Martin Wagner

Summary

Affiliation: University of Ulm
Country: Germany

Publications

  1. doi request reprint Selective expansion of the beta-cell compartment in the pancreas of keratinocyte growth factor transgenic mice
    Martin Wagner
    Department of Internal Medicine I, University Ulm, Germany
    Am J Physiol Gastrointest Liver Physiol 294:G1139-47. 2008
  2. ncbi request reprint Pancreatic stellate cells potentiate proinvasive effects of SERPINE2 expression in pancreatic cancer xenograft tumors
    Albrecht Neesse
    Department of Internal Medicine I, University Hospital of Ulm, Ulm, Germany
    Pancreatology 7:380-5. 2007
  3. pmc Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway
    Malte Buchholz
    Translational Genome Research Group, Department of Internal Medicine I, University of Ulm, Ulm, Germany
    EMBO J 25:3714-24. 2006
  4. ncbi request reprint The tumor suppressor KLF11 mediates a novel mechanism in transforming growth factor beta-induced growth inhibition that is inactivated in pancreatic cancer
    Anita Buck
    Department of Internal Medicine I, University of Ulm, Germany
    Mol Cancer Res 4:861-72. 2006
  5. doi request reprint Inflammation, regeneration, and transformation in the pancreas: results of the Collaborative Research Center 518 (SFB 518) at the University of Ulm
    Klaudia Giehl
    Department of Internal Medicine I, Center for Internal Medicine, University of Ulm, Germany
    Pancreas 40:489-502. 2011
  6. ncbi request reprint Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells
    Martin Wagner
    Department of Internal Medicine I, University of Ulm, Germany
    Gastroenterology 122:1898-912. 2002
  7. ncbi request reprint Transgenic overexpression of the oncofetal RNA binding protein KOC leads to remodeling of the exocrine pancreas
    Martin Wagner
    Department of Internal Medicine I, University of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Gastroenterology 124:1901-14. 2003
  8. ncbi request reprint Evaluation of pyrimidine metabolising enzymes and in vitro uptake of 3'-[(18)F]fluoro-3'-deoxythymidine ([(18)F]FLT) in pancreatic cancer cell lines
    Ulrike Seitz
    Department of Nuclear Medicine, University of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Eur J Nucl Med Mol Imaging 29:1174-81. 2002
  9. doi request reprint Strongyloides stercoralis: a rare cause of obstructive duodenal stenosis
    Markus S Juchems
    Diagnostic and Interventional Radiology, University Hospitals Ulm, Ulm, Germany
    Digestion 77:141-4. 2008
  10. pmc Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis
    Mariia Lunova
    Department of Internal Medicine I, University Medical Center Ulm, Ulm, Germany
    PLoS ONE 7:e39972. 2012

Collaborators

Detail Information

Publications50

  1. doi request reprint Selective expansion of the beta-cell compartment in the pancreas of keratinocyte growth factor transgenic mice
    Martin Wagner
    Department of Internal Medicine I, University Ulm, Germany
    Am J Physiol Gastrointest Liver Physiol 294:G1139-47. 2008
    ..Furthermore, the observed phenotype demonstrates that an increase in the beta-cell compartment does not necessarily result in an improved glucose tolerance in vivo...
  2. ncbi request reprint Pancreatic stellate cells potentiate proinvasive effects of SERPINE2 expression in pancreatic cancer xenograft tumors
    Albrecht Neesse
    Department of Internal Medicine I, University Hospital of Ulm, Ulm, Germany
    Pancreatology 7:380-5. 2007
    ..Our data thus suggest that SERPINE2 is an important modulator of tumor cell/host interactions in pancreatic cancer...
  3. pmc Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway
    Malte Buchholz
    Translational Genome Research Group, Department of Internal Medicine I, University of Ulm, Ulm, Germany
    EMBO J 25:3714-24. 2006
    ..Together, these results demonstrate that ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway is an important mechanism of oncogenic c-myc activation in pancreatic cancer...
