Holger Schmid

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. doi request reprint Novel iron-containing phosphate binders for treatment of hyperphosphatemia
    Holger Schmid
    a 1 KFH Nierenzentrum Muenchen Laim, Elsenheimerstr 63, D 80687 Munich, Germany 49 8 95 47 26 70 49 8 95 70 57 27
    Expert Opin Pharmacother 16:2179-91. 2015
  2. pmc Persistent nasal methicillin-resistant staphylococcus aureus carriage in hemodialysis outpatients: a predictor of worse outcome
    Holger Schmid
    KfH Nierenzentrum Muenchen Laim, Elsenheimerstr 36, 80687 Munich, Germany
    BMC Nephrol 14:93. 2013
  3. doi request reprint Peginesatide for the treatment of renal disease-induced anemia
    Holger Schmid
    University of Munich, Department of Internal Medicine, Munich, D 80336, Germany
    Expert Opin Pharmacother 14:937-48. 2013
  4. doi request reprint Macro CK2 accumulation in tenofovir-treated HIV patients is facilitated by CK oligomer stabilization but is not predictive for pathology
    Holger Schmid
    Section of Infectious Diseases, Clinic and Policlinic IV, University of Munich, Munich, Germany
    Antivir Ther 18:193-204. 2013
  5. ncbi request reprint New strategies for managing anemia of chronic kidney disease
    Holger Schmid
    KfH Nierenzentrum München Laim, Munich, Germany
    Cardiovasc Hematol Agents Med Chem 10:339-51. 2012
  6. pmc Adherence to prescribed oral medication in adult patients undergoing chronic hemodialysis: a critical review of the literature
    Holger Schmid
    KfH Nierenzentrum Muenchen Laim, Elsenheimerstr 63, 80687 Munich, Germany
    Eur J Med Res 14:185-90. 2009
  7. ncbi request reprint Ankle and hindfoot arthropathy in hereditary hemochromatosis
    Holger Schmid
    Rheumahaeinheit, Med Poliklinik, Munich, Germany
    J Rheumatol 30:196-9. 2003
  8. doi request reprint Erythropoiesis-stimulating agents, hypertension and left ventricular hypertrophy in the chronic kidney disease patient
    Holger Schmid
    KfH Nierenzentrum Muenchen Laim, Department of Internal Medicine, University Hospital Munich, University of Munich, Munich, Germany
    Curr Opin Nephrol Hypertens 20:465-70. 2011
  9. ncbi request reprint Clinical management of large adrenal cystic lesions
    Holger Schmid
    Medizinische Poliklinik, Universitat Munchen, Pettenkoferstrasse 8a, D 80336, Munich, Germany
    Int Urol Nephrol 37:767-71. 2005
  10. ncbi request reprint Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy
    Maja T Lindenmeyer
    Nephrologisches Zentrum, Medizinische Poliklinik, University of Munich, Pettenkoferstrasse 8a, 80336 Munich, Germany
    J Am Soc Nephrol 18:1765-76. 2007

Collaborators

Detail Information

Publications46

  1. doi request reprint Novel iron-containing phosphate binders for treatment of hyperphosphatemia
    Holger Schmid
    a 1 KFH Nierenzentrum Muenchen Laim, Elsenheimerstr 63, D 80687 Munich, Germany 49 8 95 47 26 70 49 8 95 70 57 27
    Expert Opin Pharmacother 16:2179-91. 2015
    ..The iron-containing PB sucroferric oxyhydroxide (SO) and ferric citrate hydrate (FCH) have entered the market and other candidates are prior market entry...
  2. pmc Persistent nasal methicillin-resistant staphylococcus aureus carriage in hemodialysis outpatients: a predictor of worse outcome
    Holger Schmid
    KfH Nierenzentrum Muenchen Laim, Elsenheimerstr 36, 80687 Munich, Germany
    BMC Nephrol 14:93. 2013
    ....
  3. doi request reprint Peginesatide for the treatment of renal disease-induced anemia
    Holger Schmid
    University of Munich, Department of Internal Medicine, Munich, D 80336, Germany
    Expert Opin Pharmacother 14:937-48. 2013
    ..Peginesatide, recently approved in the US for once-monthly dosing in adult patients on dialysis, is a promising novel PEGylated erythropoietin-mimetic peptide for the treatment of renal disease-induced anemia...
