Seyed H Ghaffari

Summary

Publications

  1. ncbi Arsenic Trioxide Induces Apoptosis and Incapacitates Proliferation and Invasive Properties of U87MG Glioblastoma Cells through a Possible NF-κB-Mediated Mechanism
    Seyed H Ghaffari
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran E mail
    Asian Pac J Cancer Prev 17:1553-64. 2016
  2. ncbi Arsenic trioxide Alters the MicroRNA Expression Profile of U87 glioblastoma
    Fatemeh Shidfar
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Anticancer Agents Med Chem 16:247-58. 2015
  3. doi Silibinin induces apoptosis and inhibits proliferation of estrogen receptor (ER)-negative breast carcinoma cells through suppression of nuclear factor kappa B activation
    Meysam Yousefi
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Arch Iran Med 17:366-71. 2014
  4. doi Cytotoxic effect of arsenic trioxide on acute promyelocytic leukemia cells through suppression of NFkβ-dependent induction of hTERT due to down-regulation of Pin1 transcription
    Seyed H Ghaffari
    Department of Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Hematology 17:198-206. 2012
  5. pmc Cytogenetic and FMS-like tyrosine kinase 3 mutation analyses in acute promyelocytic leukemia patients
    Marjan Yaghmaie
    Dept of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modarres University, P O BOX 14115 111, Tehran
    Iran Biomed J 16:10-7. 2012
  6. doi Alteration in miRNA gene expression pattern in acute promyelocytic leukemia cell induced by arsenic trioxide: a possible mechanism to explain arsenic multi-target action
    Seyed H Ghaffari
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Tumour Biol 33:157-72. 2012
  7. doi Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP,
    Majid Momeny
    Hematology, Oncology and Bone Marrow Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Med Oncol 27:833-42. 2010
  8. doi Differential sensitivity of p44/p42-MAPK- and PI3K/Akt-targeted neuroblastoma subtypes to arsenic trioxide
    Meysam Yousefi
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Neurochem Int 63:809-17. 2013
  9. ncbi BIBR 1532 increases arsenic trioxide-mediated apoptosis in acute promyelocytic leukemia cells: therapeutic potential for APL
    Davood Bashash
    Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Iran
    Anticancer Agents Med Chem 13:1115-25. 2013
  10. doi Inhibitor of Aurora Kinase B Induces Differentially Cell Death and Polyploidy via DNA Damage Response Pathways in Neurological Malignancy: Shedding New Light on the Challenge of Resistance to AZD1152-HQPA
    Ali Zekri
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Mol Neurobiol 53:1808-23. 2016

Collaborators

  • Kamran Alimoghaddam
  • Farhad Zaker
  • Shahriar Nafissi
  • Saeed Pirouzpanah
  • Mojgan Shaiegan
  • Reza Shirkoohi
  • Mir Davood Omrani
  • Bagher Larijani
  • Ardeshir Ghavamzadeh
  • Ali Zekri
  • Majid Momeny
  • Davood Bashash
  • Meysam Yousefi
  • Marjan Yaghmaie
  • Samad Ghanizadeh-Vesali
  • Saeed Hassani
  • Reza Ghasemi
  • Mohsen Malehmir
  • Ava Safaroghli-Azar
  • Saeed Mohammadi
  • Shirin Ferdowsi
  • Majid Zaki Dizaji
  • Elham Hosseini
  • Shahin Ahmadian
  • Gholamreza Toogeh
  • Haniyeh Eyvani
  • Mohsen Nikbakht
  • Amir Valikhani
  • Samaneh Bayati
  • Naser Amirizadeh
  • Fatemeh Shidfar
  • Azam Zaghal
  • Ali Khaleghian
  • Rahim Amini
  • Mehdi Yousefi
  • Majid Zakidizaji
  • Parisa Sadreazami
