Bernhard Watzl

Summary

Country: Germany

Publications

  1. doi request reprint Anti-inflammatory effects of plant-based foods and of their constituents
    Bernhard Watzl
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institute, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
    Int J Vitam Nutr Res 78:293-8. 2008
  2. doi request reprint No effect of the farming system (organic/conventional) on the bioavailability of apple (Malus domestica Bork., cultivar Golden Delicious) polyphenols in healthy men: a comparative study
    Berenike A Stracke
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institute, Federal Research Institute of Nutrition and Food, Haid und Neu Str 9, 76131, Karlsruhe, Germany
    Eur J Nutr 49:301-10. 2010
  3. doi request reprint No differences in DNA damage and antioxidant capacity between intervention groups of healthy, nonsmoking men receiving 2, 5, or 8 servings/day of vegetables and fruit
    Karlis Briviba
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Nutr Cancer 60:164-70. 2008
  4. doi request reprint Prevention of colon carcinogenesis by apple juice in vivo: impact of juice constituents and obesity
    Tatiana C L Koch
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institute, Karlsruhe, Germany
    Mol Nutr Food Res 53:1289-302. 2009
  5. doi request reprint Bioavailability and nutritional effects of carotenoids from organically and conventionally produced carrots in healthy men
    Berenike A Stracke
    Institute of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Federal Research Institute of Nutrition and Food, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    Br J Nutr 101:1664-72. 2009
  6. ncbi request reprint Moderate effects of apple juice consumption on obesity-related markers in obese men: impact of diet-gene interaction on body fat content
    Stephan W Barth
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Haid und Neu Strasse 9, 76131, Karlsruhe, Germany
    Eur J Nutr 51:841-50. 2012
  7. ncbi request reprint A 4-wk intervention with high intake of carotenoid-rich vegetables and fruit reduces plasma C-reactive protein in healthy, nonsmoking men
    Bernhard Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Am J Clin Nutr 82:1052-8. 2005
  8. ncbi request reprint A half-marathon and a marathon run induce oxidative DNA damage, reduce antioxidant capacity to protect DNA against damage and modify immune function in hobby runners
    Karlis Briviba
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Redox Rep 10:325-31. 2005
  9. doi request reprint Anthocyanin-rich juice does not affect gut-associated immunity in Fischer rats
    Daniela Graf
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
    Mol Nutr Food Res 57:1753-61. 2013
  10. doi request reprint Probiotic Lactobacillus casei Shirota supplementation does not modulate immunity in healthy men with reduced natural killer cell activity
    Stephanie Seifert
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Federal Research Institute of Nutrition and Food, Karlsruhe 76131, Germany
    J Nutr 141:978-84. 2011

