Andrea Steinborn

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. doi request reprint Distinct subsets of regulatory T cells during pregnancy: is the imbalance of these subsets involved in the pathogenesis of preeclampsia?
    Andrea Steinborn
    Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany
    Clin Immunol 129:401-12. 2008
  2. pmc Pregnancy-associated diseases are characterized by the composition of the systemic regulatory T cell (Treg) pool with distinct subsets of Tregs
    A Steinborn
    Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany
    Clin Exp Immunol 167:84-98. 2012
  3. doi request reprint Small for gestational age (SGA) neonates show reduced suppressive activity of their regulatory T cells
    Andrea Steinborn
    Department of Obstetrics and Gynecology, University of Heidelberg, Voss Strasse 9, 69115 Heidelberg, Germany
    Clin Immunol 134:188-97. 2010
  4. ncbi request reprint Early detection of decreased soluble HLA-G levels in the maternal circulation predicts the occurrence of preeclampsia and intrauterine growth retardation during further course of pregnancy
    Andrea Steinborn
    Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany
    Am J Reprod Immunol 57:277-86. 2007
  5. ncbi request reprint Prolonged preterm rupture of fetal membranes, a consequence of an increased maternal anti-fetal T cell responsiveness
    Andrea Steinborn
    Department of Obstetrics and Gynecology, University of Frankfurt, Germany
    Pediatr Res 58:648-53. 2005
  6. doi request reprint The extent of HLA-DR expression on HLA-DR(+) Tregs allows the identification of patients with clinically relevant borderline rejection
    Matthias Schaier
    Department of Nephrology, University of Heidelberg, D 69120 Heidelberg, Germany
    Transpl Int 26:290-9. 2013
  7. doi request reprint Methylprednisolone treatment increases the proportion of the highly suppressive HLA-DR(+)-Treg-cells in transplanted patients
    Nicole Seissler
    Department of Nephrology, University of Heidelberg, Germany
    Transpl Immunol 27:157-61. 2012
  8. pmc DR(high+)CD45RA(-)-Tregs potentially affect the suppressive activity of the total Treg pool in renal transplant patients
    Matthias Schaier
    Department of Nephrology, University of Heidelberg, Heidelberg, Germany
    PLoS ONE 7:e34208. 2012
  9. doi request reprint Aberrant ICOS+ -T cell differentiation in women with spontaneous preterm labor
    Florian Kälble
    Department of Medicine I Nephrology, University of Heidelberg, Heidelberg, Germany
    Am J Reprod Immunol 76:415-425. 2016
  10. doi request reprint Term and preterm labor: decreased suppressive activity and changes in composition of the regulatory T-cell pool
    Linda Schober
    Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany
    Immunol Cell Biol 90:935-44. 2012

