Hans Georg Simank

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi request reprint Comparison of results of core decompression and intertrochanteric osteotomy for nontraumatic osteonecrosis of the femoral head using Cox regression and survivorship analysis
    H G Simank
    Department of Orthopaedics I, University of Heidelberg, Heidelberg, Germany
    J Arthroplasty 16:790-4. 2001
  2. ncbi request reprint Bone morphogenetic protein-2 and growth and differentiation factor-5 enhance the healing of necrotic bone in a sheep model
    H G Simank
    Department of Orthopaedics, University of Heidelberg, Germany
    Growth Factors 19:247-57. 2001
  3. ncbi request reprint [Growth and differentiation factor 5 (GDF-5) composite improves the healing of necrosis of the femoral head in a sheep model. Analysis of an animal model]
    H G Simank
    Orthopädische Universitätsklinik Heidelberg
    Orthopade 33:68-75. 2004
  4. ncbi request reprint [Joint empyema]
    H G Simank
    Orthopädische Klinik der Universität Heidelberg
    Orthopade 33:327-31. 2004
  5. ncbi request reprint Effects of local application of growth and differentiation factor-5 (GDF-5) in a full-thickness cartilage defect model
    Hans Georg Simank
    Orthopädische Universitätsklinik Heidelberg, Heidelberg, Germany
    Growth Factors 22:35-43. 2004
  6. ncbi request reprint Evaluation of mineralized collagen and alpha-tricalcium phosphate as scaffolds for tissue engineering of bone using human mesenchymal stem cells
    Philipp Niemeyer
    Department of Orthopedic Surgery, University of Heidelberg, Heidelberg, Germany
    Cells Tissues Organs 177:68-78. 2004
  7. ncbi request reprint Local application of a collagen type I/hyaluronate matrix and growth and differentiation factor 5 influences the closure of osteochondral defects in a minipig model by enchondral ossification
    Martin Jung
    Department of Orthopaedic Surgery, University of Heidelberg, Heidelberg, Germany
    Growth Factors 24:225-32. 2006
  8. ncbi request reprint Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects
    Florian Geiger
    Department of Orthopaedic Surgery, University of Heidelberg, Heidelberg, Germany
    J Bone Miner Res 20:2028-35. 2005
  9. doi request reprint Implant stability in the treatment of MRSA bone implant infections with linezolid versus vancomycin in a rabbit model
    Kerstin Schroeder
    Department of Orthopedic Surgery, University of Heidelberg, Schlierbacher Landstrasse 200a, D 69118 Heidelberg, Germany
    J Orthop Res 30:190-5. 2012
  10. ncbi request reprint Ectopic bone formation associated with mesenchymal stem cells in a resorbable calcium deficient hydroxyapatite carrier
    Philip Kasten
    Department of Orthopaedic Surgery, University of Heidelberg, Schlierbacher Landstr 200A, 69118 Heidelberg, Germany
    Biomaterials 26:5879-89. 2005

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Comparison of results of core decompression and intertrochanteric osteotomy for nontraumatic osteonecrosis of the femoral head using Cox regression and survivorship analysis
    H G Simank
    Department of Orthopaedics I, University of Heidelberg, Heidelberg, Germany
    J Arthroplasty 16:790-4. 2001
    ..For postcollapse hips, intertrochanteric osteotomy should be considered...
  2. ncbi request reprint Bone morphogenetic protein-2 and growth and differentiation factor-5 enhance the healing of necrotic bone in a sheep model
    H G Simank
    Department of Orthopaedics, University of Heidelberg, Germany
    Growth Factors 19:247-57. 2001
    ....
  3. ncbi request reprint [Growth and differentiation factor 5 (GDF-5) composite improves the healing of necrosis of the femoral head in a sheep model. Analysis of an animal model]
    H G Simank
    Orthopädische Universitätsklinik Heidelberg
    Orthopade 33:68-75. 2004
    ..The animals were sacrificed 6 and 12 weeks after implantation and the femora were harvested. The specimens were investigated by microradiography, computed tomography, and histologically...
  4. ncbi request reprint [Joint empyema]
    H G Simank
    Orthopädische Klinik der Universität Heidelberg
    Orthopade 33:327-31. 2004
    ..Early surgical revision is recommended in cases of insufficient recovery...
  5. ncbi request reprint Effects of local application of growth and differentiation factor-5 (GDF-5) in a full-thickness cartilage defect model
    Hans Georg Simank
    Orthopädische Universitätsklinik Heidelberg, Heidelberg, Germany
    Growth Factors 22:35-43. 2004
    ..We assume that recombinant GDF-5 contained on the carrier is probably able to accelerate the regeneration of the osteochondral defect owing to its availability. However, control of the protein delivery may require further investigation...
