Derek Zieker

Summary

Country: Germany

Publications

  1. ncbi request reprint cDNA microarray analysis reveals novel candidate genes expressed in human peripheral blood following exhaustive exercise
    Derek Zieker
    Department of Transfusions Medicine, University of Tuebingen, Germany
    Physiol Genomics 23:287-94. 2005
  2. doi request reprint PGK1 a potential marker for peritoneal dissemination in gastric cancer
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, Tuebingen, Germany
    Cell Physiol Biochem 21:429-36. 2008
  3. doi request reprint Induction of tumor stem cell differentiation--novel strategy to overcome therapy resistance in gastric cancer
    Derek Zieker
    Department of General and Transplant Surgery and Comprehensive Cancer Center, University of Tuebingen, Hoppe Seyler Strasse 3, 72076 Tuebingen, Germany
    Langenbecks Arch Surg 398:603-8. 2013
  4. doi request reprint Circadian expression of clock- and tumor suppressor genes in human oral mucosa
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, University of Tuebingen, Tuebingen, Germany
    Cell Physiol Biochem 26:155-66. 2010
  5. pmc Phosphoglycerate kinase 1 a promoting enzyme for peritoneal dissemination in gastric cancer
    Derek Zieker
    Department of General Visceral, Transplant Surgery Comprehensive Cancer Center, University of Tuebingen, D 72076 Tuebingen, Germany
    Int J Cancer 126:1513-20. 2010
  6. doi request reprint Phosphoglycerate kinase 1 promoting tumor progression and metastasis in gastric cancer - detected in a tumor mouse model using positron emission tomography/magnetic resonance imaging
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, University of Tuebingen, Tuebingen, Germany
    Cell Physiol Biochem 26:147-54. 2010
  7. pmc Simultaneous adrenal and extra-adrenal myelolipoma - an uncommon incident: case report and review of the literature
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, Tuebingen, Germany
    World J Surg Oncol 6:72. 2008
  8. ncbi request reprint CDNA-microarray analysis as a research tool for expression profiling in human peripheral blood following exercise
    Derek Zieker
    Institute of Clinical and Experimental Transfusion Medicine, University of Tuebingen, Germany
    Exerc Immunol Rev 11:86-96. 2005
  9. doi request reprint Lactate modulates gene expression in human mesenchymal stem cells
    Derek Zieker
    Department of General and Transplant Surgery, University of Tuebingen, Tuebingen, Germany
    Langenbecks Arch Surg 393:297-301. 2008
  10. ncbi request reprint Impact of endotoxin exposure after exhausting exercise on the immune system in solid organ transplant recipients
    Ingmar Königsrainer
    Department of General Visceral and Transplant Surgery, University of Tuebingen, D 72076 Tuebingen, Germany
    Exerc Immunol Rev 18:177-83. 2012

