Wolfgang Wirth

Summary

Country: Germany

Publications

  1. doi A three-dimensional quantitative method to measure meniscus shape, position, and signal intensity using MR images: a pilot study and preliminary results in knee osteoarthritis
    Wolfgang Wirth
    Paracelsus Medical University, Salzburg, Austria
    Magn Reson Med 63:1162-71. 2010
  2. doi A technique for regional analysis of femorotibial cartilage thickness based on quantitative magnetic resonance imaging
    Wolfgang Wirth
    Chondrometrics GmbH, Ulrichshöglerstr 23, 83404 Ainring, Germany
    IEEE Trans Med Imaging 27:737-44. 2008
  3. pmc Spatial patterns of cartilage loss in the medial femoral condyle in osteoarthritic knees: data from the Osteoarthritis Initiative
    Wolfgang Wirth
    Chondrometrics GmbH, Ainring, Germany
    Magn Reson Med 63:574-81. 2010
  4. pmc Magnetic resonance imaging-based cartilage loss in painful contralateral knees with and without radiographic joint space narrowing: Data from the Osteoarthritis Initiative
    Felix Eckstein
    Paracelsus Medical University, Salzburg, Austria, and Chondrometrics, Ainring, Germany
    Arthritis Rheum 61:1218-25. 2009
  5. pmc Rates of change and sensitivity to change in cartilage morphology in healthy knees and in knees with mild, moderate, and end-stage radiographic osteoarthritis: results from 831 participants from the Osteoarthritis Initiative
    Felix Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Arthritis Care Res (Hoboken) 63:311-9. 2011
  6. doi Femorotibial subchondral bone area and regional cartilage thickness: a cross-sectional description in healthy reference cases and various radiographic stages of osteoarthritis in 1,003 knees from the Osteoarthritis Initiative
    Richard B Frobell
    Paracelsus Medical University, Salzburg, Austria
    Arthritis Care Res (Hoboken) 62:1612-23. 2010
  7. doi Thigh muscle cross-sectional areas and strength in advanced versus early painful osteoarthritis: an exploratory between-knee, within-person comparison in osteoarthritis initiative participants
    Anja Ruhdorfer
    Paracelsus Medical University, A5020 Salzburg, Austria
    Arthritis Care Res (Hoboken) 65:1034-42. 2013
  8. doi Longitudinal quantitative MR imaging of cartilage morphology in the presence of gadopentetate dimeglumine (Gd-DTPA)
    Felix Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Magn Reson Med 61:975-80. 2009
  9. doi Patterns of femorotibial cartilage loss in knees with neutral, varus, and valgus alignment
    Felix Eckstein
    Paracelsus Medical University, Salzburg, Austria
    Arthritis Rheum 59:1563-70. 2008
  10. pmc Comparison of radiographic joint space width and magnetic resonance imaging for prediction of knee replacement: A longitudinal case-control study from the Osteoarthritis Initiative
    Felix Eckstein
    Institute of Anatomy, Paracelsus Medical University Salzburg and Nuremberg Austria and Chondrometrics GmbH, Ainring, Germany
    Eur Radiol 26:1942-51. 2016