  4. doi request reprint Macro CK2 accumulation in tenofovir-treated HIV patients is facilitated by CK oligomer stabilization but is not predictive for pathology
    Holger Schmid
    Section of Infectious Diseases, Clinic and Policlinic IV, University of Munich, Munich, Germany
    Antivir Ther 18:193-204. 2013
    ..The genesis and clinical significance of this finding is unclear...
  5. ncbi request reprint New strategies for managing anemia of chronic kidney disease
    Holger Schmid
    KfH Nierenzentrum München Laim, Munich, Germany
    Cardiovasc Hematol Agents Med Chem 10:339-51. 2012
    ....
  6. pmc Adherence to prescribed oral medication in adult patients undergoing chronic hemodialysis: a critical review of the literature
    Holger Schmid
    KfH Nierenzentrum Muenchen Laim, Elsenheimerstr 63, 80687 Munich, Germany
    Eur J Med Res 14:185-90. 2009
    ....
  7. ncbi request reprint Ankle and hindfoot arthropathy in hereditary hemochromatosis
    Holger Schmid
    Rheumahaeinheit, Med Poliklinik, Munich, Germany
    J Rheumatol 30:196-9. 2003
    ..Other differential diagnoses could be excluded. Severe arthropathy of the ankle and hindfoot in comparatively young men can be a leading presentation of HH...
  8. doi request reprint Erythropoiesis-stimulating agents, hypertension and left ventricular hypertrophy in the chronic kidney disease patient
    Holger Schmid
    KfH Nierenzentrum Muenchen Laim, Department of Internal Medicine, University Hospital Munich, University of Munich, Munich, Germany
    Curr Opin Nephrol Hypertens 20:465-70. 2011
    ..Numerous noninterventional studies in patients with chronic kidney disease (CKD) revealed a consistent relationship of LVH with modifiable risk factors attributable to failing renal function, particularly anemia and hypertension...
  9. ncbi request reprint Clinical management of large adrenal cystic lesions
    Holger Schmid
    Medizinische Poliklinik, Universitat Munchen, Pettenkoferstrasse 8a, D 80336, Munich, Germany
    Int Urol Nephrol 37:767-71. 2005
    ..En bloc adrenalectomy, preferably by a laparoscopic approach, has become the treatment of choice...
  10. ncbi request reprint Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy
    Maja T Lindenmeyer
    Nephrologisches Zentrum, Medizinische Poliklinik, University of Munich, Pettenkoferstrasse 8a, 80336 Munich, Germany
    J Am Soc Nephrol 18:1765-76. 2007
    ..These findings and the questions about rodent models in DN raise a note of caution regarding the proposal to inhibit VEGF-A to prevent progression of DN...
  11. ncbi request reprint Binding of the chemokine SLC/CCL21 to its receptor CCR7 increases adhesive properties of human mesangial cells
    Bernhard Banas
    Nephrologisches Zentrum, Medizinische Poliklinik, Ludwig Maximilians Universitat Munchen, Germany
    Kidney Int 66:2256-63. 2004
    ..In leukocytes chemokines mediate integrin-dependent firm adhesion. Therefore, we examined the influence of chemokine receptor CCR7 activation by SLC/CCL21 on adhesive properties of human mesangial cells to matrix molecules...
  12. ncbi request reprint Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy
    Holger Schmid
    Division of Nephrology, Medizinische Poliklinik, University of Munich, Pettenkoferstr 8a, 80336 Munich, Germany
    Diabetes 55:2993-3003. 2006
    ....
  13. doi request reprint Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy
    Andrea Ribeiro
    Medizinische Poliklinik Campus Innenstadt, Klinikum der LMU, Munich, Germany
    Kidney Int 81:100-11. 2012
    ..Thus, PVAN activation of innate immune defense mechanisms through TLR3 is involved in the antiviral and anti-inflammatory response leading to the expression of proinflammatory cytokines and chemokines...
  14. ncbi request reprint Expression of the chemokine receptor CCR1 in human renal allografts
    Verena Mayer
    Medizinische Poliklinik Innenstadt, Pettenkoferstrasse 8a, 80336 Munich, Germany
    Nephrol Dial Transplant 22:1720-9. 2007
    ..CCR1 is a receptor for various proinflammatory chemokines and CCR1 blockade reduces renal allograft injury in rabbits. The purpose of the study was to characterize CCR1-positive cells in human renal allografts...
