Hinrich Schulenburg

Summary

Affiliation: University of Kiel
Country: Germany

Publications

  1. pmc Infection routes matter in population-specific responses of the red flour beetle to the entomopathogen Bacillus thuringiensis
    Sarah Behrens
    Institute for Evolution and Biodiversity, University of Munster, Hüfferstr, 1, 48149 Munster, Germany
    BMC Genomics 15:445. 2014
  2. pmc Lotka-Volterra dynamics kills the Red Queen: population size fluctuations and associated stochasticity dramatically change host-parasite coevolution
    Chaitanya S Gokhale
    Evolutionary Theory Group, Max Planck Institute for Evolutionary Biology, August Thienemann Str 2, 24306, Plon, Germany
    BMC Evol Biol 13:254. 2013
  3. pmc Gene-environment and protein-degradation signatures characterize genomic and phenotypic diversity in wild Caenorhabditis elegans populations
    Rita J M Volkers
    Laboratory of Nematology, Wageningen University, Droevendaalsesteeg 1, Wageningen 6708PB, The Netherlands
    BMC Biol 11:93. 2013
  4. pmc The prevalence of Caenorhabditis elegans across 1.5 years in selected North German locations: the importance of substrate type, abiotic parameters, and Caenorhabditis competitors
    Carola Petersen
    Department of Evolutionary Ecology and Genetics, Zoological Institute, Christian Albrechts University, Am Botanischen Garten 1 9, 24118 Kiel, Germany
    BMC Ecol 14:4. 2014
  5. pmc Introduction. Ecological immunology
    Hinrich Schulenburg
    Zoological Institute, University of Kiel, Am Botanischen Garten, 24098 Kiel, Germany
    Philos Trans R Soc Lond B Biol Sci 364:3-14. 2009
  6. pmc Sex differences in host defence interfere with parasite-mediated selection for outcrossing during host-parasite coevolution
    Leila Masri
    Department of Evolutionary Ecology and Genetics, Zoological Institute, Christian Albrechts University of Kiel, Kiel, Germany
    Ecol Lett 16:461-8. 2013
  7. pmc Association between clinical antibiotic resistance and susceptibility of Pseudomonas in the cystic fibrosis lung
    Gunther Jansen
    Evolutionary Ecology and Genetics, Zoological Institute, University of Kiel, Am Botanischen Garten 1 9, 24118 Kiel, Germany
    Evol Med Public Health 2016:182-94. 2016
  8. pmc The native microbiome of the nematode Caenorhabditis elegans: gateway to a new host-microbiome model
    Philipp Dirksen
    Department of Evolutionary Ecology and Genetics, Zoological Institute, Christian Albrechts University, Am Botanischen Garten 3 9, 24118, Kiel, Germany
    BMC Biol 14:38. 2016
  9. doi request reprint GATA transcription factor as a likely key regulator of the Caenorhabditis elegans innate immune response against gut pathogens
    Wentao Yang
    Department of Evolutionary Ecology and Genetics, Zoological Institute, University of Kiel, D 24098 Kiel, Germany
    Zoology (Jena) 119:244-53. 2016
  10. pmc Travelling at a slug's pace: possible invertebrate vectors of Caenorhabditis nematodes
    Carola Petersen
    Department of Evolutionary Ecology and Genetics, Zoological Institute Christian Albrechts University, Am Botanischen Garten 1 9, 24118, Kiel, Germany
    BMC Ecol 15:19. 2015