Collaborators

Detail Information

Publications29

  1. doi request reprint Anti-inflammatory effects of plant-based foods and of their constituents
    Bernhard Watzl
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institute, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
    Int J Vitam Nutr Res 78:293-8. 2008
    ..A high intake of vegetables, fruit, and whole wheat as recommended by all international nutrition authorities provides a wide spectrum of bioactive compounds at health-promoting concentrations...
  2. doi request reprint No effect of the farming system (organic/conventional) on the bioavailability of apple (Malus domestica Bork., cultivar Golden Delicious) polyphenols in healthy men: a comparative study
    Berenike A Stracke
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institute, Federal Research Institute of Nutrition and Food, Haid und Neu Str 9, 76131, Karlsruhe, Germany
    Eur J Nutr 49:301-10. 2010
    ..However, data on the bioavailability of phytochemicals from organically or conventionally produced plant foods are scarce...
  3. doi request reprint No differences in DNA damage and antioxidant capacity between intervention groups of healthy, nonsmoking men receiving 2, 5, or 8 servings/day of vegetables and fruit
    Karlis Briviba
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Nutr Cancer 60:164-70. 2008
    ....
  4. doi request reprint Prevention of colon carcinogenesis by apple juice in vivo: impact of juice constituents and obesity
    Tatiana C L Koch
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institute, Karlsruhe, Germany
    Mol Nutr Food Res 53:1289-302. 2009
    ....
  5. doi request reprint Bioavailability and nutritional effects of carotenoids from organically and conventionally produced carrots in healthy men
    Berenike A Stracke
    Institute of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Federal Research Institute of Nutrition and Food, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    Br J Nutr 101:1664-72. 2009
    ....
  6. ncbi request reprint Moderate effects of apple juice consumption on obesity-related markers in obese men: impact of diet-gene interaction on body fat content
    Stephan W Barth
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Haid und Neu Strasse 9, 76131, Karlsruhe, Germany
    Eur J Nutr 51:841-50. 2012
    ....
  7. ncbi request reprint A 4-wk intervention with high intake of carotenoid-rich vegetables and fruit reduces plasma C-reactive protein in healthy, nonsmoking men
    Bernhard Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Am J Clin Nutr 82:1052-8. 2005
    ..Whether different intakes of vegetables and fruit modulate immunologic markers is currently not known...
  8. ncbi request reprint A half-marathon and a marathon run induce oxidative DNA damage, reduce antioxidant capacity to protect DNA against damage and modify immune function in hobby runners
    Karlis Briviba
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Redox Rep 10:325-31. 2005
    ....
  9. doi request reprint Anthocyanin-rich juice does not affect gut-associated immunity in Fischer rats
    Daniela Graf
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
    Mol Nutr Food Res 57:1753-61. 2013
    ..Therefore, the present study investigated the immunomodulatory effects of an anthocyanin-rich grape-bilberry juice (ARJ) on the systemic immune system, GALT, and mesenteric adipose tissue (MAT)...
  10. doi request reprint Probiotic Lactobacillus casei Shirota supplementation does not modulate immunity in healthy men with reduced natural killer cell activity
    Stephanie Seifert
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Federal Research Institute of Nutrition and Food, Karlsruhe 76131, Germany
    J Nutr 141:978-84. 2011
    ..However, other doses of LcS, time of intervention, or differences, e.g. in the background diet, may result in a different outcome...
  11. doi request reprint Influence of the production method on phytochemical concentrations in whole wheat (Triticum aestivum L.): a comparative study
    Berenike A Stracke
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institute, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
    J Agric Food Chem 57:10116-21. 2009
    ..Taken together, these results indicate that climate factors have a greater impact on the phytochemical concentrations in whole wheat than the production method (organic/conventional)...
  12. doi request reprint Differential Effect of Lactobacillus johnsonii BFE 6128 on Expression of Genes Related to TLR Pathways and Innate Immunity in Intestinal Epithelial Cells
    Stephanie Seifert
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Federal Research Institute for Nutrition and Food, Haid und Neu Strasse 9, 76131, Karlsruhe, Germany
    Probiotics Antimicrob Proteins 2:211-7. 2010
    ..Thus, the modulation of pro-inflammatory mediators and TLR-pathway-related molecules may be an important mechanism contributing to the potential stimulation of innate immunity by lactobacilli at the intestinal epithelial level. ..
  13. doi request reprint Dietary fat quality in regular fat diets has minor effects on biomarkers of inflammation in obese Zucker rats
    Daniela Graf
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Federal Research Institute of Nutrition and Food, 76131, Karlsruhe, Germany
    Eur J Nutr 53:211-9. 2014
    ..The aim of this study was to investigate, whether diets with regular fat contents but variable fat qualities affect adipose tissue-associated inflammation through the fatty acid composition of mesenteric adipose tissue (MAT)...
  14. doi request reprint Obesity-related promotion of aberrant crypt foci in DMH-treated obese Zucker rats correlates with dyslipidemia rather than hyperinsulinemia
    Tatiana C L Koch
    Department of Nutritional Physiology and Biochemistry, Max Rubner Institute, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    Eur J Nutr 47:161-70. 2008
    ..Obesity and energy restriction modulate the development of precancerous aberrant crypt foci (ACF) in animal models of colon cancer...
  15. ncbi request reprint Paraoxonase 1 Q192R (PON1-192) polymorphism is associated with reduced lipid peroxidation in healthy young men on a low-carotenoid diet supplemented with tomato juice
    Achim Bub
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Haid und Neu Str 9, Karlsruhe, Germany
