Cengiz Gokbulut

Summary

Publications

  1. doi request reprint Plasma pharmacokinetics, faecal excretion and efficacy of pyrantel pamoate paste and granule formulations following per os administration in donkeys naturally infected with intestinal strongylidae
    Cengiz Gokbulut
    Department of Medical Pharmacology, Faculty of Medicine, Balikesir University, Balikesir, Turkey Electronic address
    Vet Parasitol 205:186-92. 2014
  2. ncbi request reprint Comparative plasma dispositions of ivermectin and doramectin following subcutaneous and oral administration in dogs
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    Vet Parasitol 135:347-54. 2006
  3. doi request reprint The effects of different ages and dosages on the plasma disposition and hair concentration profile of ivermectin following pour-on administration in goats
    C Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Adnan Menderes University, Aydin, Turkey
    J Vet Pharmacol Ther 34:70-5. 2011
  4. doi request reprint The effect of fasting on the plasma disposition of triclabendazole following oral administration in goats
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Kampusu, Aydin, Turkey
    Res Vet Sci 89:415-7. 2010
  5. doi request reprint Comparative plasma disposition, bioavailability and efficacy of ivermectin following oral and pour-on administrations in horses
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Adnan Menderes University, Isikli Koyu, 09100 Aydin, Turkey
    Vet Parasitol 170:120-6. 2010
  6. doi request reprint Breed-related plasma disposition of ivermectin following subcutaneous administration in Kilis and Damascus goats
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, 09100 Aydin, Turkey
    Res Vet Sci 87:445-8. 2009
  7. doi request reprint Sex-related plasma disposition of ivermectin following pour-on administration in goats
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    Vet Parasitol 162:342-5. 2009
  8. doi request reprint Pharmacological assessment of netobimin as a potential anthelmintic for use in horses: plasma disposition, faecal excretion and efficacy
    C Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Aydin, Turkey
    Res Vet Sci 86:514-20. 2009
  9. doi request reprint The effect of sesame and sunflower oils on the plasma disposition of ivermectin in goats
    C Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    J Vet Pharmacol Ther 31:472-8. 2008
  10. ncbi request reprint Comparison of plasma pharmacokinetic profile of ivermectin following administration of subcutaneous injection (Baymec) and oral tablet (Efektin) in goats
    C Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    J Vet Pharmacol Ther 30:489-91. 2007