  • Mohadeseh Zareii
  • Mohammad Faranoush
  • Mariska Miranda
  • Kamran Atarodi
  • Javad Tavakkoly-Bazzaz
  • Majid Kabuli
  • Nasrin Alizadeh
  • Mohammad Vaezi
  • Giovanni Valenti
  • Mohammad Hossein Modarressi
  • Negar Rezaei
  • Kamran Alimoghadam
  • Farima Moghaddaskho
  • Mehrdad Asghari Estiar
  • Ehsan Saraf Kazeruoni
  • Ghazaleh Zarrinrad
  • Sepehr Javadikooshesh
  • Mahin Nikougoftar Zarif
  • Ghasem Azizi Tabesh
  • Shahrbano Rostami
  • Mahtab Maghsoodlu
  • Hosein Teimori Naghadeh
  • Mahin Nikogoftar Zarif
  • Alireza Farshchi
  • Azita Azarkeivan
  • Behzad Poopak
  • Shiva Akbari Birgani
  • Gholamreza Tavoosidana
  • Mohammad H Modarressi
  • Arash Salmaninejad
  • Masoumeh Rostami
  • Rohellah Mirzaee
  • Rooholah Mirzaee
  • Kebria Hezave
  • Majid Mojarrad
  • Hajar Mardani
  • Maryam Kazerani
  • Masomeh Rostami
  • Mozaffar Aznab
  • Ramin Heshmat
  • Vahid Lesan
  • Mina Hajifaraj Tabrizi
  • Marjan Hajhashemi
  • Khadijeh Adabi
  • Vahid Haghpanah
  • Mehrdad Behmanesh
  • Mohammad Hussein Modarressi
  • Hossein Mozdarani
  • Bahram M Soltani
  • Razieh Yazdanparast
  • Fatemeh Naadali
  • Safiyeh Aghazadeh
  • Habibeh Ghadimi

Detail Information

Publications37

  1. ncbi Arsenic Trioxide Induces Apoptosis and Incapacitates Proliferation and Invasive Properties of U87MG Glioblastoma Cells through a Possible NF-κB-Mediated Mechanism
    Seyed H Ghaffari
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran E mail
    Asian Pac J Cancer Prev 17:1553-64. 2016
    ..Taken together, here we suggest that ATO inhibits survival and invasion of U87MG cells possibly through NF-κB-mediated inhibition of survivin and telomerase activity and NF-κB-dependent suppression of cathepsin B, MMP-2 and MMP-9. ..
  2. ncbi Arsenic trioxide Alters the MicroRNA Expression Profile of U87 glioblastoma
    Fatemeh Shidfar
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Anticancer Agents Med Chem 16:247-58. 2015
    ..This study supports the mediatory role of miRNAs in anticancer effect of ATO. ..
  3. doi Silibinin induces apoptosis and inhibits proliferation of estrogen receptor (ER)-negative breast carcinoma cells through suppression of nuclear factor kappa B activation
    Meysam Yousefi
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Arch Iran Med 17:366-71. 2014
    ..The current study was designed to evaluate the restrictive effects of pharmacological doses of silibinin on SKBR3, an ErbB2-overexpressed and ER-negative human breast carcinoma cell line...
  4. doi Cytotoxic effect of arsenic trioxide on acute promyelocytic leukemia cells through suppression of NFkβ-dependent induction of hTERT due to down-regulation of Pin1 transcription
    Seyed H Ghaffari
    Department of Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Hematology 17:198-206. 2012
    ..On aggregate, these issues indicate that ATO might preempt cell growth and proliferation in NB4 cells through suppression of Pin1-mediated NF-κB-dependent stimulation of telomerase and survivin...
  5. pmc Cytogenetic and FMS-like tyrosine kinase 3 mutation analyses in acute promyelocytic leukemia patients
    Marjan Yaghmaie
    Dept of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modarres University, P O BOX 14115 111, Tehran
    Iran Biomed J 16:10-7. 2012
    ..However, the prognostic significance of FLT3 mutations in acute promyelocytic leukemia (APL) is not firmly established...