Collaborators

Detail Information

Publications34

  1. doi A three-dimensional quantitative method to measure meniscus shape, position, and signal intensity using MR images: a pilot study and preliminary results in knee osteoarthritis
    Wolfgang Wirth
    Paracelsus Medical University, Salzburg, Austria
    Magn Reson Med 63:1162-71. 2010
    ..These results need to be confirmed in larger cohorts, preferably under weight-bearing conditions...
  2. doi A technique for regional analysis of femorotibial cartilage thickness based on quantitative magnetic resonance imaging
    Wolfgang Wirth
    Chondrometrics GmbH, Ulrichshöglerstr 23, 83404 Ainring, Germany
    IEEE Trans Med Imaging 27:737-44. 2008
    ..In longitudinal studies, this technique may substantially enhance the ability of quantitative MRI to monitor structural changes in osteoarthritis at narrow time intervals...
  3. pmc Spatial patterns of cartilage loss in the medial femoral condyle in osteoarthritic knees: data from the Osteoarthritis Initiative
    Wolfgang Wirth
    Chondrometrics GmbH, Ainring, Germany
    Magn Reson Med 63:574-81. 2010
    ..32) but was minimally affected by medial-lateral trimming. In conclusion, the greatest sensitivity to change was achieved when analyzing the posterior aspect of the central, weight-bearing MF...
  4. pmc Magnetic resonance imaging-based cartilage loss in painful contralateral knees with and without radiographic joint space narrowing: Data from the Osteoarthritis Initiative
    Felix Eckstein
    Paracelsus Medical University, Salzburg, Austria, and Chondrometrics, Ainring, Germany
    Arthritis Rheum 61:1218-25. 2009
    ....
  5. pmc Rates of change and sensitivity to change in cartilage morphology in healthy knees and in knees with mild, moderate, and end-stage radiographic osteoarthritis: results from 831 participants from the Osteoarthritis Initiative
    Felix Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Arthritis Care Res (Hoboken) 63:311-9. 2011
    ..To study the longitudinal rate of (and sensitivity to) change of knee cartilage thickness across defined stages of radiographic osteoarthritis (OA), specifically healthy knees and knees with end-stage radiographic OA...
  6. doi Femorotibial subchondral bone area and regional cartilage thickness: a cross-sectional description in healthy reference cases and various radiographic stages of osteoarthritis in 1,003 knees from the Osteoarthritis Initiative
    Richard B Frobell
    Paracelsus Medical University, Salzburg, Austria
    Arthritis Care Res (Hoboken) 62:1612-23. 2010
    ..To identify structural differences in total subchondral bone area (tAB) and cartilage thickness between healthy reference knees and knees with radiographic osteoarthritis (OA)...
  7. doi Thigh muscle cross-sectional areas and strength in advanced versus early painful osteoarthritis: an exploratory between-knee, within-person comparison in osteoarthritis initiative participants
    Anja Ruhdorfer
    Paracelsus Medical University, A5020 Salzburg, Austria
    Arthritis Care Res (Hoboken) 65:1034-42. 2013
    ....
  8. doi Longitudinal quantitative MR imaging of cartilage morphology in the presence of gadopentetate dimeglumine (Gd-DTPA)
    Felix Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Magn Reson Med 61:975-80. 2009
    ....
  9. doi Patterns of femorotibial cartilage loss in knees with neutral, varus, and valgus alignment
    Felix Eckstein
    Paracelsus Medical University, Salzburg, Austria
    Arthritis Rheum 59:1563-70. 2008
    ..We investigated the pattern of cartilage loss in neutral, varus, and valgus knees...
  10. pmc Comparison of radiographic joint space width and magnetic resonance imaging for prediction of knee replacement: A longitudinal case-control study from the Osteoarthritis Initiative
    Felix Eckstein
    Institute of Anatomy, Paracelsus Medical University Salzburg and Nuremberg Austria and Chondrometrics GmbH, Ainring, Germany
    Eur Radiol 26:1942-51. 2016
    ..To evaluate whether change in fixed-location measures of radiographic joint space width (JSW) and cartilage thickness by MRI predict knee replacement...
  11. pmc Greater Lateral Femorotibial Cartilage Loss in Osteoarthritis Initiative Participants With Incident Total Knee Arthroplasty: A Prospective Cohort Study
    Wolfgang Hitzl
    Paracelsus Medical University, Salzburg, Austria
    Arthritis Care Res (Hoboken) 67:1481-6. 2015
    ..To explore whether baseline to 12-month followup change in femorotibial cartilage thickness differs between subjects who received a total knee arthroplasty (TKA) between 24 and 60 months from those without TKA (non-TKA)...
  12. ncbi Longitudinal (one-year) change in cartilage thickness in knees with early knee osteoarthritis: A within-person between-knee comparison
    Sebastian Cotofana
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, and Chondrometrics GmbH, Ainring, Germany
    Arthritis Care Res (Hoboken) 66:636-41. 2014