Detail Information

Publications33

  1. ncbi request reprint cDNA microarray analysis reveals novel candidate genes expressed in human peripheral blood following exhaustive exercise
    Derek Zieker
    Department of Transfusions Medicine, University of Tuebingen, Germany
    Physiol Genomics 23:287-94. 2005
    ..The study shows cDNA microarray expression analysis as a reliable systematic instrument to complete the list of candidate genes that may play a role in exhaustive exercise-induced modulation of the immune response...
  2. doi request reprint PGK1 a potential marker for peritoneal dissemination in gastric cancer
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, Tuebingen, Germany
    Cell Physiol Biochem 21:429-36. 2008
    ..The mechanisms that mediate peritoneal carcinomatosis in diffuse primary gastric tumours require definition...
  3. doi request reprint Induction of tumor stem cell differentiation--novel strategy to overcome therapy resistance in gastric cancer
    Derek Zieker
    Department of General and Transplant Surgery and Comprehensive Cancer Center, University of Tuebingen, Hoppe Seyler Strasse 3, 72076 Tuebingen, Germany
    Langenbecks Arch Surg 398:603-8. 2013
    ..In this study, we investigated if PGK1 is a promising candidate in inducing stem cell differentiation in gastric cancer...
  4. doi request reprint Circadian expression of clock- and tumor suppressor genes in human oral mucosa
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, University of Tuebingen, Tuebingen, Germany
    Cell Physiol Biochem 26:155-66. 2010
    ..To further elucidate the role circadian clocks have in cellular growth control, tumor suppression and cancer treatment, it is revealing to know how clock genes and clock-controlled genes are regulated in healthy humans...
  5. pmc Phosphoglycerate kinase 1 a promoting enzyme for peritoneal dissemination in gastric cancer
    Derek Zieker
    Department of General Visceral, Transplant Surgery Comprehensive Cancer Center, University of Tuebingen, D 72076 Tuebingen, Germany
    Int J Cancer 126:1513-20. 2010
    ..Thus, PGK1 may serve as prognostic marker and/or be a potential therapeutic target to prevent dissemination of gastric carcinoma cells into the peritoneum...
  6. doi request reprint Phosphoglycerate kinase 1 promoting tumor progression and metastasis in gastric cancer - detected in a tumor mouse model using positron emission tomography/magnetic resonance imaging
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, University of Tuebingen, Tuebingen, Germany
    Cell Physiol Biochem 26:147-54. 2010
    ....
  7. pmc Simultaneous adrenal and extra-adrenal myelolipoma - an uncommon incident: case report and review of the literature
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, Tuebingen, Germany
    World J Surg Oncol 6:72. 2008
    ..Other soft tissue tumours such as well-differentiated liposarcomas appear morphological almost identical. Preoperative imaging and especially biopsy are important tools to diagnose these lesions...
  8. ncbi request reprint CDNA-microarray analysis as a research tool for expression profiling in human peripheral blood following exercise
    Derek Zieker
    Institute of Clinical and Experimental Transfusion Medicine, University of Tuebingen, Germany
    Exerc Immunol Rev 11:86-96. 2005
    ..These data suggest that gene expression fingerprints can serve as a powerful research tool to design novel strategies for diagnosis and treatment of exercise related injury and stress...
  9. doi request reprint Lactate modulates gene expression in human mesenchymal stem cells
    Derek Zieker
    Department of General and Transplant Surgery, University of Tuebingen, Tuebingen, Germany
    Langenbecks Arch Surg 393:297-301. 2008
    ..Recently, it has been shown in vivo that lactate is also able to favour homing of stem cells. The aim of this investigation was to test the hypothesis that lactate has an impact on gene expression of mesenchymal stem cells (MSC)...
  10. ncbi request reprint Impact of endotoxin exposure after exhausting exercise on the immune system in solid organ transplant recipients
    Ingmar Königsrainer
    Department of General Visceral and Transplant Surgery, University of Tuebingen, D 72076 Tuebingen, Germany
    Exerc Immunol Rev 18:177-83. 2012
    ..Merging our previous data with these recent findings it should be discussed if transplant recipients need to reduce their immunosuppressive medication before performing exhaustive exercise...
  11. pmc Experience after 100 patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
    Ingmar Königsrainer
    Department of Surgery, University of Tubingen, Hoppe Seyler Strasse 3, D 72076 Tubingen, Germany
    World J Gastroenterol 18:2061-6. 2012
    ..To investigate perioperative patient morbidity/mortality and outcome after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)...
  12. ncbi request reprint Influence of exhaustive exercise on the immune system in solid organ transplant recipients
    Ingmar Königsrainer
    Department of General Visceral and Transplant Surgery, University of Tuebingen, D 72076 Tuebingen, Germany
