Roland Veelken

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. pmc Effects of diabetes and hypertension on macrophage infiltration and matrix expansion in the rat kidney
    Andrea Hartner
    Children and Youth Hospital, University of Erlangen Nuremberg, Loschgestrasse 15, D 91054 Erlangen, Germany
    BMC Nephrol 6:6. 2005
  2. pmc Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID)
    Hans Peter Tony
    Medizinische Klinik und Poliklinik II, Universitatsklinikum Wurzburg, Klinikstr 6 8, 97070 Wurzburg, Germany
    Arthritis Res Ther 13:R75. 2011
  3. ncbi request reprint Effects of sympathetic nerves and angiotensin II on renal sodium and water handling in rats with common bile duct ligature
    Roland Veelken
    Dept of Medicine IV, Univ of Erlangen Nürnberg, Loschgestrasse 8, 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 288:F1267-75. 2005
  4. doi request reprint Sensory renal innervation: a kidney-specific firing activity due to a unique expression pattern of voltage-gated sodium channels?
    Wolfgang Freisinger
    Dept of Medicine 4, Univ of Erlangen Nürnberg, Loschgestraβe 8, 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 304:F491-7. 2013
  5. ncbi request reprint Strain differences in the development of hypertension and glomerular lesions induced by deoxycorticosterone acetate salt in mice
    Andrea Hartner
    Nephrology Research Laboratory, Loschgestrasse 8, D 91054 Erlangen, Germany
    Nephrol Dial Transplant 18:1999-2004. 2003
  6. ncbi request reprint Additional antiproteinuric effect of ultrahigh dose candesartan: a double-blind, randomized, prospective study
    Roland E Schmieder
    Universitatsklinikum Erlangen, Medizinische Klinik IV, Krankenhausstrasse 12, Erlangen 91054, Germany
    J Am Soc Nephrol 16:3038-45. 2005
  7. ncbi request reprint Extrarenal Na+ balance, volume, and blood pressure homeostasis in intact and ovariectomized deoxycorticosterone-acetate salt rats
    Jens Titze
    Department of Nephrology and Hypertension, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Hypertension 47:1101-7. 2006
  8. ncbi request reprint Angiotensin II formation in the kidney and nephrosclerosis in Ren-2 hypertensive rats
    Andrea Hartner
    University Hospital for Children and Adolescents, University of Erlangen Nuremberg, Erlangen, Germany
    Nephrol Dial Transplant 21:1778-85. 2006
  9. ncbi request reprint Serotonin 5-HT(3) receptors on mechanosensitive neurons with cardiac afferents
    Peter Linz
    Department of Internal Medicine, University of Erlangen Nurnberg, 91054 Erlangen, Germany
    Am J Physiol Heart Circ Physiol 282:H1828-35. 2002
  10. doi request reprint Tonic postganglionic sympathetic inhibition induced by afferent renal nerves?
    Tilmann Ditting
    Department of Internal Medicine 4, Nephrology and Hypertension, Friedrich Alexander University Erlangen, Ulmenweg 1, 91054 Erlangen, Germany
    Hypertension 59:467-76. 2012