  4. ncbi request reprint The tumor suppressor KLF11 mediates a novel mechanism in transforming growth factor beta-induced growth inhibition that is inactivated in pancreatic cancer
    Anita Buck
    Department of Internal Medicine I, University of Ulm, Germany
    Mol Cancer Res 4:861-72. 2006
    ....
  5. doi request reprint Inflammation, regeneration, and transformation in the pancreas: results of the Collaborative Research Center 518 (SFB 518) at the University of Ulm
    Klaudia Giehl
    Department of Internal Medicine I, Center for Internal Medicine, University of Ulm, Germany
    Pancreas 40:489-502. 2011
    ....
  6. ncbi request reprint Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells
    Martin Wagner
    Department of Internal Medicine I, University of Ulm, Germany
    Gastroenterology 122:1898-912. 2002
    ....
  7. ncbi request reprint Transgenic overexpression of the oncofetal RNA binding protein KOC leads to remodeling of the exocrine pancreas
    Martin Wagner
    Department of Internal Medicine I, University of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Gastroenterology 124:1901-14. 2003
    ..To elucidate the function of the oncofetal RNA-binding protein, K-homologous (KH) domain containing protein overexpressed in cancer (KOC), we studied the effect of a constitutive reexpression of KOC in transgenic mice...
  8. ncbi request reprint Evaluation of pyrimidine metabolising enzymes and in vitro uptake of 3'-[(18)F]fluoro-3'-deoxythymidine ([(18)F]FLT) in pancreatic cancer cell lines
    Ulrike Seitz
    Department of Nuclear Medicine, University of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Eur J Nucl Med Mol Imaging 29:1174-81. 2002
    ..Thus, we propose [(18)F]FLT as a promising tracer for positron emission tomography that might overcome current limitations in the diagnosis of pancreatic cancer...
  9. doi request reprint Strongyloides stercoralis: a rare cause of obstructive duodenal stenosis
    Markus S Juchems
    Diagnostic and Interventional Radiology, University Hospitals Ulm, Ulm, Germany
    Digestion 77:141-4. 2008
    ..Strongyloidiasis is a rare helminthic infection in Europe, and it may cause duodenal obstruction...
  10. pmc Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis
    Mariia Lunova
    Department of Internal Medicine I, University Medical Center Ulm, Ulm, Germany
    PLoS ONE 7:e39972. 2012
    ..Increased Hsp72 levels were implicated in protection from acute pancreatitis; a hypothesis which was not tested in a transgenic mouse model yet...
  11. ncbi request reprint SERPINE2 (protease nexin I) promotes extracellular matrix production and local invasion of pancreatic tumors in vivo
    Malte Buchholz
    Department of Internal Medicine I, University Medical Center, University of Ulm, 89081 Ulm, Germany
    Cancer Res 63:4945-51. 2003
    ..Thus, our experimental system for the first time provides the opportunity to effectively model the desmoplastic reaction of pancreatic cancer and represents a valuable new tool for the study of tumor-stroma interactions...
  12. doi request reprint Loss of Lsc/p115 protein leads to neuronal hypoplasia in the esophagus and an achalasia-like phenotype in mice
    Eugen Zizer
    Department of Internal Medicine I, Center of Internal Medicine, University Ulm, Ulm, Germany
    Gastroenterology 139:1344-54. 2010
    ..Here we investigate the expression pattern of lsc/p115 in the gastrointestinal tract and the consequences of lsc/p115 deficiency in lsc/p115-knockout mice...
  13. pmc Cellular immune reaction in the pancreas is induced by constitutively active IkappaB kinase-2
    Tamara Aleksic
    Department of Medicine I, Ulm University, Robert Koch Strasse 8, D 89081 Ulm, Germany
    Gut 56:227-36. 2007
    ..Little is known of the individual roles of these proteins in organ specific inflammation. The aim of the present study was to analyse the consequences of ectopic IkappaB kinase-2 (IKK2) activation in the pancreas of mice...