Collaborators

Detail Information

Publications26

  1. pmc Infection routes matter in population-specific responses of the red flour beetle to the entomopathogen Bacillus thuringiensis
    Sarah Behrens
    Institute for Evolution and Biodiversity, University of Munster, Hüfferstr, 1, 48149 Munster, Germany
    BMC Genomics 15:445. 2014
    ..castaneum populations--one recently collected population (Cro1) and a commonly used laboratory strain (SB)--were analyzed using a next generation RNA sequencing approach...
  2. pmc Lotka-Volterra dynamics kills the Red Queen: population size fluctuations and associated stochasticity dramatically change host-parasite coevolution
    Chaitanya S Gokhale
    Evolutionary Theory Group, Max Planck Institute for Evolutionary Biology, August Thienemann Str 2, 24306, Plon, Germany
    BMC Evol Biol 13:254. 2013
    ..This belief is founded on previous theoretical work, which assumes infinite or constant population size. To what extent are such sustained oscillations realistic?..
  3. pmc Gene-environment and protein-degradation signatures characterize genomic and phenotypic diversity in wild Caenorhabditis elegans populations
    Rita J M Volkers
    Laboratory of Nematology, Wageningen University, Droevendaalsesteeg 1, Wageningen 6708PB, The Netherlands
    BMC Biol 11:93. 2013
    ..It is therefore essential to explore the full potential of the natural genetic variation and evolutionary context of the genotype-phenotype map in wild C. elegans populations...
  4. pmc The prevalence of Caenorhabditis elegans across 1.5 years in selected North German locations: the importance of substrate type, abiotic parameters, and Caenorhabditis competitors
    Carola Petersen
    Department of Evolutionary Ecology and Genetics, Zoological Institute, Christian Albrechts University, Am Botanischen Garten 1 9, 24118 Kiel, Germany
    BMC Ecol 14:4. 2014
    ..In order to extend these findings, we sampled C. elegans continuously across 1.5 years from rotting apples and compost heaps in three North German locations...
  5. pmc Introduction. Ecological immunology
    Hinrich Schulenburg
    Zoological Institute, University of Kiel, Am Botanischen Garten, 24098 Kiel, Germany
    Philos Trans R Soc Lond B Biol Sci 364:3-14. 2009
    ..Our review summarizes the concepts of current importance and directs the reader to promising future research avenues that will deepen our understanding of the defence against parasites and pathogens...
  6. pmc Sex differences in host defence interfere with parasite-mediated selection for outcrossing during host-parasite coevolution
    Leila Masri
    Department of Evolutionary Ecology and Genetics, Zoological Institute, Christian Albrechts University of Kiel, Kiel, Germany
    Ecol Lett 16:461-8. 2013
    ..As sex differences in immunity are widespread, such interference of opposing selective constraints is likely of central importance during host adaptation to a coevolving parasite...
  7. pmc Association between clinical antibiotic resistance and susceptibility of Pseudomonas in the cystic fibrosis lung
    Gunther Jansen
    Evolutionary Ecology and Genetics, Zoological Institute, University of Kiel, Am Botanischen Garten 1 9, 24118 Kiel, Germany
    Evol Med Public Health 2016:182-94. 2016
    ..Here, we investigate correlations of sensitivity and resistance profiles of Pseudomonas aeruginosa that naturally adapted to antibiotics in the cystic fibrosis lung...
  8. pmc The native microbiome of the nematode Caenorhabditis elegans: gateway to a new host-microbiome model
    Philipp Dirksen
    Department of Evolutionary Ecology and Genetics, Zoological Institute, Christian Albrechts University, Am Botanischen Garten 3 9, 24118, Kiel, Germany
    BMC Biol 14:38. 2016
    ..coli strain as food. Here, we characterize for the first time the native microbiome of C. elegans and assess its influence on nematode life history characteristics...
  9. doi request reprint GATA transcription factor as a likely key regulator of the Caenorhabditis elegans innate immune response against gut pathogens
    Wentao Yang
    Department of Evolutionary Ecology and Genetics, Zoological Institute, University of Kiel, D 24098 Kiel, Germany
    Zoology (Jena) 119:244-53. 2016
    ..Taken together, our analysis of the worm's transcriptional response to microbes provides a new perspective on the C. elegans immune system, which we propose to be coordinated by GATA transcription factor ELT-2 in the gut. ..
  10. pmc Travelling at a slug's pace: possible invertebrate vectors of Caenorhabditis nematodes
    Carola Petersen
    Department of Evolutionary Ecology and Genetics, Zoological Institute Christian Albrechts University, Am Botanischen Garten 1 9, 24118, Kiel, Germany
    BMC Ecol 15:19. 2015
    ..elegans and two related species, especially C. remanei, and combined these screens with an experimental analysis of persistence in one of the vector taxa...
  11. pmc Diversification and adaptive sequence evolution of Caenorhabditis lysozymes (Nematoda: Rhabditidae)
    Hinrich Schulenburg
    Department of Animal Evolutionary Ecology, Zoological Institute, University of Tuebingen, Auf der Morgenstelle 28, 72076 Tuebingen, Germany
    BMC Evol Biol 8:114. 2008
    ..Whereas most organisms have only few lysozyme genes, nematodes of the genus Caenorhabditis possess a surprisingly large repertoire of up to 15 genes...
  12. pmc Contrasting invertebrate immune defense behaviors caused by a single gene, the Caenorhabditis elegans neuropeptide receptor gene npr-1
    Rania Nakad
    Department of Evolutionary Ecology and Genetics, Zoological Institute, University of Kiel, 24098, Kiel, Germany
    BMC Genomics 17:280. 2016
    ..Recent work suggests that invertebrate immune defense can be more specific at least at the phenotypic level. The underlying genetic mechanisms are as yet poorly understood...
