hospital, London, UK, and Clinic of Nephrology, C I Parhon University Hospital, Gr T Popa, University of Medicine and Pharmacy, Iasi, Romania
    Clin Nephrol 81:389-95. 2014
    ..However, not all binders are created equal in regards to their safety profiles. The potential for accumulations and toxicities does exist with very long-term continuous exposure. We discuss these issues in the course of this review. ..
  5. ncbi Through the looking glass: the protein science of biosimilars
    David Goldsmith
    Renal Unit, New Guy House, Guy s Hospital, London, UK
    Clin Exp Nephrol 11:191-5. 2007
    ..This review takes a look at how biosimilars are fundamentally different from their originator products by examining the biopharmaceutical production process and how it can influence the structure and function of the final drug product...
  6. doi Comparison of estimated GFR and measured GFR in prospective living kidney donors
    Thakshyanee Bhuvanakrishna
    MRC Centre for Transplantation and Renal Unit, Guy s and St Thomas NHS Foundation Trust, King s College Academic Health Partners, London, UK
    Int Urol Nephrol 47:201-8. 2015
    ..The aim of this study was to examine the usefulness of three GFR-estimating equations (eGFR) compared with measured GFR (mGFR) in potential living kidney donors...
  7. doi Long-term safety and efficacy of renin-angiotensin blockade in atherosclerotic renal artery stenosis
    Sofia Sofroniadou
    Department of Renal Medicine and Transplantation, Guy s and St Thomas NHS Foundation Trust, King s Health Partners AHSC, London, SE1 9RT, UK
    Int Urol Nephrol 44:1451-9. 2012
    ..The aim of the study was to assess the long-term safety, tolerability and outcomes of the use of angiotensin I-converting enzyme inhibitors (ACEis) and angiotensin receptor blockers (ARBs) in patients with ARAS...
  8. doi Determinants of vitamin D status in long-term renal transplant patients
    Hugo Penny
    Department of Nephrology and Transplantation, Guy s and St Thomas NHS Foundation Trust, London, UK
    Clin Transplant 26:E617-23. 2012
    ..Long-term RTx patients may benefit from oral vitamin D supplementation, but this requires a randomized controlled trial to confirm...
  9. ncbi Mineral and bone disorder after renal transplantation: a review
    Hazim Sadideen
    Department of Nephrology and Transplantation, New Guy s House, Guy s Hospital, St Thomas Street, London SE1 9RT, UK
    Int Urol Nephrol 40:171-84. 2008
    ....
  10. pmc (18)F-fluoride positron emission tomography measurements of regional bone formation in hemodialysis patients with suspected adynamic bone disease
    Michelle L Frost
    Osteoporosis Unit, Division of Imaging Sciences and Biomedical Engineering, King s College London, Guy s Hospital Campus, Great Maze Pond, London, SE1 9RT, UK
    Calcif Tissue Int 93:436-47. 2013
    ..81, p = 0.008) but not BFR/BS. Further studies are required to establish the sensitivity of (18)F-PET as a diagnostic tool for identifying CKD patients with ABD...
  11. doi Negative outcome studies in end-stage renal disease
    David Goldsmith
    Renal Unit, Guy s Hospital, London, UK
    Blood Purif 26:63-6. 2008
    ....
  12. pmc Impact of vitamin D supplementation on arterial vasomotion, stiffness and endothelial biomarkers in chronic kidney disease patients
    Nihil Chitalia
    Renal and Transplantation Unit, St George s Healthcare NHS Trust, London, United Kingdom Cardiovascular Research Centre, St George s, University of London, London, United Kingdom
    PLoS ONE 9:e91363. 2014
    ....
  13. pmc Regression of vascular calcification in chronic kidney disease - feasible or fantasy? a review of the clinical evidence
    Oscar Leonard
    Guy s Hospital, King s Health Partners, London, UK
    Br J Clin Pharmacol 76:560-72. 2013
    ..Aiming to manipulate the active mechanisms involved in calcium deposition, these hold hope for reversal of calcification, but are still theoretical or in early animal or human experimentation. ..
  14. doi Glomerular filtration rate in prospective living kidney donors
    Glen M Blake
    Department of Nuclear Medicine, Guy s and St Thomas NHS Foundation Trust, King s College Academic Health Partners, London, UK
    Int Urol Nephrol 45:1445-52. 2013
    ..Measurements of glomerular filtration rate (GFR) are frequently interpreted assuming a linear variation with age. Nonlinear relationships may give a better representation of the changes associated with normal ageing...
  15. doi Vitamin K status in chronic kidney disease: a report of a study and a mini-review
    Kieran Voong
    Nutristasis Laboratory, Guy s and St Thomas Hospitals Foundation Trust, London, UK
    Int Urol Nephrol 45:1339-44. 2013
    ....
  16. ncbi The metabolic syndrome following kidney transplantation
    David Goldsmith
    Renal and Transplantation Department, Guy s and St Thomas Hospital, Great Maze Pond, London, UK
    Kidney Int 78:S8-14. 2010
    ..Immunosuppressive regimens should be designed to limit exacerbation of components of the metabolic syndrome...
  17. doi Anaemia, microcytosis and sirolimus--is iron the missing link?
    Sofia Sofroniadou
    Department of Renal Medicine and Transplantation, Guy s and St Thomas NHS Foundation Trust, King s Health Partners AHSC, London, UK
    Nephrol Dial Transplant 25:1667-75. 2010
    ..Sirolimus (SRL) has been implicated in the causation of post-transplantation anaemia (PTA). It also induces profound red blood cell (RBC) microcytosis, which is poorly understood...
  18. doi Mammalian target of rapamycin (mTOR) inhibitors: potential uses and a review of haematological adverse effects
    Sofia Sofroniadou
    Department of Renal Medicine and Transplantation, Guy s and St Thomas NHS Foundation Trust, King s Health Partners Academic Health Science Centre AHSC, London, UK
    Drug Saf 34:97-115. 2011
    ..Moreover, this could expand the drugs' therapeutic applications to other disorders, and suggest novel targets for further research...
  19. doi Should patients with CKD stage 5D and biochemical evidence of secondary hyperparathyroidism be prescribed calcimimetic therapy? An ERA-EDTA position statement
    David Goldsmith
    Renal and Transplantation Department, Guy s and St Thomas Hospitals, London, UK
    Nephrol Dial Transplant 30:698-700. 2015
    ....
  20. doi Case report: making the CONN-ection: two cases of persistent hypertension and hypokalaemia following renal transplantation
    Atul Kumar
    Kings College London School of Medicine, First Floor, Hodgkin Building, Guy s Campus, London, SE1 1UL, UK
    Int Urol Nephrol 44:1577-80. 2012
    ..Abdominal MRI demonstrated a 90- and 20-mm right adrenal tumour in cases 1 and 2, respectively. For both patients, curative treatment was achieved via laparoscopic right adrenalectomy...
  21. doi Direct renin inhibitors: ONTARGET for success?
    Yasmin Pasha
    Chelsea and Westminster Hospital, Fulham Road, London, UK
    Int Urol Nephrol 41:341-55. 2009
    ....
  22. ncbi Anemia after renal transplantation
    Behdad Afzali
    Department of Nephrology and Transplantation, Guy s Hospital, London, UK
    Am J Kidney Dis 48:519-36. 2006
    ....