Collaborators

Detail Information

Publications22

  1. doi request reprint Plasma pharmacokinetics, faecal excretion and efficacy of pyrantel pamoate paste and granule formulations following per os administration in donkeys naturally infected with intestinal strongylidae
    Cengiz Gokbulut
    Department of Medical Pharmacology, Faculty of Medicine, Balikesir University, Balikesir, Turkey Electronic address
    Vet Parasitol 205:186-92. 2014
    ..vulgaris. Faecal cultures performed on different days from C-group confirmed the presence of the same genera. Coprocultures from treated animals revealed the presence of few larvae of Cyathostomes...
  2. ncbi request reprint Comparative plasma dispositions of ivermectin and doramectin following subcutaneous and oral administration in dogs
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    Vet Parasitol 135:347-54. 2006
    ..Considering the pharmacokinetic parameters, IVM and DRM could be used by the oral or subcutaneous route for the control of parasitic infection in dogs...
  3. doi request reprint The effects of different ages and dosages on the plasma disposition and hair concentration profile of ivermectin following pour-on administration in goats
    C Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Adnan Menderes University, Aydin, Turkey
    J Vet Pharmacol Ther 34:70-5. 2011
    ....
  4. doi request reprint The effect of fasting on the plasma disposition of triclabendazole following oral administration in goats
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Kampusu, Aydin, Turkey
    Res Vet Sci 89:415-7. 2010
    ....
  5. doi request reprint Comparative plasma disposition, bioavailability and efficacy of ivermectin following oral and pour-on administrations in horses
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Adnan Menderes University, Isikli Koyu, 09100 Aydin, Turkey
    Vet Parasitol 170:120-6. 2010
    ..In conclusion, the poor plasma availability observed after pour-on administration could result in subtherapeutic plasma concentrations, which may promote the development of drug resistance in parasites...
  6. doi request reprint Breed-related plasma disposition of ivermectin following subcutaneous administration in Kilis and Damascus goats
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, 09100 Aydin, Turkey
    Res Vet Sci 87:445-8. 2009
    ....
  7. doi request reprint Sex-related plasma disposition of ivermectin following pour-on administration in goats
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    Vet Parasitol 162:342-5. 2009
    ..78 days, respectively) were significantly longer compared with female animals (1.42 days and 3.55 days, respectively) and this suggesting that the excretion patterns of IVM in male and female animals are probably different each other...
  8. doi request reprint Pharmacological assessment of netobimin as a potential anthelmintic for use in horses: plasma disposition, faecal excretion and efficacy
    C Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Aydin, Turkey
    Res Vet Sci 86:514-20. 2009
    ..Considering the pharmacokinetic and efficacy parameters NTB could be used as an anthelmintic in horses...
  9. doi request reprint The effect of sesame and sunflower oils on the plasma disposition of ivermectin in goats
    C Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    J Vet Pharmacol Ther 31:472-8. 2008
    ..v. administration. Longer terminal elimination half-lives and resultant longer mean resident time were observed after s.c. administration of the both combinations compared with i.v. administration...
  10. ncbi request reprint Comparison of plasma pharmacokinetic profile of ivermectin following administration of subcutaneous injection (Baymec) and oral tablet (Efektin) in goats
    C Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    J Vet Pharmacol Ther 30:489-91. 2007
  11. ncbi request reprint Comparative plasma disposition of fenbendazole, oxfendazole and albendazole in dogs
    C Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine and Research and Development Laboratory, University of Adnan Menderes, Aydin, Turkey
    Vet Parasitol 148:279-87. 2007
    ..The data on the pharmacokinetic profile of OFZ presented here may contribute to evaluate its potential as an anthelmintic drug for parasite control in dogs...
  12. ncbi request reprint The effect of diet type on the plasma disposition of triclabendazole in goats
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    Res Vet Sci 82:388-91. 2007
    ..48+/-4.40 h). It is concluded that anthelmintically more active sulphoxide metabolite has higher plasma concentration when triclabendazole is administered to goats fed with concentrate feed + hay compared to grazing goats...
  13. ncbi request reprint Plasma disposition and faecal excretion of netobimin metabolites and enantiospecific disposition of albendazole sulphoxide produced in ewes
    C Gokbulut
    Department of Pharmacology and Toxicology, Research and Development Laboratory, University of Adnan Menderes, Aydin, Turkey
    Vet Res Commun 30:791-805. 2006
    ..The specific behaviour of the two enantiomers probably reflects different enantioselectivity of the enzymatic systems of the liver that are responsible for sulphoxidation and sulphonation of ABZ...
  14. doi request reprint Plasma disposition, concentration in the hair, and anthelmintic efficacy of eprinomectin after topical administration in donkeys
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu 09100 Aydin, Turkey
    Am J Vet Res 72:1639-45. 2011
    ..To investigate plasma disposition, concentration in the hair, and anthelmintic efficacy of eprinomectin after topical administration in donkeys...
  15. doi request reprint Plasma disposition, milk excretion and parasitological efficacy of mebendazole in donkeys naturally infected by Cyathostominae
    Cengiz Gokbulut
    Department of Pharmacology, Faculty of Medicine, Balikesir University, Balikesir, Turkey
    Vet Parasitol 217:95-100. 2016
    ..This trial demonstrates that MBZ oral paste at horse dosage (10 mg/kg B.W.) was effective and safety for the treatment of Cyathostominae in donkeys. Therefore, similar dosage regimens of MBZ could be used for horses and donkeys...
  16. ncbi request reprint Plasma disposition and faecal excretion of oxfendazole, fenbendazole and albendazole following oral administration to donkeys
    Cengiz Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    Vet J 172:166-72. 2006
    ..A higher metabolic capacity, first-pass effects and lower absorption of benzimidazoles in donkeys decrease bioavailability and efficacy compared to ruminants...
  17. doi request reprint Plasma dispositions of ivermectin, doramectin and moxidectin following subcutaneous administration in rabbits
    C Gokbulut
    Department of Pharmacology and Toxicology, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    Lab Anim 44:138-42. 2010
    ....
  18. ncbi request reprint Plasma pharmacokinetics and faecal excretion of ivermectin (Eqvalan paste) and doramectin (Dectomax, 1%) following oral administration in donkeys
    C Gokbulut
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    Res Vet Sci 79:233-8. 2005
    ..33 microgg(-1) - IVM, 12.12 microgg(-1) - DRM) were detected at 55.9 and 48.0 h, respectively and each compound was detected (0.05 microgg(-1)) in faeces between 11h and 9 days following oral administration in donkeys...
  19. pmc Comparative pharmacokinetics and bioavailability of albendazole sulfoxide in sheep and goats, and dose-dependent plasma disposition in goats
    Dilek Aksit
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Balikesir University, Balikesir, Turkey
    BMC Vet Res 11:124. 2015
    ..Blood samples were collected from the jugular vein at different times between 1 and 120 h after drug administrations. The plasma concentrations of ABZ-SO and its metabolites were analysed by high performance liquid chromatography...
  20. pmc The effect of surgery (Ovariohysterectomy) on the plasma disposition of meloxicam following intravenous administration in dogs
    Umit Karademir
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Isikli Koyu, Aydin, Turkey
    BMC Vet Res 12:33. 2016
    ..Blood samples were collected from all animals at various times between 1 and 96 h after the drug administrations in both phases. The drug concentrations were analysed using high performance liquid chromatography...
  21. pmc Comparative pharmacokinetics of levamisole-oxyclozanide combination in sheep and goats following per os administration
    Cengiz Gokbulut
    Department of Pharmacology, Faculty of Medicine, Balikesir University, Balikesir, Turkey Gokbulut Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Adnan Menderes, Aydin, Turkey Yalinkilinc Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Balikesir University, Balikesir, Turkey Aksit Department of Pathology and Animal Health, Faculty of Veterinary Medicine, University of Naples Federico II, Naples, Italy Veneziano
    Can J Vet Res 78:316-20. 2014
    ..However, some adverse reactions may occur since LVM has relatively very narrow therapeutic index due to its nicotine-like structure and effect. ..
  22. doi request reprint Contents and sources of DDT impurities in dicofol formulations in Turkey
    Cafer Turgut
    Faculty of Agriculture, Adnan Menderes University, 09100, Aydin, Turkey
    Environ Sci Pollut Res Int 16:214-7. 2009
    ..Specifically, DDT content in a dicofol formulation cannot exceed 0.1%. The goal of this project was to determine the DDT content in dicofol formulations used in Turkey...