Igor Yakushev

Summary

Affiliation: University of Mainz
Country: Germany

Publications

  1. doi request reprint Choice of reference area in studies of Alzheimer's disease using positron emission tomography with fluorodeoxyglucose-F18
    Igor Yakushev
    Department of Nuclear Medicine, University of Mainz, Mainz, Germany
    Psychiatry Res 164:143-53. 2008
  2. doi request reprint Dopamine D2/D3 receptor availability and venturesomeness
    Nina Bernow
    Department of Psychiatry and Psychotherapy, University of Mainz, Mainz, Germany
    Psychiatry Res 193:80-4. 2011
  3. doi request reprint Functional implications of hippocampal degeneration in early Alzheimer's disease: a combined DTI and PET study
    Igor Yakushev
    Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str 8, 55131 Mainz, Germany
    Eur J Nucl Med Mol Imaging 38:2219-27. 2011
  4. doi request reprint SPM-based count normalization provides excellent discrimination of mild Alzheimer's disease and amnestic mild cognitive impairment from healthy aging
    Igor Yakushev
    Department of Nuclear Medicine, University of Mainz, Mainz, Germany
    Neuroimage 44:43-50. 2009
  5. doi request reprint Association of low striatal dopamine d2 receptor availability with nicotine dependence similar to that seen with other drugs of abuse
    Christoph Fehr
    Department of Psychiatry, University of Mainz, Untere Zahlbacher Strasse 8, 55131 Mainz, Germany
    Am J Psychiatry 165:507-14. 2008
  6. doi request reprint Cerebrospinal fluid tau protein levels and 18F-fluorodeoxyglucose positron emission tomography in the differential diagnosis of Alzheimer's disease
    Igor Yakushev
    Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany
    Dement Geriatr Cogn Disord 30:245-53. 2010
  7. doi request reprint Functional representation of olfactory impairment in early Alzheimer's disease
    Stefan Forster
    Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
    J Alzheimers Dis 22:581-91. 2010
  8. doi request reprint Automated tractography of the cingulate bundle in Alzheimer's disease: a multicenter DTI study
    Florian U Fischer
    Department of Psychiatry, University Medical Center of Mainz, Mainz, Germany
    J Magn Reson Imaging 36:84-91. 2012
  9. doi request reprint FDG-PET mapping the brain substrates of visuo-constructive processing in Alzheimer's disease
    Stefan Forster
    Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
    J Psychiatr Res 44:462-9. 2010
  10. doi request reprint Increased hippocampal head diffusivity predicts impaired episodic memory performance in early Alzheimer's disease
    Igor Yakushev
    Department of Psychiatry and Psychotherapy, University of Mainz, Mainz, Germany
    Neuropsychologia 48:1447-53. 2010