Collaborators

Detail Information

Publications26

  1. pmc Effects of diabetes and hypertension on macrophage infiltration and matrix expansion in the rat kidney
    Andrea Hartner
    Children and Youth Hospital, University of Erlangen Nuremberg, Loschgestrasse 15, D 91054 Erlangen, Germany
    BMC Nephrol 6:6. 2005
    ..Inflammatory mechanisms contribute to renal damage in both diseases. We investigated whether hypertension and diabetes mellitus act synergistically to induce macrophage infiltration and matrix expansion in the kidney...
  2. pmc Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID)
    Hans Peter Tony
    Medizinische Klinik und Poliklinik II, Universitatsklinikum Wurzburg, Klinikstr 6 8, 97070 Wurzburg, Germany
    Arthritis Res Ther 13:R75. 2011
    ....
  3. ncbi request reprint Effects of sympathetic nerves and angiotensin II on renal sodium and water handling in rats with common bile duct ligature
    Roland Veelken
    Dept of Medicine IV, Univ of Erlangen Nürnberg, Loschgestrasse 8, 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 288:F1267-75. 2005
    ..We speculate that similar changes may contribute to long-term volume retention in liver cirrhosis...
  4. doi request reprint Sensory renal innervation: a kidney-specific firing activity due to a unique expression pattern of voltage-gated sodium channels?
    Wolfgang Freisinger
    Dept of Medicine 4, Univ of Erlangen Nürnberg, Loschgestraβe 8, 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 304:F491-7. 2013
    ..Our findings support that this is due to an increased expression and activation of TTX-resistant Navs...
  5. ncbi request reprint Strain differences in the development of hypertension and glomerular lesions induced by deoxycorticosterone acetate salt in mice
    Andrea Hartner
    Nephrology Research Laboratory, Loschgestrasse 8, D 91054 Erlangen, Germany
    Nephrol Dial Transplant 18:1999-2004. 2003
    ..We investigated its influence on the development of hypertension and renal injury following treatment with deoxycorticosterone acetate (DOCA) salt in several mouse strains...
  6. ncbi request reprint Additional antiproteinuric effect of ultrahigh dose candesartan: a double-blind, randomized, prospective study
    Roland E Schmieder
    Universitatsklinikum Erlangen, Medizinische Klinik IV, Krankenhausstrasse 12, Erlangen 91054, Germany
    J Am Soc Nephrol 16:3038-45. 2005
    ..57]; NS). No change in BP was noticed in response to the different doses of candesartan. These data indicate an additive antiproteinuric effect of ultrahigh dose of the angiotensin receptor blocker candesartan compared with standard dose...
  7. ncbi request reprint Extrarenal Na+ balance, volume, and blood pressure homeostasis in intact and ovariectomized deoxycorticosterone-acetate salt rats
    Jens Titze
    Department of Nephrology and Hypertension, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Hypertension 47:1101-7. 2006
    ..Extrarenal Na+ and volume balance seem to play an important role in long-term volume and MAP control...
  8. ncbi request reprint Angiotensin II formation in the kidney and nephrosclerosis in Ren-2 hypertensive rats
    Andrea Hartner
    University Hospital for Children and Adolescents, University of Erlangen Nuremberg, Erlangen, Germany
    Nephrol Dial Transplant 21:1778-85. 2006
    ..We tested the hypothesis that local angiotensin II formation occurs at sites of renal vascular and interstitial injury in this model...
  9. ncbi request reprint Serotonin 5-HT(3) receptors on mechanosensitive neurons with cardiac afferents
    Peter Linz
    Department of Internal Medicine, University of Erlangen Nurnberg, 91054 Erlangen, Germany
    Am J Physiol Heart Circ Physiol 282:H1828-35. 2002
    ..Angiotensin II had no influence. Hence, serotonin might decrease the mechanical sensitivity of afferent cardiac nerves controlling renal sympathetic nerve activity...
  10. doi request reprint Tonic postganglionic sympathetic inhibition induced by afferent renal nerves?
    Tilmann Ditting
    Department of Internal Medicine 4, Nephrology and Hypertension, Friedrich Alexander University Erlangen, Ulmenweg 1, 91054 Erlangen, Germany
    Hypertension 59:467-76. 2012
    ....
  11. ncbi request reprint Role of macula densa cyclooxygenase-2 in renovascular hypertension
    Andrea Hartner
    Department of Medicine IV, University of Erlangen Nurnberg, 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 284:F498-502. 2003
    ..Thus either COX-2 is not necessary for the macula densa mechanism or the macula densa is not important for maintaining high renin in renovascular hypertension...
  12. ncbi request reprint Renal denervation--implications for chronic kidney disease
    Roland Veelken
    Department of Nephrology and Hypertension, University Hospital, University Erlangen Nurnberg, Ulmenweg 18, 91054 Erlangen, Germany
    Nat Rev Nephrol 10:305-13. 2014
    ..Additional large randomized controlled trials of renal denervation in hypertensive and normotensive patients with CKD are required to precisely define the clinical value of the procedure in this population. ..
  13. ncbi request reprint Nonhypotensive dose of beta-adrenergic blocker ameliorates capillary deficits in the hearts of rats with moderate renal failure