Collaborators

Detail Information

Publications17

  1. doi request reprint Distinct subsets of regulatory T cells during pregnancy: is the imbalance of these subsets involved in the pathogenesis of preeclampsia?
    Andrea Steinborn
    Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany
    Clin Immunol 129:401-12. 2008
    ....
  2. pmc Pregnancy-associated diseases are characterized by the composition of the systemic regulatory T cell (Treg) pool with distinct subsets of Tregs
    A Steinborn
    Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany
    Clin Exp Immunol 167:84-98. 2012
    ....
  3. doi request reprint Small for gestational age (SGA) neonates show reduced suppressive activity of their regulatory T cells
    Andrea Steinborn
    Department of Obstetrics and Gynecology, University of Heidelberg, Voss Strasse 9, 69115 Heidelberg, Germany
    Clin Immunol 134:188-97. 2010
    ..We propose that the level of FoxP3 expression in the fetal Tregs may be a potential regulator of their suppressive activity...
  4. ncbi request reprint Early detection of decreased soluble HLA-G levels in the maternal circulation predicts the occurrence of preeclampsia and intrauterine growth retardation during further course of pregnancy
    Andrea Steinborn
    Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany
    Am J Reprod Immunol 57:277-86. 2007
    ....
  5. ncbi request reprint Prolonged preterm rupture of fetal membranes, a consequence of an increased maternal anti-fetal T cell responsiveness
    Andrea Steinborn
    Department of Obstetrics and Gynecology, University of Frankfurt, Germany
    Pediatr Res 58:648-53. 2005
    ..By contrast, data from women with PPROM suggest an increased maternal T cell response specifically toward the fetal HLA antigens...
  6. doi request reprint The extent of HLA-DR expression on HLA-DR(+) Tregs allows the identification of patients with clinically relevant borderline rejection
    Matthias Schaier
    Department of Nephrology, University of Heidelberg, D 69120 Heidelberg, Germany
    Transpl Int 26:290-9. 2013
    ....
  7. doi request reprint Methylprednisolone treatment increases the proportion of the highly suppressive HLA-DR(+)-Treg-cells in transplanted patients
    Nicole Seissler
    Department of Nephrology, University of Heidelberg, Germany
    Transpl Immunol 27:157-61. 2012
    ....
  8. pmc DR(high+)CD45RA(-)-Tregs potentially affect the suppressive activity of the total Treg pool in renal transplant patients
    Matthias Schaier
    Department of Nephrology, University of Heidelberg, Heidelberg, Germany
    PLoS ONE 7:e34208. 2012
    ..Therefore, both the monitoring of its percentage within the total Treg pool and the monitoring of the HLA-DR MFI of the DR(+)CD45RA(-)-Treg subset may be useful tools for the prediction of graft rejection...
  9. doi request reprint Aberrant ICOS+ -T cell differentiation in women with spontaneous preterm labor
    Florian Kälble
    Department of Medicine I Nephrology, University of Heidelberg, Heidelberg, Germany
    Am J Reprod Immunol 76:415-425. 2016
    ..Recent studies revealed appropriate differentiation of recent thymic emigrant (RTE)-regulatory T cells (Tregs) to be crucial for maintaining healthy pregnancy. Currently, the role of responder T cells (Tresps) is not known...
  10. doi request reprint Term and preterm labor: decreased suppressive activity and changes in composition of the regulatory T-cell pool
    Linda Schober
    Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany
    Immunol Cell Biol 90:935-44. 2012
    ..Therefore, it becomes apparent that the mechanisms inducing term or preterm labor may be completely different...
  11. ncbi request reprint Soluble HLA-DR levels in the maternal circulation of normal and pathologic pregnancy
    Andrea Steinborn
    Department of Obstetrics and Gynecology, University of Frankfurt Main, Germany
    Am J Obstet Gynecol 188:473-9. 2003
    ..The purpose of this study was to determine that circulating HLA-DR molecules are important candidates for the monitoring of maternal immunostimulation and immunosuppression...
  12. doi request reprint The role of recent thymic emigrant-regulatory T-cell (RTE-Treg) differentiation during pregnancy
    Miriam I Wagner
    Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany
    Immunol Cell Biol 93:858-67. 2015
    ..Presumably, this differentiation of RTE-Tregs, which was impaired in preeclampsia patients, ensures the improved suppressive activity of the CD45RA(+)-naive Treg pool and thus retains the maintenance of pregnancy. ..
  13. ncbi request reprint The presence of gestational diabetes is associated with increased detection of anti-HLA-class II antibodies in the maternal circulation
    Andrea Steinborn
    Department of Obstetrics and Gynecology, University of Heidelberg, Germany
    Am J Reprod Immunol 56:124-34. 2006
    ..The aim of this study was to assess anti-HLA-class I and -II antibodies as markers for an aberrant immunostimulation in women with GD...
  14. doi request reprint A distinct subset of HLA-DR+-regulatory T cells is involved in the induction of preterm labor during pregnancy and in the induction of organ rejection after transplantation
    Anna Kisielewicz
    Department of Obstetrics and Gynecology, University of Heidelberg, Voss Strasse 9, 69115 Heidelberg, Germany
    Clin Immunol 137:209-20. 2010
    ....
  15. ncbi request reprint Breast cancer cell-derived cytokines, macrophages and cell adhesion: implications for metastasis
    Christine Eichbaum
    Department of Gynecology and Obstetrics, University of Heidelberg Medical School, Voss Strasse 9, D 69115 Heidelberg, Germany
    Anticancer Res 31:3219-27. 2011
    ..The aim of this study was to characterize the interrelations between breast cancer cell-secreted cytokines, macrophages and E-selectin-mediated cancer cell adhesion and their role in metastasis of breast cancer...
  16. ncbi request reprint The significance of intracardiac Doppler sonography in terms of fetal growth retardation
    Ismini Staboulidou
    Department of Obstetrics and Gynecology, University Medical School of Hanover, Carl Neuberg Str 1, 30625 Hannover, Germany
    Arch Gynecol Obstet 276:35-42. 2007
    ..This study aimed at evaluating the clinical value of the intracardiac Doppler sonography (IDS) and at scrutinizing its usefulness during the supervision of the pregnancy of intrauterine growth restricted (IUGR) fetuses...
  17. ncbi request reprint High levels of circulatory erythroblasts and cell-free DNA prior to intrauterine fetal death
    Xiao Yan Zhong
    Prenat Diagn 26:1272-3. 2006