  6. doi Alteration in miRNA gene expression pattern in acute promyelocytic leukemia cell induced by arsenic trioxide: a possible mechanism to explain arsenic multi-target action
    Seyed H Ghaffari
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Tumour Biol 33:157-72. 2012
    ..The results of this study support the hypothesis that miRNAs may play a mediatory role in eliciting the multi-target and pleiotropic action of ATO...
  7. doi Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP,
    Majid Momeny
    Hematology, Oncology and Bone Marrow Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Med Oncol 27:833-42. 2010
    ....
  8. doi Differential sensitivity of p44/p42-MAPK- and PI3K/Akt-targeted neuroblastoma subtypes to arsenic trioxide
    Meysam Yousefi
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Neurochem Int 63:809-17. 2013
    ..However, for successful strategies for the treatment of this heterogeneous tumor, other combinations approaches need to be considered to simultaneously target other NB cells. ..
  9. ncbi BIBR 1532 increases arsenic trioxide-mediated apoptosis in acute promyelocytic leukemia cells: therapeutic potential for APL
    Davood Bashash
    Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Iran
    Anticancer Agents Med Chem 13:1115-25. 2013
    ....
  10. doi Inhibitor of Aurora Kinase B Induces Differentially Cell Death and Polyploidy via DNA Damage Response Pathways in Neurological Malignancy: Shedding New Light on the Challenge of Resistance to AZD1152-HQPA
    Ali Zekri
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Mol Neurobiol 53:1808-23. 2016
    ..We suggest p53/p73 could be a key regulator of sensitivity to AZD1152-HQPA and their status should be explored in clinical response to this ongoing drug in clinical trials. ..
  11. doi Significance of AZD1152 as a potential treatment against Aurora B overexpression in acute promyelocytic leukemia
    Samad Ghanizadeh-Vesali
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Ann Hematol 95:1031-42. 2016
    ..It seems that induction of polyploidy via AZD1152 could be a novel form of anti-cancer therapy for APL that may be clinically accessible in the near future. ..
  12. doi Autocrine human growth hormone increases sensitivity of mammary carcinoma cell to arsenic trioxide-induced apoptosis
    Ali Zekri
    Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Mol Cell Endocrinol 377:84-92. 2013
    ..Our study may highlight the potential application of ATO for the treatment of patients with breast cancer, especially in those who have metastatic and chemoresistant tumor phenotype possibly due to the over expression of hGH...
  13. doi Synergistic effects of arsenic trioxide and silibinin on apoptosis and invasion in human glioblastoma U87MG cell line
    Majid Zaki Dizaji
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Neurochem Res 37:370-80. 2012
    ..This study may supply insight into the design of new combination cancer therapies to cells intrinsically less sensitive to routine therapies and suggested a new combination therapy for the highly invasive human glioma treatment...
  14. doi Multitargeting and antimetastatic potentials of silibinin in human HepG-2 and PLC/PRF/5 hepatoma cells
    Reza Ghasemi
    Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Nutr Cancer 65:590-9. 2013
    ..In conclusion, our findings suggest that silibinin could potentially function as a multitargeting antimetastatic agent and might provide new insights for HCC therapy particularly for HBV-related and/or P53-mutated HCCs...
  15. doi Telomerase inhibition by non-nucleosidic compound BIBR1532 causes rapid cell death in pre-B acute lymphoblastic leukemia cells
    Davood Bashash
    Department of Hematology, Faculty of Allied Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Leuk Lymphoma 54:561-8. 2013
    ....
  16. doi Azidothymidine hinders arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells by induction of p21 and attenuation of G2/M arrest
    Saeed Hassani
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Ann Hematol 92:1207-20. 2013
    ....
  17. doi Therapeutic efficacy of silibinin on human neuroblastoma cells: Akt and NF-κB expressions may play an important role in silibinin-induced response
    Meysam Yousefi
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Neurochem Res 37:2053-63. 2012
    ..Our results suggest that suppression of SK-N-MC cell line by silibinin may be through inhibition of Akt-mediated NF-κB1...