    ..The observed greater variability in longitudinal thickness change in early ROA knees (but not in non-ROA knees) might be due to cartilage thickening and thinning occurring simultaneously in these knees...
  13. doi Meniscus body position, size, and shape in persons with and persons without radiographic knee osteoarthritis: quantitative analyses of knee magnetic resonance images from the osteoarthritis initiative
    Andrea Wenger
    Paracelsus Medical University, Salzburg, Austria
    Arthritis Rheum 65:1804-11. 2013
    ..To quantitatively evaluate the position, size, and shape of the menisci in subjects with radiographic knee osteoarthritis (OA) compared to subjects without OA, using magnetic resonance imaging (MRI)...
  14. pmc Cartilage thickening in early radiographic knee osteoarthritis: a within-person, between-knee comparison
    Sebastian Cotofana
    Paracelsus Medical University, Salzburg, Austria
    Arthritis Care Res (Hoboken) 64:1681-90. 2012
    ..Based on previous results, the external weight-bearing medial femoral condyle (ecMF) and external weight-bearing lateral femoral condyle (ecLF) subregions were selected as primary end points...
  15. pmc Relationship of compartment-specific structural knee status at baseline with change in cartilage morphology: a prospective observational study using data from the osteoarthritis initiative
    Felix Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, A5020 Salzburg, Austria
    Arthritis Res Ther 11:R90. 2009
    ....
  16. pmc Greater rates of cartilage loss in painful knees than in pain-free knees after adjustment for radiographic disease stage: data from the osteoarthritis initiative
    Felix Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Arthritis Rheum 63:2257-67. 2011
    ..To investigate whether rates of cartilage loss differ in knees with frequent baseline pain versus those without pain, after adjustment for radiographic osteoarthritis (OA) stage...
  17. doi Recent advances in osteoarthritis imaging--the osteoarthritis initiative
    Felix Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Strubergasse 21, A 5020, Salzburg, Austria
    Nat Rev Rheumatol 8:622-30. 2012
    ....
  18. pmc In vivo measures of cartilage deformation: patterns in healthy and osteoarthritic female knees using 3T MR imaging
    Sebastian Cotofana
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Strubergasse 21, A5020, Salzburg, Austria
    Eur Radiol 21:1127-35. 2011
    ..To explore and to compare the magnitude and spatial pattern of in vivo femorotibial cartilage deformation in healthy and in osteoarthritic (OA) knees...
  19. doi Longitudinal sensitivity to change of MRI-based muscle cross-sectional area versus isometric strength analysis in osteoarthritic knees with and without structural progression: pilot data from the Osteoarthritis Initiative
    Torben Dannhauer
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Strubergasse 21, 5020, Salzburg, Austria
    MAGMA 27:339-47. 2014
    ....
  20. doi Association of thigh muscle strength with knee symptoms and radiographic disease stage of osteoarthritis: data from the Osteoarthritis Initiative
    Anja Ruhdorfer
    Paracelsus Medical University, Salzburg, Austria
    Arthritis Care Res (Hoboken) 66:1344-53. 2014
    ..To determine whether thigh muscle strength differs between symptomatic and asymptomatic knees, and/or different radiographic strata of knee osteoarthritis (KOA)...
  21. doi Thigh Muscle Strength Predicts Knee Replacement Risk Independent of Radiographic Disease and Pain in Women: Data From the Osteoarthritis Initiative
    Adam G Culvenor
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria, and La Trobe University, Bundoora Campus, Melbourne, Victoria, Australia
    Arthritis Rheumatol 68:1145-55. 2016
    ..To determine whether thigh muscle strength predicts the risk of undergoing knee replacement surgery, independent of radiographic severity of osteoarthritis and pain...
  22. pmc Brief report: intraarticular sprifermin not only increases cartilage thickness, but also reduces cartilage loss: location-independent post hoc analysis using magnetic resonance imaging
    Felix Eckstein
    Institute of Anatomy, Paracelsus Medical University Salzburg and Nuremberg, Salzburg, Austria and Chondrometrics GmbH, Ainring, Germany
    Arthritis Rheumatol 67:2916-22. 2015
    ....
  23. doi Quantitative relationship of thigh adipose tissue with pain, radiographic status, and progression of knee osteoarthritis: longitudinal findings from the osteoarthritis initiative
    Torben Dannhauer
    From the Institute of Anatomy, Paracelsus Medical University Salzburg and Nuremberg, Salzburg, Austria
    Invest Radiol 50:268-74. 2015
    ..Specifically, we examined relationships with frequent knee pain, various radiographic strata, and structural progression status of KOA...
  24. doi Longitudinal change in femorotibial cartilage thickness and subchondral bone plate area in male and female adolescent vs. mature athletes