  14. ncbi request reprint Overexpression of ErbB2 in the exocrine pancreas induces an inflammatory response but not increased proliferation
    Hana Algül
    II Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munchen, Germany
    Int J Cancer 121:1410-6. 2007
    ..We conclude that the biological response of ErbB2/RAS signaling depends highly on cellular context...
  15. ncbi request reprint 3'-[18F]fluoro-3'-deoxythymidine ([18F]-FLT) as positron emission tomography tracer for imaging proliferation in a murine B-Cell lymphoma model and in the human disease
    Martin Wagner
    Department of Nuclear Medicine, University of Ulm, 89081 Ulm, Germany
    Cancer Res 63:2681-7. 2003
    ..These results suggest that [(18)F]-FLT represents a novel tracer for PET that enables imaging of proliferation in human lymphoma in vivo...
  16. ncbi request reprint Hepatobiliary transporter expression in intercellular adhesion molecule 1 knockout and Fas receptor-deficient mice after common bile duct ligation is independent of the degree of inflammation and oxidative stress
    Martin Wagner
    Laboratory of Experimental and Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Medicine, Medical University Graz, Auenbruggerplatz 15, A 8036 Graz, Austria
    Drug Metab Dispos 35:1694-9. 2007
    ..Induction of the adaptive transporter response after CBDL is independent of the degree of the inflammatory response. Rather, retention of biliary constituents may determine transporter expression in CBDL...
  17. ncbi request reprint Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer
    Susanne Liptay
    Department of Pediatrics, University of Ulm, Ulm, Germany
    Int J Cancer 105:735-46. 2003
    ..Inhibition of NF-kappaB/Rel activity reveals a mitogenic and antiapoptotic role for NF-kappaB/Rel in pancreatic cancer...
  18. ncbi request reprint Stat3 and NF-kappaB activation prevents apoptosis in pancreatic carcinogenesis
    Florian R Greten
    Internal Medicine II, Technical University of Munich, Germany
    Gastroenterology 123:2052-63. 2002
    ..The aim of the present study was to explore regulation of proapoptotic and antiapoptotic signals during pancreatic tumor development in mice...
  19. pmc Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells
    Przemyslaw Blyszczuk
    In Vitro Differentiation Group, Institute of Plant Genetics and Crop Plant Research, D 06466 Gatersleben, Germany
    Proc Natl Acad Sci U S A 100:998-1003. 2003
    ....
  20. ncbi request reprint CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness
    Patrick Michl
    Signal Transduction Laboratory, Cancer Research UK London Research Institute, 44 Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
    Cancer Cell 7:521-32. 2005
    ..This suggests that CUTL1 plays a central role in coordinating a gene expression program associated with cell motility and tumor progression...
  21. ncbi request reprint Ethidium monoazide and propidium monoazide for elimination of unspecific DNA background in quantitative universal real-time PCR
    Ingeborg Hein
    Institute of Milk Hygiene, Milk Technology and Food Science, Department of Veterinary Public Health and Food Science, University of Veterinary Medicine, Veterinaerplatz 1, A 1210 Vienna, Austria
    J Microbiol Methods 71:336-9. 2007
    ..The proposed procedure had no effect on the sensitivity of the real-time PCR reaction...
  22. pmc Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice
    Peter Fickert
    Laboratory of Experimental and Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University Graz, Auenbruggerplatz 15, A 8036 Graz, Austria
    Am J Pathol 168:410-22. 2006
    ..Thus, we demonstrate that LCA feeding in mice leads to segmental bile duct obstruction, destructive cholangitis, periductal fibrosis, and an adaptive transporter and metabolic enzyme response...
  23. ncbi request reprint Inhibitor-free DNA for real-time PCR analysis of synovial fluid from horses, cattle and pigs
    Wilfried Schneeweiss
    Clinic for Orthopaedics in Ungulates, Department for Small Animals and Horses, University of Veterinary Medicine, Veterinaerplatz 1, A 1210 Vienna, Austria
    Vet Microbiol 121:189-93. 2007
    ..When analyzing non-pelleted synovial fluid, three kits - two based on silica columns and one employing a desalting process - yielded inhibitor-free DNA for real-time PCR analysis...