    Br J Nutr 93:291-7. 2005
    ....
  16. doi request reprint Isoflavone supplementation in postmenopausal women does not affect leukocyte LDL receptor and scavenger receptor CD36 expression: A double-blind, randomized, placebo-controlled trial
    Ann Katrin Engelbert
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
    Mol Nutr Food Res 60:2008-19. 2016
    ..We investigated the impact of isoflavones on the receptor expression of both receptors in leukocytes of PMW...
  17. pmc The Karlsruhe Metabolomics and Nutrition (KarMeN) Study: Protocol and Methods of a Cross-Sectional Study to Characterize the Metabolome of Healthy Men and Women
    Achim Bub
    Max Rubner Institut, Department of Physiology and Biochemistry of Nutrition, Karlsruhe, Germany
    JMIR Res Protoc 5:e146. 2016
    ....
  18. doi request reprint Three-year comparison of the polyphenol contents and antioxidant capacities in organically and conventionally produced apples ( Malus domestica Bork. Cultivar 'Golden Delicious')
    Berenike A Stracke
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institute, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
    J Agric Food Chem 57:4598-605. 2009
    ..Overall, the production method had a smaller impact on the variation in the polyphenol content and antioxidant capacity of apples than the yearly climate...
  19. doi request reprint Phytoestrogens and phytoestrogen metabolites differentially modulate immune parameters in human leukocytes
    Sandra Gredel
    Max Rubner Institute, Federal Research Institute for Nutrition and Food, Department of Physiology and Biochemistry of Nutrition, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    Food Chem Toxicol 46:3691-6. 2008
    ..In conclusion, while physiological concentrations of isoflavones have minor effects on cytokine secretion, lignans including their major metabolites do not modulate human leukocyte functions in vitro...
  20. doi request reprint Phase II metabolism of the soy isoflavones genistein and daidzein in humans, rats and mice: a cross-species and sex comparison
    Sebastian T Soukup
    Department of Safety and Quality of Fruit and Vegetables, Max Rubner Institut, Haid und Neu Straße 9, 76131, Karlsruhe, Germany
    Arch Toxicol 90:1335-47. 2016
    ..These differences may contribute to resolve inconsistencies in results concerning the bioactivity of IF and should be considered when applying findings of animal studies to humans, e.g., for risk assessment. ..
  21. pmc Age-Related Changes of Plasma Bile Acid Concentrations in Healthy Adults--Results from the Cross-Sectional KarMeN Study
    Lara Frommherz
    Department of Safety and Quality of Fruit and Vegetables, Max Rubner Institut, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
    PLoS ONE 11:e0153959. 2016
    ..We conclude that age and sex are associated with the fasting plasma concentrations. Those associations are significant and need to be considered in studies investigating the role of BA in the human metabolism. ..
  22. doi request reprint Influence of a probiotic Lactobacillus casei strain on the colonisation with potential pathogenic streptococci and Staphylococcus aureus in the nasopharyngeal space of healthy men with a low baseline NK cell activity
    Charles M A P Franz
    Department of Safety and Quality of Fruit and Vegetables, Max Rubner Institut, Federal Research Institute for Nutrition and Food, Haid und Neu Straße 9, 76131, Karlsruhe, Germany
    Med Microbiol Immunol 204:527-38. 2015
    ..Thus, the intervention did not influence the nasopharyngeal colonisation with Gram-positive potential pathogens. Production of salivary SIgA as a potential means of microbiota modulation was also not affected. ..
  23. doi request reprint Application of the BRAFO-tiered approach for benefit-risk assessment to case studies on natural foods
    Bernhard Watzl
    Max Rubner Institute, Federal Research Institute for Nutrition and Food, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    Food Chem Toxicol 50:S699-709. 2012
    ..We conclude that the BRAFO methodology is highly applicable to natural foods. It will help the benefit-risk managers in selecting the appropriate dietary recommendations for the population...
  24. doi request reprint In vivo bioassay to detect irinotecan-stabilized DNA/topoisomerase I complexes in rats
    Stephan W Barth
    Department of Nutrition Physiology and Biochemistry, Max Rubner Institute, Karlsruhe, Germany
    Biotechnol J 5:321-7. 2010
    ..The ICE bioassay and the comet assay represent two test systems for investigating the impact of topoisomerase I poisons on DNA integrity in colon tissues of Wistar rats...
  25. pmc Influence of Freezing and Storage Procedure on Human Urine Samples in NMR-Based Metabolomics
    Manuela J Rist
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut MRI, Haid und Neu Str 9, Karlsruhe 76131, Germany
    Metabolites 3:243-58. 2013
    ..Thus, we recommend that urine samples should be frozen at -20 °C and transferred to lower storage temperatures within one week and that freezing procedures should be part of the publication protocol. ..
  26. doi request reprint Lactobacilli stimulate the innate immune response and modulate the TLR expression of HT29 intestinal epithelial cells in vitro
    Maria G Vizoso Pinto
    Department of Safety and Quality of Fruit and Vegetables, Federal Research Institute for Nutrition and Food, Karlsruhe, Germany
    Int J Food Microbiol 133:86-93. 2009
    ..These findings show that stimulation of specific signaling pathways occurs in the cross-talk between probiotic bacteria and gut epithelium cells, which can help to explain the adjuvant properties of probiotic lactobacilli...
  27. pmc Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells
    Anke Jaudszus
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut, Karlsruhe, Germany
    J Lipid Res 54:923-35. 2013
    ..Our results suggest that EPA and DHA do not generally affect immune cell functions in an inhibitory manner but rather promote pro-resolving responses...
  28. ncbi request reprint Effects of supplementing a low-carotenoid diet with a tomato extract for 2 weeks on endogenous levels of DNA single strand breaks and immune functions in healthy non-smokers and smokers
    Karlis Briviba
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Carcinogenesis 25:2373-8. 2004
    ..009)...