  6. ncbi request reprint Evaluation of mineralized collagen and alpha-tricalcium phosphate as scaffolds for tissue engineering of bone using human mesenchymal stem cells
    Philipp Niemeyer
    Department of Orthopedic Surgery, University of Heidelberg, Heidelberg, Germany
    Cells Tissues Organs 177:68-78. 2004
    ..TCP = 0.046) and 3D cell alignment (cell infiltration up to 500 vs. 200 microm). In conclusion, our data suggest that mineralized collagen is a promising candidate for use as a scaffold in tissue engineering of bone...
  7. ncbi request reprint Local application of a collagen type I/hyaluronate matrix and growth and differentiation factor 5 influences the closure of osteochondral defects in a minipig model by enchondral ossification
    Martin Jung
    Department of Orthopaedic Surgery, University of Heidelberg, Heidelberg, Germany
    Growth Factors 24:225-32. 2006
    ....
  8. ncbi request reprint Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects
    Florian Geiger
    Department of Orthopaedic Surgery, University of Heidelberg, Heidelberg, Germany
    J Bone Miner Res 20:2028-35. 2005
    ..It was shown that 0.1 and 1 mg of pVEGF165-GAM led to a significant increase in vascularization and bone regeneration in defects that would otherwise have led to atrophic nonunions...
  9. doi request reprint Implant stability in the treatment of MRSA bone implant infections with linezolid versus vancomycin in a rabbit model
    Kerstin Schroeder
    Department of Orthopedic Surgery, University of Heidelberg, Schlierbacher Landstrasse 200a, D 69118 Heidelberg, Germany
    J Orthop Res 30:190-5. 2012
    ..Our data indicate that both treatment regimens improved implant stability...
  10. ncbi request reprint Ectopic bone formation associated with mesenchymal stem cells in a resorbable calcium deficient hydroxyapatite carrier
    Philip Kasten
    Department of Orthopaedic Surgery, University of Heidelberg, Schlierbacher Landstr 200A, 69118 Heidelberg, Germany
    Biomaterials 26:5879-89. 2005
    ..Ectopic bone formation in the novel biomaterial CDHA varied considerably with the cell pool and was at least equal to beta-TCP blocks...
  11. pmc Establishment of a new methicillin resistant Staphylococcus aureus animal model of osteomyelitis
    Lars Helbig
    Department of Orthopedics, Trauma Surgery and Paraplegiology, Heidelberg University Hospital, Heidelberg, Germany
    Int Orthop 38:891-7. 2014
    ..The aim of this study was to establish a MRSA peri-implant osteomyelitis animal model for future testing of new anti-microbiological agents under typical MRSA infection conditions...
  12. ncbi request reprint Improved osseointegration of PTFEP-coated titanium implants
    Felix Zeifang
    Department of Orthopedic Surgery, University of Heidelberg, Germany
    Med Sci Monit 14:BR35-40. 2008
    ..However, there is limited clinical experience of PTFEP as a coating for bone implants. Therefore PTFEP-coated titanium implants in an animal model were examined...
  13. ncbi request reprint The influence of surface coatings of dicalcium phosphate (DCPD) and growth and differentiation factor-5 (GDF-5) on the stability of titanium implants in vivo
    Hans Georg Simank
    Orthopaedisches Centrum Hochfranken OCH, Orthopaedische Gemeinschafspraxis, Eppenreuther Strasse 28, 95032 Hof, Germany
    Biomaterials 27:3988-94. 2006
    ..01). Our findings indicate the positive effect of DCPD and GDF-5 coatings on stability of titanium implants. Results demonstrate the non-destructive testing to be an effective method to evaluate mechanical stability of implants...
  14. ncbi request reprint [Method of non-destructive mechanical testing of new surface coatings for prostheses]
    Felix Zeifang
    Orthopädische Universitätsklinik Heidelberg, Deutschland
    Biomed Tech (Berl) 51:3-7. 2006
    ..In summary, the method of non-destructive mechanical testing represents an ideal tool to study new surface coatings and surface processing methods for prostheses...
  15. ncbi request reprint Immunohistochemical demonstration of -(carboxymethyl)lysine protein adducts in normal and osteoarthritic cartilage
    Wolfgang Schwab
    Institute of Anatomy, Technical University Dresden, Medical Faculty Carl Gustav Carus, Fiedlerstrasse 42, Germany
    Histochem Cell Biol 117:541-6. 2002
    ..Therefore, the inhibition of CML accumulation may represent an effective therapeutic strategy to prevent severe OA cartilage injury...