A Zien

Summary

Country: Germany

Publications

  1. ncbi request reprint Analysis of gene expression data with pathway scores
    A Zien
    Institute for Algorithms and Scientific Computing, GMD German National Research Center for Information Technology, Schloss Birlinghoven, Sankt Augustin
    Proc Int Conf Intell Syst Mol Biol 8:407-17. 2000
  2. ncbi request reprint A simple iterative approach to parameter optimization
    A Zien
    GMD German National Research Center for Information Technology, Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin
    J Comput Biol 7:483-501. 2000
  3. ncbi request reprint Engineering support vector machine kernels that recognize translation initiation sites
    A Zien
    GMD SCAI, Schloss Birlinghoven, 53754 Sankt Augustin, Germany
    Bioinformatics 16:799-807. 2000
  4. ncbi request reprint Centralization: a new method for the normalization of gene expression data
    A Zien
    SCAI Institute for Algorithms and Scientific Computing, GMD German National Research Center for Information Technology, Schloss Birlinghoven, Sankt Augustin, 53754, Germany
    Bioinformatics 17:S323-31. 2001
  5. ncbi request reprint Application of parameter optimization to molecular comparison problems
    C Lemmen
    GMD German National Research Center for Information Technology, Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin, Germany
    Pac Symp Biocomput . 1999

Detail Information

Publications5

  1. ncbi request reprint Analysis of gene expression data with pathway scores
    A Zien
    Institute for Algorithms and Scientific Computing, GMD German National Research Center for Information Technology, Schloss Birlinghoven, Sankt Augustin
    Proc Int Conf Intell Syst Mol Biol 8:407-17. 2000
    ..This suggests that the combination of appropriate scoring functions with the systematic generation of pathways can be used in order to select the most interesting pathways based on gene expression measurements...
  2. ncbi request reprint A simple iterative approach to parameter optimization
    A Zien
    GMD German National Research Center for Information Technology, Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin
    J Comput Biol 7:483-501. 2000
    ..These results show the general validity of the optimized weights for the given threading program and the associated scoring contributions...
  3. ncbi request reprint Engineering support vector machine kernels that recognize translation initiation sites
    A Zien
    GMD SCAI, Schloss Birlinghoven, 53754 Sankt Augustin, Germany
    Bioinformatics 16:799-807. 2000
    ..In order to extract protein sequences from nucleotide sequences, it is an important step to recognize points at which regions start that code for proteins. These points are called translation initiation sites (TIS)...
  4. ncbi request reprint Centralization: a new method for the normalization of gene expression data
    A Zien
    SCAI Institute for Algorithms and Scientific Computing, GMD German National Research Center for Information Technology, Schloss Birlinghoven, Sankt Augustin, 53754, Germany
    Bioinformatics 17:S323-31. 2001
    ..First, for each pair of arrays the quotient of the constants of proportionality is estimated. Second, from the resulting matrix of pairwise quotients an optimally consistent scaling of the samples is computed...
  5. ncbi request reprint Application of parameter optimization to molecular comparison problems
    C Lemmen
    GMD German National Research Center for Information Technology, Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin, Germany
    Pac Symp Biocomput . 1999
    ..Using well established evaluation methods, it can be shown that the results of both comparison methods are significantly improved by systematically choosing appropriate weights for the scoring function contributions...