    Kerstin Amann
    Department of Pathology, University of Erlangen Nurnberg, Krankenhausstr 8 10, 91054 Erlangen, Germany
    Virchows Arch 449:207-14. 2006
    ....
  14. ncbi request reprint Bimodality of cardiac vagal afferent C-fibres in the rat
    Roland Veelken
    Nephrologisches Labor, Department of Medicine IV, University of Erlangen Nurnberg, Loschgestrasse 8, 91054 Erlangen, Germany
    Pflugers Arch 446:516-22. 2003
    ..Our results emphasize the potential role of endogenous mediators in the afferent limb of cardiac reflexes...
  15. ncbi request reprint Renal sympathetic nerves modulate erythropoietin plasma levels after transient hemorrhage in rats
    Tilmann Ditting
    Department of Nephrology, Friedrich Alexander Univ Erlangen Nürnberg, Erlangen, Germany
    Am J Physiol Renal Physiol 293:F1099-106. 2007
    ..Renal sympathoinhibition during hypotensive hemorrhage might help to preserve sufficient oxygenation of renal tissue by modulation of hemodynamic mechanisms that act to adapt renal oxygen availability to demand...
  16. ncbi request reprint Effect of the angiotensinogen genotype on experimental hypertension in mice
    Claudia Handtrack
    Department of Nephrology and Hypertension, University of Erlangen Nuremberg, Erlangen, Germany
    J Mol Med (Berl) 85:343-50. 2007
    ..We conclude that the Agt genotype exerts a marked effect on blood pressure in a low-renin form of hypertension but no effect in the face of stimulated renin, at least in mice...
  17. ncbi request reprint Transient receptor potential vanilloid type 1 receptors in hypertensive renal damage: a promising therapeutic target?
    Tilmann Ditting
    Hypertension 52:213-4. 2008
  18. ncbi request reprint Renal injury in streptozotocin-diabetic Ren2-transgenic rats is mainly dependent on hypertension, not on diabetes
    Andrea Hartner
    Children and Youth Hospital, University of Erlangen Nuremberg, Erlangen, Germany
    Am J Physiol Renal Physiol 292:F820-7. 2007
    ..However, the long-term course of this animal model resembles severe hypertensive nephrosclerosis, rather than progressive diabetic nephropathy...
  19. ncbi request reprint Sensory neurons with afferents from hind limbs: enhanced sensitivity in secondary hypertension
    Peter Linz
    Department of Internal Medicine 4 Nephrology and Hypertension, University of Erlangen Nurnberg, Erlangen, Germany
    Hypertension 47:527-31. 2006
    ..We speculate that this observation may indicate an increased activity of these neurons, their axons, and neurotransmitters in the control of resistance vessels in hypertension...
  20. ncbi request reprint Mechanosensitive cardiac C-fiber response to changes in left ventricular filling, coronary perfusion pressure, hemorrhage, and volume expansion in rats
    Tilmann Ditting
    Department of Nephrology, Johann Wolfgang University, Frankfurt, Germany
    Am J Physiol Heart Circ Physiol 288:H541-52. 2005
    ..Thus neither LVEDP nor CPP fully accounts directly for afferent C-fiber and reflex sympathetic responses. The intrinsic afferent stimuli and receptive fields accounting for reflex sympathoinhibition still remain cryptic...
  21. ncbi request reprint Putative role of epithelial sodium channels (ENaC) in the afferent limb of cardio renal reflexes in rats
    Tilmann Ditting
    Department of Nephrology, J W Goethe University, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
    Basic Res Cardiol 98:388-400. 2003
    ..Other ion channels might be involved. Furthermore the observed findings in vivo could also be due to unspecific disturbance of afferent signal conduction...
  22. ncbi request reprint Type 2 diabetic nephropathy: never too early to treat?
    Karl F Hilgers
    J Am Soc Nephrol 16:574-5. 2005
  23. pmc Autonomic renal denervation ameliorates experimental glomerulonephritis
    Roland Veelken
    Department of Nephrology and Hypertension, University of Erlangen Nuremberg, Erlangen, Germany
    J Am Soc Nephrol 19:1371-8. 2008
    ....
  24. ncbi request reprint How does minor renal dysfunction influence cardiovascular risk and the management of cardiovascular disease?
    Tobias Pinkau
    Department of Cardiology, German Heart Center, Munich, Germany
    J Am Soc Nephrol 15:517-23. 2004
    ..Further investigations should focus on the causes of and possible preventive interventions for the staggering cardiovascular risk in the ever-increasing number of people with minor renal dysfunction...
  25. ncbi request reprint Dynamic expression patterns of transforming growth factor-beta(2) and transforming growth factor-beta receptors in experimental glomerulonephritis
    Andrea Hartner
    Medizinische Klinik IV, Universität Erlangen Nuremberg, Erlangen, Germany
    J Mol Med (Berl) 81:32-42. 2003
    ..1 nephritis. These results are in keeping with the notion that TGF-beta(2) and its receptors participate in the pathogenesis and/or resolution of this transient form of glomerulonephritis...
  26. ncbi request reprint Neutral endopeptidase inhibition: the potential of a new therapeutic approach in cardiovascular disease evolves
    Roland Veelken
    J Hypertens 20:599-603. 2002