  24. ncbi request reprint Analysis of apoptosome dysregulation in pancreatic cancer and of its role in chemoresistance
    Marco Corvaro
    Dulbecco Telethon Institute, Department of Biology, University of Tor Vergata, Via della Ricerca Scientifica, Rome 00133, Italy
    Cancer Biol Ther 6:209-17. 2007
    ..In addition, we restored APAF1 and Caspase-9 dosage in Panc-1 cells, where the apoptosome is downregulated, by overexpressing the murine cDNA of the two molecules, and we improved the death response to chemotherapeutic agents...
  25. ncbi request reprint MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes
    Michael Trauner
    Laboratory of Experimental and Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Austria
    Semin Liver Dis 27:77-98. 2007
    ..Several drugs for the treatment of cholestatic liver diseases target MDR3 expression and function, further underscoring the clinical significance of this transport system...
  26. ncbi request reprint Real-time PCR method with statistical analysis to compare the potential of DNA isolation methods to remove PCR inhibitors from samples for diagnostic PCR
    Gabriele Flekna
    Department of Veterinary Public Health and Food Science, University of Veterinary Medicine, Veterinarplatz 1, A 1210 Vienna, Austria
    Mol Cell Probes 21:282-7. 2007
    ....
  27. ncbi request reprint Insufficient differentiation of live and dead Campylobacter jejuni and Listeria monocytogenes cells by ethidium monoazide (EMA) compromises EMA/real-time PCR
    Gabriele Flekna
    Institute of Meat Hygiene, Meat Technology and Food Science, Department of Veterinary Public Health and Food Science, University of Veterinary Medicine, Veterinarplatz 1, 1210 Vienna, Austria
    Res Microbiol 158:405-12. 2007
    ..The results suggest that EMA influences not only dead but also viable cells of C. jejuni and L. monocytogenes. Thus EMA/real-time PCR is a poor indicator of cell viability...
  28. pmc Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo
    Bernd Baumann
    Institute of Physiological Chemistry, University of Ulm, Ulm, Germany
    J Clin Invest 117:1502-13. 2007
    ..Our data identify the IKK/NF-kappaB pathway in acinar cells as being key to the development of experimental pancreatitis and the major factor in the inflammatory response typical of this disease...
  29. doi request reprint The cAMP/Epac1/Rap1 pathway in pancreatic carcinoma
    Richard Lorenz
    Pancreas 37:102-3. 2008
  30. ncbi request reprint Development of matrix lysis for concentration of gram positive bacteria from food and blood
    Peter Rossmanith
    Institute of Milk Hygiene, Milk Technology and Food Science, Department of Veterinary Public Health and Food Science, University of Veterinary Medicine, Veterinarplatz 1, 1210 Vienna, Austria
    J Microbiol Methods 69:504-11. 2007
    ..Using real-time PCR, 7.3 CFU of L. monocytogenes were detected in artificially contaminated ultra-high temperature treated (UHT) milk and raw milk...
  31. pmc Enumeration of salmonella bacteria in food and feed samples by real-time PCR for quantitative microbial risk assessment
    Burkhard Malorny
    Federal Institute for Risk Assessment, National Salmonella Reference Laboratory, Diedersdorfer Weg 1, D 12277 Berlin, Germany
    Appl Environ Microbiol 74:1299-304. 2008
  32. ncbi request reprint Detection of Listeria monocytogenes in food using a combined enrichment/real-time PCR method targeting the prfA gene
    Peter Rossmanith
    Institute of Milk Hygiene, Milk Technology, and Food Science, Department of Veterinary Public Health and Food Science, University of Veterinary Medicine, Veterinarplatz 1, 1210 Vienna, Austria
    Res Microbiol 157:763-71. 2006
    ..When analyzing 76 naturally contaminated food samples of various types and comparing the results with the ISO 11290-1 standard method, the relative accuracy was 96%, the relative specificity 100%, and the relative sensitivity, 76.9%...