  13. doi request reprint WormExp: a web-based application for a Caenorhabditis elegans-specific gene expression enrichment analysis
    Wentao Yang
    Evolutionary Ecology and Genetics, Zoological Institute, CAU Kiel, 24118 Kiel, Germany
    Bioinformatics 32:943-5. 2016
    ....
  14. pmc Antimicrobial effectors in the nematode Caenorhabditis elegans: an outgroup to the Arthropoda
    Katja Dierking
    Department of Evolutionary Ecology and Genetics, University of Kiel, Kiel 24098, Germany
    Philos Trans R Soc Lond B Biol Sci 371:. 2016
    ....
  15. pmc ABSSeq: a new RNA-Seq analysis method based on modelling absolute expression differences
    Wentao Yang
    Evolutionary Ecology and Genetics, Zoological Institute, CAU Kiel, Am Botanischen Garten 9, 24118, Kiel, Germany
    BMC Genomics 17:541. 2016
    ..Yet, for identification of these subsequently analysed genes, most studies use an additional minimal threshold of differential expression that is not captured by the applied statistical procedures...
  16. doi request reprint High Innate Immune Specificity through Diversified C-Type Lectin-Like Domain Proteins in Invertebrates
    Barbara Pees
    Department of Evolutionary Ecology and Genetics, Zoological Institute, Christian Albrechts University of Kiel, Kiel, Germany
    J Innate Immun 8:129-42. 2016
    ..In spite of recent achievements, the exact functions of the diversified invertebrate CTLD genes are still largely unknown. Our review therefore specifically discusses promising research approaches to rectify this knowledge gap. ..
  17. pmc Host-Pathogen Coevolution: The Selective Advantage of Bacillus thuringiensis Virulence and Its Cry Toxin Genes
    Leila Masri
    Department of Evolutionary Ecology and Genetics, Zoological Institute, Christian Albrechts University of Kiel, Kiel, Germany Department of Animal Evolutionary Ecology, Institute of Evolution and Ecology, University of Tuebingen, Tuebingen, Germany
    PLoS Biol 13:e1002169. 2015
    ..To our knowledge, this study is the first to characterize the pathogen genes involved in coevolutionary adaptation in an animal host-pathogen interaction system. ..
  18. pmc Evolutionary Transition from Pathogenicity to Commensalism: Global Regulator Mutations Mediate Fitness Gains through Virulence Attenuation
    Gunther Jansen
    Evolutionary Ecology and Genetics, Zoological Institute, University of Kiel, Kiel, Germany
    Mol Biol Evol 32:2883-96. 2015
    ..Nevertheless, the outcome of evolution was comparable across host types. Commensalism can thus evolve independently of host immune state solely as a side-effect of bacterial adaptation to novel hosts. ..
  19. doi request reprint Why we need more ecology for genetic models such as C. elegans
    Carola Petersen
    Evolutionary Ecology and Genetics, University of Kiel, 24098 Kiel, Germany
    Trends Genet 31:120-7. 2015
    ....
  20. doi request reprint Activation of the Caenorhabditis elegans FOXO family transcription factor DAF-16 by pathogenic Bacillus thuringiensis
    Jun Wang
    Department of Animal Evolutionary Ecology, Zoological Institute, University of Tuebingen, Auf der Morgenstelle 28, 72076 Tuebingen, Germany
    Dev Comp Immunol 37:193-201. 2012
    ..Taken together, our data highlight that a FOXO transcription factor directly responds to pathogens and thus contributes to immune defence...
  21. doi request reprint Host-parasite coevolution: why changing population size matters
    Andrei Papkou
    Department of Evolutionary Ecology and Genetics, Christian Albrechts University of Kiel, 24098, Kiel, Germany
    Zoology (Jena) 119:330-8. 2016
    ....
  22. doi request reprint Overlapping and unique signatures in the proteomic and transcriptomic responses of the nematode Caenorhabditis elegans toward pathogenic Bacillus thuringiensis
    Wentao Yang
    Evolutionary Ecology and Genetics, Zoological Institute, Christian Albrechts University of Kiel, Germany
    Dev Comp Immunol 51:1-9. 2015
    ..elegans response to infection is shaped by changes beyond transcription. Such effects appear to be influenced by AMP-activated protein kinases (AMPKs), which may thus represent previously unknown regulators of C. elegans immune defense. ..
  23. doi request reprint Evolutionary links between reproductive morphology, ecology and mating behavior in opisthobranch gastropods
    Nils Anthes
    Animal Evolutionary Ecology, Zoological Institute, Eberhard Karls Universitat Tubingen, Auf der Morgenstelle 28, 72076 Tubingen, Germany
    Evolution 62:900-16. 2008
    ..We finally outline approaches for experimentally assessing the proposed functional links that underlie the evolutionary correlations revealed by our study...
  24. pmc Genomics of rapid adaptation to antibiotics: convergent evolution and scalable sequence amplification
    David Laehnemann
    Department of Evolutionary Ecology and Genetics, University of Kiel, Germany
    Genome Biol Evol 6:1287-301. 2014
    ..Of the identified genomic changes, sequence amplification seems to represent the most potent, albeit costly genomic response mechanism to high antibiotic stress. ..
  25. doi request reprint Experimental evolution as an efficient tool to dissect adaptive paths to antibiotic resistance
    Gunther Jansen
    Department of Evolutionary Ecology and Genetics, Zoological Institute, Christian Albrechts University of Kiel, Germany Electronic address
    Drug Resist Updat 16:96-107. 2013
    ....
  26. doi request reprint Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans
    Hinrich Schulenburg
    Department of Animal Evolutionary Ecology, Zoological Institute, University of Tuebingen, Auf der Morgenstelle 28, 72076 Tuebingen, Germany
    Immunobiology 213:237-50. 2008
    ..Taken together, our evaluation reveals high potential for immune specificity in C. elegans that may enhance the nematode's ability to fight off pathogens...