  18. doi AZD1152-HQPA induces growth arrest and apoptosis in androgen-dependent prostate cancer cell line (LNCaP) via producing aneugenic micronuclei and polyploidy
    Ali Zekri
    Department of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran
    Tumour Biol 36:623-32. 2015
    ..AZD1152-HQPA induces aneugenic mechanism of micronuclei production. Taken together, this study provides new insight into the direction to overcome the therapeutic impediments against prostate cancer...
  19. ncbi Silibinin inhibits invasive properties of human glioblastoma U87MG cells through suppression of cathepsin B and nuclear factor kappa B-mediated induction of matrix metalloproteinase 9
    Majid Momeny
    Hematology, Oncology and Bone Marrow Transplantation Research Center, Tehran, Iran
    Anticancer Drugs 21:252-60. 2010
    ..Furthermore, silibinin might cripple the activation of gelatinase B by cramping transcriptional and enzymatic activities of cathepsin B in U87 cells...
  20. doi Multifaceted suppression of aggressive behavior of thyroid carcinoma by all-trans retinoic acid induced re-differentiation
    Mohsen Malehmir
    Endocrinology and Metabolism Research Center EMRC, Tehran University of Medical Sciences, Tehran, Iran
    Mol Cell Endocrinol 348:260-9. 2012
    ..Altogether, ATRA treatment could hold the aggressive behavior of thyroid carcinoma in restraint and/or potentiate the effect of chemotherapy drug ATO...
  21. pmc Curcumin Veto the Effects of Osteopontin (OPN) Specific Inhibitor on Leukemic Stem Cell Colony Forming Potential via Promotion of OPN Overexpression
    Saeed Mohammadi
    Iranian Blood Transfusion Research Center, High Institute for Education and Research in Transfusion Medicine, Tehran, Iran Hematology Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Int J Hematol Oncol Stem Cell Res 10:120-9. 2016
    ....
  22. doi Inhibition of tachykinin NK1 receptor using aprepitant induces apoptotic cell death and G1 arrest through Akt/p53 axis in pre-B acute lymphoblastic leukemia cells
    Samaneh Bayati
    Institute of Biochemistry and Biophysics, University of Tehran, P O Box 13145 1384, Tehran, Iran Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Eur J Pharmacol 791:274-283. 2016
    ....
  23. doi Effects of silibinin on growth and invasive properties of human ovarian carcinoma cells through suppression of heregulin/HER3 pathway
    Majid Momeny
    Hematology Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Tumour Biol 37:3913-23. 2016
    ..Altogether, these results suggest that silibinin is a potential anti-cancer drug to inhibit proliferative and invasive characteristics of the EOC cells that exhibit an autocrine HRG/HER3 pathway. ..
  24. pmc JAK2V617F Allele Burden Measurement in Peripheral Blood of Iranian Patients with Myeloproliferative Neoplasms and Effect of Hydroxyurea on JAK2V617F Allele Burden
    Shirin Ferdowsi
    Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
    Int J Hematol Oncol Stem Cell Res 10:70-8. 2016
    ..We also aimed at determining the correlation between JAK2V617F allele burden and use of cyto reductive treatment (hydroxyurea)...
  25. doi Arsenic trioxide induces cell cycle arrest and alters DNA methylation patterns of cell cycle regulatory genes in colorectal cancer cells
    Haniyeh Eyvani
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Life Sci 167:67-77. 2016
    ....
  26. doi Survivin isoform expression in arsenic trioxide-treated acute promyelocytic leukemia cell line and patients: The odd expression pattern of survivin-2α
    Majid Zaki Dizaji
    Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Asia Pac J Clin Oncol . 2016
    ..Several survivin splice variants have been described, and none of their expressions have been defined in acute promyelocytic leukemia (APL)...
  27. doi PI3K-δ inhibition using CAL-101 exerts apoptotic effects and increases doxorubicin-induced cell death in pre-B-acute lymphoblastic leukemia cells
    Ava Safaroghli-Azar
    aDepartment of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences bHematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Anticancer Drugs . 2017
    ....