  33. ncbi request reprint Nucleic acid-based, cultivation-independent detection of Listeria spp and genotypes of L monocytogenes
    Michael Schmid
    Lehrstuhl fur Mikrobiologie, Technische Universitat Munchen, Am Hochanger 4, 85354 Freising, Germany
    FEMS Immunol Med Microbiol 35:215-25. 2003
    ..The amplification of non-specific PCR products from DNA of non-target strains was prevented by adding competitive primers. By applying this method, the rapid and reliable distinction of the three L. monocytogenes genotypes was possible...
  34. ncbi request reprint Physical characteristics of six new thermocyclers
    Dagmar Schoder
    Institute for Milk Hygiene, Milk Technology and Food Science, Veterinarplatz 1, 1210 Vienna, Austria
    Clin Chem 49:960-3. 2003
  35. ncbi request reprint Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice
    Martin Wagner
    Department of Medicine, Karl Franzens University, Graz, Austria
    Gastroenterology 125:825-38. 2003
    ..We aimed to investigate the role of the nuclear bile acid receptor (farnesoid X receptor [FXR]) in mediating changes in ABC transporter expression and in determining liver injury...
  36. ncbi request reprint Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine
    Gernot Zollner
    Division of Gastroenterology and Hepatology, Department of Medicine, Karl Franzens University, Auenbruggerplatz 15, A 8036 Graz, Austria
    J Hepatol 39:480-8. 2003
    ..Whether adaptive changes in ATP-binding cassette (ABC) transporter expression are stimulated by bile acids and their nuclear receptor FXR is unknown...
  37. pmc Making internal amplification control mandatory for diagnostic PCR
    Jeffrey Hoorfar
    J Clin Microbiol 41:5835. 2003
  38. ncbi request reprint Oxidized LDL induces proliferation and hypertrophy in human umbilical vein endothelial cells via regulation of p27Kip1 expression: role of RhoA
    Stefan Seibold
    Department of Medicine, University Hospital Wurzburg, Joseph Schneider Strasse 2, D 97080 Wurzburg, Germany
    J Am Soc Nephrol 15:3026-34. 2004
    ..OxLDL may importantly contribute to vascular hyperplasia in atherosclerosis and other diseases associated with increased levels of OxLDL...
  39. pmc The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization
    Irute Girkontaite
    Department of Physiological Chemistry, University of Ulm, Albert Einstein Allee 11, D 89069 Ulm, Germany
    J Exp Med 200:1491-501. 2004
    ..These data identify lysophospholipids and the S1P(3) receptor as essential regulators of the MZ sinus and its role as a barrier to the follicle...
  40. ncbi request reprint Hepatobiliary transporter expression in human hepatocellular carcinoma
    Gernot Zollner
    Division of Gastroenterology and Hepatology, Department of Medicine, Medical University, Auenbruggerplatz 15, A 8036 Graz, Austria
    Liver Int 25:367-79. 2005
    ..Furthermore, we investigated expression of the major bile salt uptake system Na(+)/taurocholate cotransporter NTCP (SLC10A1), since bile salt-coupled chemotherapeutics were proposed to increase therapeutic drug enrichment in HCC...
  41. ncbi request reprint Quantification of Staphylococcus aureus in unpasteurised bovine and caprine milk by real-time PCR
    Ingeborg Hein
    Institute for Milk Hygiene, Milk Technology, and Food Science, University for Veterinary Medicine, Veterinarplatz 1, 1210 Vienna, Austria
    Res Microbiol 156:554-63. 2005
    ..aureus cell, which is or has been present in the sample, this method offers the advantage of a retrospective analysis even of processed samples to aid food poisoning-related risk assessment...
