Jonas Waider

Summary

Country: Germany

Publications

  1. doi request reprint GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice
    Jonas Waider
    Laboratory of Translational Neuroscience, Division of Molecular Psychiatry, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080 Wuerzburg, Germany
    Histochem Cell Biol 139:267-81. 2013
  2. doi request reprint Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice
    Lise Gutknecht
    Molecular and Clinical Psychobiology, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080 Wuerzburg, Germany
    Eur Neuropsychopharmacol 19:266-82. 2009
  3. pmc Impacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification
    Lise Gutknecht
    Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany
    PLoS ONE 7:e43157. 2012
  4. pmc Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice
    Lise Gutknecht
    Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany
    Psychopharmacology (Berl) 232:2429-41. 2015
  5. pmc Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour
    Klaus Peter Lesch
    Division of Molecular Psychiatry MP, Laboratory of Translational Neuroscience LTN, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080 Wuerzburg, Germany
    Philos Trans R Soc Lond B Biol Sci 367:2426-43. 2012
  6. doi request reprint Tryptophan hydroxylase-2 (TPH2) in disorders of cognitive control and emotion regulation: a perspective
    Jonas Waider
    Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080 Wuerzburg, Germany
    Psychoneuroendocrinology 36:393-405. 2011
  7. doi request reprint Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice
    Lise Gutknecht
    Molecular and Clinical Psychobiology, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080, Wuerzburg, Germany
    J Neural Transm (Vienna) 115:1127-32. 2008
  8. doi request reprint Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders
    Klaus Peter Lesch
    Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, ADHD Clinical Research Network, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, 97080 Wurzburg, Germany
    Neuron 76:175-91. 2012

Detail Information

Publications8

  1. doi request reprint GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice
    Jonas Waider
    Laboratory of Translational Neuroscience, Division of Molecular Psychiatry, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080 Wuerzburg, Germany
    Histochem Cell Biol 139:267-81. 2013
    ..Taken together, our findings provide further insight into the mechanisms how life-long 5-HT deficiency impacts the pathogenesis of anxiety- and fear-related disorders...
  2. doi request reprint Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice
    Lise Gutknecht
    Molecular and Clinical Psychobiology, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080 Wuerzburg, Germany
    Eur Neuropsychopharmacol 19:266-82. 2009
    ..In conclusion, our findings indicate that brain 5-HT synthesis across the lifespan is exclusively maintained by TPH2...
  3. pmc Impacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification
    Lise Gutknecht
    Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany
    PLoS ONE 7:e43157. 2012
    ....
  4. pmc Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice
    Lise Gutknecht
    Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany
    Psychopharmacology (Berl) 232:2429-41. 2015
    ....
  5. pmc Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour
    Klaus Peter Lesch
    Division of Molecular Psychiatry MP, Laboratory of Translational Neuroscience LTN, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080 Wuerzburg, Germany
    Philos Trans R Soc Lond B Biol Sci 367:2426-43. 2012
    ..Mouse models in conjunction with approaches focusing on TPH2 variants in humans provide unexpected views of 5-HT's role in brain development and in disorders related to negative emotionality, aggression and antisocial behaviour...
  6. doi request reprint Tryptophan hydroxylase-2 (TPH2) in disorders of cognitive control and emotion regulation: a perspective
    Jonas Waider
    Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080 Wuerzburg, Germany
    Psychoneuroendocrinology 36:393-405. 2011
    ....
  7. doi request reprint Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice
    Lise Gutknecht
    Molecular and Clinical Psychobiology, Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080, Wuerzburg, Germany
    J Neural Transm (Vienna) 115:1127-32. 2008
    ..The findings confirm the exclusive specificity of Tph2 in brain 5-HT synthesis and suggest that Tph2-synthesized 5-HT is not required for serotonergic neuron formation...
  8. doi request reprint Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders
    Klaus Peter Lesch
    Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, ADHD Clinical Research Network, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, 97080 Wurzburg, Germany
    Neuron 76:175-91. 2012
    ....