  15. ncbi request reprint Macroenzyme creatine kinase (CK) type 2 in HIV-infected patients is significantly associated with TDF and consists of ubiquitous mitochondrial CK
    Holger Schmid
    Medizinische Poliklinik, Ludwig Maximilians University Munich, Germany
    Antivir Ther 11:1071-80. 2006
    ..To evaluate the prevalence and origin of macroenzyme creatine kinase type 2 (Macro CK2) in HIV-1-infected patients on antiretroviral treatment...
  16. pmc Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice
    Volha Ninichuk
    Nephrological Center, Medical Policlinic, University of Munich, Munich, Germany
    Am J Pathol 172:628-37. 2008
    ....
  17. pmc Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins
    Clemens D Cohen
    Medizinische Poliklinik, University of Munich, 80336 Munich, Germany
    Proc Natl Acad Sci U S A 103:5682-7. 2006
    ..Nephrin, ZO-1, and cadherin-5 mRNA showed stringent coexpression across a diverse set of human glomerular diseases. Comparative promoter analysis can identify regulatory pathways at work in tissue homeostasis and disease processes...
  18. pmc Effects of chemokines on proliferation and apoptosis of human mesangial cells
    Markus Wornle
    Medical Policlinic, Ludwig Maximilians University, Munich, Germany
    BMC Nephrol 5:8. 2004
    ..g. SLC/CCL21 on podocytes and CCR7 on MC is suggested to play a pivotal role during these processes. Therefore the effect of selected chemokines on MC proliferation and apoptosis was studied...
  19. doi request reprint Pharmacotherapy of end-stage renal disease
    Holger Schmid
    KfH Nierenzentrum Muenchen Laim, Elsenheimerstrasse 63, D 80687 Munich, Germany
    Expert Opin Pharmacother 11:597-613. 2010
    ..The incidence and prevalence of end-stage renal disease (ESRD) requiring renal replacement therapy (RRT) continues to grow worldwide. ESRD causes significant morbidity and mortality and has enormous financial and personal costs...
  20. doi request reprint Novel role of toll-like receptor 3, RIG-I and MDA5 in poly (I:C) RNA-induced mesothelial inflammation
    Markus Wornle
    Medical Policlinic, Ludwig Maximilians University, Pettenkoferstrasse 8a, 80336, Munich, Germany
    Mol Cell Biochem 322:193-206. 2009
    ..This novel finding of functional expression of viral sensors on human MC may indicate a novel link between viral infections and mesothelial inflammation and indicates a pathophysiologic role of viral receptors in these processes...
  21. ncbi request reprint Molecular approaches to chronic kidney disease
    Holger Schmid
    Medizinische Poliklinik, Klinikum der Universitat Munchen, Munich, Germany
    Curr Opin Nephrol Hypertens 15:123-9. 2006
    ..Current approaches to identifying the molecular markers required to implement this 'personalized medicine' concept in progressive renal failure will be presented in this review...
  22. ncbi request reprint Chemokine receptor Ccr2 deficiency reduces renal disease and prolongs survival in MRL/lpr lupus-prone mice
    Guillermo Perez de Lema
    Klinikum der Universitat Munchen, Medizinische Poliklinik Innenstadt, Munich, Germany
    J Am Soc Nephrol 16:3592-601. 2005
    ..These results identify Ccr2 as an additional possible target for the treatment of lupus nephritis...
  23. ncbi request reprint CD20-positive infiltrates in human membranous glomerulonephritis
    Clemens D Cohen
    Medizinische Poliklinik, Nephrologisches Zentrum, Ludwig Maximilians University, Munich, Germany
    J Nephrol 18:328-33. 2005
    ....
  24. ncbi request reprint Expression of HIF-1alpha in injured arteries controls SDF-1alpha mediated neointima formation in apolipoprotein E deficient mice
    Ela Karshovska
    Division of Cardiology, Medizinische Poliklinik, University of Munich, Pettenkoferstrasse 8a, 80336 Munich, Germany
    Arterioscler Thromb Vasc Biol 27:2540-7. 2007
    ..Because HIF-1alpha can be activated under normoxic conditions in smooth muscle cells (SMCs) by platelet products, we investigated the role of HIF-1alpha in SDF-1alpha-mediated neointima formation after vascular injury...