  28. doi Metabolism of arsenic trioxide in acute promyelocytic leukemia cells
    Ali Khaleghian
    Institute of Biochemistry and Biophysics IBB, University of Tehran, P O Box 13145 1384, Tehran, Iran Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    J Cell Biochem 115:1729-39. 2014
    ..Production of intracellular methylated metabolites and epigenetic changes of DNA methylation during As2O3 metabolism may contribute to the therapeutic effect of As2O3 in APL...
  29. doi Concomitant presence of JAK2 V617F mutation and BCR-ABL translocation in a pregnant woman with polycythemia vera
    Gholamreza Toogeh
    Hematology Oncology and BMT Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Med Oncol 28:1555-8. 2011
    ..This case report suggests that in a PV pregnant woman with a concomitant presence of JAK2 V617F mutation and BCR-ABL translocation, the administration of interferon during the pregnancy could lead to a safe pregnancy and delivery...
  30. doi Frequency of BCR-ABL fusion transcripts in Iranian patients with chronic myeloid leukemia
    Marjan Yaghmaie
    Hematology Oncology and Bone Marrow Transplant Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Arch Iran Med 11:247-51. 2008
    ..The objective of this study was to set up a multiplex RT-PCR assay for detection and to determine the frequency of different fusion genes in 75 Iranian patients with chronic myeloid leukemia...
  31. doi Monitoring of cytomegalovirus reactivation in bone marrow transplant recipients by real-time PCR
    Seyed H Ghaffari
    Oncology and BMT Research Center, Tehran University Medical Sciences, Shariati Hospital, Tehran, 11411, Iran
    Pathol Oncol Res 14:399-409. 2008
    ..The quantitative CMV PCR might be a useful tool for monitoring the CMV reactivation and guiding the efficacy of the CMV preemptive therapy in BMT recipients...
  32. doi Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation
    Majid Momeny
    Department of Medical Genetics, University of Tehran, Tehran, Iran
    Eur J Pharmacol 591:13-20. 2008
    ..In addition, cell growth and proliferation may be inhibited by silibinin through down-regulation of Hec1...
  33. doi Teucrium polium reversed the MCD diet-induced liver injury in rats
    Rahim Amini
    Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    Hum Exp Toxicol 30:1303-12. 2011
    ..These results indicate that the ethyl acetate fraction of T. poium effectively reversed NASH, mainly due to its strong antioxidant and anti-inflammatory properties...
  34. doi Acquired expression of osteopontin selectively promotes enrichment of leukemia stem cells through AKT/mTOR/PTEN/β-catenin pathways in AML cells
    Saeed Mohammadi
    Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
    Life Sci 152:190-8. 2016
    ..The aim of this study was to explore OPN roles in modulating curcumin-mediated LSC enrichment and survival in AML cell lines and primary CD34+/CD38- bone-marrow-derived AML cells...
  35. doi ASXL1 and JAK2V617F gene mutation screening in Iranian patients with chronic myeloid leukemia
    Amir Valikhani
    Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
    Asia Pac J Clin Oncol . 2016
    ..There were no previous studies investigating the incidence of the ASXL1 and JAK2V617F mutations in Iranian patients with CML. Consequently, this study focuses on the analysis of these mutations in patients with CML...
  36. doi Inhibition of telomerase using BIBR1532 enhances doxorubicin-induced apoptosis in pre-B acute lymphoblastic leukemia cells
    Davood Bashash
    a Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Hematology . 2017
    ....
  37. ncbi Gene amplification and overexpression of Aurora-C in breast and prostate cancer cell lines
    Ali Zekri
    Department of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran
    Oncol Res 20:241-50. 2012
    ..At DNA level, only Aurora-C showed gene amplification in breast cancer cell lines (p < 0.005). Here we provide evidence for the first time of Aurora-C overexpression and gene amplification...