    Exerc Immunol Rev 16:184-93. 2010
    ....
  13. doi request reprint Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancer
    Sufian S Ahmad
    Department of General, Visceral and Transplantation Surgery, University of Tubingen, D 72076 Tubingen, Germany
    Int J Oncol 43:586-90. 2013
    ..Furthermore, we propose several genes induced by PGK1 that could account for cell migration, mainly EGR1 and CYR61 together with the transcription factors FOS and JUN...
  14. doi request reprint Cytoreductive surgery and HIPEC in peritoneal recurrent ovarian cancer: experience and lessons learned
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Langenbecks Arch Surg 396:1077-81. 2011
    ..De novo cytoreductive surgery is crucial with the potential to improve prognosis, especially when combined with hyperthermic intraperitoneal chemotherapy (HIPEC)...
  15. pmc MSH2 and CXCR4 involvement in malignant VIPoma
    Sven Muller
    Department of General, Visceral and Transplant Surgery, Tubingen, Germany
    World J Surg Oncol 10:264. 2012
    ..1 per million per year. The molecular mechanisms that mediate development of VIPomas are poorly investigated and require definition...
  16. doi request reprint Lactate influences the gene expression profile of human mesenchymal stem cells (hMSC) in a dose dependant manner
    Carl Christoph Schneider
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, Tuebingen, Germany
    Cell Physiol Biochem 30:1547-56. 2012
    ..Lately it has been shown that lactate, in vivo, plays an important role in homing of stem cells. With this work we aimed to show the influence of lactate on the gene expressionprofile of human mesenchymal stem cells (hMSC)...
  17. doi request reprint Local peritonectomy highly attracts free floating intraperitoneal colorectal tumour cells in a rat model
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, University of Tubingen, Germany
    Cell Physiol Biochem 23:371-8. 2009
    ..Tumour recurrence may occur early after surgery. One potential mechanism is the ability of peritoneal lesions to attract tumour cells...
  18. doi request reprint Surgery of colorectal carcinoma in patients aged over 80
    Claudius Falch
    Department of Surgery, Comprehensive Cancer Center, University of Tubingen, Hoppe Seyler Strasse 3, Tubingen, Germany
    Onkologie 32:10-6. 2009
    ..The incidence of colorectal carcinoma increases rapidly in aged patients. We investigated retrospectively the differences in treatment relative to the patients' age...
  19. doi request reprint Impact of risk factors for prolonged operative time in laparoscopic cholecystectomy
    Marty Zdichavsky
    Department of General, Visceral and Transplant Surgery, University Hospital Tuebingen, Tuebingen, Germany
    Eur J Gastroenterol Hepatol 24:1033-8. 2012
    ..The aim of this study was to identify the risk factors for prolonged operative times to minimize perioperative morbidity and optimize clinical management...
  20. doi request reprint Cytostatic activity of the duplex drug linking 2'-deoxy-5-fluorouridine (5FdU) with 3'-C-ethynylcytidine (ECyd) against gastric adenocarcinoma cell lines
    Jürgen Weinreich
    Department of General, Visceral and Transplant Surgery, University of Tubingen, Tubingen, Germany
    Invest New Drugs 29:1294-302. 2011
    ..Due to its high cytostatic potential the duplex drug, which covalently links two active anticancer compounds, could be a new therapeutic alternative for chemotherapy in gastric cancer, currently treated with different combinations...
  21. doi request reprint (18)F-FDG-PET/CT to select patients with peritoneal carcinomatosis for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
    Christina Pfannenberg
    Department of Radiology and Nuclear Medicine, University of Tuebingen, Tubingen, Germany
    Ann Surg Oncol 16:1295-303. 2009
    ..This study was designed to predict tumor load in patients with PC using dual-modality (18)FDG-PET/CT and to compare the results with those of PET and CT alone by correlating imaging findings with intraoperative staging...
  22. doi request reprint IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism
    Stefan Lob
    Department of General, Visceral and Transplant Surgery, University Hospital of Tubingen, Tubingen, Germany
    Cancer Immunol Immunother 58:153-7. 2009
    ..The levo-isoform (L-1MT) blocks IDO1, whereas dextro-1MT (D-1MT), which is used in clinical trials, inhibits IDO2. Here we analyze IDO2 expression in human cancer cells and the impact of both 1-MT isoforms on IDO activity...
  23. doi request reprint A pancreas-preserving technique for the management of symptomatic pancreatic anastomotic insufficiency refractory to conservative treatment after pancreas head resection
    Ingmar Königsrainer
    Department of General, Visceral, and Transplant Surgery, Tubingen University Hospital, Hoppe Seyler Strasse 3, 72076, Tubingen, Germany
    Langenbecks Arch Surg 395:693-6. 2010
    ..Management of symptomatic pancreatic anastomotic insufficiency after pancreas head resection remains controversial. Completion pancreatectomy as one frequently performed option is associated with poor prognosis...