    Felix Eckstein
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria Electronic address
    Ann Anat 196:150-7. 2014
    ..Mature (former) athletes displayed high rates of (lateral) femorotibial cartilage loss, potentially due to a high prevalence of knee injuries...
  25. pmc Interobserver reproducibility of quantitative meniscus analysis using coronal multiplanar DESS and IWTSE MR imaging
    Kristina Siorpaes
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Magn Reson Med 67:1419-26. 2012
    ..Quantitative meniscus measures from double echo steady state and intermediately-weighted turbo spin-echo were highly correlated (r = 0.71 to 0.99 for the medial meniscus)...
  26. ncbi Accuracy and precision of quantitative assessment of cartilage morphology by magnetic resonance imaging at 3.0T
    Felix Eckstein
    Paracelsus Private Medical University, Salzburg, Austria
    Arthritis Rheum 52:3132-6. 2005
    ..5T. The aim of this study was to evaluate the precision of quantitative MRI assessments of human cartilage morphology at 3.0T and to correlate the measurements at 3.0T with validated measurements at 1.5T...
  27. pmc Predictive Capacity of Thigh Muscle Strength in Symptomatic and/or Radiographic Knee Osteoarthritis Progression: Data from the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium
    Adam G Culvenor
    From the Institute of Anatomy, Paracelsus Medical University Salzburg and Nuremberg, Salzburg, Austria AGC, WW, MR, FE School of Allied Health, La Trobe University, Bundoora, Australia AGC Chondrometrics GmbH, Ainring, Germany WW, FE and Rheumatology Department, Royal North Shore Hospital and Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia DJH
    Am J Phys Med Rehabil 95:931-938. 2016
    ....
  28. doi Sex- and age-dependence of region- and layer-specific knee cartilage composition (spin-spin-relaxation time) in healthy reference subjects
    Wolfgang Wirth
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria Chondrometrics GmbH, Ainring, Germany Electronic address
    Ann Anat 210:1-8. 2016
    ..The findings suggest that a common, non-sex-specific set of layer-and region-specific T2 reference values can be used to identify compositional pathology in joint disease for this age group...
  29. doi Longitudinal Change in Thigh Muscle Strength Prior to and Concurrent With Minimum Clinically Important Worsening or Improvement in Knee Function: Data From the Osteoarthritis Initiative
    Anja Ruhdorfer
    Paracelsus Medical University, Salzburg, Austria
    Arthritis Rheumatol 68:826-36. 2016
    ..To investigate whether a clinically relevant change in knee function in patients with or at risk for osteoarthritis (OA) of the knee is associated with concurrent or prior change in thigh muscle strength...
  30. doi Contralateral knee effect on self-reported knee-specific function and global functional assessment: data from the Osteoarthritis Initiative
    Sebastian Cotofana
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria Chondrometrics GmbH, Ainring, Germany
    Arthritis Care Res (Hoboken) 67:374-81. 2015
    ..To analyze the effect of contralateral knee pain on sensitivity of patient-reported outcomes and objectively measured functional performance tests in subjects with knee osteoarthritis (OA)...
  31. pmc Relationship between isometric thigh muscle strength and minimum clinically important differences in knee function in osteoarthritis: data from the osteoarthritis initiative
    Anja Ruhdorfer
    Institute of Anatomy, Paracelsus Medical University, Salzburg and Nuremberg, Salzburg, Austria
    Arthritis Care Res (Hoboken) 67:509-18. 2015
    ..To determine the relationship between thigh muscle strength and clinically relevant differences in self-assessed lower leg function...
  32. doi Effect of exercise intervention on thigh muscle volume and anatomical cross-sectional areas--quantitative assessment using MRI
    Martin Hudelmaier
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Magn Reson Med 64:1713-20. 2010
    ..The study shows that MRI can be used to monitor location-specific effects of exercise intervention on muscle cross-sectional areas, with the proximal aspect of the thigh muscles being most responsive...
  33. pmc Segmentation of the lateral femoral notch sign with MRI using a new measurement technique
    Thomas Hoffelner
    Department of Traumatology, Sports Injuries of the Paracelsus Medical University, Salzburg, Austria
    BMC Musculoskelet Disord 16:217. 2015
    ..The goal of this present study was to precisely determine the dimension and location of the impaction fracture on the lateral femoral condyle in patients with an ACL rupture...
  34. pmc Quantitative cartilage imaging in knee osteoarthritis
    Felix Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Struberga β e 21, 5020 Salzburg, Austria
    Arthritis 2011:475684. 2011
    ....