Taravat Ghafourian

Summary

Publications

  1. ncbi request reprint Theoretical modeling of oral absorption of barbiturates
    Taravat Ghafourian
    School of Pharmacy, Tabriz Medical Sciences University, Iran
    Farmaco 57:565-7. 2002
  2. ncbi request reprint The use of molecular electrostatic potentials as hydrogen-bonding-donor parameters for QSAR studies
    Taravat Ghafourian
    School of Pharmacy, Tabriz Medical Sciences University, Tabriz 51664, Iran
    Farmaco 59:473-9. 2004
  3. ncbi request reprint Quantitative structure-pharmacokinetic relationship modelling: apparent volume of distribution
    Taravat Ghafourian
    Tabriz University of Medical Sciences, Tabriz 51664, Iran
    J Pharm Pharmacol 56:339-50. 2004
  4. ncbi request reprint The effect of penetration enhancers on drug delivery through skin: a QSAR study
    Taravat Ghafourian
    School of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    J Control Release 99:113-25. 2004
  5. ncbi request reprint Molecular modeling of histamine H3 receptor and QSAR studies on arylbenzofuran derived H3 antagonists
    Siavoush Dastmalchi
    School of Pharmacy, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz 51664, Iran
    J Mol Graph Model 26:834-44. 2008
  6. ncbi request reprint Comparison of electrotopological-state indices versus atomic charge and superdelocalisability indices in a QSAR study of the receptor binding properties of halogenated estradiol derivatives
    Taravat Ghafourian
    School of Pharmacy and Chemistry, Liverpool John Moores University, Liverpool L3 3AF, England
    Mol Divers 8:343-55. 2004
  7. ncbi request reprint QSPR models for the prediction of apparent volume of distribution
    Taravat Ghafourian
    Drug Design and Chemometrics Laboratory, Drug Applied Research Centre and School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Int J Pharm 319:82-97. 2006
  8. ncbi request reprint Draize rabbit eye test compatibility with eye irritation thresholds in humans: a quantitative structure-activity relationship analysis
    Michael H Abraham
    Department of Chemistry, University College London, London, England, UK
    Toxicol Sci 76:384-91. 2003
  9. ncbi request reprint Solubility prediction of paracetamol in water-ethanol-propylene glycol mixtures at 25 and 30 degrees C using practical approaches
    Abolghasem Jouyban
    Faculty of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Chem Pharm Bull (Tokyo) 56:602-6. 2008

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Theoretical modeling of oral absorption of barbiturates
    Taravat Ghafourian
    School of Pharmacy, Tabriz Medical Sciences University, Iran
    Farmaco 57:565-7. 2002
    ..Using molecular connectivity indexes was also satisfactory in modeling the absorption...
  2. ncbi request reprint The use of molecular electrostatic potentials as hydrogen-bonding-donor parameters for QSAR studies
    Taravat Ghafourian
    School of Pharmacy, Tabriz Medical Sciences University, Tabriz 51664, Iran
    Farmaco 59:473-9. 2004
    ..The efficiency of ESP+ in a QSAR was also examined. The results suggested that ESP+ was superior to the atomic charge descriptor and that the use of this parameter as the hydrogen bonding parameter in QSAR studies was successful...
  3. ncbi request reprint Quantitative structure-pharmacokinetic relationship modelling: apparent volume of distribution
    Taravat Ghafourian
    Tabriz University of Medical Sciences, Tabriz 51664, Iran
    J Pharm Pharmacol 56:339-50. 2004
    ..01 for Vd compared with 2.28 for unbound Vd). Moreover, the separation of the compounds into acids and bases did not reduce the prediction error significantly...
  4. ncbi request reprint The effect of penetration enhancers on drug delivery through skin: a QSAR study
    Taravat Ghafourian
    School of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    J Control Release 99:113-25. 2004
    ..The possible mechanisms of penetration enhancement as suggested by the QSARs will be discussed...
  5. ncbi request reprint Molecular modeling of histamine H3 receptor and QSAR studies on arylbenzofuran derived H3 antagonists
    Siavoush Dastmalchi
    School of Pharmacy, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz 51664, Iran
    J Mol Graph Model 26:834-44. 2008
    ..The results of this investigation are expected to be useful in the process of design and development of new potent H3 receptor antagonists...
  6. ncbi request reprint Comparison of electrotopological-state indices versus atomic charge and superdelocalisability indices in a QSAR study of the receptor binding properties of halogenated estradiol derivatives
    Taravat Ghafourian
    School of Pharmacy and Chemistry, Liverpool John Moores University, Liverpool L3 3AF, England
    Mol Divers 8:343-55. 2004
    ..The most accurate predictions were achieved when other molecular descriptors were also employed in the construction of the QSAR...
  7. ncbi request reprint QSPR models for the prediction of apparent volume of distribution
    Taravat Ghafourian
    Drug Design and Chemometrics Laboratory, Drug Applied Research Centre and School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Int J Pharm 319:82-97. 2006
    ..The structural descriptors in the model can be interpreted based on the known mechanisms of distribution and the molecular structures of the drugs...
  8. ncbi request reprint Draize rabbit eye test compatibility with eye irritation thresholds in humans: a quantitative structure-activity relationship analysis
    Michael H Abraham
    Department of Chemistry, University College London, London, England, UK
    Toxicol Sci 76:384-91. 2003
    ..The biophase does not resemble water or plasma, but resembles an organic solvent such as N-methylformamide...
  9. ncbi request reprint Solubility prediction of paracetamol in water-ethanol-propylene glycol mixtures at 25 and 30 degrees C using practical approaches
    Abolghasem Jouyban
    Faculty of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Chem Pharm Bull (Tokyo) 56:602-6. 2008
    ..0+/-8.7 and 55.4+/-17.8%, respectively; the corresponding values for the predicted solubilities in mixtures having a cosolvent concentration of <50% were 12.0+/-9.1 and 22.0+/-11.0%...