Detail Information

Publications19

  1. doi request reprint Choice of reference area in studies of Alzheimer's disease using positron emission tomography with fluorodeoxyglucose-F18
    Igor Yakushev
    Department of Nuclear Medicine, University of Mainz, Mainz, Germany
    Psychiatry Res 164:143-53. 2008
    ..Normalization to CGM should be used with great caution not only in advanced stages of dementia, but also in very mild AD cases...
  2. doi request reprint Dopamine D2/D3 receptor availability and venturesomeness
    Nina Bernow
    Department of Psychiatry and Psychotherapy, University of Mainz, Mainz, Germany
    Psychiatry Res 193:80-4. 2011
    ..Our results suggest the involvement of extrastriatal dopaminergic neurotransmission in venturesomeness, a component of impulsivity...
  3. doi request reprint Functional implications of hippocampal degeneration in early Alzheimer's disease: a combined DTI and PET study
    Igor Yakushev
    Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str 8, 55131 Mainz, Germany
    Eur J Nucl Med Mol Imaging 38:2219-27. 2011
    ..Here, we explored the association between microstructural alterations within the hippocampus and whole-brain glucose metabolism in subjects with AD, also in relation to episodic memory impairment...
  4. doi request reprint SPM-based count normalization provides excellent discrimination of mild Alzheimer's disease and amnestic mild cognitive impairment from healthy aging
    Igor Yakushev
    Department of Nuclear Medicine, University of Mainz, Mainz, Germany
    Neuroimage 44:43-50. 2009
    ....
  5. doi request reprint Association of low striatal dopamine d2 receptor availability with nicotine dependence similar to that seen with other drugs of abuse
    Christoph Fehr
    Department of Psychiatry, University of Mainz, Untere Zahlbacher Strasse 8, 55131 Mainz, Germany
    Am J Psychiatry 165:507-14. 2008
    ..However, it is unclear whether similar changes can also be observed in heavy-smoking nicotine-dependent smokers...
  6. doi request reprint Cerebrospinal fluid tau protein levels and 18F-fluorodeoxyglucose positron emission tomography in the differential diagnosis of Alzheimer's disease
    Igor Yakushev
    Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany
    Dement Geriatr Cogn Disord 30:245-53. 2010
    ....
  7. doi request reprint Functional representation of olfactory impairment in early Alzheimer's disease
    Stefan Forster
    Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
    J Alzheimers Dis 22:581-91. 2010
    ....
  8. doi request reprint Automated tractography of the cingulate bundle in Alzheimer's disease: a multicenter DTI study
    Florian U Fischer
    Department of Psychiatry, University Medical Center of Mainz, Mainz, Germany
    J Magn Reson Imaging 36:84-91. 2012
    ..To evaluate the feasibility of multicenter tractography of the cingulate bundle (CB) in Alzheimer's disease (AD)...
  9. doi request reprint FDG-PET mapping the brain substrates of visuo-constructive processing in Alzheimer's disease
    Stefan Forster
    Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
    J Psychiatr Res 44:462-9. 2010
    ..From a clinical point of view, both of these widely used visual tests evaluate the integrity of complementary cortical networks and may contribute complementary information on the integrity of visual processing in AD...
  10. doi request reprint Increased hippocampal head diffusivity predicts impaired episodic memory performance in early Alzheimer's disease
    Igor Yakushev
    Department of Psychiatry and Psychotherapy, University of Mainz, Mainz, Germany
    Neuropsychologia 48:1447-53. 2010
    ..Diffusivity measurements might be highly sensitive to functionally relevant degenerative alterations of the hippocampus...
  11. ncbi request reprint Tiagabine does not attenuate alcohol-induced activation of the human reward system
    Christoph Fehr
    Department of Psychiatry, University of Mainz, Untere Zahlbacher Strasse 8, 55131, Mainz, Germany
    Psychopharmacology (Berl) 191:975-83. 2007
    ....
  12. doi request reprint Structural integrity of the corpus callosum predicts long-term transfer of fluid intelligence-related training gains in normal aging
    Dominik Wolf
    Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str 8, Mainz, Germany
    Hum Brain Mapp 35:309-18. 2014
    ..Further studies are needed to reveal the interaction of transfer, age, and structural integrity and delineate mechanisms of age-dependent transfer capabilities...
  13. doi request reprint Metabolic and structural connectivity within the default mode network relates to working memory performance in young healthy adults
    Igor Yakushev
    Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany
    Neuroimage 79:184-90. 2013
    ..Metabolic connectivity as quantified with FDG-PET might be a sensitive marker of the normal variability in some cognitive functions...
  14. doi request reprint Diffusion tensor imaging of the hippocampus in MCI and early Alzheimer's disease
    Andreas Fellgiebel
    Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany
    J Alzheimers Dis 26:257-62. 2011
    ..Development of automatic algorithms, providing MD measurements of the hippocampus for routine use, is a task for future studies...
  15. doi request reprint Relationships between hippocampal microstructure, metabolism, and function in early Alzheimer's disease
    Igor Yakushev
    Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str 8, 55131 Mainz, Germany
    Brain Struct Funct 216:219-26. 2011
    ..This neurobiological distinction of the anterior hippocampus might be related to the disruption of the perforant pathway that is known to occur early in the course of AD...
  16. ncbi request reprint Decreased dopamine D2/D3-receptor binding in temporal lobe epilepsy: an [18F]fallypride PET study
    Konrad J Werhahn
    Department of Neurology, Johannes Gutenberg University, Rhineland Palatinate, Germany
    Epilepsia 47:1392-6. 2006
    ..Although animal data are suggestive, evidence for an alteration of the extrastriatal dopaminergic system in human focal epilepsy is missing...
  17. ncbi request reprint Metabolic connectivity for differential diagnosis of dementing disorders
    Dmitry Titov
    Department of Nuclear Medicine, Technische Universitat Munchen, Munich, Germany
    J Cereb Blood Flow Metab 37:252-262. 2017
    ..Such patterns can be utilized for single-subject analyses and might be more accurate in the differential diagnosis of dementing disorders than traditional intensity-based analyses...
  18. doi request reprint Prefrontal hypometabolism in Alzheimer disease is related to longitudinal amyloid accumulation in remote brain regions
    Elisabeth Klupp
    Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Nucl Med 56:399-404. 2015
    ....
  19. doi request reprint Basilar artery diameter is a potential screening tool for Fabry disease in young stroke patients
    Andreas Fellgiebel
    Department of Psychiatry, University of Mainz, Untere Zahlbacher Strasse 8, Mainz, Germany
    Cerebrovasc Dis 31:294-9. 2011
    ..The aim of this study was to compare BADs of young stroke patients without FD to those of FD patients and of healthy age-matched controls...