  42. ncbi request reprint CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice
    Martin Wagner
    Laboratory of Experimental and Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Medicine, Medical University Graz, Auenbruggerplatz 15, A 8036 Graz, Austria
    Hepatology 42:420-30. 2005
    ....
  43. ncbi request reprint Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver
    Gernot Zollner
    Laboratory of Experimental and Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University Graz, Graz, Austria
    Am J Physiol Gastrointest Liver Physiol 289:G798-805. 2005
    ....
  44. ncbi request reprint Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans
    Hanns Ulrich Marschall
    Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Gastroenterology 129:476-85. 2005
    ..We aimed to study the molecular mechanisms of action of these drugs in humans...
  45. ncbi request reprint Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids
    Hanns Ulrich Marschall
    Karolinska Institutet, Department of Medicine at Karolinska University Hospital Huddinge, S 14186 Stockholm, Sweden
    J Lipid Res 47:582-92. 2006
    ..In conclusion, Fxr(-/-) mice detoxify accumulating bile acids in the liver by enhanced hydroxylation reactions probably catalyzed by Cyp3a11. The metabolites formed were excreted into urine, most likely with the participation of Mrp4...
  46. ncbi request reprint Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids
    Gernot Zollner
    Laboratory of Experimental and Molecular Hepatology, Div of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University Graz, Auenbruggerplatz 15, Graz A 8036, Austria
    Am J Physiol Gastrointest Liver Physiol 290:G923-32. 2006
    ..The induction of bile acid hydroxylation and Mrp4 was independent of FXR but could not counteract liver toxicity sufficiently. Limited effects of UDCA on Ost-alpha/Ost-beta may jeopardize its therapeutic efficacy...
  47. ncbi request reprint Standardization of diagnostic PCR for the detection of foodborne pathogens
    Burkhard Malorny
    Federal Institute for Health Protection of Consumers and Veterinary Medicine, Diedersdorfer Weg 1, 12277 Berlin, Germany
    Int J Food Microbiol 83:39-48. 2003
    ..The present review focuses on the harmonization procedure and standardization criteria for detection of foodborne pathogens by PCR. The progress of standardization so far and future perspectives of diagnostic PCR are discussed...
  48. ncbi request reprint Real-time PCR for the detection of Salmonella spp. in food: An alternative approach to a conventional PCR system suggested by the FOOD-PCR project
    Ingeborg Hein
    Institute of Milk Hygiene, Milk Technology, and Food Science, Department of Veterinary Public Health and Food Science, University of Veterinary Medicine, Veterinaerplatz 1, A 1210 Vienna, Austria
    J Microbiol Methods 66:538-47. 2006
    ..However, the productivity of UPB was sufficient, as all samples were positive with both real-time PCR methods, including those containing less than 300 CFU/ml enrichment broth (enrichment of 5 CFU/25 ml raw milk in UPB)...
  49. ncbi request reprint Smad-Sp1 complexes mediate TGFbeta-induced early transcription of oncogenic Smad7 in pancreatic cancer cells
    Kerstin Jungert
    Department of Gastroenterology, University of Ulm, 89081 Ulm, Germany
    Carcinogenesis 27:2392-401. 2006
    ..We thus conclude that Sp1 strongly contributes to the aberrant transcriptional response of transformed epithelial cells to TGFbeta stimulation...
  50. ncbi request reprint IGF-I and TGF-beta1 application by a poly-(D,L-lactide)-coated cage promotes intervertebral bone matrix formation in the sheep cervical spine
    Frank Kandziora
    Unfall und Wiederherstellungschirurgie, Universitätsklinikum Charité der Humboldt, Universität Berlin Campus Virchow, Klinikum, Berlin, Germany
    Spine (Phila Pa 1976) 27:1710-23. 2002
    ..A sheep cervical spine interbody fusion model was used to determine the effect of combined insulin-like growth factor-I (IGF-I) and transforming growth factor-beta-1 (TGF-beta1) applied by a poly-(D,L-lactide) (PDLLA)-coated cage...