  25. ncbi request reprint Gene expression fingerprints in human tubulointerstitial inflammation and fibrosis as prognostic markers of disease progression
    Anna Henger
    Medical Policlinic, University of Munich, Munich, Germany
    Kidney Int 65:904-17. 2004
    ..To test molecular based renal disease categorization, differential gene expression profiles were compared between control and hydronephrotic kidneys showing varying degrees of inflammation and fibrosis...
  26. ncbi request reprint Polyomavirus DNA and RNA detection in renal allograft biopsies: results from a European multicenter study
    Holger Schmid
    Medizinische Poliklinik, Ludwig Maximilians University, Munich, Germany
    Transplantation 80:600-4. 2005
    ..BKV DNA and RNA were detected in biopsy tissues from patients with inconspicuous light microscopy for BKVAN. Further studies will evaluate the potential of intrarenal viral BKV RNA as an early predictor for BKVAN...
  27. ncbi request reprint Erythropoiesis stimulating agents and anaemia of end-stage renal disease
    Holger Schmid
    KfH Nierenzentrum Muenchen Laim, Munich, Germany
    Cardiovasc Hematol Agents Med Chem 8:164-72. 2010
    ..The use of ESAs does carry risks such as hypertension, pure red cell aplasia, or cancer, and these agents need to be used judiciously...
  28. ncbi request reprint Gene expression analysis of human renal biopsies: recent developments towards molecular diagnosis of kidney disease
    Anna Henger
    Nephrologisches Zentrum, Medizinische Poliklinik, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Curr Opin Nephrol Hypertens 13:313-8. 2004
    ..Recent progress in gene expression-based tissue analysis may provide fundamentally novel information in renal biopsy interpretation. In this review, progress towards the routine application of this approach is summarized...
  29. doi request reprint An orally active chemokine receptor CCR2 antagonist prevents glomerulosclerosis and renal failure in type 2 diabetes
    Sufyan G Sayyed
    Nephrologisches Zentrum, Medizinische Poliklinik, University of Munich, Germany
    Kidney Int 80:68-78. 2011
    ..This successful pre-clinical trial suggests that this antagonist may now be ready for testing in humans with the nephropathy of diabetes mellitus...
  30. ncbi request reprint Sam68-like mammalian protein 2, identified by digital differential display as expressed by podocytes, is induced in proteinuria and involved in splice site selection of vascular endothelial growth factor
    Clemens D Cohen
    Medizinische Poliklinik, Ludwig Maximilians University, Pettenkoferstrasse 8a, Munich, 80336, Germany
    J Am Soc Nephrol 16:1958-65. 2005
    ..SLM-2-dependent VEGF splicing indicates the importance of mRNA splice site selection for glomerular filtration barrier function...
  31. doi request reprint Hemodiafiltration and survival of end-stage renal disease patients: the long journey goes on
    Holger Schmid
    Department of Internal Medicine IV Campus Innenstadt, University of Munich, Munich, Germany
    Int Urol Nephrol 44:1435-40. 2012
    ..There is an urgent need for further randomized controlled trials to confirm previous findings and to identify those ESRD patients that are likely to benefit mostly from HDF...
  32. pmc Occurrence of HSV-1-induced pneumonitis in patients under standard immunosuppressive therapy for rheumatic, vasculitic, and connective tissue disease
    Matthias N Witt
    Department of Nephrology, Medical Policlinic, University of Munich, Munich, Germany
    BMC Pulm Med 9:22. 2009
    ....
  33. ncbi request reprint Galectin-1 influences migration of retinal pigment epithelial cells
    Claudia S Alge
    Department of Ophthalmology, Ludwig Maximilians University, Munich, Germany
    Invest Ophthalmol Vis Sci 47:415-26. 2006
    ..To determine whether the beta-galactoside-binding matricellular protein Gal-1 is expressed in human specimens of proliferative vitreoretinopathy (PVR) and to evaluate its influence on RPE migration...
  34. ncbi request reprint Validation of endogenous controls for gene expression analysis in microdissected human renal biopsies
    Holger Schmid
    Medizinische Poliklinik, Ludwig Maximilians University of Munich, Munich, Germany
    Kidney Int 64:356-60. 2003
    ..The appropriate choice of an internal reference is critical for quantitative RNA analysis. However, no comparison of frequently used "housekeeping" genes is available for renal biopsy studies...
