Johannes Carolus Magnus Schlachetzki
Affiliation: University of Erlangen-Nuremberg
- Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microgliaAntonio C P de Oliveira
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstr, 5, D 79104 Freiburg, Germany
J Neuroinflammation 9:2. 2012....
- Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE2 in primary rat microgliaJohannes C M Schlachetzki
Department of Psychiatry and Psychotherapy, University Hospital of Freiburg, Freiburg, Germany
J Neuroinflammation 7:2. 2010..In the present study, we investigate the role of norepinephrine on cyclooxygenase- (COX-)2 expression/synthesis and prostaglandin (PG)E2 production in rat primary microglia...
- Frequency of progranulin mutations in a German cohort of 79 frontotemporal dementia patientsJohannes Carolus Magnus Schlachetzki
Memory Clinic, Center for Geriatrics and Gerontology Freiburg, University Hospital Freiburg, Lehener Str 88, 79106 Freiburg, Germany
J Neurol 256:2043-51. 2009..We also performed quantitative PCR analyses to detect potential whole progranulin gene and exon deletions. Here, results were negative...
- Microglial activation in Alzheimer's diseaseJohannes C M Schlachetzki
Center for Geriatrics and Gerontology Freiburg, University Hospital of Freiburg, Lehenerstr 88, 79106 Freiburg, Germany
Curr Alzheimer Res 6:554-63. 2009..A possible disease modifying role of blood-borne monocytes, which are close relatives of bone-marrow derived microglia, will also be addressed...