Moritz Schmelzle

Summary

Affiliation: University of Leipzig
Country: Germany

Publications

  1. pmc Increased plasma levels of microparticles expressing CD39 and CD133 in acute liver injury
    Moritz Schmelzle
    The Transplant Institute and Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, USA
    Transplantation 95:63-9. 2013
  2. pmc The collateral caval shunt as an alternative to classical shunt procedures in patients with recurrent duodenal varices and extrahepatic portal vein thrombosis
    Hans Michael Hau
    Department of Visceral, Transplantation, Vascular and Thoracic Surgery, University Hospital of Leipzig, Liebigstrasse 20, 04103 Leipzig, Germany
    Eur J Med Res 19:36. 2014
  3. pmc Early prediction of survival after open surgical repair of ruptured abdominal aortic aneurysms
    Felix Krenzien
    Department of Visceral, Transplantation, Thoracic and Vascular Surgery, University Hospital of Leipzig, Leipzig, Germany
    BMC Surg 14:92. 2014
  4. pmc CD39 modulates hematopoietic stem cell recruitment and promotes liver regeneration in mice and humans after partial hepatectomy
    Moritz Schmelzle
    Department of Medicine, Liver Center and Transplantation Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA02115, USA
    Ann Surg 257:693-701. 2013
  5. pmc Pulmonary natural killer T cells play an essential role in mediating hyperoxic acute lung injury
    Martina Nowak-Machen
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am J Respir Cell Mol Biol 48:601-9. 2013
  6. doi request reprint Sublethal heat treatment promotes epithelial-mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma
    Shuhei Yoshida
    Division of Gastroenterology and Liver Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
    Hepatology 58:1667-80. 2013
  7. pmc Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/ENTPD1 null mice
    Xiaofeng Sun
    Department of Medicine, Gastroenterology Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Hepatology 57:205-16. 2013

Collaborators

  • Miroslaw Kornek
  • Detlef Schuppan
  • Yu Chen
  • Michael W Donnino
  • Sven Jonas
  • GYORGY BAFFY
  • Hans Michael Hau
  • Felix Krenzien
  • Eva Csizmadia
  • Yan Wu
  • Simon C Robson
  • Georg Wiltberger
  • Martina Nowak-Machen
  • Xiaofeng Sun
  • Shuhei Yoshida
  • Udo X Kaisers
  • Peter Fellmer
  • Peter T Fellmer
  • Ivan Matia
  • Albrecht Hoffmeister
  • Mehmet Haluk Morgul
  • Markus B Schoenberg
  • Leo Otterbein
  • Mark Exley
  • Elliot B Tapper
  • Michail Sitkovsky
  • Linglin Li
  • Ryota Masuzaki
  • Wolfgang Junger
  • Pankaj Seth
  • Lihui Han
  • Glen Doherty
  • Anny Usheva
  • Shu Bian
  • Wolfgang G Junger
  • Dusan Hanidziar
  • Vikas P Sukhatme
  • Naoki Ikenaga

Detail Information

Publications7

  1. pmc Increased plasma levels of microparticles expressing CD39 and CD133 in acute liver injury
    Moritz Schmelzle
    The Transplant Institute and Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, USA
    Transplantation 95:63-9. 2013
    ..Here, we tested whether CD133 MP might be shed in a CD39-dependent manner in a model of liver injury and could potentially serve as biomarkers of liver failure in the clinic...
  2. pmc The collateral caval shunt as an alternative to classical shunt procedures in patients with recurrent duodenal varices and extrahepatic portal vein thrombosis
    Hans Michael Hau
    Department of Visceral, Transplantation, Vascular and Thoracic Surgery, University Hospital of Leipzig, Liebigstrasse 20, 04103 Leipzig, Germany
    Eur J Med Res 19:36. 2014
    ..In this study, we represent a case of recurrent bleeding of duodenal varices in a non-cirrhotic patient with cavernous transformation of the portal vein that was successfully treated with a collateral caval shunt operation...
  3. pmc Early prediction of survival after open surgical repair of ruptured abdominal aortic aneurysms
    Felix Krenzien
    Department of Visceral, Transplantation, Thoracic and Vascular Surgery, University Hospital of Leipzig, Leipzig, Germany
    BMC Surg 14:92. 2014
    ..However, the importance in patients with ruptured abdominal aortic aneurysm (RAAA) remains unclear. Our aim was to analyze scoring systems as predictors of survival in patients undergoing open surgical repair (OSR) for RAAA...
  4. pmc CD39 modulates hematopoietic stem cell recruitment and promotes liver regeneration in mice and humans after partial hepatectomy
    Moritz Schmelzle
    Department of Medicine, Liver Center and Transplantation Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA02115, USA
    Ann Surg 257:693-701. 2013
    ..To study molecular mechanisms involved in hematopoietic stem cell (HSC) mobilization after liver resection and determine impacts on liver regeneration...
  5. pmc Pulmonary natural killer T cells play an essential role in mediating hyperoxic acute lung injury
    Martina Nowak-Machen
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am J Respir Cell Mol Biol 48:601-9. 2013
    ..In conclusion, our data suggest that iNKT cells and purinergic signaling should be evaluated as potential novel therapeutic targets to prevent hyperoxic lung injury...
  6. doi request reprint Sublethal heat treatment promotes epithelial-mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma
    Shuhei Yoshida
    Division of Gastroenterology and Liver Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
    Hepatology 58:1667-80. 2013
    ..Blocking Erk1/2 reduced proliferation and EMT-like changes of heat-treated HCC cells. Implantation of heat-exposed HEPG2 cells into nude mice induced significantly larger, more aggressive tumors than untreated cells...
  7. pmc Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/ENTPD1 null mice
    Xiaofeng Sun
    Department of Medicine, Gastroenterology Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Hepatology 57:205-16. 2013
    ..Exogenous adenosine 5'-triphosphate (ATP) boosts these signaling pathways, whereas rapamycin inhibits such aberrant responses in hepatocytes...