  35. ncbi request reprint Mycophenolate acid inhibits endothelial NAD(P)H oxidase activity and superoxide formation by a Rac1-dependent mechanism
    Florian Krotz
    Institute of Physiology, Medical Policlinic, Ludwig Maximilians University, Munich, Germany
    Hypertension 49:201-8. 2007
    ....
  36. ncbi request reprint Gene expression profiles of podocyte-associated molecules as diagnostic markers in acquired proteinuric diseases
    Holger Schmid
    Medizinische Poliklinik, Ludwig Maximilians University of Munich, Munich, Germany
    J Am Soc Nephrol 14:2958-66. 2003
    ..As the above approach can be performed as an add-on diagnostic tool, these molecular diagnostic parameters could give novel information for the management of proteinuric diseases...
  37. ncbi request reprint Mycoplasma pneumoniae: usual suspect and unsecured diagnosis in the acute setting
    Gerald S Braun
    Department of Medicine, Medical Policlinic, Ludwig Maximilians Universitat, Munich, Germany
    J Emerg Med 30:371-5. 2006
    ..Disease presentation, complications, diagnostic means, therapeutic options, and suspicious clinical settings are discussed to provide a review on the clinical aspects of the disease that are important in the ED setting...
  38. pmc CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis
    Stephan Segerer
    Medizinische Poliklinik Innenstadt, University of Munich, Munich, Germany
    Am J Pathol 164:635-49. 2004
    ..Therefore interstitial CXCR3, as well as CCR5-positive T cells might play an important role during progressive loss of renal function, and are potential therapeutic targets in human glomerular diseases...
  39. ncbi request reprint Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy
    Vincent Dolan
    Department of Medicine, The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Mater Misericordiae University Hospital, Dublin, Ireland
    Am J Kidney Dis 45:1034-9. 2005
    ..We report the induction of gremlin, a bone morphogenetic protein antagonist, in cultured human mesangial cells exposed to high glucose and transforming growth factor beta (TGF-beta) levels in vitro and kidneys from diabetic rats in vivo...
  40. pmc Novel role of toll-like receptor 3 in hepatitis C-associated glomerulonephritis
    Markus Wornle
    Medical Policlinic, Ludwig Maximilians University, Munchen, Germany
    Am J Pathol 168:370-85. 2006
    ..Thus, TLR3 expression on renal cells, and especially MCs, may establish a link between viral infections and glomerular diseases...
  41. pmc Influence of native and hypochlorite-modified low-density lipoprotein on gene expression in human proximal tubular epithelium
    Stefan Porubsky
    Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany
    Am J Pathol 164:2175-87. 2004
    ....
  42. ncbi request reprint Expression of filtrin in human glomerular diseases
    Pekka Ihalmo
    Department of Bacteriology and Immunology, Haartman Institute, Biomedicum Helsinki, University of Helsinki, Finland, and Renal Immunopathology Laboratory, Fondazione D Amico per la Ricerca sulle Malattie Renali, San Carlo Borromeo Hospital, Milan, Italy
    Nephrol Dial Transplant 22:1903-9. 2007
    ..In this study, the gene and protein expression of filtrin were examined in patients with acquired proteinuric diseases...
  43. ncbi request reprint Gene expression analysis in renal biopsies
    Holger Schmid
    Nephrol Dial Transplant 19:1347-51. 2004
  44. ncbi request reprint Differential expression of profibrotic and growth factors in chronic allograft nephropathy
    Hilary Hotchkiss
    Pediatric Nephrology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Transplantation 81:342-9. 2006
    ..Chronic allograft nephropathy (CAN) is a multifactorial process, where both immunological and nonimmunological factors play roles. Microarrays detect thousands of genes simultaneously...
  45. pmc IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis
    Madeline Murphy
    UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
    J Am Soc Nephrol 19:1672-80. 2008
    ..In summary, IHG-1, which increases in diabetic nephropathy, may enhance the actions of TGF-beta1 and contribute to the development of tubulointerstitial fibrosis...
  46. ncbi request reprint Retinoic acid treatment protects MRL/lpr lupus mice from the development of glomerular disease
    Guillermo Perez de Lema
    Medizinische Poliklinik der Ludwig Maximilians Universität, Munchen, Germany
    Kidney Int 66:1018-28. 2004
    ..Retinoic acid (tRA) is an active metabolite of vitamin A with potent anti-inflammatory properties. We analyzed the effects of tRA on the development of lupus nephritis in MRL/lpr mice...