  24. doi request reprint Do patient- and tumor-related factors predict the peritoneal spread of pancreatic adenocarcinoma?
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, University of Tübingen Comprehensive Cancer Center, Hoppe Seyler Strasse 3, 72076, Tubingen, Germany
    Surg Today 44:260-3. 2014
    ..However, peritoneal spread cannot be reliably detected radiographically during preoperative tumor staging...
  25. ncbi request reprint Gender- and menstrual phase dependent regulation of inflammatory gene expression in response to aerobic exercise
    Hinnak Northoff
    Institute for Clinical and Experimental Transfusion Medicine IKET, University Tübingen, Germany
    Exerc Immunol Rev 14:86-103. 2008
    ..This finding accentuates a need for careful consideration of the female cyclic phase when investigating women in exercise immunology studies. Our results may also have implications relevant to other forms of stress in females...
  26. doi request reprint Morbid obesity and subsequent pancreatic cancer: pylorus-preserving pancreatoduodenectomy after laparoscopic sleeve gastrectomy
    Markus A Küper
    Department of General, Visceral, and Transplantation Surgery, Comprehensive Cancer Center, University of Tubingen, Hoppe Seyler Strasse 3, 72076, Tubingen, Germany
    Obes Surg 19:385-8. 2009
    ..In addition, there is a need for epidemiological studies of patients who undergo bariatric surgery and subsequently develop cancer...
  27. doi request reprint The Over-The-Scope Clip (OTSC) for the treatment of gastrointestinal bleeding, perforations, and fistulas
    Andreas Kirschniak
    Department of General, Visceral and Transplantation Surgery, University of Tubingen, Hoppe Seyler Straße 3, 72072 Tubingen, Germany
    Surg Endosc 25:2901-5. 2011
    ..The aim of this retrospective study was to analyze the therapeutic results of the performed treatments...
  28. pmc Hemangiopericytoma/solitary fibrous tumor of the greater omentum: A case report and review of the literature
    Rami Archid
    Department of General, Visceral and Transplant Surgery, Eberhard Karls University Hospital Tuebingen, Germany Electronic address
    Int J Surg Case Rep 23:160-2. 2016
    ..Hemangiopericytoma (HPC) has been first described in 1942 by Stout as a tumor originating from the capillary surrounding pericytes. It is known to occur in any anatomical site, especially the extremities and retroperitoneum...
  29. doi request reprint High success rate for augmentation compression plating leaving the nail in situ for aseptic diaphyseal tibial nonunions
    Atesch Ateschrang
    Department of Traumatology and Reconstructive Surgery, Berufsgenossenschaftliche Unfallklinik Tübingen, Eberhard Karls Universitat Tubingen, Tubingen, Germany
    J Orthop Trauma 27:145-9. 2013
    ..To evaluate adjunctive compression plating leaving the previously unreamed inserted intramedullary nail (URIMN) in situ for treating a resultant diaphyseal tibial nonunion...
  30. doi request reprint Exchange reamed nailing compared to augmentation compression plating leaving the inserted nail in situ in the treatment of aseptic tibial non-union: a two-centre study
    Atesch Ateschrang
    Department of Traumatology and Reconstructive Surgery, Berufsgenossenschaftliche Unfallklinik Tübingen, University Hospital, Eberhard Karls Universitat Tubingen, Schnarrenbergstr 95, 72076, Tubingen, Germany
    Wien Klin Wochenschr 125:244-53. 2013
    ..ACP, so that this trial compares ACP leaving the already inserted un-reamed nail in situ against ERN in the treatment of aseptic tibial non-union, analysing success rate, time for union and operation time...
  31. doi request reprint The gut is not only the target but a source of inflammatory mediators inhibiting gastrointestinal motility during sepsis
    Ingmar Königsrainer
    University of Tubingen, Department of General, Visceral and Transplant Surgery, Hoppe Seyler Strasse 3, Tubingen, Germany
    Cell Physiol Biochem 28:753-60. 2011
    ..Sepsis is a common problem in intensive care patients leading to multi-organ failure and gastrointestinal paralysis...
  32. pmc Early functional postoperative therapy of distal radius fracture with a dynamic orthosis: results of a prospective randomized cross-over comparative study
    Fabian M Stuby
    BG Trauma Center, University of Tuebingen, Schnarrenbergstrasse 95, D 72076, Tuebingen, Germany
    PLoS ONE 10:e0117720. 2015
    ..After week 4 the devices were removed in both groups. Follow-up exams were performed after postoperative weeks 1, 2, 4 and 12...
  33. doi request reprint Response to preoperative therapy in upper gastrointestinal cancers
    Björn L D M Brücher
    Department of Surgery, Comprehensive Cancer Center, University of Tubingen, Hoppe Seyler Strasse 3, Tubingen, Germany
    Ann Surg Oncol 16:878-86. 2009
    ..As patients with upper gastrointestinal cancers often undergo multimodal therapy, it is therefore imperative that new definitions for assessing the response to preoperative therapy be established...